mitomycin has been researched along with Hemoglobinuria, Paroxysmal in 2 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Hemoglobinuria, Paroxysmal: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The diagnostic feature of FA is increased chromosomal breakage in blood lymphocytes cultured with diepoxybutane or mitomycin C." | 3.80 | Comparison of chromosome breakage in non-mosaic and mosaic patients with Fanconi anemia, relatives, and patients with other inherited bone marrow failure syndromes. ( Alter, BP; Fargo, JH; Giri, N; Olson, SB; Rochowski, A; Savage, SA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tummala, H | 1 |
| Kirwan, M | 1 |
| Walne, AJ | 1 |
| Hossain, U | 1 |
| Jackson, N | 1 |
| Pondarre, C | 1 |
| Plagnol, V | 1 |
| Vulliamy, T | 1 |
| Dokal, I | 1 |
| Fargo, JH | 1 |
| Rochowski, A | 1 |
| Giri, N | 1 |
| Savage, SA | 1 |
| Olson, SB | 1 |
| Alter, BP | 1 |
2 other studies available for mitomycin and Hemoglobinuria, Paroxysmal
| Article | Year |
|---|---|
ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function.
Topics: Acetylcysteine; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cell Line, Tu | 2014 |
Comparison of chromosome breakage in non-mosaic and mosaic patients with Fanconi anemia, relatives, and patients with other inherited bone marrow failure syndromes.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Failure Disorders; Chil | 2014 |