mitomycin has been researched along with Heart Failure in 7 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-six patients with recurrent metastatic breast cancer were treated with a combination chemotherapy including doxorubicin and mitomycin C." | 3.67 | Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C. ( Brambilla, MC; Comazzi, R; Genitoni, V; Guindani, A; Lacaita, G; Villani, F; Volonterio, A, 1985) |
| "A 23-year-old male patient with plasma cell leukemia showed characteristic clinical features: accelerating heart failure and consciousness disturbance accompanied with an increase of plasma cells in peripheral blood." | 1.29 | [Primary plasma cell leukemia complicated with high-output cardiac failure and hyperammonemia]. ( Hata, H; Kawaguchi, T; Kuribayashi, N; Matsuzaki, H; Nakahashi, E; Shimizu, K; Takatsuki, K; Tsuji, N, 1994) |
| "Two percent had congestive heart failure associated with doxorubicin." | 1.27 | Early and delayed clinical cardiotoxicity of doxorubicin. ( Blumenschein, GR; Buzdar, AU; Marcus, C; Smith, TL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rjiba-Touati, K | 1 |
| Ayed-Boussema, I | 1 |
| Belarbia, A | 1 |
| Mokni, M | 1 |
| Achour, A | 1 |
| Bacha, H | 1 |
| Abid, S | 1 |
| Nakahashi, E | 1 |
| Kuribayashi, N | 1 |
| Tsuji, N | 1 |
| Kawaguchi, T | 1 |
| Hata, H | 1 |
| Matsuzaki, H | 1 |
| Shimizu, K | 1 |
| Takatsuki, K | 1 |
| Mackintosh, J | 1 |
| Sivanesaratnam, V | 1 |
| Verweij, J | 1 |
| Stoter, G | 1 |
| Buzdar, AU | 1 |
| Marcus, C | 1 |
| Smith, TL | 1 |
| Blumenschein, GR | 1 |
| Villani, F | 1 |
| Comazzi, R | 1 |
| Lacaita, G | 1 |
| Guindani, A | 1 |
| Genitoni, V | 1 |
| Volonterio, A | 1 |
| Brambilla, MC | 1 |
1 review available for mitomycin and Heart Failure
| Article | Year |
|---|---|
Severe side effects of the cytotoxic drug mitomycin-C.
Topics: Animals; Heart Failure; Hepatic Veno-Occlusive Disease; Humans; Kidney Diseases; Mitomycin; Mitomyci | 1987 |
6 other studies available for mitomycin and Heart Failure
| Article | Year |
|---|---|
Role of recombinant human erythropoietin against mitomycin C-induced cardiac, hepatic and renal dysfunction in Wistar rats.
Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Chemical and Drug Induced Liver Injury; Drug A | 2015 |
[Primary plasma cell leukemia complicated with high-output cardiac failure and hyperammonemia].
Topics: Adult; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Cardiac Output; Dexamethasone; Doxor | 1994 |
Cardiopulmonary complications of mitomycin-C.
Topics: Anemia, Hemolytic; Female; Heart Failure; Humans; Hypertension, Pulmonary; Middle Aged; Mitomycin; M | 1990 |
Mitomycin-C cardiotoxicity.
Topics: Carcinoma, Squamous Cell; Female; Heart Failure; Humans; Middle Aged; Mitomycin; Mitomycins; Uterine | 1989 |
Early and delayed clinical cardiotoxicity of doxorubicin.
Topics: Adult; Aged; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cyclo | 1985 |
Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 1985 |