mitomycin has been researched along with Kaposi Disease in 26 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Crosslink repair of mitomycin C-induced interstrand crosslinks was studied in exponentially growing and confluent normal human, transformed W138CT-1, Fanconi's anemia (FA) and xeroderma pigmentosum (XP) group-A fibroblasts by the assay methods of alkaline sucrose centrifugation, hydroxyapatite column chromatography and S1-nuclease digestion." | 7.66 | Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells. ( Fujiwara, Y, 1982) |
| " No discernible difference could be detected between the fluence-response curves of pyrimidine dimers for untreated and MMC-treated repair-deficient xeroderma pigmentosum cells of group A." | 3.67 | Mitomycin C-induced postmitotic fibroblasts retain the capacity to repair pyrimidine photodimers formed after UV-irradiation. ( Bayreuther, K; Francz, PI; Niggli, HJ; Rodemann, HP; Röthlisberger, R, 1989) |
| "Cycloheximide strongly antagonizes the induction of sister-chromatid exchanges by ethyl methanesulfonate or mitomycin C in human skin fibroblast and xeroderma pigmentosum cells (group A)." | 3.67 | Inhibition of protein synthesis does not antagonize induction of UV-induced sister-chromatid exchange in xeroderma pigmentosum cells. ( Sakaguchi, K; Sono, A, 1988) |
| "Crosslink repair of mitomycin C-induced interstrand crosslinks was studied in exponentially growing and confluent normal human, transformed W138CT-1, Fanconi's anemia (FA) and xeroderma pigmentosum (XP) group-A fibroblasts by the assay methods of alkaline sucrose centrifugation, hydroxyapatite column chromatography and S1-nuclease digestion." | 3.66 | Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells. ( Fujiwara, Y, 1982) |
| "Xeroderma pigmentosum is a rare genetic disorder associated with various ocular malignancies." | 2.53 | Xeroderma pigmentosum with bilateral ocular surface squamous neoplasia and review of the literature. ( Kalamkar, C; Mukherjee, A; Radke, N; Radke, S, 2016) |
| "The frequency of SCEs and chromosome aberrations induced by mitomycin C (MMC) or UV was enhanced by the posttreatment with tea tannin components." | 1.28 | Tea tannin components modify the induction of sister-chromatid exchanges and chromosome aberrations in mutagen-treated cultured mammalian cells and mice. ( Imanishi, H; Kato, T; Ohta, T; Sasaki, YF; Shirasu, Y; Watanabe, M, 1991) |
| "In order to develop the usefulness of Fanconi's anemia (FA) lymphoblast lines for biochemical and genetic studies, we have determined their sensitivity to a variety of DNA-damaging chemicals." | 1.26 | Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. ( Buchwald, M; Ishida, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Dirar, QS | 1 |
| Musalem, HM | 1 |
| Al-Hazzaa, SAF | 1 |
| Al Zoba, AA | 1 |
| Almalki, AA | 1 |
| Yuksel, D | 1 |
| Kosker, M | 1 |
| Reddy, JC | 1 |
| Celik, T | 1 |
| El Hamichi, S | 1 |
| Messaoudi, R | 1 |
| Belmalih, M | 1 |
| Iferkhass, S | 1 |
| Zerrouk, R | 1 |
| Reda, K | 1 |
| Oubaaz, A | 1 |
| Hashimoto, K | 1 |
| Wada, K | 1 |
| Matsumoto, K | 2 |
| Moriya, M | 1 |
| Kalamkar, C | 1 |
| Radke, N | 1 |
| Mukherjee, A | 1 |
| Radke, S | 1 |
| Abdel-Halim, HI | 1 |
| Natarajan, AT | 1 |
| Mullenders, LH | 1 |
| Boei, JJ | 1 |
| Cohen, MM | 1 |
| Fruchtman, CE | 1 |
| Simpson, SJ | 1 |
| Martin, AO | 1 |
| Nagasawa, H | 1 |
| Little, FF | 1 |
| Burke, MJ | 1 |
| McCone, EF | 1 |
| Targovnik, HS | 1 |
| Chan, GL | 1 |
| Little, JB | 1 |
| Fujiwara, Y | 2 |
| Kano, Y | 1 |
| Yamamoto, Y | 1 |
| Ishida, R | 1 |
| Buchwald, M | 1 |
| Liu, P | 1 |
| Siciliano, J | 1 |
| White, B | 1 |
| Legerski, R | 2 |
| Callen, D | 1 |
| Reeders, S | 1 |
| Siciliano, MJ | 2 |
| Thompson, LH | 2 |
| Sijbers, AM | 1 |
| van der Spek, PJ | 1 |
| Odijk, H | 1 |
| van den Berg, J | 1 |
| van Duin, M | 1 |
| Westerveld, A | 1 |
| Jaspers, NG | 1 |
| Bootsma, D | 1 |
| Hoeijmakers, JH | 1 |
| Yagi, T | 1 |
| Katsuya, A | 1 |
| Koyano, A | 1 |
| Takebe, H | 1 |
| Raderschall, E | 1 |
| Golub, EI | 1 |
| Haaf, T | 1 |
| Speit, G | 1 |
| Schütz, P | 1 |
| Merk, O | 1 |
| Zhang, N | 1 |
| Zhang, X | 1 |
| Peterson, C | 1 |
| Li, L | 1 |
| Nocentini, S | 1 |
| Imanishi, H | 2 |
| Sasaki, YF | 2 |
| Ohta, T | 1 |
| Watanabe, M | 1 |
| Kato, T | 1 |
| Shirasu, Y | 2 |
| Shimoi, K | 1 |
| Nakamura, Y | 1 |
| Noro, T | 1 |
| Tomita, I | 1 |
| Niggli, HJ | 1 |
| Bayreuther, K | 1 |
| Rodemann, HP | 1 |
| Röthlisberger, R | 1 |
| Francz, PI | 1 |
| Sono, A | 1 |
| Sakaguchi, K | 1 |
| Andriadze, MI | 1 |
| Pleskach, NM | 1 |
| Mikhel'son, VM | 1 |
| Zhestianikov, VD | 1 |
| Protić, M | 1 |
| Roilides, E | 1 |
| Levine, AS | 1 |
| Dixon, K | 1 |
| Mooney, CL | 1 |
| Burkhart-Schultz, K | 1 |
| Carrano, AV | 1 |
| Plooy, AC | 1 |
| van Dijk, M | 1 |
| Berends, F | 1 |
| Lohman, PH | 1 |
1 review available for mitomycin and Kaposi Disease
| Article | Year |
|---|---|
Xeroderma pigmentosum with bilateral ocular surface squamous neoplasia and review of the literature.
Topics: Administration, Topical; Carcinoma, Squamous Cell; Child; Cytoreduction Surgical Procedures; Eye Neo | 2016 |
25 other studies available for mitomycin and Kaposi Disease
| Article | Year |
|---|---|
Effect of Pegylated Interferon and Mitomycin C on Ocular Surface Squamous Neoplasia in Xeroderma Pigmentosum: A Case Series.
Topics: Adult; Antibiotics, Antineoplastic; Antiviral Agents; Carcinoma, Squamous Cell; Drug Therapy, Combin | 2020 |
Management of cataracts and oculo-cutaneous malignancy in xeroderma pigmentosum.
Topics: Adolescent; Biological Dressings; Carcinoma, Squamous Cell; Cataract; Conjunctival Neoplasms; Female | 2013 |
Bilateral enucleation avoided by excision with mitomycin C for bilateral infiltrating conjunctival squamous cell carcinoma in a girl with xeroderma pigmentosum.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Child; Combined Modality Therapy; Conjunctival Neop | 2015 |
Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations.
Topics: Amino Acid Sequence; Animals; Chromosome Aberrations; Cockayne Syndrome; DNA Repair; DNA-Binding Pro | 2015 |
Mitomycin C-induced pairing of heterochromatin reflects initiation of DNA repair and chromatid exchange formation.
Topics: Cells, Cultured; Chromosome Pairing; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Cross-L | 2005 |
The cytogenetic response of Fanconi's anemia lymphoblastoid cell lines to various clastogens.
Topics: Adult; Anemia, Aplastic; Ataxia Telangiectasia; Bleomycin; Cell Line; Child; Child, Preschool; Epoxy | 1982 |
Study of basal cell nevus syndrome fibroblasts after treatment with DNA-damaging agents.
Topics: Adolescent; Adult; Ataxia Telangiectasia; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Child; D | 1984 |
DNA interstrand cross-linking, repair, and SCE mechanism in human cells in special reference to Fanconi anemia.
Topics: Anemia, Aplastic; Cell Survival; Cells, Cultured; Cross-Linking Reagents; DNA Repair; DNA Replicatio | 1984 |
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Anemia, Aplastic; Antibiotics, Antineoplastic; Carcinog | 1982 |
Defective repair of mitomycin C crosslinks in Fanconi's anemia and loss in confluent normal human and xeroderma pigmentosum cells.
Topics: Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Cycle; DNA; DNA Repair; Fanconi Anemia; Fibrobla | 1982 |
Regional mapping of human DNA excision repair gene ERCC4 to chromosome 16p13.13-p13.2.
Topics: Animals; Cell Line; Cell Survival; CHO Cells; Chromosome Mapping; Chromosomes, Human, Pair 16; Cosmi | 1993 |
Mutational analysis of the human nucleotide excision repair gene ERCC1.
Topics: Amino Acid Sequence; Animals; Cisplatin; Conserved Sequence; DNA Mutational Analysis; DNA Repair; DN | 1996 |
Sensitivity of group F xeroderma pigmentosum cells to UV and mitomycin C relative to levels of XPF and ERCC1 overexpression.
Topics: Clone Cells; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Humans; Mitomycin; Nucleic Aci | 1998 |
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage.
Topics: Animals; Cell Cycle; Cell Line; Cell Nucleus; Chromatin; Cycloheximide; Dactinomycin; DNA Damage; DN | 1999 |
Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.
Topics: Cell Line; Cross-Linking Reagents; DNA; DNA Repair; Fanconi Anemia; Formaldehyde; Humans; Micronucle | 2000 |
Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts.
Topics: Animals; Cell Line; Cell Line, Transformed; Cell Survival; Cell-Free System; CHO Cells; Cricetinae; | 2000 |
Cellular responses to hematoporphyrin-induced photooxidative damage in Fanconi anemia, xeroderma pigmentosum and normal human fibroblasts.
Topics: Cell Line; Cell Survival; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Dose-Response | 1992 |
Tea tannin components modify the induction of sister-chromatid exchanges and chromosome aberrations in mutagen-treated cultured mammalian cells and mice.
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Humans; Male; Mice; Micronucleus Tests; Mito | 1991 |
Enhancing effects of cinoxate and methyl sinapate on the frequencies of sister-chromatid exchanges and chromosome aberrations in cultured mammalian cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Chromosome Aberrations; Cinnamates; Cricetinae; DNA Re | 1989 |
Mitomycin C-induced postmitotic fibroblasts retain the capacity to repair pyrimidine photodimers formed after UV-irradiation.
Topics: Cell Differentiation; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Repair; Fibrob | 1989 |
Inhibition of protein synthesis does not antagonize induction of UV-induced sister-chromatid exchange in xeroderma pigmentosum cells.
Topics: Cells, Cultured; Fibroblasts; Humans; Mesylates; Mitomycin; Mitomycins; Mutagens; Sister Chromatid E | 1988 |
[Spontaneous and induced sister chromatid exchanges in the blood lymphocytes of healthy persons and of xeroderma pigmentosum patients exposed to the inhibitors of DNA repair and replication caffeine, 3-methoxybenzamide and novobiocin].
Topics: Adult; Benzamides; Caffeine; Cells, Cultured; DNA Repair; DNA Replication; Ethyl Methanesulfonate; H | 1986 |
Enhancement of DNA repair capacity of mammalian cells by carcinogen treatment.
Topics: Acetyltransferases; Animals; Cell Line; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; D | 1988 |
Correction of a nucleotide-excision-repair mutation by human chromosome 19 in hamster-human hybrid cells.
Topics: Animals; Chromosomes, Human, 19-20; Cricetinae; Cricetulus; DNA Repair; Drug Resistance; Humans; Hyb | 1985 |
Formation and repair of DNA interstrand cross-links in relation to cytotoxicity and unscheduled DNA synthesis induced in control and mutant human cells treated with cis-diamminedichloroplatinum(II).
Topics: Cell Line; Cell Survival; Cisplatin; DNA; DNA Repair; Fanconi Anemia; Humans; Mitomycin; Mitomycins; | 1985 |