Page last updated: 2024-11-06

mitomycin and HIV Coinfection

mitomycin has been researched along with HIV Coinfection in 24 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"However, anal cancers are rare in patients with HIV in Japan."1.43[Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV]. ( Ishida, H; Mita, E; Mori, K; Nakazuru, S; Nishio, K; Sakakibara, Y; Sugimoto, A; Uehira, T; Yajima, K; Yamada, T, 2016)
"Anal cancer is uncommon."1.42Review of anal cancer patients at the Ottawa hospital. ( Abunassar, M; Asmis, T; Jonker, DJ; Reinders, J, 2015)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."1.39Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"Sixty patients with anal cancer were identified."1.38Chemoradiotherapy for anal cancer in HIV patients causes prolonged CD4 cell count suppression. ( Alfa-Wali, M; Allen-Mersh, T; Antoniou, A; Bower, M; Gazzard, B; Nelson, M; Newsom-Davis, T; Tait, D, 2012)
"HIV-positive patients with squamous cell carcinoma of the canal treated at Continuum Cancer Centers-affiliated hospitals were identified from tumor registries."1.36Efficacy and toxicity of chemoradiation in the treatment of HIV-associated anal cancer. ( Ennis, RD; Evans, A; Grossbard, M; Hauerstock, D, 2010)
"The median CD4 count at diagnosis of anal cancer was 209 cells/microl (range: 29-380 cells/microl), 5 had prior AIDS defining diagnoses."1.31Treatment of HIV-associated invasive anal cancer with combined chemoradiation. ( Bower, M; Cleator, S; Fife, K; Gazzard, B; Nelson, M; Phillips, R, 2000)
"Retrospective review of 50 MO anal cancer patients treated from 1984-1994."1.30Time-dose considerations in the treatment of anal cancer. ( Constantinou, EC; Daly, W; DeLaney, TF; Fung, CY; Kaufman, DS; Willett, CG, 1997)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (20.83)18.2507
2000's5 (20.83)29.6817
2010's12 (50.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Martin, D1
Schreckenbach, T1
Ziegler, P1
Filmann, N1
Kalinauskaite, G1
Tinhofer, I1
Budach, V1
Gani, C1
Zips, D1
Schimek-Jasch, T1
Schäfer, H1
Grosu, AL1
Thomas, E1
Krause, M1
Dapper, H1
Combs, S1
Hoffmann, C1
Stuschke, M1
Walter, F1
Belka, C1
Kurth, I1
Hadiwikarta, WW1
Baumann, M1
Rödel, C2
Fokas, E1
Leiker, AJ1
Wang, CJ1
Sanford, NN1
Aguilera, TA1
Karri, S1
Beg, MS1
Kazmi, SA1
Olson, C1
Matthews, JA1
Abdelnaby, A1
Meyer, JJ1
Folkert, MR1
Glynne-Jones, R1
Sclafani, F1
Rao, S1
Doyen, J1
Benezery, K1
Follana, P1
Ortholan, C1
Gérard, JP1
Hannoun-Levi, JM1
Gal, J1
Francois, E1
Fraunholz, IB1
Haberl, A2
Klauke, S1
Gute, P1
Rödel, CM1
Abunassar, M1
Reinders, J1
Jonker, DJ1
Asmis, T1
Sugimoto, A1
Nakazuru, S1
Sakakibara, Y1
Nishio, K1
Yamada, T1
Ishida, H1
Yajima, K1
Uehira, T1
Mori, K1
Mita, E1
Hogg, ME1
Popowich, DA1
Wang, EC1
Kiel, KD1
Stryker, SJ1
Halverson, AL1
Fraunholz, I1
Weiss, C1
Eberlein, K1
Abbas, A1
Yang, G1
Fakih, M1
Hammad, N1
Heilbrun, LK1
Gupta, S1
Tageja, N1
Philip, PA1
Shields, AF1
Smith, D1
El-Rayes, BF1
Hauerstock, D1
Ennis, RD1
Grossbard, M1
Evans, A1
Alfa-Wali, M1
Allen-Mersh, T1
Antoniou, A1
Tait, D1
Newsom-Davis, T1
Gazzard, B2
Nelson, M2
Bower, M2
Shields, CL1
Ramasubramanian, A1
Mellen, PL1
Shields, JA1
Edelman, S1
Johnstone, PA1
Oehler-Jänne, C1
Seifert, B1
Lütolf, UM1
Ciernik, IF1
Konstantinopoulos, PA1
Schlecht, HP1
Bryan, B1
Pantanowitz, L1
Dezube, BJ1
Phillips, DM1
Tan, X1
Pearce-Pratt, R1
Zacharopoulos, VR1
Bottomley, DM1
Aqel, N1
Selvaratnam, G1
Phillips, RH1
Peddada, AV1
Smith, DE1
Rao, AR1
Frost, DB1
Kagan, AR1
Constantinou, EC1
Daly, W1
Fung, CY1
Willett, CG1
Kaufman, DS1
DeLaney, TF1
Höcht, S1
Wiegel, T1
Kroesen, AJ1
Berdel, WE1
Runkel, N1
Hinkelbein, W1
Cleator, S1
Fife, K1
Phillips, R1

Reviews

2 reviews available for mitomycin and HIV Coinfection

ArticleYear
Systemic Therapies for Advanced Squamous Cell Anal Cancer.
    Current oncology reports, 2018, 05-04, Volume: 20, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Biomarkers, Tumor; Carcinoma, Squamo

2018
Management of anal cancer in 2010. Part 2: current treatment standards and future directions.
    Oncology (Williston Park, N.Y.), 2010, Apr-30, Volume: 24, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin;

2010

Trials

1 trial available for mitomycin and HIV Coinfection

ArticleYear
Local tumor control and toxicity in HIV-associated anal carcinoma treated with radiotherapy in the era of antiretroviral therapy.
    Radiation oncology (London, England), 2006, Aug-18, Volume: 1

    Topics: Adult; Aged; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Anus Neoplasms; Combined

2006

Other Studies

21 other studies available for mitomycin and HIV Coinfection

ArticleYear
Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: A multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2022, Volume: 167

    Topics: Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradiotherapy; HIV Infections; Humans; Mitomycin; Prog

2022
Feasibility and Outcome of Routine Use of Concurrent Chemoradiation in HIV-positive Patients With Squamous Cell Anal Cancer.
    American journal of clinical oncology, 2020, Volume: 43, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chemoradio

2020
Chemotherapy, "Lighting the Fire" or "Releasing the Brakes" in Metastatic Anal Cancer.
    Diseases of the colon and rectum, 2017, Volume: 60, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Catheter A

2017
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2013
Long-term effects of chemoradiotherapy for anal cancer in patients with HIV infection: oncological outcomes, immunological status, and the clinical course of the HIV disease.
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms;

2014
Review of anal cancer patients at the Ottawa hospital.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neo

2015
[Squamous cell carcinoma of the anal canal treated with chemoradiotherapy in a patient with HIV].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2016, Volume: 113, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Che

2016
HIV and anal cancer outcomes: a single institution's experience.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:5

    Topics: Antineoplastic Agents; Anus Neoplasms; Capecitabine; Carcinoma, Squamous Cell; Chemotherapy, Adjuvan

2009
Concurrent chemoradiotherapy with 5-fluorouracil and mitomycin C for invasive anal carcinoma in human immunodeficiency virus-positive patients receiving highly active antiretroviral therapy.
    International journal of radiation oncology, biology, physics, 2010, Volume: 76, Issue:5

    Topics: Adult; Aged; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy

2010
Squamous cell cancer of the anal canal in HIV-infected patients receiving highly active antiretroviral therapy: a single institution experience.
    American journal of clinical oncology, 2011, Volume: 34, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral T

2011
Efficacy and toxicity of chemoradiation in the treatment of HIV-associated anal cancer.
    Clinical colorectal cancer, 2010, Volume: 9, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2010
Chemoradiotherapy for anal cancer in HIV patients causes prolonged CD4 cell count suppression.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Capecitabine; CD4 Lymph

2012
Conjunctival squamous cell carcinoma arising in immunosuppressed patients (organ transplant, human immunodeficiency virus infection).
    Ophthalmology, 2011, Volume: 118, Issue:11

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Conjunctival Neoplasms; Female; Graft Rejection; HIV Infectio

2011
Combined modality therapy for HIV-infected patients with squamous cell carcinoma of the anus: outcomes and toxicities.
    International journal of radiation oncology, biology, physics, 2006, Sep-01, Volume: 66, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cis

2006
HIV-associated anal squamous cell cancer: an otherwise preventable disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Anus Neoplasm

2006
An assay for HIV infection of cultured human cervix-derived cells.
    Journal of virological methods, 1995, Volume: 52, Issue:1-2

    Topics: Cell Line; Cell Survival; Cells, Cultured; Cervix Uteri; Epithelium; Female; HIV; HIV Infections; Hu

1995
Epidermoid anal cancer in HIV infected patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Combined M

1996
Chemotherapy and low-dose radiotherapy in the treatment of HIV-infected patients with carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 1997, Mar-15, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

1997
Time-dose considerations in the treatment of anal cancer.
    International journal of radiation oncology, biology, physics, 1997, Oct-01, Volume: 39, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Anus Neoplasms; Combine

1997
Low acute toxicity of radiotherapy and radiochemotherapy in patients with cancer of the anal canal and HIV-infection.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Dr

1997
Treatment of HIV-associated invasive anal cancer with combined chemoradiation.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therapy; Fl

2000