mitomycin has been researched along with Leucocythaemia in 22 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since cytochalasin B has shown in vitro efficacy against anchorage-independent growth, as well as against attached malignancies, both U937 human monocytic leukemia and MCF7 human breast carcinoma cells were evaluated." | 3.81 | Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents. ( Fondy, TP; Trendowski, M; Wong, V; Yu, G, 2015) |
| " Conceptually, it is accepted that MTX and folic acid are transported by folate receptors (FRs) in cancerous cells, but the exact mechanism of MTX uptake in human leukemia is unknown." | 3.75 | Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells. ( Biswal, BK; Verma, RS, 2009) |
| "BCR/ABL-positive leukemia cells accumulated more replication-dependent DNA double-strand breaks (DSBs) than normal counterparts after treatment with cisplatin and mitomycin C (MMC, as assessed by pulse field gel electrophoresis (PFGE) and neutral comet assay." | 3.73 | ATR-Chk1 axis protects BCR/ABL leukemia cells from the lethal effect of DNA double-strand breaks. ( Blasiak, J; Czechowska, A; Datta, M; Koptyra, M; Krszyna, K; Nieborowska-Skorska, M; Rink, L; Seferynska, I; Skorski, T; Slupianek, A; Stoklosa, T, 2006) |
| "The generation time of this cancer cell line had a distribution with a long tail and a heritability across generations." | 1.62 | Intrinsic growth heterogeneity of mouse leukemia cells underlies differential susceptibility to a growth-inhibiting anticancer drug. ( Nakaoka, H; Okura, R; Seita, A; Wakamoto, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Awang, K | 1 |
| Lim, CS | 1 |
| Mohamad, K | 1 |
| Morita, H | 1 |
| Hirasawa, Y | 1 |
| Takeya, K | 1 |
| Thoison, O | 1 |
| Hadi, AH | 1 |
| Seita, A | 1 |
| Nakaoka, H | 1 |
| Okura, R | 1 |
| Wakamoto, Y | 1 |
| Trendowski, M | 1 |
| Wong, V | 1 |
| Yu, G | 1 |
| Fondy, TP | 1 |
| Salustiano, EJ | 1 |
| Netto, CD | 1 |
| Fernandes, RF | 1 |
| da Silva, AJ | 1 |
| Bacelar, TS | 1 |
| Castro, CP | 1 |
| Buarque, CD | 1 |
| Maia, RC | 1 |
| Rumjanek, VM | 1 |
| Costa, PR | 1 |
| Biswal, BK | 1 |
| Verma, RS | 1 |
| Blalock, WL | 1 |
| Bavelloni, A | 1 |
| Piazzi, M | 1 |
| Tagliavini, F | 1 |
| Faenza, I | 1 |
| Martelli, AM | 1 |
| Follo, MY | 1 |
| Cocco, L | 1 |
| SAMPEY, JR | 1 |
| HIBINO, S | 1 |
| ISHIBASHI, Y | 1 |
| WAKISAKA, G | 1 |
| UCHINO, H | 1 |
| NAKAMURA, T | 1 |
| SHIRAKAWA, S | 1 |
| ADACHI, A | 1 |
| SAKURAI, M | 1 |
| MIYAMOTO, K | 1 |
| KOISO, K | 1 |
| SAKAI, S | 1 |
| SAITO, G | 1 |
| SUGAYAMA, J | 1 |
| KAMASUKA, T | 1 |
| TAKANO, T | 1 |
| TAKADA, S | 1 |
| EVANS, JS | 1 |
| BOSTWICK, L | 1 |
| MENGEL, GD | 1 |
| KOSHIURA, R | 1 |
| KOSHIMURA, S | 1 |
| BANDO, Y | 1 |
| DAWSON, PJ | 1 |
| FIELDSTEEL, AH | 1 |
| BOSTICK, WL | 1 |
| Chen, J | 1 |
| Du, D | 1 |
| Yan, F | 1 |
| Ju, HX | 1 |
| Lian, HZ | 1 |
| Nieborowska-Skorska, M | 1 |
| Stoklosa, T | 1 |
| Datta, M | 1 |
| Czechowska, A | 1 |
| Rink, L | 1 |
| Slupianek, A | 1 |
| Koptyra, M | 1 |
| Seferynska, I | 1 |
| Krszyna, K | 1 |
| Blasiak, J | 1 |
| Skorski, T | 1 |
| Imaizumi, M | 1 |
| Tsuchiya, S | 1 |
| Kobayashi, Y | 1 |
| Yamaguchi, Y | 1 |
| Minegishi, M | 1 |
| Tamura, M | 1 |
| Konno, T | 1 |
| Tada, K | 1 |
| Mourelatos, D | 1 |
| Dozi-Vassiliades, J | 1 |
| Tsigalidou-Balla, V | 1 |
| Granitsas, A | 1 |
| Uchida, A | 1 |
| Micksche, M | 1 |
| Böhmer, RM | 1 |
| Konstantinov, SM | 1 |
| Topashka-Ancheva, M | 1 |
| Benner, A | 1 |
| Berger, MR | 1 |
22 other studies available for mitomycin and Leucocythaemia
| Article | Year |
|---|---|
Erythrocarpines A-E, new cytotoxic limonoids from Chisocheton erythrocarpus.
Topics: Animals; Cell Line; Cell Survival; Leukemia; Limonins; Magnetic Resonance Spectroscopy; Meliaceae; M | 2007 |
Intrinsic growth heterogeneity of mouse leukemia cells underlies differential susceptibility to a growth-inhibiting anticancer drug.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Leu | 2021 |
Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents.
Topics: Antineoplastic Agents; Cell Enlargement; Cell Nucleus; Cytarabine; Cytochalasin B; Doxorubicin; Drug | 2015 |
Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells.
Topics: Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; H | 2010 |
Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells.
Topics: Antibodies; Biological Transport; Buffers; Carrier Proteins; Cell Line, Tumor; Folate Receptors, GPI | 2009 |
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.
Topics: Acute Disease; Amino Acid Sequence; Cell Line, Tumor; Cell Nucleus; DNA Damage; eIF-2 Kinase; Humans | 2011 |
Antibiotics in the control of Hodgkin's disease and the leukemias.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Azaserine; Dactinomycin; Hodgkin Disease; Humans | 1962 |
CHEMOTHERAPY OF LEUKEMIA AND ALLIED DISEASES, WITH SPECIAL REFERENCE TO MYTOMYCIN C.
Topics: Blood; Bone Marrow; Hodgkin Disease; Humans; Leukemia; Leukemia, Myeloid; Mitomycin; Neoplasms | 1964 |
CANCER CHEMOTHERAPY (MITOMYCIN-C) FOLLOWED BY BONE MARROW TRANSPLANTATION.
Topics: Bone Marrow Transplantation; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Bronchogenic; Choriocarci | 1964 |
PRESENT STATUS OF LEUKEMIA IN JAPAN WITH SPECIAL REFERENCE TO EPIDEMIOLOGY AND STUDIES ON THE EFFECT OF CHEMOTHERAPY.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Asian People; Busulfan; DNA; DNA, Neoplasm; Epidemio | 1964 |
[STUDIES ON THE NUCLEIC ACID METABOLISM OF HUMAN LEUKEMIC LEUKOCYTES IN VITRO].
Topics: Adenine Nucleotides; Bone Marrow; Cyclophosphamide; DNA; Formates; Guanine Nucleotides; Humans; In V | 1964 |
ANTICANCER EFFECT OF POLYSACCHARIDE FRACTION PREPARED FROM BAMBOO GRASS.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Japan; Leukemia; Leukemia Virus, Murine; L | 1964 |
SYNERGISM OF THE ANTINEOPLASTIC ACTIVITY OF CYTOSINE ARABINOSIDE BY PORFIROMYCIN.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Cytarabine; Cytosine; Leukemia; | 1964 |
[EXPERIMENTAL ANTICANCER STUDIES. 23. FURTHER EXPERIMENTS ON THE ANTITUMOR ACTIVITY OF 4-AMINO-6-OCTYLRESORCINOL HYDROCHLORIDE].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Leukemia; Leuke | 1964 |
EFFECT OF DRUGS ON CELL AND VIRUS GROWTH IN FRIEND LEUKEMIA AND A TUMOR VARIANT.
Topics: Animals; Estradiol; Friends; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma, Lar | 1965 |
Electrochemical antitumor drug sensitivity test for leukemia K562 cells at a carbon-nanotube-modified electrode.
Topics: Antineoplastic Agents; Doxorubicin; Drug Screening Assays, Antitumor; Electrochemistry; Fluorouracil | 2005 |
ATR-Chk1 axis protects BCR/ABL leukemia cells from the lethal effect of DNA double-strand breaks.
Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Checkpoint Kinas | 2006 |
An Ia-like antigen positive null cell leukemia cell line (THP-5) lacking in the stimulating capacity in autologous and allogeneic mixed lymphocyte reaction.
Topics: Adolescent; Cell Line; Female; Histocompatibility Antigens Class II; Humans; Leukemia; Lymphocyte Ac | 1984 |
Enhancement by methylxanthines of sister-chromatid exchange frequency induced by cytostatics in normal and leukemic human lymphocytes.
Topics: Caffeine; Cells, Cultured; Crossing Over, Genetic; Cytarabine; Drug Synergism; Humans; Leukemia; Lym | 1983 |
Lysis of fresh human tumor cells by autologous peripheral blood lymphocytes and pleural effusion lymphocytes activated by OK432.
Topics: Adenocarcinoma; Adult; Aged; Biological Products; Cytotoxicity, Immunologic; Dactinomycin; Female; H | 1983 |
Two-step cell-death kinetics in vitro during cis-platinum, hydroxyurea and mitomycin incubation.
Topics: Antibiotics, Antineoplastic; Cell Line; Cell Survival; Cisplatin; Flow Cytometry; Humans; Hydroxyure | 1984 |
Alkylphosphocholines: Effects on human leukemic cell lines and normal bone marrow cells.
Topics: Alkylation; Animals; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cell Cycle; Cell Division; | 1998 |