mitomycin has been researched along with Injuries, Radiation in 33 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multi-institutional phase 2 trial assessed the utility of dose-painted intensity modulated radiation therapy (DP-IMRT) in reducing grade 2+ combined acute gastrointestinal and genitourinary adverse events (AEs) of 5-fluorouracil (5FU) and mitomycin-C (MMC) chemoradiation for anal cancer by at least 15% compared with the conventional radiation/5FU/MMC arm from RTOG 9811." | 5.17 | RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. ( Esthappan, J; Goodyear, MD; Haddock, MG; Kachnic, LA; Myerson, RJ; Parikh, PJ; Rotman, M; Safran, H; Willett, CG; Willins, J; Winter, K, 2013) |
| "Radiation Therapy Oncology Group (RTOG) 92-08 began as a single arm, Phase II trial for patients with anal cancer consisting of radiation (RT) + 5-flourouracil + mitomycin-C with a mandatory 2-week break and was amended after completion to evaluate the same treatment regimen without a treatment break." | 5.13 | Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08. ( Garcia, M; John, M; Konski, A; Krieg, R; Myerson, R; Pinover, W; Willett, C, 2008) |
| "During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure." | 3.91 | Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019) |
| "Deleterious oral mucositis (OM) develops during radiotherapy (RT) or chemoradiotherapy for head-and-neck cancer (HNC) patients." | 2.77 | Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer. ( Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH, 2012) |
| "Anal squamous cell carcinoma has rarely been reported in the setting of ulcerative colitis." | 1.62 | Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols? ( Click, B; Hull, TL; Lightner, AL; McMichael, J; Regueiro, M; Steele, SR; Vaidya, P, 2021) |
| "For 70 women with anal cancer treated at our department, acute and chronic side effects and quality of life (QoL) were evaluated with questionnaires using the Common Terminology Criteria for Adverse Events (CTCAE v." | 1.51 | Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects. ( Adeberg, S; Debus, J; Haefner, MF; Herfarth, K; Koerber, SA; Krug, D; Liermann, J; Seither, B; Slynko, A; Sterzing, F, 2019) |
| " Patient acute gastrointestinal toxicity was recorded using Common Terminology Criteria of Adverse Events (CTCAE) diarrhoea grading." | 1.48 | Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes. ( Amor, H; Blakey, D; Chao, M; Guerrieri, M; Guiney, M; Ho, H; Macleod, C; Melven, L; Ng, M; Skelton, J; Subramanian, B, 2018) |
| "The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life." | 1.39 | Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013) |
| "Pterygium is a common UV-induced degeneration of the limbal conjunctiva." | 1.36 | [Pterygium. Etiology, clinical aspects and novel adjuvant therapies]. ( Cursiefen, C; Heindl, LM, 2010) |
| "Mitomycin-C application has being shown useful adjunct to surgical technique in managing nasopharyngeal stenosis for surgeons." | 1.35 | Velopharyngeal stenosis, a late complication of radiotherapy. ( Kumar, SS; Lee, SC; Singh, A; Singh, S; Tang, IP, 2009) |
| "31 patients with advanced cervical cancer qualified for the study." | 1.33 | Preliminary results of mitomycin C local application as post-treatment prevention of vaginal radiation-induced morbidity in women with cervical cancer. ( Fijuth, J; Markowska, J; Pietraszek, A; Sobotkowski, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (27.27) | 18.2507 |
| 2000's | 11 (33.33) | 29.6817 |
| 2010's | 12 (36.36) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Lightner, AL | 1 |
| Vaidya, P | 1 |
| McMichael, J | 1 |
| Click, B | 1 |
| Regueiro, M | 1 |
| Steele, SR | 1 |
| Hull, TL | 1 |
| Ng, M | 1 |
| Ho, H | 1 |
| Skelton, J | 1 |
| Guerrieri, M | 1 |
| Guiney, M | 1 |
| Chao, M | 1 |
| Blakey, D | 1 |
| Macleod, C | 1 |
| Amor, H | 1 |
| Subramanian, B | 1 |
| Melven, L | 1 |
| Koerber, SA | 1 |
| Seither, B | 1 |
| Slynko, A | 1 |
| Haefner, MF | 1 |
| Krug, D | 1 |
| Liermann, J | 1 |
| Adeberg, S | 1 |
| Herfarth, K | 1 |
| Debus, J | 1 |
| Sterzing, F | 1 |
| Giuliani, A | 1 |
| Romanzi, F | 1 |
| Di Sibio, A | 1 |
| Calvisi, G | 1 |
| Lombardi, L | 1 |
| Marchese, M | 1 |
| Di Staso, M | 1 |
| Schietroma, M | 1 |
| Carlei, F | 1 |
| Romano, L | 1 |
| Huddart, RA | 1 |
| Hall, E | 1 |
| Hussain, SA | 1 |
| Jenkins, P | 2 |
| Rawlings, C | 1 |
| Tremlett, J | 1 |
| Crundwell, M | 1 |
| Adab, FA | 1 |
| Sheehan, D | 1 |
| Syndikus, I | 1 |
| Hendron, C | 1 |
| Lewis, R | 1 |
| Waters, R | 1 |
| James, ND | 1 |
| Doyen, J | 1 |
| Benezery, K | 1 |
| Follana, P | 1 |
| Ortholan, C | 2 |
| Gérard, JP | 1 |
| Hannoun-Levi, JM | 1 |
| Gal, J | 1 |
| Francois, E | 1 |
| Call, JA | 1 |
| Prendergast, BM | 1 |
| Jensen, LG | 1 |
| Ord, CB | 1 |
| Goodman, KA | 1 |
| Jacob, R | 1 |
| Mell, LK | 1 |
| Thomas, CR | 1 |
| Jabbour, SK | 1 |
| Miller, RC | 1 |
| Troussier, I | 1 |
| Huguet, F | 1 |
| Servagi-Vernat, S | 1 |
| Benahim, C | 1 |
| Khalifa, J | 1 |
| Darmon, I | 1 |
| Krebs, L | 1 |
| Dejean, C | 1 |
| Fenoglietto, P | 1 |
| Vieillot, S | 1 |
| Bensadoun, RJ | 1 |
| Thariat, J | 1 |
| Franco, P | 1 |
| Ragona, R | 1 |
| Arcadipane, F | 1 |
| Mistrangelo, M | 1 |
| Cassoni, P | 1 |
| Rondi, N | 1 |
| Morino, M | 1 |
| Racca, P | 1 |
| Ricardi, U | 1 |
| Myerson, RJ | 2 |
| Outlaw, ED | 1 |
| Chang, A | 1 |
| Birnbaum, EH | 1 |
| Fleshman, JW | 1 |
| Grigsby, PW | 1 |
| Kodner, IJ | 1 |
| Malayapa, RS | 1 |
| Mutch, MG | 1 |
| Parikh, P | 1 |
| Picus, J | 1 |
| Tan, BR | 1 |
| Lee, SC | 1 |
| Tang, IP | 1 |
| Singh, A | 1 |
| Kumar, SS | 1 |
| Singh, S | 1 |
| Anderson, S | 1 |
| Wronski, S | 1 |
| Ashton, A | 1 |
| Heindl, LM | 1 |
| Cursiefen, C | 1 |
| Yen, SH | 1 |
| Wang, LW | 1 |
| Lin, YH | 1 |
| Jen, YM | 1 |
| Chung, YL | 1 |
| Yi, SK | 1 |
| Mak, W | 1 |
| Yang, CC | 1 |
| Liu, T | 1 |
| Cui, J | 1 |
| Chen, AM | 1 |
| Purdy, JA | 1 |
| Monjazeb, AM | 1 |
| Do, L | 1 |
| Kachnic, LA | 1 |
| Winter, K | 1 |
| Goodyear, MD | 1 |
| Willins, J | 1 |
| Esthappan, J | 1 |
| Haddock, MG | 1 |
| Rotman, M | 1 |
| Parikh, PJ | 1 |
| Safran, H | 1 |
| Willett, CG | 1 |
| John, M | 2 |
| Flam, M | 1 |
| Palma, N | 1 |
| Lorvidhaya, V | 1 |
| Chitapanarux, I | 1 |
| Sangruchi, S | 1 |
| Lertsanguansinchai, P | 1 |
| Kongthanarat, Y | 1 |
| Tangkaratt, S | 1 |
| Visetsiri, E | 1 |
| Vuong, T | 1 |
| Devic, S | 1 |
| Belliveau, P | 1 |
| Muanza, T | 1 |
| Hegyi, G | 1 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Kim, S | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Ezzat, M | 1 |
| Shouman, T | 1 |
| Zaza, K | 1 |
| Safwat, A | 1 |
| El-Khoudary, A | 1 |
| El-Senosi, M | 1 |
| Ezzat, I | 1 |
| Sobotkowski, J | 1 |
| Markowska, J | 1 |
| Fijuth, J | 1 |
| Pietraszek, A | 1 |
| Konski, A | 1 |
| Garcia, M | 1 |
| Krieg, R | 1 |
| Pinover, W | 1 |
| Myerson, R | 1 |
| Willett, C | 1 |
| Witzigmann, H | 1 |
| Sagasser, J | 1 |
| Meyer, FM | 1 |
| Witte, J | 1 |
| Fernando, IN | 1 |
| Powles, TJ | 1 |
| Ashley, S | 1 |
| Grafton, D | 1 |
| Harmer, CL | 1 |
| Ford, HT | 1 |
| Rakovitch, E | 1 |
| Fyles, AW | 1 |
| Pintilie, M | 1 |
| Leung, PM | 1 |
| Watanabe, H | 1 |
| Hirota, S | 1 |
| Soejima, T | 1 |
| Honda, K | 1 |
| Kono, K | 1 |
| Hishikawa, Y | 1 |
| Obayasi, K | 1 |
| Takada, Y | 1 |
| Smith, TJ | 1 |
| Ryan, LM | 1 |
| Douglass, HO | 1 |
| Haller, DG | 1 |
| Dayal, Y | 1 |
| Kirkwood, J | 1 |
| Tormey, DC | 1 |
| Schutt, AJ | 1 |
| Hinson, J | 1 |
| Sischy, B | 1 |
| Munker, R | 1 |
| Purmale, L | 1 |
| Aydemir, U | 1 |
| Reitmeier, M | 1 |
| Pohlmann, H | 1 |
| Schorer, H | 1 |
| Hartenstein, R | 1 |
| Mai, SK | 1 |
| Grieger, J | 1 |
| Lachmann, R | 1 |
| Bohrer, M | 1 |
| Tiefenbacher, U | 1 |
| Wenz, F | 1 |
| Sommer, K | 1 |
| Brockmann, WP | 1 |
| Wiegel, T | 1 |
| Krüll, A | 1 |
| Hübener, KH | 1 |
| Birk, S | 1 |
| Seydel, HG | 1 |
| Stablein, DM | 1 |
| Leichman, LP | 1 |
| Kinzie, JJ | 1 |
| Thomas, PR | 1 |
| Koga, K | 1 |
| Minoda, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of the Efficacy of Adjuvant Chemotherapy in Patients With Residual Lesions After Concurrent Radiochemotherapy for Locally Advanced Cervical Cancer[NCT04409860] | 120 participants (Anticipated) | Interventional | 2020-05-26 | Recruiting | |||
| A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas[NCT00685763] | 13 participants (Actual) | Interventional | 2008-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00685763)
Timeframe: 1 year following the completion of radiation therapy
| Intervention | participants (Number) |
|---|---|
| Proton Radiation and Chemotherapy | 0 |
10 trials available for mitomycin and Injuries, Radiation
| Article | Year |
|---|---|
Randomized noninferiority trial of reduced high-dose volume versus standard volume radiation therapy for muscle-invasive bladder cancer: results of the BC2001 trial (CRUK/01/004).
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemo | 2013 |
A phase II trial of induction chemotherapy followed by continuous hyperfractionated accelerated radiotherapy in locally advanced non-small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; C | 2009 |
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; E | 2012 |
RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal.
Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Analysis of Variance; Antineoplastic Combined Chemothera | 2013 |
Concurrent mitomycin C, 5-fluorouracil, and radiotherapy in the treatment of locally advanced carcinoma of the cervix: a randomized trial.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; B | 2003 |
Contribution of conformal therapy in the treatment of anal canal carcinoma with combined chemotherapy and radiotherapy: results of a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel | 2003 |
A randomized study of accelerated fractionation radiotherapy with and without mitomycin C in the treatment of locally advanced head and neck cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; C | 2005 |
Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colo | 2008 |
An acute toxicity study on the effects of synchronous chemotherapy and radiotherapy in early stage breast cancer after conservative surgery.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Comb | 1996 |
Combined chemoradiotherapy vs. radiotherapy alone for early stage squamous cell carcinoma of the esophagus: a study of the Eastern Cooperative Oncology Group.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comb | 1998 |
23 other studies available for mitomycin and Injuries, Radiation
| Article | Year |
|---|---|
Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel | 2021 |
Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes.
Topics: Abdominal Cavity; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; An | 2018 |
Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc | 2019 |
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si | 2019 |
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac | 2013 |
Intensity-modulated Radiation Therapy for Anal Cancer: Results From a Multi-Institutional Retrospective Cohort Study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape | 2016 |
[Management of locally advanced anal canal carcinoma with modulated arctherapy and concurrent chemotherapy].
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell | 2015 |
Lumbar-sacral bone marrow dose modeling for acute hematological toxicity in anal cancer patients treated with concurrent chemo-radiation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow; Chemoradio | 2016 |
Radiotherapy for epidermoid carcinoma of the anus: thirty years' experience.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols | 2009 |
Velopharyngeal stenosis, a late complication of radiotherapy.
Topics: Administration, Topical; Antibiotics, Antineoplastic; Chemotherapy, Adjuvant; Choanal Atresia; Combi | 2009 |
[Pterygium. Etiology, clinical aspects and novel adjuvant therapies].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibod | 2010 |
Development of a standardized method for contouring the lumbosacral plexus: a preliminary dosimetric analysis of this organ at risk among 15 patients treated with intensity-modulated radiotherapy for lower gastrointestinal cancers and the incidence of rad
Topics: Anatomic Landmarks; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Fluorouracil; Hu | 2012 |
Ten-year results of chemoradiation for anal cancer: focus on late morbidity.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb | 1996 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
Preliminary results of mitomycin C local application as post-treatment prevention of vaginal radiation-induced morbidity in women with cervical cancer.
Topics: Antibiotics, Antineoplastic; Brachytherapy; Female; Humans; Iridium Radioisotopes; Middle Aged; Mito | 2006 |
[Therapy of anal cancer].
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therap | 1994 |
Role of mitomycin C in the development of late bowel toxicity following chemoradiation for locally advanced carcinoma of the cervix.
Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplas | 1997 |
[Endoscopic findings of esophagitis in concurrent chemo-radiotherapy for lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell | 1998 |
Advanced head and neck cancer: long-term results of chemo-radiotherapy, complications and induction of second malignancies.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cobalt Radioisotopes; Combined Moda | 2001 |
Radiochemotherapy for anal carcinoma - effectivity and late toxicity.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc | 2002 |
[The therapeutic results and early and late toxicities of the treatment of anal canal carcinoma by radiotherapy or chemoradiotherapy].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combine | 1991 |
Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera | 1990 |
[Interstitial pneumonia developed after combination chemotherapy with (CDDP, VDS, MMC) and radiotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Mod | 1990 |