mitomycin has been researched along with Keloid in 15 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of mitomycin C in reducing keloid recurrence." | 10.25 | Role of mitomycin C in reducing keloid recurrence: patient series and literature review. ( Gupta, M; Narang, T, 2011) |
| "To determine the effects of topical mitomycin C (MC) on shave-removed wounds and fibroblasts of ear keloids." | 9.15 | Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study. ( Chi, SG; Kim, BS; Kim, DW; Kim, GW; Kim, JY; Kim, MB; Lee, SJ; Lee, WJ; Sohn, MY, 2011) |
| "Mitomycin C (MMC) is an antineoplastic antibiotic that has been used off-label in the treatment of hypertrophic scars and keloids." | 8.89 | Mitomycin C in the treatment of keloids: a case and review. ( Chotzen, VA; Kilmer, SL; Kleinerman, R, 2013) |
| "To investigate the efficacy of topical and intralesional mitomycin C for the treatment of keloids and HTS." | 7.78 | Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C. ( Seo, SH; Sung, HW, 2012) |
| "To determine whether application of mitomycin C to the base of shave-removed keloids would prevent their recurrence." | 7.74 | Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence. ( Bailey, JN; Clayton, WJ; Rustin, MH; Waite, AE, 2007) |
| "To study the role of mitomycin C in reducing keloid recurrence." | 6.25 | Role of mitomycin C in reducing keloid recurrence: patient series and literature review. ( Gupta, M; Narang, T, 2011) |
| "Mitomycin C (MC) is an anti-neoplastic agent with an anti-proliferative effect on fibroblasts." | 5.33 | Use of mitomycin C for treatment of keloid: a preliminary report. ( Kronenberg, J; Orenstein, A; Talmi, YP; Wolf, M, 2005) |
| "Mitomycin-C is a chemotherapeutic agent that inhibits DNA synthesis and fibroblast proliferation." | 5.33 | Application of mitomycin-C for head and neck keloids. ( Kim, JY; Stewart, CE, 2006) |
| "Keloids are the result of aberrant wound healing of human skin after dermal injury." | 5.32 | Effect of mitomycin C on keloid fibroblasts: an in vitro study. ( Alani, H; Simman, R; Williams, F, 2003) |
| "To determine the effects of topical mitomycin C (MC) on shave-removed wounds and fibroblasts of ear keloids." | 5.15 | Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study. ( Chi, SG; Kim, BS; Kim, DW; Kim, GW; Kim, JY; Kim, MB; Lee, SJ; Lee, WJ; Sohn, MY, 2011) |
| " The predictor variables were mitomycin C (MC) and imiquimod cream treatment after keloid excision." | 4.95 | Efficacy of 2 Representative Topical Agents to Prevent Keloid Recurrence After Surgical Excision. ( Lee, NH; Roh, SG; Shin, JY; Yang, KM; Yun, SK, 2017) |
| "Mitomycin C (MMC) is an antineoplastic antibiotic that has been used off-label in the treatment of hypertrophic scars and keloids." | 4.89 | Mitomycin C in the treatment of keloids: a case and review. ( Chotzen, VA; Kilmer, SL; Kleinerman, R, 2013) |
| "To investigate the efficacy of topical and intralesional mitomycin C for the treatment of keloids and HTS." | 3.78 | Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C. ( Seo, SH; Sung, HW, 2012) |
| "To determine whether application of mitomycin C to the base of shave-removed keloids would prevent their recurrence." | 3.74 | Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence. ( Bailey, JN; Clayton, WJ; Rustin, MH; Waite, AE, 2007) |
| "Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar." | 2.46 | The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review. ( Basdag, B; Magarakis, M; Manson, PN; Rosson, GD; Shridharani, SM; Singh, NK, 2010) |
| "Keloids are special type of skin lesions arising from sites of previous trauma." | 2.43 | [Therapeutic problems connected with keloid treatment--new treatment possibilities]. ( Brudnik, U; Podolec-Rubiś, M; Wojas-Pelc, A, 2006) |
| "Mitomycin C (MC) is an anti-neoplastic agent with an anti-proliferative effect on fibroblasts." | 1.33 | Use of mitomycin C for treatment of keloid: a preliminary report. ( Kronenberg, J; Orenstein, A; Talmi, YP; Wolf, M, 2005) |
| "Mitomycin-C is a chemotherapeutic agent that inhibits DNA synthesis and fibroblast proliferation." | 1.33 | Application of mitomycin-C for head and neck keloids. ( Kim, JY; Stewart, CE, 2006) |
| "Keloids are the result of aberrant wound healing of human skin after dermal injury." | 1.32 | Effect of mitomycin C on keloid fibroblasts: an in vitro study. ( Alani, H; Simman, R; Williams, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleinerman, R | 1 |
| Kilmer, SL | 1 |
| Chotzen, VA | 1 |
| Willett, M | 1 |
| Handfield, K | 1 |
| Marquart, J | 1 |
| Shin, JY | 1 |
| Yun, SK | 1 |
| Roh, SG | 1 |
| Lee, NH | 1 |
| Yang, KM | 1 |
| Wang, XQ | 2 |
| Liu, YK | 2 |
| Wang, ZY | 1 |
| Jiang, YZ | 1 |
| Lu, SL | 2 |
| Qing, C | 1 |
| Shridharani, SM | 1 |
| Magarakis, M | 1 |
| Manson, PN | 1 |
| Singh, NK | 1 |
| Basdag, B | 1 |
| Rosson, GD | 1 |
| Gupta, M | 1 |
| Narang, T | 1 |
| Chi, SG | 1 |
| Kim, JY | 2 |
| Lee, WJ | 1 |
| Lee, SJ | 1 |
| Kim, DW | 1 |
| Sohn, MY | 1 |
| Kim, GW | 1 |
| Kim, MB | 1 |
| Kim, BS | 1 |
| Seo, SH | 1 |
| Sung, HW | 1 |
| Cupp, C | 1 |
| Gaball, CW | 1 |
| Simman, R | 1 |
| Alani, H | 1 |
| Williams, F | 1 |
| Talmi, YP | 1 |
| Orenstein, A | 1 |
| Wolf, M | 1 |
| Kronenberg, J | 1 |
| Stewart, CE | 1 |
| Bailey, JN | 1 |
| Waite, AE | 1 |
| Clayton, WJ | 1 |
| Rustin, MH | 1 |
| Brudnik, U | 1 |
| Podolec-Rubiś, M | 1 |
| Wojas-Pelc, A | 1 |
7 reviews available for mitomycin and Keloid
| Article | Year |
|---|---|
Mitomycin C in the treatment of keloids: a case and review.
Topics: Adult; Alkylating Agents; Female; Follow-Up Studies; Humans; Keloid; Mitomycin; Off-Label Use | 2013 |
Efficacy of 2 Representative Topical Agents to Prevent Keloid Recurrence After Surgical Excision.
Topics: Administration, Cutaneous; Aminoquinolines; Dermatologic Agents; Humans; Imiquimod; Keloid; Mitomyci | 2017 |
Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antimitotic A | 2008 |
A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bleomycin; Cicatrix, Hypertrophic; Colchicine; Drug Ther | 2009 |
The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review.
Topics: Antineoplastic Agents; Bleomycin; Cicatrix; Fluorouracil; Humans; Hypertrophy; Interferon-alpha; Kel | 2010 |
Role of mitomycin C in reducing keloid recurrence: patient series and literature review.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Ear Auricle; Female; Humans; Keloid; Middle Aged; Mi | 2011 |
[Therapeutic problems connected with keloid treatment--new treatment possibilities].
Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Fibroblasts; Humans; Keloid; Mitomycin; Scleroderma, Lo | 2006 |
2 trials available for mitomycin and Keloid
| Article | Year |
|---|---|
Role of mitomycin C in reducing keloid recurrence: patient series and literature review.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Ear Auricle; Female; Humans; Keloid; Middle Aged; Mi | 2011 |
Ear keloids as a primary candidate for the application of mitomycin C after shave excision: in vivo and in vitro study.
Topics: Adolescent; Adult; Body Piercing; Cell Culture Techniques; Ear, External; Female; Fibroblasts; Human | 2011 |
7 other studies available for mitomycin and Keloid
| Article | Year |
|---|---|
Multimodal keloid therapy with excision, application of mitomycin C, and radiotherapy.
Topics: Adult; Antibiotics, Antineoplastic; Chemoradiotherapy, Adjuvant; Dose Fractionation, Radiation; Fema | 2014 |
Treatment of keloids and hypertrophic scars using topical and intralesional mitomycin C.
Topics: Administration, Topical; Adolescent; Adult; Aged; Cicatrix, Hypertrophic; Female; Humans; Injections | 2012 |
Utilizing topical therapies and mitomycin to reduce scars.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Child; Cicatrix, Hypertrophic; Dermatologic Surgical | 2012 |
Effect of mitomycin C on keloid fibroblasts: an in vitro study.
Topics: Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA; Fibroblasts; | 2003 |
Use of mitomycin C for treatment of keloid: a preliminary report.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; F | 2005 |
Application of mitomycin-C for head and neck keloids.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Black or African American; Combined Modality Therapy | 2006 |
Application of topical mitomycin C to the base of shave-removed keloid scars to prevent their recurrence.
Topics: Adult; Female; Glycopeptides; Humans; Keloid; Male; Middle Aged; Mitomycin; Nucleic Acid Synthesis I | 2007 |