mitomycin has been researched along with Innate Inflammatory Response in 20 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rationale for combining anticancer drugs has not been applied consistently to use of intravesical agents for treatment of superficial bladder cancer, for which immunotherapeutic BCG and chemotherapeutic mitomycin seem to be a potentially effective combination." | 9.12 | Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial. ( Attisani, F; Capelli, G; De Carolis, A; Di Stasi, SM; Giannantoni, A; Giurioli, A; Stephen, RL; Storti, L; Valenti, M; Vespasiani, G; Zampa, G, 2006) |
| "We aimed to investigate the prophylactic effect simvastatin of and mitomycin C (MMC) on laryngeal and tracheal stenosis in tracheotomised rats by histopathological evaluation of laryngotracheal segment." | 7.88 | Profilactic role of simvastatin and mitomycin C in tracheal stenosis after tracheal damage: Study in rats. ( Ekinci, A; Erdoğan, AS; Kesici, H; Koc, S, 2018) |
| "Mitomycin C 40 mg in 40 ml water was administered intravesically every week for 8 consecutive weeks to 60 patients with superficial bladder cancer." | 7.67 | Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa. ( Block, NL; Brannen, G; Cummings, KB; Flanagan, M; Issell, BF; Levin, EA; Prout, GR; Soloway, MS; Summers, JL; Veenema, R, 1984) |
| "Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery." | 5.72 | Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022) |
| "The rationale for combining anticancer drugs has not been applied consistently to use of intravesical agents for treatment of superficial bladder cancer, for which immunotherapeutic BCG and chemotherapeutic mitomycin seem to be a potentially effective combination." | 5.12 | Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial. ( Attisani, F; Capelli, G; De Carolis, A; Di Stasi, SM; Giannantoni, A; Giurioli, A; Stephen, RL; Storti, L; Valenti, M; Vespasiani, G; Zampa, G, 2006) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "We aimed to investigate the prophylactic effect simvastatin of and mitomycin C (MMC) on laryngeal and tracheal stenosis in tracheotomised rats by histopathological evaluation of laryngotracheal segment." | 3.88 | Profilactic role of simvastatin and mitomycin C in tracheal stenosis after tracheal damage: Study in rats. ( Ekinci, A; Erdoğan, AS; Kesici, H; Koc, S, 2018) |
| "To study the differential effects of bacillus Calmette-Guérin (BCG) and mitomycin C (MMC) intravesical therapy on the false-positive rate of PDD of bladder cancer." | 3.76 | Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy. ( Bosch, JL; Draga, RO; Grimbergen, MC; Jonges, TN; Kok, ET; van Swol, CF, 2010) |
| "To determine the clinical significance of postoperative conjunctival inflammation noted at the third or fourth week after intraoperative application of mitomycin C and amniotic membrane transplantation for pterygium." | 3.74 | Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium. ( Casas, V; Kheirkhah, A; Raju, VK; Sheha, H; Tseng, SC, 2008) |
| "Mitomycin C 40 mg in 40 ml water was administered intravesically every week for 8 consecutive weeks to 60 patients with superficial bladder cancer." | 3.67 | Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa. ( Block, NL; Brannen, G; Cummings, KB; Flanagan, M; Issell, BF; Levin, EA; Prout, GR; Soloway, MS; Summers, JL; Veenema, R, 1984) |
| "The healing and scarring determine the percentage of patients achieving low final intraocular pressures (IOPs) that are associated with virtually no glaucoma progression." | 2.44 | Modulation of wound healing during and after glaucoma surgery. ( Brocchini, S; Dahlmann-Noor, A; Georgoulas, S; Khaw, PT, 2008) |
| "Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery." | 1.72 | Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Vinokurtseva, A | 1 |
| Armstrong, JJ | 1 |
| Liu, H | 1 |
| Hutnik, CML | 1 |
| Tambe, PK | 1 |
| Qsee, HS | 1 |
| Bharati, S | 1 |
| Ekinci, A | 1 |
| Koc, S | 1 |
| Erdoğan, AS | 1 |
| Kesici, H | 1 |
| Ali, MJ | 1 |
| Paulsen, F | 1 |
| Uyeturk, U | 1 |
| Gucuk, A | 1 |
| Firat, T | 1 |
| Kemahli, E | 1 |
| Kukner, A | 1 |
| Ozyalvacli, ME | 1 |
| da Costa Paula, C | 1 |
| Julio, G | 1 |
| Campos, P | 1 |
| Pujol, P | 1 |
| Asaad, M | 1 |
| Georgoulas, S | 1 |
| Dahlmann-Noor, A | 1 |
| Brocchini, S | 1 |
| Khaw, PT | 1 |
| Sahiner, N | 1 |
| Kravitz, DJ | 1 |
| Qadir, R | 1 |
| Blake, DA | 1 |
| Haque, S | 1 |
| John, VT | 1 |
| Margo, CE | 1 |
| Ayyala, RS | 1 |
| Draga, RO | 1 |
| Grimbergen, MC | 1 |
| Kok, ET | 1 |
| Jonges, TN | 1 |
| van Swol, CF | 1 |
| Bosch, JL | 1 |
| Sen, E | 1 |
| Balikoglu-Yilmaz, M | 1 |
| Bozdag-Pehlivan, S | 1 |
| Sungu, N | 1 |
| Aksakal, FN | 1 |
| Altinok, A | 1 |
| Tuna, T | 1 |
| Unlu, N | 1 |
| Ustun, H | 1 |
| Koklu, G | 1 |
| Öztürk, F | 1 |
| Helming, L | 1 |
| Choi, S | 1 |
| Cheong, Y | 1 |
| Shin, JH | 1 |
| Kim, KA | 1 |
| Bang, JB | 1 |
| Jin, KH | 1 |
| Park, HK | 1 |
| Di Stasi, SM | 1 |
| Giannantoni, A | 1 |
| Giurioli, A | 1 |
| Valenti, M | 1 |
| Zampa, G | 1 |
| Storti, L | 1 |
| Attisani, F | 1 |
| De Carolis, A | 1 |
| Capelli, G | 1 |
| Vespasiani, G | 1 |
| Stephen, RL | 1 |
| Kureshi, F | 1 |
| Kalaaji, AN | 1 |
| Halvorson, L | 1 |
| Pittelkow, MR | 1 |
| Davis, MD | 1 |
| Pelz, JO | 1 |
| Doerfer, J | 1 |
| Decker, M | 1 |
| Dimmler, A | 1 |
| Hohenberger, W | 1 |
| Meyer, T | 1 |
| Kheirkhah, A | 1 |
| Casas, V | 1 |
| Sheha, H | 1 |
| Raju, VK | 1 |
| Tseng, SC | 1 |
| Issell, BF | 1 |
| Prout, GR | 1 |
| Soloway, MS | 1 |
| Cummings, KB | 1 |
| Brannen, G | 1 |
| Veenema, R | 1 |
| Flanagan, M | 1 |
| Block, NL | 1 |
| Summers, JL | 1 |
| Levin, EA | 1 |
| Kasimis, BS | 1 |
| Miller, JB | 1 |
| Kaneshiro, CA | 1 |
| Forbes, KA | 1 |
| Moran, EM | 1 |
| Metter, GE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intravesical Instillation Therapy With Bacillus Calmette-Guérin (BCG) and Sequential BCG and Electromotive Mitomycin-C (EMDA-MCC) in Patients With High-risk Non-muscle-invasive Bladder Carcinoma[NCT03664869] | Phase 3 | 300 participants (Anticipated) | Interventional | 2018-10-26 | Recruiting | ||
| Intravesical Electromotive Mitomycin for High Risk Urothelial Non-muscle Invasive Bladder Cancer After Intravesical Bacillus Calmette-Guérin Failure[NCT04311580] | Phase 2 | 52 participants (Actual) | Interventional | 2000-01-01 | Completed | ||
| Sequential Bacillus Calmette-Guérin and Electromotive Mitomycin-C Versus Bacillus Calmette-Guérin Alone for High Risk Superficial Bladder Cancer: a Prospective Randomised Study[NCT01442519] | Phase 3 | 212 participants (Actual) | Interventional | 1994-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mitomycin and Innate Inflammatory Response
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Ultrastructure of the lacrimal drainage system in health and disease: A major review.
Topics: Bacteria; Biofilms; Cicatrix; Constriction, Pathologic; Dacryocystorhinostomy; Fibrinolytic Agents; | 2019 |
Modulation of wound healing during and after glaucoma surgery.
Topics: Antibiotics, Antineoplastic; Cicatrix; Dendrimers; Fibroblasts; Filtering Surgery; Glaucoma; Humans; | 2008 |
5 trials available for mitomycin and Innate Inflammatory Response
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery.
Topics: Administration, Topical; Adult; Aged; Antibiotics, Antineoplastic; Conjunctiva; Conjunctivitis; Fema | 2017 |
Effect of doxycycline on postoperative scarring after trabeculectomy in an experimental rabbit model.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blister; Cicatrix; Conjunctiva; Doxycyc | 2010 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Carc | 2006 |
Cyclophosphamide versus 5-fluorouracil, doxorubicin, and mitomycin C (FAM') in the treatment of hormone-resistant metastatic carcinoma of the prostate: a preliminary report of a randomized trial.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; | 1985 |
13 other studies available for mitomycin and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery.
Topics: Aspirin; Cell Transdifferentiation; Cells, Cultured; Chromatography, Liquid; Cicatrix; Collagen; Cyt | 2022 |
Mito-TEMPO mitigates 5-fluorouracil-induced intestinal injury via attenuating mitochondrial oxidative stress, inflammation, and apoptosis: an in vivo study.
Topics: Animals; Antioxidants; Apoptosis; Inflammation; Male; Mice; Mitochondria; Mitomycin; Oxidative Stres | 2023 |
Profilactic role of simvastatin and mitomycin C in tracheal stenosis after tracheal damage: Study in rats.
Topics: Alkylating Agents; Animals; Anticholesteremic Agents; Female; Fibrosis; Inflammation; Laryngostenosi | 2018 |
Effect of mitomycin, bevacizumab, and 5-Fluorouracil to inhibit urethral fibrosis in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Bevacizumab; Collagen; Disease | 2014 |
Creation of a drug-coated glaucoma drainage device using polymer technology: in vitro and in vivo studies.
Topics: Alkylating Agents; Animals; Conjunctiva; Cornea; Drug Delivery Systems; Fibrosis; Glaucoma Drainage | 2009 |
Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy.
Topics: Administration, Intravesical; Aminolevulinic Acid; Antibiotics, Antineoplastic; BCG Vaccine; Biopsy; | 2010 |
Inflammation: cell recruitment versus local proliferation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood; Cell Proliferation; Cisplatin; Filar | 2011 |
Short-term response of mitomycin C on the human rectus muscle following strabismus surgery: histological, ultrastructural, and biomechanical evaluation.
Topics: Histocytochemistry; Humans; Immunohistochemistry; Inflammation; Microscopy, Atomic Force; Microscopy | 2013 |
Cutaneous complications of intravesical treatments for bladder cancer: granulomatous inflammation of the penis following BCG therapy and penile gangrene following mitomycin therapy.
Topics: Administration, Intravesical; Aged; Antibiotics, Antineoplastic; BCG Vaccine; Carcinoma, Transitiona | 2006 |
Hyperthermic intraperitoneal chemoperfusion (HIPEC) decrease wound strength of colonic anastomosis in a rat model.
Topics: Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusio | 2007 |
Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium.
Topics: Adult; Aged; Aged, 80 and over; Amnion; Conjunctivitis; Female; Fibrin Tissue Adhesive; Follow-Up St | 2008 |
Mitomycin C intravesical therapy in noninvasive bladder cancer after failure on thiotepa.
Topics: Adult; Aged; Drug Evaluation; Humans; Inflammation; Middle Aged; Mitomycin; Mitomycins; Skin Disease | 1984 |