mitomycin has been researched along with Kidney Diseases in 23 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen patients with adenocarcinoma of the gastrointestinal tract and pancreas treated with mitomycin C(MMC) and 5-fluorouracil (5-FU) had renal impairment 6-11 months from the beginning of MMC therapy." | 3.66 | Renal disease after mitomycin C therapy. ( Hanna, WT; Krauss, S; Murphy, WM; Regester, RF, 1981) |
| "Three women with adenocarcinoma of cardia, adenocarcinoma of liver or ileum carcinoid tumor, respectively, were treated with mitomycin C (MMC) and 5-fluoro-uracil (5-FU)." | 3.66 | [Mytomycin C nephrotoxicity. 3 new cases and review of the literature]. ( Ang, KS; Cledes, J; Hervé, JP; Leguy, P; Leroy, JP; Ramée, MP; Simon, P; Vignoud, J, 1982) |
| "Hyporeninemic hypoaldosteronism was transiently seen in case 2." | 1.29 | Long-term follow-up of mitomycin C nephropathy. ( Ikeda, K; Motoo, Y; Ohta, H; Okai, T; Sawabu, N; Takemori, Y; Yokoyama, H, 1994) |
| "Mitomycin C (MMC) has been known to be nephrotoxic since 1971." | 1.27 | Mitomycin C-induced renal toxicity, a dose-dependent side effect? ( de Vries, J; Pinedo, HM; Verwey, J, 1987) |
| "The mitomycin C dose was less than or equal to 15 mg/m2 every 53rd day and the total cumulative dose was between 25 and 250 mg." | 1.27 | Renal complications of mitomycin C therapy with special reference to the total dose. ( Nordman, E; Valavaara, R, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (56.52) | 18.7374 |
| 1990's | 8 (34.78) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsui, Y | 1 |
| Sunatani, Y | 1 |
| Hayashi, N | 1 |
| Okino, K | 1 |
| Okushi, Y | 1 |
| Mukai, K | 1 |
| Adachi, H | 1 |
| Yamaya, H | 1 |
| Iwabuchi, K | 1 |
| Yokoyama, H | 2 |
| Wen, MC | 1 |
| Chen, CH | 1 |
| Ho, WL | 1 |
| Bukowski, RM | 1 |
| Balcerzak, SP | 1 |
| O'Bryan, RM | 1 |
| Bonnet, JD | 1 |
| Chen, TT | 1 |
| Cordonnier, D | 1 |
| Alix, JL | 1 |
| Schaerer, R | 1 |
| Swiercz, P | 1 |
| Vialtel, P | 1 |
| Bayle, F | 1 |
| Fillastre, JP | 1 |
| Méry, JP | 1 |
| Druet, P | 1 |
| Yamada, F | 1 |
| Kagami, H | 1 |
| Fukutome, A | 1 |
| Mastumine, T | 1 |
| Miura, T | 1 |
| Dumler, F | 1 |
| Ravikumar, TS | 1 |
| Sibley, R | 1 |
| Reed, K | 1 |
| Grage, TB | 1 |
| Hanna, WT | 1 |
| Krauss, S | 1 |
| Regester, RF | 1 |
| Murphy, WM | 1 |
| Kreusser, W | 1 |
| Herrmann, R | 1 |
| Tschöpe, W | 1 |
| Ritz, E | 1 |
| Simon, P | 1 |
| Hervé, JP | 1 |
| Ramée, MP | 1 |
| Leroy, JP | 1 |
| Ang, KS | 1 |
| Leguy, P | 1 |
| Vignoud, J | 1 |
| Cledes, J | 1 |
| Nakabayashi, K | 1 |
| Gao, Y | 1 |
| Shimizu, M | 1 |
| Yamada, S | 1 |
| Ozaki, Y | 1 |
| Aso, T | 1 |
| Motoo, Y | 1 |
| Sawabu, N | 1 |
| Ikeda, K | 1 |
| Takemori, Y | 1 |
| Ohta, H | 1 |
| Okai, T | 1 |
| Cachat, F | 1 |
| Guignard, JP | 1 |
| Nakahama, H | 1 |
| Lee, YK | 1 |
| Shin, DM | 1 |
| Shiiki, H | 1 |
| Dohi, K | 1 |
| Nishioka, H | 1 |
| Matsuda, T | 1 |
| Kanauchi, M | 1 |
| Uyama, H | 1 |
| Ishikawa, H | 1 |
| Watanabe, T | 1 |
| Vogelzang, NJ | 1 |
| Omata, M | 1 |
| Kikuchi, M | 1 |
| Higuchi, C | 1 |
| Sanaka, S | 1 |
| Takuma, T | 1 |
| Sugino, N | 1 |
| Mori, Y | 1 |
| Verweij, J | 1 |
| Stoter, G | 1 |
| Verwey, J | 1 |
| de Vries, J | 1 |
| Pinedo, HM | 1 |
| Valavaara, R | 1 |
| Nordman, E | 1 |
7 reviews available for mitomycin and Kidney Diseases
| Article | Year |
|---|---|
[Drug-induced glomerular nephropathies].
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Daunorubicin; Disease Models, Animal; Doxorubici | 1983 |
Nephrological complications of cancer therapy.
Topics: Acute Kidney Injury; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Humans; Ifosfamide; Kidney; | 1982 |
[Kidney disorders caused by antineoplastic agents].
Topics: Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Kidney Diseases; Methotrexate; Mitomycin; Nimustin | 1994 |
[The kidney in children under chemotherapy].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Child; Cisplatin; Glomerular | 1996 |
[Nephrotoxicity of antineoplastic agents (antibiotics)].
Topics: Antibiotics, Antineoplastic; Doxorubicin; Humans; Kidney Diseases; Mitomycin; Plicamycin | 1997 |
Nephrotoxicity from chemotherapy: prevention and management.
Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Gallium; Humans; Ifosfamide; Kidney Diseases; Methotr | 1991 |
Severe side effects of the cytotoxic drug mitomycin-C.
Topics: Animals; Heart Failure; Hepatic Veno-Occlusive Disease; Humans; Kidney Diseases; Mitomycin; Mitomyci | 1987 |
1 trial available for mitomycin and Kidney Diseases
| Article | Year |
|---|---|
Randomized trial of 5-fluorouracil and mitomycin C with or without streptozotocin for advanced pancreatic cancer. A Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Therapy, | 1983 |
15 other studies available for mitomycin and Kidney Diseases
| Article | Year |
|---|---|
DNA double-strand breaks induced intractable glomerular fibrosis in renal allografts.
Topics: Adult; Aged; Allografts; Capillaries; Cells, Cultured; Collagen; DNA Breaks, Double-Stranded; Female | 2016 |
Mitomycin C-induced renal insufficiency: a case report.
Topics: Anemia, Hemolytic; Antibiotics, Antineoplastic; Humans; Hypertension; Kidney Diseases; Male; Middle | 2003 |
[Nephrotoxicity of antitumor chemotherapy].
Topics: Antineoplastic Agents; Cisplatin; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Human | 1984 |
[Experience of a combination chemotherapy consisting of 5-FU, MMC, and FT-207--side effects against kidney].
Topics: Aged; Drug Therapy, Combination; Fluorouracil; Humans; Kidney Diseases; Male; Mitomycin; Mitomycins; | 1983 |
Drug-induced glomerulopathy: a selective review.
Topics: Anti-Inflammatory Agents; Captopril; Child; Gold; Humans; Kidney Diseases; Mitomycin; Mitomycins; Pe | 1983 |
Renal toxicity of mitomycin-C.
Topics: Adult; Aged; Anemia, Hemolytic; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; K | 1984 |
Renal disease after mitomycin C therapy.
Topics: Acute Kidney Injury; Adenocarcinoma; Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Creatinine; F | 1981 |
[Mytomycin C nephrotoxicity. 3 new cases and review of the literature].
Topics: Adenocarcinoma; Carcinoid Tumor; Creatinine; Female; Gastrointestinal Neoplasms; Humans; Kidney Dise | 1982 |
The effects of chemotherapy including cisplatin on vitamin D metabolism.
Topics: 24,25-Dihydroxyvitamin D 3; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Adult; Antineoplastic Combined | 1993 |
Long-term follow-up of mitomycin C nephropathy.
Topics: Hemolytic-Uremic Syndrome; Humans; Hypoaldosteronism; Kidney Diseases; Male; Microscopy, Electron; M | 1994 |
Renal salt wasting in patients treated with high-dose cisplatin, etoposide, and mitomycin in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat | 1992 |
Glomerular tuft ballooning in mitomycin-C-induced renal impairment.
Topics: Aged; Biopsy; Capillaries; Humans; Kidney Diseases; Kidney Glomerulus; Male; Microscopy, Electron; M | 1992 |
Drug-induced nephropathy: our recent clinical experience.
Topics: Adult; Aged; Carbon Tetrachloride; Female; Germanium; Hemolytic-Uremic Syndrome; Humans; Kidney Dise | 1986 |
Mitomycin C-induced renal toxicity, a dose-dependent side effect?
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Hemolysis; Hemolytic-Uremic Syndrome; Humans; | 1987 |
Renal complications of mitomycin C therapy with special reference to the total dose.
Topics: Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Female; | 1985 |