mitomycin has been researched along with Hemolysis in 8 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with refractory solid tumors (n = 51) were treated with a 48-h continuous intravenous infusion of menadione followed by a bolus intravenous dose of mitomycin C at the completion of the menadione infusion." | 2.68 | Phase I study of mitomycin C and menadione in advanced solid tumors. ( Ahn, C; Akman, SA; Doroshow, JH; Leong, LA; Margolin, KA; Morgan, RJ; Raschko, JW; Somlo, G, 1995) |
| "Mitomycin C (MMC) is a water-soluble anticancer drug extensively used in first-line chemotherapy but is limited by its poor aqueous stability in vitro, rapid elimination from the body, and lack of target specificity." | 1.40 | Mitomycin C-soybean phosphatidylcholine complex-loaded self-assembled PEG-lipid-PLA hybrid nanoparticles for targeted drug delivery and dual-controlled drug release. ( Hou, Z; Huang, Y; Jia, M; Li, Y; Lin, J; Wu, H; Wu, S; Yang, X, 2014) |
| "Mitomycin C (MMC) has been known to be nephrotoxic since 1971." | 1.27 | Mitomycin C-induced renal toxicity, a dose-dependent side effect? ( de Vries, J; Pinedo, HM; Verwey, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 2 |
| Wu, H | 1 |
| Yang, X | 1 |
| Jia, M | 1 |
| Huang, Y | 1 |
| Lin, J | 1 |
| Wu, S | 1 |
| Hou, Z | 1 |
| Papo, N | 1 |
| Shai, Y | 1 |
| SOKAWA, Y | 1 |
| EGAMI, F | 1 |
| Shen, AY | 1 |
| Tsai, JH | 1 |
| Teng, HC | 1 |
| Huang, MH | 1 |
| Wu, SN | 1 |
| Margolin, KA | 1 |
| Akman, SA | 1 |
| Leong, LA | 1 |
| Morgan, RJ | 1 |
| Somlo, G | 1 |
| Raschko, JW | 1 |
| Ahn, C | 1 |
| Doroshow, JH | 1 |
| Sugiyama, K | 1 |
| Inoue, K | 1 |
| Sakazaki, R | 1 |
| Oscarsson, J | 1 |
| Westermark, M | 1 |
| Beutin, L | 1 |
| Uhlin, BE | 1 |
| Verwey, J | 1 |
| de Vries, J | 1 |
| Pinedo, HM | 1 |
1 trial available for mitomycin and Hemolysis
| Article | Year |
|---|---|
Phase I study of mitomycin C and menadione in advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Erythrocytes; Female; Glucosephosphate | 1995 |
7 other studies available for mitomycin and Hemolysis
| Article | Year |
|---|---|
Mitomycin C-soybean phosphatidylcholine complex-loaded self-assembled PEG-lipid-PLA hybrid nanoparticles for targeted drug delivery and dual-controlled drug release.
Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Glycine max; HeLa Cells; Hemolysis; | 2014 |
New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Cell Death; Cell Membrane; Fluoresceins; Hem | 2003 |
RELEASE OF THE HEMOLYTIC COMPONENT OF STREPTOLYSIN S BY ATP AND MAGNESIUM ION FROM A PROTOPLAST MEMBRANE FRACTION OF STREPTOCOCCI.
Topics: Adenosine Triphosphate; Bacterial Proteins; Biochemical Phenomena; Biochemistry; Chloramphenicol; Ch | 1965 |
Inhibition of intermediate-conductance Ca2+-activated K+ channel and cytoprotective properties of 4-piperidinomethyl-2-isopropyl-5-methylphenol.
Topics: Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysi | 2007 |
Mitomycin-supplemented washed blood agar for the isolation of Shiga toxin-producing Escherichia coli other than O157:H7.
Topics: Blood; Culture Media; Escherichia coli; Escherichia coli Proteins; Feces; Hemolysin Proteins; Hemoly | 2001 |
The bacteriophage-associated ehly1 and ehly2 determinants from Escherichia coli O26:H- strains do not encode enterohemolysins per se but cause release of the ClyA cytolysin.
Topics: Bacterial Toxins; Bacteriophage P1; Blotting, Western; Erythrocytes; Escherichia coli; Escherichia c | 2002 |
Mitomycin C-induced renal toxicity, a dose-dependent side effect?
Topics: Adult; Aged; Dose-Response Relationship, Drug; Female; Hemolysis; Hemolytic-Uremic Syndrome; Humans; | 1987 |