Page last updated: 2024-11-06

mitomycin and Intellectual Disability

mitomycin has been researched along with Intellectual Disability in 2 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"Seckel syndrome is a rare autosomal recessive disorder."5.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)
"Seckel syndrome is a rare autosomal recessive disorder."1.30Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. ( Abou-Zahr, F; Bacino, C; Bejjani, B; Kruyt, FA; Kurg, R; Shapira, SK; Youssoufian, H, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bobabilla-Morales, L1
Corona-Rivera, A1
Corona-Rivera, JR1
Buenrostro, C1
García-Cobián, TA1
Corona-Rivera, E1
Cantú-Garza, JM1
García-Cruz, D1
Abou-Zahr, F1
Bejjani, B1
Kruyt, FA1
Kurg, R1
Bacino, C1
Shapira, SK1
Youssoufian, H1

Other Studies

2 other studies available for mitomycin and Intellectual Disability

ArticleYear
Chromosome instability induced in vitro with mitomycin C in five Seckel syndrome patients.
    American journal of medical genetics. Part A, 2003, Dec-01, Volume: 123A, Issue:2

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child, Preschool; Chromosomal Instability; Cytogenetic A

2003
Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome.
    American journal of medical genetics, 1999, Apr-23, Volume: 83, Issue:5

    Topics: Abnormalities, Multiple; Blotting, Western; Cell Cycle Proteins; Child; Child, Preschool; DNA-Bindin

1999