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mitomycin and Macular Degeneration

mitomycin has been researched along with Macular Degeneration in 5 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Research Excerpts

ExcerptRelevanceReference
"A pars plana vitrectomy was performed in 12 eyes, and two neurosensory retinal detachments per eye were created by injecting 10(-3) mg/ml mitomycin C and 0."3.69Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration. ( Del Priore, LV; Hornbeck, R; Jones, Z; Kaplan, HJ; Swinn, M, 1996)
"To assess the efficacy of a bleb revision technique with regard to improvement in intraocular pressure (IOP) and visual acuity after hypotony maculopathy and to evaluate the influence of duration of hypotony on visual outcome."1.32Bleb revision for hypotony maculopathy after trabeculectomy. ( Bashford, KP; Shafranov, G; Shields, MB, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bashford, KP1
Shafranov, G1
Shields, MB1
Del Priore, LV1
Kaplan, HJ1
Hornbeck, R1
Jones, Z1
Swinn, M1
Ayyala, RS1
Urban, RC1
Krishnamurthy, MS1
Mendelblatt, DJ1
Singh, K1
Byrd, S1
Egbert, PR1
Budenz, D1
Yasukawa, T1
Kimura, H1
Tabata, Y1
Miyamoto, H1
Honda, Y1
Ikada, Y1
Ogura, Y1

Trials

1 trial available for mitomycin and Macular Degeneration

ArticleYear
Risk of hypotony after primary trabeculectomy with antifibrotic agents in a black west African population.
    Journal of glaucoma, 1998, Volume: 7, Issue:2

    Topics: Fluorouracil; Follow-Up Studies; Ghana; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Intraope

1998

Other Studies

4 other studies available for mitomycin and Macular Degeneration

ArticleYear
Bleb revision for hypotony maculopathy after trabeculectomy.
    Journal of glaucoma, 2004, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blister; Combined Modality Therapy; Female; Humans; Intr

2004
Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration.
    American journal of ophthalmology, 1996, Volume: 122, Issue:5

    Topics: Animals; Atrophy; Bruch Membrane; Capillaries; Cell Division; Choroid; Debridement; Disease Models,

1996
Corneal blood staining following autologous blood injection for hypotony maculopathy.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:10

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Blood; Cornea; Follow-Up Studies; Glauc

1997
Active drug targeting with immunoconjugates to choroidal neovascularization.
    Current eye research, 2000, Volume: 21, Issue:6

    Topics: Aged; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Division; Cells, Cultured; Choroidal Neova

2000