mitomycin has been researched along with Infertility in 5 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Infertility: A reduced or absent capacity to reproduce.
Excerpt | Relevance | Reference |
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" Compared with Fancc(-)(/)(-) mice lacking FANCC, a component of the FA core complex, Helq(gt/gt) mice exhibited a mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker mitomycin C." | 3.79 | Helq acts in parallel to Fancc to suppress replication-associated genome instability. ( Akre, MK; Johnson, CS; Kawabata, T; Lee, WL; Luebben, SW; O'Sullivan, MG; Shima, N, 2013) |
"Fanconi anemia (FA) is a human autosomal recessive cancer susceptibility disorder characterized by cellular sensitivity to mitomycin C and ionizing radiation." | 3.71 | Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. ( D'Andrea, AD; Hays, T; Kuang, Y; Lu, N; Montes De Oca, R; Moreau, L; Seed, B; Yang, Y, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
Authors | Studies |
---|---|
Pan, Y | 1 |
Yang, X | 1 |
Zhang, F | 1 |
Chen, S | 1 |
Zhou, Z | 1 |
Yin, H | 1 |
Ma, H | 1 |
Shang, L | 1 |
Yang, J | 1 |
Li, G | 1 |
Wang, Y | 1 |
Jin, L | 1 |
Shi, Q | 1 |
Wu, Y | 1 |
Luebben, SW | 1 |
Kawabata, T | 1 |
Akre, MK | 1 |
Lee, WL | 1 |
Johnson, CS | 1 |
O'Sullivan, MG | 1 |
Shima, N | 1 |
Bleuyard, JY | 1 |
Gallego, ME | 1 |
Savigny, F | 1 |
White, CI | 1 |
Yang, Y | 1 |
Kuang, Y | 1 |
Montes De Oca, R | 1 |
Hays, T | 1 |
Moreau, L | 1 |
Lu, N | 1 |
Seed, B | 1 |
D'Andrea, AD | 1 |
Koomen, M | 1 |
Cheng, NC | 1 |
van de Vrugt, HJ | 1 |
Godthelp, BC | 1 |
van der Valk, MA | 1 |
Oostra, AB | 1 |
Zdzienicka, MZ | 1 |
Joenje, H | 1 |
Arwert, F | 1 |
5 other studies available for mitomycin and Infertility
Article | Year |
---|---|
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
Topics: Alkylating Agents; Animals; Base Sequence; Disease Models, Animal; DNA Repair; Embryo, Mammalian; Fa | 2021 |
Helq acts in parallel to Fancc to suppress replication-associated genome instability.
Topics: Alleles; Animals; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cross-Linking Reagents; DNA He | 2013 |
Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cross-Linking Reagents; DNA Repair; DNA-Bind | 2005 |
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.
Topics: Alleles; Animals; Chromosome Breakage; Disease Models, Animal; DNA-Binding Proteins; Fanconi Anemia; | 2001 |
Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice.
Topics: Animals; DNA; DNA Damage; DNA-Binding Proteins; Drug Hypersensitivity; Fanconi Anemia; Fanconi Anemi | 2002 |