Page last updated: 2024-11-06

mitomycin and Keratoconus

mitomycin has been researched along with Keratoconus in 6 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Keratoconus: A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To evaluate and compare corneal haze as determined by optical coherence tomography (OCT) after corneal cross-linking (CXL) for the treatment of mild to moderate keratoconus with or without mitomycin C (MMC) application."8.02Mitomycin C Application After Corneal Cross-linking for Keratoconus Increases Stromal Haze. ( Abdul Fattah, M; Awwad, ST; Chacra, LM; Dhaini, AR; Hafezi, F; Helwe, C; Shetty, R; Telvizian, T; Torbey, J; Torres-Netto, EA, 2021)
"To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus."7.88Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus. ( Li, Z; Mu, G; Pu, W; Tao, X; Xie, Y; Xu, H; Xu, L; Xu, Y; Zhu, W, 2018)
"Consecutive patients who had PRK augmented with topical mitomycin-C (MMC) after PKP for keratoconus were retrospectively reviewed."7.77Photorefractive keratectomy with mitomycin-C after corneal transplantation for keratoconus. ( Hodge, C; Lawless, M; Rogers, C; Sutton, G, 2011)
"To report topography-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) after penetrating keratoplasty for keratoconus."7.75Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report. ( Alves, MR; Barreto, J; Bechara, SJ; Nakano, M; Netto, MV; Reis, A, 2009)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with intraoperative mitomycin C (MMC) after deep anterior lamellar keratoplasty (DALK) for keratoconus."7.74Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus. ( Leccisotti, A, 2008)
"To present a case of photorefractive keratectomy (PRK) with adjunctive topical mitomycin C (MMC) in an anisometropic hyperopic patient after penetrating keratoplasty (PKP) for keratoconus."7.72Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus. ( Donnenfeld, ED; Perry, HD; Solomon, R; Stein, J; Thimons, J, 2004)
"To evaluate and compare corneal haze as determined by optical coherence tomography (OCT) after corneal cross-linking (CXL) for the treatment of mild to moderate keratoconus with or without mitomycin C (MMC) application."4.02Mitomycin C Application After Corneal Cross-linking for Keratoconus Increases Stromal Haze. ( Abdul Fattah, M; Awwad, ST; Chacra, LM; Dhaini, AR; Hafezi, F; Helwe, C; Shetty, R; Telvizian, T; Torbey, J; Torres-Netto, EA, 2021)
"To evaluate the safety and efficacy of mitomycin C (MMC) in haze formation after ultraviolet A/riboflavin corneal crosslinking (CXL) for progressive keratoconus."3.88Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus. ( Li, Z; Mu, G; Pu, W; Tao, X; Xie, Y; Xu, H; Xu, L; Xu, Y; Zhu, W, 2018)
"To report topography-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) after penetrating keratoplasty for keratoconus."3.75Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report. ( Alves, MR; Barreto, J; Bechara, SJ; Nakano, M; Netto, MV; Reis, A, 2009)
"To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with intraoperative mitomycin C (MMC) after deep anterior lamellar keratoplasty (DALK) for keratoconus."3.74Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus. ( Leccisotti, A, 2008)
"To present a case of photorefractive keratectomy (PRK) with adjunctive topical mitomycin C (MMC) in an anisometropic hyperopic patient after penetrating keratoplasty (PKP) for keratoconus."3.72Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus. ( Donnenfeld, ED; Perry, HD; Solomon, R; Stein, J; Thimons, J, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Awwad, ST1
Chacra, LM1
Helwe, C1
Dhaini, AR1
Telvizian, T1
Torbey, J1
Abdul Fattah, M1
Torres-Netto, EA1
Hafezi, F1
Shetty, R1
Xu, L1
Tao, X1
Li, Z1
Xu, Y1
Zhu, W1
Xu, H1
Pu, W1
Xie, Y1
Mu, G1
Barreto, J1
Netto, MV1
Reis, A1
Nakano, M1
Alves, MR1
Bechara, SJ1
Hodge, C1
Sutton, G1
Lawless, M1
Rogers, C1
Solomon, R1
Donnenfeld, ED1
Thimons, J1
Stein, J1
Perry, HD1
Leccisotti, A1

Other Studies

6 other studies available for mitomycin and Keratoconus

ArticleYear
Mitomycin C Application After Corneal Cross-linking for Keratoconus Increases Stromal Haze.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2021, Feb-01, Volume: 37, Issue:2

    Topics: Corneal Topography; Cross-Linking Reagents; Humans; Keratoconus; Mitomycin; Photochemotherapy; Photo

2021
Clinical Study of Mitomycin C in Reducing Haze Formation After Ultraviolet A/Riboflavin Crosslinking for Keratoconus.
    Eye & contact lens, 2018, Volume: 44 Suppl 2

    Topics: Adolescent; Adult; Corneal Opacity; Cross-Linking Reagents; Female; Humans; Keratoconus; Male; Mitom

2018
Topography-guided (NIDEK customized aspheric treatment zone) photorefractive keratectomy with mitomycin C after penetrating keratoplasty for keratoconus: case report.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2009, Volume: 25, Issue:1 Suppl

    Topics: Adult; Alkylating Agents; Astigmatism; Combined Modality Therapy; Corneal Topography; Female; Humans

2009
Photorefractive keratectomy with mitomycin-C after corneal transplantation for keratoconus.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:10

    Topics: Adult; Aged; Alkylating Agents; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Kerato

2011
Hyperopic photorefractive keratectomy with adjunctive topical mitomycin C for refractive error after penetrating keratoplasty for keratoconus.
    Eye & contact lens, 2004, Volume: 30, Issue:3

    Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Corneal Opacity

2004
Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus.
    Cornea, 2008, Volume: 27, Issue:4

    Topics: Adult; Alkylating Agents; Astigmatism; Cell Count; Combined Modality Therapy; Corneal Topography; Co

2008