mitomycin has been researched along with Infertility in 5 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Infertility: A reduced or absent capacity to reproduce.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compared with Fancc(-)(/)(-) mice lacking FANCC, a component of the FA core complex, Helq(gt/gt) mice exhibited a mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker mitomycin C." | 3.79 | Helq acts in parallel to Fancc to suppress replication-associated genome instability. ( Akre, MK; Johnson, CS; Kawabata, T; Lee, WL; Luebben, SW; O'Sullivan, MG; Shima, N, 2013) |
| "Fanconi anemia (FA) is a human autosomal recessive cancer susceptibility disorder characterized by cellular sensitivity to mitomycin C and ionizing radiation." | 3.71 | Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. ( D'Andrea, AD; Hays, T; Kuang, Y; Lu, N; Montes De Oca, R; Moreau, L; Seed, B; Yang, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pan, Y | 1 |
| Yang, X | 1 |
| Zhang, F | 1 |
| Chen, S | 1 |
| Zhou, Z | 1 |
| Yin, H | 1 |
| Ma, H | 1 |
| Shang, L | 1 |
| Yang, J | 1 |
| Li, G | 1 |
| Wang, Y | 1 |
| Jin, L | 1 |
| Shi, Q | 1 |
| Wu, Y | 1 |
| Luebben, SW | 1 |
| Kawabata, T | 1 |
| Akre, MK | 1 |
| Lee, WL | 1 |
| Johnson, CS | 1 |
| O'Sullivan, MG | 1 |
| Shima, N | 1 |
| Bleuyard, JY | 1 |
| Gallego, ME | 1 |
| Savigny, F | 1 |
| White, CI | 1 |
| Yang, Y | 1 |
| Kuang, Y | 1 |
| Montes De Oca, R | 1 |
| Hays, T | 1 |
| Moreau, L | 1 |
| Lu, N | 1 |
| Seed, B | 1 |
| D'Andrea, AD | 1 |
| Koomen, M | 1 |
| Cheng, NC | 1 |
| van de Vrugt, HJ | 1 |
| Godthelp, BC | 1 |
| van der Valk, MA | 1 |
| Oostra, AB | 1 |
| Zdzienicka, MZ | 1 |
| Joenje, H | 1 |
| Arwert, F | 1 |
5 other studies available for mitomycin and Infertility
| Article | Year |
|---|---|
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
Topics: Alkylating Agents; Animals; Base Sequence; Disease Models, Animal; DNA Repair; Embryo, Mammalian; Fa | 2021 |
Helq acts in parallel to Fancc to suppress replication-associated genome instability.
Topics: Alleles; Animals; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cross-Linking Reagents; DNA He | 2013 |
Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cross-Linking Reagents; DNA Repair; DNA-Bind | 2005 |
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.
Topics: Alleles; Animals; Chromosome Breakage; Disease Models, Animal; DNA-Binding Proteins; Fanconi Anemia; | 2001 |
Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice.
Topics: Animals; DNA; DNA Damage; DNA-Binding Proteins; Drug Hypersensitivity; Fanconi Anemia; Fanconi Anemi | 2002 |