mitomycin has been researched along with Hypopharyngeal Cancer in 10 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study is to evaluate the efficacy of a dose-escalated, accelerated, and hyperfractionated radiotherapy schedule with a concomitant single dose of mitomycin C in the treatment of patients with advanced laryngeal or hypopharyngeal cancer." | 9.11 | Biweekly escalated, accelerated hyperfractionated radiotherapy with concomitant single-dose mitomycin C results in a high rate of local control in advanced laryngeal and hypopharyngeal cancer. ( Aaltonen, LM; Atula, T; Kajanti, M; Kouri, M; Mäkitie, A; Mäntylä, M; Saarilahti, K, 2004) |
| "The purpose of this study is to evaluate the efficacy of a dose-escalated, accelerated, and hyperfractionated radiotherapy schedule with a concomitant single dose of mitomycin C in the treatment of patients with advanced laryngeal or hypopharyngeal cancer." | 5.11 | Biweekly escalated, accelerated hyperfractionated radiotherapy with concomitant single-dose mitomycin C results in a high rate of local control in advanced laryngeal and hypopharyngeal cancer. ( Aaltonen, LM; Atula, T; Kajanti, M; Kouri, M; Mäkitie, A; Mäntylä, M; Saarilahti, K, 2004) |
| "The potential of Mitomycin C in combination with fractionated irradiation to inhibit tumour cell repopulation of a fast growing squamous cell carcinoma after fractionated radiotherapy was investigated in vivo." | 1.31 | Mitomycin C in combination with radiotherapy as a potent inhibitor of tumour cell repopulation in a human squamous cell carcinoma. ( Bamberg, M; Belka, C; Budach, W; Classen, J; Marini, P; Paulsen, F; Scheithauer, H; Welz, S, 2002) |
| "Fifty-seven patients with advanced squamous carcinoma of the larynx and hypopharynx were entered on a pilot study of initial therapy using split course radiation therapy combined with simultaneous chemotherapy using mitomycin-C and 5-fluorouracil." | 1.27 | A pilot study of mitomycin-C/5-fluorouracil infusion combined with split course radiation therapy for carcinomas of the larynx and hypopharynx. ( Beale, FA; Cummings, BJ; Elhakim, T; Harwood, AR; Keane, TJ; Payne, DG; Rawlinson, E, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hess, AK | 1 |
| Müer, A | 1 |
| Mairinger, FD | 1 |
| Weichert, W | 1 |
| Stenzinger, A | 1 |
| Hummel, M | 1 |
| Budach, V | 3 |
| Tinhofer, I | 1 |
| Patterson, JM | 1 |
| McColl, E | 1 |
| Carding, PN | 1 |
| Hildreth, AJ | 1 |
| Kelly, C | 1 |
| Wilson, JA | 1 |
| Stromberger, C | 1 |
| Poettgen, C | 1 |
| Baumann, M | 1 |
| Budach, W | 2 |
| Grabenbauer, G | 1 |
| Marnitz, S | 1 |
| Olze, H | 1 |
| Wernecke, KD | 1 |
| Ghadjar, P | 1 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Kim, S | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Saarilahti, K | 1 |
| Kajanti, M | 1 |
| Atula, T | 1 |
| Mäkitie, A | 1 |
| Aaltonen, LM | 1 |
| Kouri, M | 1 |
| Mäntylä, M | 1 |
| Thomas, C | 1 |
| Koh, WJ | 1 |
| Keane, TJ | 2 |
| Cummings, BJ | 2 |
| O'Sullivan, B | 1 |
| Payne, D | 1 |
| Rawlinson, E | 2 |
| MacKenzie, R | 1 |
| Danjoux, C | 1 |
| Hodson, I | 1 |
| Schrader, M | 1 |
| Schipper, J | 1 |
| Jahnke, K | 1 |
| Stuschke, M | 1 |
| Sack, H | 1 |
| Paulsen, F | 1 |
| Welz, S | 1 |
| Classen, J | 1 |
| Scheithauer, H | 1 |
| Marini, P | 1 |
| Belka, C | 1 |
| Bamberg, M | 1 |
| Harwood, AR | 1 |
| Beale, FA | 1 |
| Payne, DG | 1 |
| Elhakim, T | 1 |
5 trials available for mitomycin and Hypopharyngeal Cancer
5 other studies available for mitomycin and Hypopharyngeal Cancer
| Article | Year |
|---|---|
Swallowing in the first year after chemoradiotherapy for head and neck cancer: clinician- and patient-reported outcomes.
Topics: Adult; Aged; Antineoplastic Agents; Chemoradiotherapy; Cisplatin; Deglutition; Deglutition Disorders | 2014 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
Regarding Keane et al.'s randomized trial comparing radiation alone to concomitant infusional 5-flurorouracil, bolus mitomycin-C and split-course radiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Hypopharyngeal Neoplasms; Lary | 1994 |
Mitomycin C in combination with radiotherapy as a potent inhibitor of tumour cell repopulation in a human squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Combined Modality Therapy; Humans; Hypopharyngeal | 2002 |
A pilot study of mitomycin-C/5-fluorouracil infusion combined with split course radiation therapy for carcinomas of the larynx and hypopharynx.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Therapy, Combination; Female; | 1986 |