mitomycin has been researched along with Hypergonadotropic Hypogonadism in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compared with Fancc(-)(/)(-) mice lacking FANCC, a component of the FA core complex, Helq(gt/gt) mice exhibited a mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker mitomycin C." | 3.79 | Helq acts in parallel to Fancc to suppress replication-associated genome instability. ( Akre, MK; Johnson, CS; Kawabata, T; Lee, WL; Luebben, SW; O'Sullivan, MG; Shima, N, 2013) |
| "The sisters also had microcephaly, and one sister was in long-term remission from leukemia, which had been diagnosed when she was 5 years old." | 1.48 | Essential Role of BRCA2 in Ovarian Development and Function. ( Ben-Moshe, A; Dreifuss, A; Gerlitz, O; Goldberg, M; Gulsuner, S; Kalifa, R; King, MC; Levy-Lahad, E; Lobel, O; Rachmiel, M; Renbaum, P; Segel, R; Shore, T; Walsh, T; Weinberg-Shukron, A; Zangen, D; Zeligson, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinberg-Shukron, A | 1 |
| Rachmiel, M | 1 |
| Renbaum, P | 1 |
| Gulsuner, S | 1 |
| Walsh, T | 1 |
| Lobel, O | 1 |
| Dreifuss, A | 1 |
| Ben-Moshe, A | 1 |
| Zeligson, S | 1 |
| Segel, R | 1 |
| Shore, T | 1 |
| Kalifa, R | 1 |
| Goldberg, M | 1 |
| King, MC | 1 |
| Gerlitz, O | 1 |
| Levy-Lahad, E | 1 |
| Zangen, D | 1 |
| Luebben, SW | 1 |
| Kawabata, T | 1 |
| Akre, MK | 1 |
| Lee, WL | 1 |
| Johnson, CS | 1 |
| O'Sullivan, MG | 1 |
| Shima, N | 1 |
2 other studies available for mitomycin and Hypergonadotropic Hypogonadism
| Article | Year |
|---|---|
Essential Role of BRCA2 in Ovarian Development and Function.
Topics: Adolescent; Animals; BRCA2 Protein; Chromosome Breakage; DNA Mutational Analysis; DNA Repair; Drosop | 2018 |
Helq acts in parallel to Fancc to suppress replication-associated genome instability.
Topics: Alleles; Animals; Cells, Cultured; Chromosomal Proteins, Non-Histone; Cross-Linking Reagents; DNA He | 2013 |