mitomycin has been researched along with Hypogonadism in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compared with Fancc(-)(/)(-) mice lacking FANCC, a component of the FA core complex, Helq(gt/gt) mice exhibited a mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker mitomycin C." | 3.79 | Helq acts in parallel to Fancc to suppress replication-associated genome instability. ( Akre, MK; Johnson, CS; Kawabata, T; Lee, WL; Luebben, SW; O'Sullivan, MG; Shima, N, 2013) |
| "The sisters also had microcephaly, and one sister was in long-term remission from leukemia, which had been diagnosed when she was 5 years old." | 1.48 | Essential Role of BRCA2 in Ovarian Development and Function. ( Ben-Moshe, A; Dreifuss, A; Gerlitz, O; Goldberg, M; Gulsuner, S; Kalifa, R; King, MC; Levy-Lahad, E; Lobel, O; Rachmiel, M; Renbaum, P; Segel, R; Shore, T; Walsh, T; Weinberg-Shukron, A; Zangen, D; Zeligson, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinberg-Shukron, A | 1 |
| Rachmiel, M | 1 |
| Renbaum, P | 1 |
| Gulsuner, S | 1 |
| Walsh, T | 1 |
| Lobel, O | 1 |
| Dreifuss, A | 1 |
| Ben-Moshe, A | 1 |
| Zeligson, S | 1 |
| Segel, R | 1 |
| Shore, T | 1 |
| Kalifa, R | 1 |
| Goldberg, M | 1 |
| King, MC | 1 |
| Gerlitz, O | 1 |
| Levy-Lahad, E | 1 |
| Zangen, D | 1 |
| Luebben, SW | 1 |
| Kawabata, T | 1 |
| Akre, MK | 1 |
| Lee, WL | 1 |
| Johnson, CS | 1 |
| O'Sullivan, MG | 1 |
| Shima, N | 1 |
2 other studies available for mitomycin and Hypogonadism
| Article | Year |
|---|---|
Essential Role of BRCA2 in Ovarian Development and Function.
Topics: Adolescent; Animals; BRCA2 Protein; Chromosome Breakage; DNA Mutational Analysis; DNA Repair; Drosop | 2018 |
Helq acts in parallel to Fancc to suppress replication-associated genome instability.
Topics: Alleles; Animals; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cross-Linking Reagents; DNA He | 2013 |