mitomycin has been researched along with Hormone-Dependent Neoplasms in 7 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the past 20 years, 3,500 prostate cancer patients have been recruited in 16 phase III trials in untreated and advanced disease and in seven phase II trials in hormone-refractory, metastatic disease." | 2.69 | European Organization for Research and Treatment of Cancer (EORTC) prostate cancer trials, 1976-1996. ( Denis, L, 1998) |
| " Interim analysis did not demonstrate a favorable effect of the combination with this chemotherapeutic agent compared to orchidectomy alone (P = ." | 2.68 | Interim results on a randomized trial of mitomycin C in combination with orchidectomy for newly diagnosed metastatic prostate cancer. ( Baert, L; Billiet, I; Casselman, J; Derluyn, J; Paridaens, R; Popelier, G; Van Poppel, H; Vandenbroucke, F; Vanuytsel, L, 1995) |
| "positive cases in gastric cancer (4/40)." | 2.65 | [Sex hormone dependency and endocrine therapy in diffuse carcinoma of the stomach]. ( Kitaoka, H, 1983) |
| "Patients with early breast cancer (T1/T2) had a complete clinical resolution in 41% (16/39) of cases after MMM and in 20% (7/35) of cases following endocrine therapy compared with 14% (2/14) advanced tumours (T3/T4) following MMM and (0/12) following endocrine therapy." | 1.29 | Assesssment of the effect of pretreatment with neoadjuvant therapy on primary breast cancer. ( Coombes, RC; Corbishley, C; Ford, HT; Gazet, JC; Griffin, M; Lowndes, S; Makinde, V; Quilliam, J; Sutcliffe, R, 1996) |
| "Three human breast carcinoma xenografts, MCF-7, R-27 and T-61 serially transplanted into nude mice were treated with mitomycin C (MMC) alone, KM2210 (estra-1, 3, 5(10)-triene-3, 17 beta-diol, 3 benzoate 17-[4-(4-bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate) alone and KM2210 followed by MMC." | 1.28 | [Enhancement of antitumor activity of mitomycin C against human breast carcinoma xenografts by pretreatment with KM 2210]. ( Arisawa, Y; Fujita, S; Inoue, S; Ishibiki, K; Josui, K; Kubota, T; Kuzuoka, M; Oka, S; Suto, A; Yamamoto, T, 1990) |
| "Four human breast carcinoma strains serially transplanted into nude mice were used for the experimental chemotherapy and combination chemoendocrine therapy." | 1.27 | [Experimental chemo- and chemoendocrine therapy of human breast carcinomas serially transplanted into nude mice]. ( Koh, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kitaoka, H | 2 |
| Vandenbroucke, F | 1 |
| Van Poppel, H | 1 |
| Derluyn, J | 1 |
| Popelier, G | 1 |
| Casselman, J | 1 |
| Billiet, I | 1 |
| Vanuytsel, L | 1 |
| Paridaens, R | 1 |
| Baert, L | 1 |
| Gazet, JC | 1 |
| Coombes, RC | 1 |
| Ford, HT | 1 |
| Griffin, M | 1 |
| Corbishley, C | 1 |
| Makinde, V | 1 |
| Lowndes, S | 1 |
| Quilliam, J | 1 |
| Sutcliffe, R | 1 |
| Denis, L | 1 |
| Yamamoto, T | 1 |
| Kubota, T | 1 |
| Oka, S | 1 |
| Josui, K | 1 |
| Fujita, S | 1 |
| Arisawa, Y | 1 |
| Suto, A | 1 |
| Inoue, S | 1 |
| Kuzuoka, M | 1 |
| Ishibiki, K | 1 |
| Koh, J | 1 |
3 trials available for mitomycin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
[Sex hormone dependency and endocrine therapy in diffuse carcinoma of the stomach].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Mice; | 1983 |
Interim results on a randomized trial of mitomycin C in combination with orchidectomy for newly diagnosed metastatic prostate cancer.
Topics: Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Humans; Male; Middle Aged; Mitomycin; Neoplasm Meta | 1995 |
European Organization for Research and Treatment of Cancer (EORTC) prostate cancer trials, 1976-1996.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 1998 |
4 other studies available for mitomycin and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
[Sex hormone dependency in diffuse carcinoma of the stomach and results of chemo-endocrine therapy].
Topics: Adenocarcinoma, Scirrhous; Aged; Animals; Female; Gonadal Steroid Hormones; Humans; Male; Mice; Mice | 1984 |
Assesssment of the effect of pretreatment with neoadjuvant therapy on primary breast cancer.
Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic | 1996 |
[Enhancement of antitumor activity of mitomycin C against human breast carcinoma xenografts by pretreatment with KM 2210].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Estradiol; | 1990 |
[Experimental chemo- and chemoendocrine therapy of human breast carcinomas serially transplanted into nude mice].
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cyclophosphamide; Doxorubicin; Female; | 1988 |