Page last updated: 2024-11-06

mitomycin and Hepatitis B, Chronic

mitomycin has been researched along with Hepatitis B, Chronic in 3 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Hepatitis B, Chronic: INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.

Research Excerpts

ExcerptRelevanceReference
" Because previous studies showed that long-term telbivudine treatment improved renal function in chronic hepatitis B virus (HBV) infected patients, we conducted a case-control study to evaluate the clinical outcome of telbivudine preemptive therapy in HBV-related advanced HCC patients treated by combination chemotherapy comprising 5-fluorouracil, mitoxantrone and cisplatin (FMP)."5.19Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study. ( Chang, ML; Chen, YC; Chien, RN; Hsu, CW; Lin, CL; Yeh, C; Yeh, CT, 2014)
"A total of 29 patients (n=13 for chronic hepatitis Band n=16 for chronic hepatitis C) showed significant changes of the viral loads after TACE."2.76Potential risk factors for the reactivation of the replication of hepatitis B and C viruses after transcatheter arterial chemoembolization of hepatocellular carcinoma. ( Chen, SH; Chuang, WL; Hsieh, MY; Huang, CF; Lin, CI; Lin, ZY, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, CL1
Chien, RN1
Yeh, C1
Hsu, CW1
Chang, ML1
Chen, YC1
Yeh, CT1
Lin, CI1
Lin, ZY1
Hsieh, MY1
Huang, CF1
Chen, SH1
Chuang, WL1
Wu, XY1
Qian, JJ1
Lin, Y1
Zheng, MH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Observational, Single-center Post-marketing Surveillance Study of Telbivudine in Chronic Hepatitis B Adults With HBeAg Positive/Negative.[NCT00970216]160 participants (Actual)Observational2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

HBV-DNA < 300 Copies/mL in 48 Weeks

(NCT00970216)
Timeframe: 48 weeks

Interventionparticipants (Number)
Chronic Hepatitis B79

Trials

2 trials available for mitomycin and Hepatitis B, Chronic

ArticleYear
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
    Scandinavian journal of gastroenterology, 2014, Volume: 49, Issue:12

    Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2014
Potential risk factors for the reactivation of the replication of hepatitis B and C viruses after transcatheter arterial chemoembolization of hepatocellular carcinoma.
    The Kaohsiung journal of medical sciences, 2011, Volume: 27, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocel

2011

Other Studies

1 other study available for mitomycin and Hepatitis B, Chronic

ArticleYear
Hepatitis B virus X protein disrupts DNA interstrand crosslinking agent mitomycin C induced ATR dependent intra-S-phase checkpoint.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:11

    Topics: Carcinoma, Hepatocellular; Checkpoint Kinase 1; DNA Damage; Hepatitis B, Chronic; Humans; Liver Neop

2008