mitomycin has been researched along with Hyperplasia in 11 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "MRI showed that the scar adhesion and scar area of the MMC-PLA group were significantly reduced compared with those of the PLA, MMC, and saline groups." | 5.46 | Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs. ( Gu, Y; Liu, J; Tang, F; Wang, BB; Wu, J; Wu, T; Xie, H; Xie, N, 2017) |
| "Local delivery of mitomycin C had no favorable effect on the inhibition of intimal hyperplasia compared with control saline-treated arteries." | 3.69 | Late effects of locally delivered mitomycin C on formation of neointima and on vasomotor response to acetylcholine. ( Escaned, J; Murphy, ES; Serruys, PW; Strauss, BH; van der Giessen, WJ; van Houten, R; van Suylen, RJ; Verdouw, PD; Wilson, RA, 1994) |
| "The authors studied the effect of bladder instillation of mitomycin C (MMC), a potential carcinogen, on the duration and severity of the hyperplasia induced by transurethral fulguration." | 3.67 | Mutual neoplastic promotion by instillation of mitomycin C and cauterization on rat bladder urothelium. ( Akaza, H; Koseki, K; Niijima, T, 1986) |
| "MRI showed that the scar adhesion and scar area of the MMC-PLA group were significantly reduced compared with those of the PLA, MMC, and saline groups." | 1.46 | Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs. ( Gu, Y; Liu, J; Tang, F; Wang, BB; Wu, J; Wu, T; Xie, H; Xie, N, 2017) |
| "Although experimental induction of bladder cancer with powerful carcinogens may completely overwhelm host defenses and result in more and higher grade neoplasms, similar tumors may occur after exposure to substances not generally considered to be carcinogenic." | 1.27 | Bladder cancer induced by noncarcinogenic substances. ( Akaza, H; Murphy, WM; Soloway, MS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, BB | 1 |
| Xie, H | 1 |
| Wu, T | 1 |
| Xie, N | 1 |
| Wu, J | 1 |
| Gu, Y | 1 |
| Tang, F | 1 |
| Liu, J | 1 |
| Ma, IH | 1 |
| Hu, FR | 1 |
| Wang, IJ | 1 |
| Chen, WL | 1 |
| Hsu, YJ | 1 |
| Chu, HS | 1 |
| Yuan, CT | 1 |
| Hou, YC | 1 |
| Kim, BH | 1 |
| Kim, MK | 1 |
| Wee, WR | 1 |
| Oh, JY | 1 |
| Ohtani, M | 2 |
| Fukushima, S | 3 |
| Ito, N | 2 |
| Koiso, K | 2 |
| Niijima, T | 3 |
| Akaza, H | 2 |
| Murphy, WM | 1 |
| Soloway, MS | 1 |
| Okamura, T | 2 |
| Sakata, T | 1 |
| Strauss, BH | 1 |
| Wilson, RA | 1 |
| van Houten, R | 1 |
| van Suylen, RJ | 1 |
| Murphy, ES | 1 |
| Escaned, J | 1 |
| Verdouw, PD | 1 |
| Serruys, PW | 1 |
| van der Giessen, WJ | 1 |
| Shibata, MA | 1 |
| Hasegawa, R | 1 |
| Kurata, Y | 1 |
| Yamada, M | 1 |
| Tamano, S | 1 |
| Koseki, K | 1 |
| Maier, U | 1 |
| Holzner, JH | 1 |
1 trial available for mitomycin and Hyperplasia
| Article | Year |
|---|---|
[Significance of urothelial dysplasia in macroscopically normal mucosa in patients with bladder tumors. Results of a randomized study with and without intravesical mitomycin C in the prevention of recurrence].
Topics: Aged; Biopsy; Clinical Trials as Topic; Female; Humans; Hyperplasia; Male; Middle Aged; Mitomycin; M | 1985 |
10 other studies available for mitomycin and Hyperplasia
| Article | Year |
|---|---|
Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs.
Topics: Animals; Autophagy; Cicatrix; Collagen; Delayed-Action Preparations; Drug Delivery Systems; Dura Mat | 2017 |
Clinicopathologic correlation of ocular surface squamous neoplasia from a university hospital in North Taiwan 1994 to 2014.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Conjunctival Neopla | 2019 |
Clinical and pathological characteristics of ocular surface squamous neoplasia in an Asian population.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Asian People; Carcinoma in Situ; Carcinoma, S | 2013 |
Effects of intravesical instillation of antitumor drugs on the induction of preneoplastic bladder lesions in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Prec | 1983 |
Bladder cancer induced by noncarcinogenic substances.
Topics: Administration, Topical; Animals; Carcinoma, Papillary; Cisplatin; Female; Hyperplasia; Mitomycin; M | 1984 |
Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Drug Synergism; Female; H | 1984 |
Late effects of locally delivered mitomycin C on formation of neointima and on vasomotor response to acetylcholine.
Topics: Acetylcholine; Angioplasty, Balloon; Animals; Endothelium, Vascular; Hemodynamics; Hyperplasia; Ilia | 1994 |
Bladder epithelial hyperplasia in F344 rats after intravesical instillation of the antitumor chemotherapeutic agents Adriamycin and mitomycin C.
Topics: Administration, Intravesical; Animals; DNA; Doxorubicin; Epithelium; Female; Hyperplasia; Microscopy | 1990 |
Mutual neoplastic promotion by instillation of mitomycin C and cauterization on rat bladder urothelium.
Topics: Animals; Cautery; Cocarcinogenesis; Female; Hyperplasia; Microscopy, Electron, Scanning; Mitomycin; | 1986 |
[Effect of intrabladder instillation of various anticancer agents on carcinogenesis in rat bladder].
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubi | 1988 |