Page last updated: 2024-11-06

mitomycin and Leukoma

mitomycin has been researched along with Leukoma in 59 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the safety and efficacy of 5 seconds of mitomycin-C (MMC) application during photorefractive keratectomy (PRK) for low myopia."9.17Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia. ( Almasi-Nasrabadi, M; Eslani, M; Ramezanzadeh, M; Rezazadeh, P; Shojaei, A; Soleyman-Jahi, S, 2013)
"To study the effect of prophylactic application of mitomycin-C on haze formation in photorefractive keratectomy (PRK) for high myopia."9.11Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study. ( Fotouhi, A; Hashemi, H; Kheiltash, A; Taheri, SM, 2004)
"This review details the current understanding of the mechanism of action and corneal effects of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive keratectomy (PRK), and includes discussion of available information on dosage and exposure time recommended for MMC during PRK."9.05Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK. ( Carlos de Oliveira, R; Wilson, SE, 2020)
"To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus."7.88Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus. ( Li, Z; Mu, G; Pu, W; Tao, X; Xie, Y; Xu, H; Xu, L; Xu, Y; Zhu, W, 2018)
"To present a case of photorefractive keratectomy (PRK) with adjunctive topical mitomycin C (MMC) in an anisometropic hyperopic patient after penetrating keratoplasty (PKP) for keratoconus."7.72Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus. ( Donnenfeld, ED; Perry, HD; Solomon, R; Stein, J; Thimons, J, 2004)
" However, for moderate myopia and shallow depth, low dosing appears to be equally effective."5.35Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia. ( Krueger, RR; Thornton, I; Xu, M, 2008)
"To evaluate the safety and efficacy of 5 seconds of mitomycin-C (MMC) application during photorefractive keratectomy (PRK) for low myopia."5.17Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia. ( Almasi-Nasrabadi, M; Eslani, M; Ramezanzadeh, M; Rezazadeh, P; Shojaei, A; Soleyman-Jahi, S, 2013)
"To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction of myopia."5.14One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK. ( Campos, M; Wallau, AD, 2009)
"To evaluate the anti-haze effect and visual outcome after intraoperative mitomycin C (MMC) use during photorefractive keratectomy (PRK) in myopia or myopic astigmatism patients."5.12Mitomycin C for the prevention of corneal haze in photorefractive keratectomy: a meta-analysis and trial sequential analysis. ( Chang, YM; Chien, KH; Lee, CH; Liang, CM; Weng, TH, 2021)
"To study the effect of prophylactic application of mitomycin-C on haze formation in photorefractive keratectomy (PRK) for high myopia."5.11Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study. ( Fotouhi, A; Hashemi, H; Kheiltash, A; Taheri, SM, 2004)
"To evaluate the results of the prophylactic use of mitomycin-C to inhibit haze formation after excimer laser photorefractive keratectomy (PRK) for medium and high myopia in eyes that were not good candidates for laser in situ keratomileusis (LASIK)."5.10Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. ( Carones, F; Scandola, E; Vacchini, L; Vigo, L, 2002)
"This review details the current understanding of the mechanism of action and corneal effects of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive keratectomy (PRK), and includes discussion of available information on dosage and exposure time recommended for MMC during PRK."5.05Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK. ( Carlos de Oliveira, R; Wilson, SE, 2020)
"To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus."3.88Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus. ( Li, Z; Mu, G; Pu, W; Tao, X; Xie, Y; Xu, H; Xu, L; Xu, Y; Zhu, W, 2018)
"To assess visual results and compare methods of measuring central corneal thickness (CCT) and corneal opacity thickness (COT) in patients with corneal opacities induced by epidemic keratoconjunctivitis (EKC) and treated with phototherapeutic keratectomy (PTK) using low-dose mitomycin C (MMC)."3.77Phototherapeutic keratectomy for the treatment of corneal opacities after epidemic keratoconjunctivitis. ( Allemann, N; Campos, M; Ferraz, CA; Hazarbassanov, RM; Yamazaki, ES, 2011)
"Two patients experienced decreased visual acuity in 1 eye arising from elevated corneal opacity about 12 months after uneventful LASEK with intraoperative mitomycin C application."3.77Recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy with mitomycin C treatment. ( Kim, DY; Kim, JH; Kim, JY; Kim, MJ; Tchah, H, 2011)
"To evaluate the effect of mitomycin C (MMC) on the exacerbation of corneal opacity that occurs in patients with granular corneal dystrophy type II (GCD II) after refractive corneal surface ablation."3.76Mitomycin C does not inhibit exacerbation of granular corneal dystrophy type II induced by refractive surface ablation. ( Cho, HS; Choi, SI; Ha, BJ; Kim, EK; Kim, TI; Lee, DH; Stulting, RD, 2010)
"To retrospectively assess risk factors other than high myopia for corneal haze in patients who had conventional photorefractive keratectomy (PRK) without mitomycin-C (MMC)."3.74Astigmatism: risk factor for postoperative corneal haze in conventional myopic photorefractive keratectomy. ( Brunstetter, T; Rogers, S; Sheridan, MV; Thomas, KE, 2008)
"To present a case of photorefractive keratectomy (PRK) with adjunctive topical mitomycin C (MMC) in an anisometropic hyperopic patient after penetrating keratoplasty (PKP) for keratoconus."3.72Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus. ( Donnenfeld, ED; Perry, HD; Solomon, R; Stein, J; Thimons, J, 2004)
"This could explain the recurrences after surgical removal."2.82[Surgical removal of Salzmann's nodules using intraoperative mitomycin C]. ( Böhringer, D; Eberwein, P; Maier, P; Reinhard, T; Widmer, D, 2016)
" New findings regarding the penetration of MMC to the endothelium and into the aqueous humor may lead surgeons to reassess appropriate dosing and patient selection when the drug is used for surgery."2.46Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery. ( Shah, RA; Wilson, SE, 2010)
" Furthermore, SAHA dosing did not compromise corneal endothelial phenotype, density, or function in rabbit eyes, whereas MMC application did (P < ."1.46Efficacy and Safety Comparison Between Suberoylanilide Hydroxamic Acid and Mitomycin C in Reducing the Risk of Corneal Haze After PRK Treatment In Vivo. ( Anumanthan, G; Gupta, S; Hamm, CW; Hesemann, NP; Mohan, RR; Sharma, A; Waggoner, M, 2017)
"To evaluate the visual outcomes, recurrence patterns, safety, and efficacy of excimer laser phototherapeutic keratectomy (PTK) in conjunction with mitomycin C (MMC) for corneal macular and granular diystrophies."1.43Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies. ( Bilgihan, K; Cubuk, MO; Eroglu, HY; Yuksel, E, 2016)
"Mitomycin C was applied immediately after laser ablation."1.35Mitomycin C in photorefractive keratectomy. ( Gimbel, HV; Kaye, GB; Shalaby, A, 2009)
" However, for moderate myopia and shallow depth, low dosing appears to be equally effective."1.35Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia. ( Krueger, RR; Thornton, I; Xu, M, 2008)
"Mitomycin C treatment induces apoptosis of keratocytes and myofibroblasts, but the predominate effect in inhibiting or treating haze appears to be at the level of blocked replication of keratocytes or other progenitor cells of myofibroblasts."1.33Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. ( Gupta, PC; Mohan, RR; Netto, MV; Sharma, A; Sinha, S; Wilson, SE, 2006)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (3.39)18.2507
2000's30 (50.85)29.6817
2010's22 (37.29)24.3611
2020's5 (8.47)2.80

Authors

AuthorsStudies
Charpentier, S1
Keilani, C1
Maréchal, M1
Friang, C1
De Faria, A1
Froussart-Maille, F1
Delbarre, M1
Carlos de Oliveira, R1
Wilson, SE4
Sudanaboina, P1
Murthy, SI1
Rathi, VM1
Chang, YM1
Liang, CM1
Weng, TH1
Chien, KH1
Lee, CH1
Sanchez-Avila, RM1
Uribe-Badillo, EE1
Sanz, JF1
Muruzabal, F1
Jurado, N1
Alfonso-Bartolozzi, B1
Alfonso, JF1
Baamonde, B1
Anitua, E1
Merayo-Lloves, J1
Kaiserman, I1
Sadi, N1
Mimouni, M1
Sela, T1
Munzer, G1
Levartovsky, S1
Xu, L1
Tao, X1
Li, Z1
Xu, Y1
Zhu, W1
Xu, H1
Pu, W1
Xie, Y1
Mu, G1
Anumanthan, G1
Sharma, A2
Waggoner, M1
Hamm, CW1
Gupta, S1
Hesemann, NP1
Mohan, RR2
Hofmeister, EM2
Bishop, FM2
Kaupp, SE2
Schallhorn, SC2
Leccisotti, A2
Fields, SV1
Yuksel, E1
Cubuk, MO1
Eroglu, HY1
Bilgihan, K1
Böhringer, D1
Widmer, D1
Eberwein, P1
Maier, P1
Reinhard, T1
Thomas, KE1
Brunstetter, T1
Rogers, S1
Sheridan, MV1
Shalaby, A1
Kaye, GB1
Gimbel, HV1
Salomao, MQ1
Ma, JJ1
Tseng, SS1
Yarascavitch, BA1
Wallau, AD1
Campos, M2
Kim, ST1
Koh, JW1
Yoon, GJ1
Yang, SW1
Virasch, VV1
Majmudar, PA3
Epstein, RJ3
Vaidya, NS1
Dennis, RF3
Hongyok, T1
Kim, A1
Jun, AS1
Ladas, JG1
Chuck, RS1
Ha, BJ1
Kim, TI2
Choi, SI1
Stulting, RD1
Lee, DH1
Cho, HS1
Kim, EK1
Shah, RA1
Liu, A1
Manche, EE1
Khakshoor, H1
Zarei-Ghanavati, M1
Saffarian, L1
Yamazaki, ES1
Ferraz, CA1
Hazarbassanov, RM1
Allemann, N1
Sher, NA1
Golben, MP1
Bond, W1
Trattler, WB1
Kim, JH1
Kim, MJ1
Kim, DY1
Kim, JY1
Tchah, H2
De Benito-Llopis, L1
Teus, MA1
Drake-Casanova, P1
Yulish, M1
Beiran, I1
Miller, B1
Pikkel, J1
Gomes, BA1
Smadja, D1
Espana, EM1
Ahn, ES1
Netto, MV3
Santhiago, MR1
Shojaei, A1
Ramezanzadeh, M1
Soleyman-Jahi, S1
Almasi-Nasrabadi, M1
Rezazadeh, P1
Eslani, M1
Carones, F1
Vigo, L1
Scandola, E1
Vacchini, L1
Maust, HA1
Raber, IM1
Mirza, MA1
Qazi, MA2
Pepose, JS2
Lai, YH1
Wang, HZ1
Lin, CP1
Chang, SJ1
Hashemi, H1
Taheri, SM1
Fotouhi, A1
Kheiltash, A1
Solomon, R1
Donnenfeld, ED1
Thimons, J1
Stein, J1
Perry, HD1
Gambato, C2
Ghirlando, A2
Moretto, E1
Busato, F1
Midena, E2
Kervick, G1
Kottler, UB1
Dick, HB1
Lee, SY1
Pak, JH1
Kook, MS1
Kymionis, GD1
Pallikaris, IG1
Sinha, S1
Gupta, PC1
Johnson, TW1
Chalita, MR1
Krueger, RR3
Nassaralla, BA1
McLeod, SD1
Nassaralla, JJ1
Thornton, I2
Puri, A1
Xu, M2
Goldsberry, DH1
Epstein, RH1
Holley, G1
Edelhauser, HF1
Miotto, S1
Cortese, M1
Salvi, R1
Gamaly, TO1
El Danasoury, A1
El Maghraby, A1
Nakano, EM1
Bains, HS1
Hirai, FE1
Portellinha, W1
Oliveira, M1
Nakano, K1
Farid, M1
Morishige, N1
Lam, L1
Wahlert, A1
Steinert, RF1
Jester, JV1
Zacharia, PT1
Harrison, DA1
Wheeler, DT1
Mullaney, PB1
Selleck, C1
Al-Awad, A1
Al-Mesfer, S1
Zwaan, J1
Raviv, T1
Winkler von Mohrenfels, C1
Hermann, W1
Gabler, B1
Müller, M1
Marshall, J1
Lohmann, CP1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phototherapeutic Keratectomy With Mitomycin C in Adenoviral Infiltrates[NCT00492245]30 participants (Anticipated)Interventional2006-04-30Active, not recruiting
Two Years Follow up of Corneal Cor Cross-linking and Refractive Surface Ablation in Patients With Asymmetric Corneal Topography[NCT02943967]44 participants (Actual)Interventional2010-01-31Completed
Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C.[NCT00599950]Phase 410 participants (Actual)Interventional2007-01-31Completed
Epi-LASIK : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma.[NCT00599690]10 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for mitomycin and Leukoma

ArticleYear
Corneal haze post photorefractive keratectomy.
    Journal francais d'ophtalmologie, 2021, Volume: 44, Issue:9

    Topics: Cornea; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Photorefractive Keratectomy

2021
Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK.
    Experimental eye research, 2020, Volume: 200

    Topics: Alkylating Agents; Corneal Opacity; Corneal Stroma; Fibrosis; Humans; Lasers, Excimer; Mitomycin; My

2020
Mitomycin C for the prevention of corneal haze in photorefractive keratectomy: a meta-analysis and trial sequential analysis.
    Acta ophthalmologica, 2021, Volume: 99, Issue:6

    Topics: Corneal Opacity; Cross-Linking Reagents; Humans; Mitomycin; Myopia; Photorefractive Keratectomy; Pos

2021
Corneal molecular and cellular biology update for the refractive surgeon.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2009, Volume: 25, Issue:5

    Topics: Alkylating Agents; Apoptosis; Cornea; Corneal Opacity; Corneal Surgery, Laser; Humans; Lasers, Excim

2009
Use of mitomycin-C for phototherapeutic keratectomy and photorefractive keratectomy surgery.
    Current opinion in ophthalmology, 2010, Volume: 21, Issue:4

    Topics: Alkylating Agents; Animals; Astigmatism; Combined Modality Therapy; Corneal Opacity; Humans; Hyperop

2010
[Mitomycin C in refractive corneal surface surgery with the excimer laser: first experience and review of the literature].
    Klinische Monatsblatter fur Augenheilkunde, 2005, Volume: 222, Issue:6

    Topics: Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Corneal Opacity; Humans; Intracellular S

2005

Trials

13 trials available for mitomycin and Leukoma

ArticleYear
Randomized dose-response analysis of mitomycin-C to prevent haze after photorefractive keratectomy for high myopia.
    Journal of cataract and refractive surgery, 2013, Volume: 39, Issue:9

    Topics: Adult; Alkylating Agents; Cell Count; Corneal Endothelial Cell Loss; Corneal Opacity; Dose-Response

2013
[Surgical removal of Salzmann's nodules using intraoperative mitomycin C].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2016, Volume: 113, Issue:9

    Topics: Adult; Aged; Combined Modality Therapy; Corneal Opacity; Follow-Up Studies; Humans; Longitudinal Stu

2016
Mitomycin-C in hyperopic photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2009, Volume: 35, Issue:4

    Topics: Administration, Topical; Adult; Alkylating Agents; Astigmatism; Cell Count; Corneal Opacity; Corneal

2009
One-year outcomes of a bilateral randomised prospective clinical trial comparing PRK with mitomycin C and LASIK.
    The British journal of ophthalmology, 2009, Volume: 93, Issue:12

    Topics: Adult; Biomechanical Phenomena; Combined Modality Therapy; Contrast Sensitivity; Cornea; Corneal Opa

2009
[Effect of mitomycin C on corneal regrowth after laser-assisted sub-epithelial keratectomy (LASEK)].
    Archivos de la Sociedad Espanola de Oftalmologia, 2011, Volume: 86, Issue:7

    Topics: Adult; Cell Division; Corneal Opacity; Female; Fibroblasts; Growth Inhibitors; Humans; Intraoperativ

2011
Ascorbate prophylaxis with mitomycin-C for corneal haze after laser-assisted sub-epithelial keratectomy.
    The Israel Medical Association journal : IMAJ, 2012, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antioxidants; Ascorbic Acid; Astigmatism; Cornea; Corneal Opacity; Drug Therapy,

2012
Short-time mitomycin-C application during photorefractive keratectomy in patients with low myopia.
    Journal of cataract and refractive surgery, 2013, Volume: 39, Issue:2

    Topics: Adult; Alkylating Agents; Cell Count; Cornea; Corneal Opacity; Double-Blind Method; Endothelium, Cor

2013
Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:12

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Cornea; Corneal Opacity; Double-Blind M

2002
Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study.
    BMC ophthalmology, 2004, Sep-14, Volume: 4

    Topics: Adult; Antibiotics, Antineoplastic; Corneal Opacity; Humans; Lasers, Excimer; Middle Aged; Mitomycin

2004
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
    Ophthalmology, 2005, Volume: 112, Issue:2

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Contrast Sensitivity; Cornea; Corneal O

2005
Long-term effects on corneal keratocytes of mitomycin C during photorefractive keratectomy: a randomized contralateral eye confocal microscopy study.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:9 Suppl

    Topics: Administration, Topical; Adult; Cell Count; Cornea; Corneal Opacity; Double-Blind Method; Female; Hu

2007
A prospective, randomized, contralateral eye comparison of epithelial laser in situ keratomileusis and photorefractive keratectomy in eyes prone to haze.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:9 Suppl

    Topics: Adult; Corneal Opacity; Epithelium, Corneal; Female; Humans; Keratomileusis, Laser In Situ; Lasers,

2007
Comparison of laser epithelial keratomileusis with and without mitomycin C for wavefront customized surface ablations.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:9 Suppl

    Topics: Adult; Cell Count; Contrast Sensitivity; Cornea; Corneal Opacity; Diagnostic Techniques, Ophthalmolo

2007

Other Studies

40 other studies available for mitomycin and Leukoma

ArticleYear
Excimer laser phototherapeutic keratectomy with mitomycin C application to treat haze after myopic photorefractive keratectomy.
    Indian journal of ophthalmology, 2020, Volume: 68, Issue:12

    Topics: Alkylating Agents; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefractive Kera

2020
Plasma rich in growth factors versus Mitomycin C in photorefractive keratectomy.
    Medicine, 2021, Jan-22, Volume: 100, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Blood Transfusion, Autologous; Corneal Opacity; Female; Hu

2021
Corneal Breakthrough Haze After Photorefractive Keratectomy With Mitomycin C: Incidence and Risk Factors.
    Cornea, 2017, Volume: 36, Issue:8

    Topics: Adult; Alkylating Agents; Corneal Opacity; Female; Humans; Hyperopia; Incidence; Lasers, Excimer; Ma

2017
Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus.
    Eye & contact lens, 2018, Volume: 44 Suppl 2

    Topics: Adolescent; Adult; Corneal Opacity; Cross-Linking Reagents; Female; Humans; Keratoconus; Male; Mitom

2018
Efficacy and Safety Comparison Between Suberoylanilide Hydroxamic Acid and Mitomycin C in Reducing the Risk of Corneal Haze After PRK Treatment In Vivo.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2017, Dec-01, Volume: 33, Issue:12

    Topics: Alkylating Agents; Animals; Apoptosis; Cornea; Corneal Opacity; Disease Models, Animal; Fluorescent

2017
Reply: To PMID 23830559.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:3

    Topics: Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photor

2014
Mitomycin-C in photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:3

    Topics: Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia; Photor

2014
Excimer laser phototherapeutic keratectomy in conjunction with mitomycin C in corneal macular and granular dystrophies.
    Arquivos brasileiros de oftalmologia, 2016, Volume: 79, Issue:2

    Topics: Adult; Alkylating Agents; Corneal Dystrophies, Hereditary; Corneal Opacity; Female; Follow-Up Studie

2016
Astigmatism: risk factor for postoperative corneal haze in conventional myopic photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2008, Volume: 34, Issue:12

    Topics: Adult; Alkylating Agents; Astigmatism; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Middl

2008
Mitomycin C in photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2009, Volume: 25, Issue:1 Suppl

    Topics: Alkylating Agents; Combined Modality Therapy; Cornea; Corneal Opacity; Humans; Lasers, Excimer; Mito

2009
Anterior segment optical coherence tomography for transepithelial phototherapeutic keratectomy in central corneal stromal scarring.
    Cornea, 2009, Volume: 28, Issue:8

    Topics: Anterior Eye Segment; Cicatrix; Corneal Diseases; Corneal Opacity; Corneal Stroma; Epithelium, Corne

2009
Clinical outcomes of epi-LASIK: 1-year results of on- and off-flap procedures with and without mitomycin-C.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:5

    Topics: Adult; Corneal Opacity; Corneal Topography; Female; Humans; Keratomileusis, Laser In Situ; Male; Mit

2010
Reduced application time for prophylactic mitomycin C in photorefractive keratectomy.
    Ophthalmology, 2010, Volume: 117, Issue:5

    Topics: Adult; Alkylating Agents; Corneal Opacity; Female; Humans; Lasers, Excimer; Male; Mitomycin; Myopia;

2010
Phototherapeutic keratectomy with mitomycin C after Descemet stripping automated endothelial keratoplasty.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:3

    Topics: Aged, 80 and over; Combined Modality Therapy; Corneal Opacity; Descemet Stripping Endothelial Kerato

2010
Mitomycin C does not inhibit exacerbation of granular corneal dystrophy type II induced by refractive surface ablation.
    Cornea, 2010, Volume: 29, Issue:5

    Topics: Adult; Alkylating Agents; Corneal Dystrophies, Hereditary; Corneal Opacity; Female; Humans; Keratect

2010
Visually significant haze after retreatment with photorefractive keratectomy with mitomycin-C following laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:9

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Corneal Opacity; Female; Humans; Keratomileusis

2010
Mechanical superficial keratectomy for corneal haze after photorefractive keratectomy with mitomycin C and extended wear contact lens.
    Cornea, 2011, Volume: 30, Issue:2

    Topics: Administration, Topical; Adult; Contact Lenses, Extended-Wear; Cornea; Corneal Opacity; Female; Foll

2011
Phototherapeutic keratectomy for the treatment of corneal opacities after epidemic keratoconjunctivitis.
    American journal of ophthalmology, 2011, Volume: 151, Issue:1

    Topics: Adenovirus Infections, Human; Adolescent; Adult; Aged; Conjunctivitis, Viral; Contrast Sensitivity;

2011
A retrospective review of photorefractive keratectomy to enhance earlier radial keratotomy.
    International ophthalmology clinics, 2011,Spring, Volume: 51, Issue:2

    Topics: Adult; Aged; Corneal Opacity; Eyeglasses; Female; Humans; Keratotomy, Radial; Male; Middle Aged; Mit

2011
Recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy with mitomycin C treatment.
    Cornea, 2011, Volume: 30, Issue:9

    Topics: Adult; Alkylating Agents; Cicatrix, Hypertrophic; Corneal Opacity; Debridement; Female; Humans; Kera

2011
Very late-onset corneal scar triggered by trauma after photorefractive keratectomy.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:9

    Topics: Alkylating Agents; Cornea; Corneal Injuries; Corneal Opacity; Eye Injuries; Female; Glucocorticoids;

2012
Peripheral hypertrophic subepithelial corneal degeneration.
    Eye & contact lens, 2003, Volume: 29, Issue:4

    Topics: Adult; Androstadienes; Anti-Allergic Agents; Antibiotics, Antineoplastic; Corneal Dystrophies, Hered

2003
Treatment of dense subepithelial corneal haze after laser-assisted subepithelial keratectomy.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:3

    Topics: Adult; Corneal Opacity; Corneal Topography; Debridement; Epithelium, Corneal; Humans; Keratomileusis

2004
Mitomycin C alters corneal stromal wound healing and corneal haze in rabbits after argon-fluoride excimer laser photorefractive keratectomy.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2004, Volume: 20, Issue:2

    Topics: Animals; Apoptosis; Argon; Corneal Opacity; Corneal Stroma; Fluorides; Instillation, Drug; Lasers, E

2004
Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus.
    Eye & contact lens, 2004, Volume: 30, Issue:3

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Corneal Opacity

2004
Subepithelial scarring after laser-assisted subepithelial keratectomy.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:4

    Topics: Corneal Opacity; Corneal Topography; Debridement; Epithelium, Corneal; Humans; Keratectomy, Subepith

2005
Mitomycin C, ceramide, and 5-fluorouracil inhibit corneal haze and apoptosis after PRK.
    Cornea, 2006, Volume: 25, Issue:1

    Topics: Animals; Apoptosis; Ceramides; Cornea; Corneal Opacity; Fluorouracil; Lasers, Excimer; Mitomycin; Ph

2006
Mitomycin C in highly myopic eyes.
    Ophthalmology, 2006, Volume: 113, Issue:2

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Cornea; Corneal Opacity; Humans; Lasers, Excim

2006
Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2006, Volume: 22, Issue:6

    Topics: Animals; Apoptosis; Cell Count; Cell Proliferation; Cornea; Corneal Opacity; Disease Models, Animal;

2006
Development of late-onset subepithelial corneal haze after laser-assisted subepithelial keratectomy with prophylactic intraoperative mitomycin-C Case report and literature review.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:9

    Topics: Adult; Alkylating Agents; Combined Modality Therapy; Corneal Opacity; Debridement; Epithelium, Corne

2006
Corneal haze following PRK with mitomycin C as a retreatment versus prophylactic use in the contralateral eye.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:1

    Topics: Adult; Antibiotics, Antineoplastic; Combined Modality Therapy; Corneal Opacity; Female; Humans; Lase

2007
Prophylactic mitomycin C to inhibit corneal haze after photorefractive keratectomy for residual myopia following radial keratotomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:3

    Topics: Adult; Alkylating Agents; Cell Count; Corneal Opacity; Endothelium, Corneal; Female; Humans; Keratot

2007
Low-dose mitomycin C as a prophylaxis for corneal haze in myopic surface ablation.
    American journal of ophthalmology, 2007, Volume: 144, Issue:5

    Topics: Adolescent; Adult; Cornea; Corneal Opacity; Female; Follow-Up Studies; Humans; Keratectomy, Subepith

2007
Effect of mitomycin C on the corneal endothelium when used for corneal subepithelial haze prophylaxis following photorefractive keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2007, Volume: 23, Issue:7

    Topics: Cell Count; Corneal Opacity; Endothelium, Corneal; Humans; Lasers, Excimer; Mitomycin; Myopia; Nucle

2007
Comparison of standard (0.02%) and low dose (0.002%) mitomycin C in the prevention of corneal haze following surface ablation for myopia.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:1

    Topics: Adult; Alkylating Agents; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Myopia; Photorefracti

2008
Detection of corneal fibrosis by imaging second harmonic-generated signals in rabbit corneas treated with mitomycin C after excimer laser surface ablation.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:10

    Topics: Alkylating Agents; Animals; Combined Modality Therapy; Cornea; Corneal Opacity; Fibrillar Collagens;

2008
Penetrating keratoplasty with a valved glaucoma drainage implant for congenital glaucoma and corneal scarring secondary to hydrops.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:4

    Topics: Administration, Topical; Anterior Chamber; Antibiotics, Antineoplastic; Corneal Edema; Corneal Opaci

1998
Combined trabeculotomy and trabeculectomy as an initial procedure in uncomplicated congenital glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:4

    Topics: Chemotherapy, Adjuvant; Child, Preschool; Corneal Opacity; Female; Glaucoma; Humans; Infant; Infant,

1999
Mytomycin-C for post-PRK corneal haze.
    Journal of cataract and refractive surgery, 2000, Volume: 26, Issue:8

    Topics: Alkylating Agents; Corneal Opacity; Humans; Lasers, Excimer; Mitomycin; Ophthalmic Solutions; Photor

2000
[Topical Mitomycin C for the prophylaxis of recurrent haze after excimer laser photorefractive keratectomy (PRK) - a pilotstudy of 5 patients].
    Klinische Monatsblatter fur Augenheilkunde, 2001, Volume: 218, Issue:12

    Topics: Adult; Corneal Opacity; Female; Follow-Up Studies; Humans; Lasers, Excimer; Male; Mitomycin; Ophthal

2001