mitomycin has been researched along with Granulocytic Leukemia, Chronic in 3 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "FANCD2-Ub was upregulated in CD34+ chronic myeloid leukemia (CML) cells and in BCR-ABL1 kinase-positive cell lines in response to elevated levels of reactive oxygen species (ROS) and DNA cross-linking agent mitomycin C." | 1.37 | Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis. ( Blasiak, J; Glodkowska-Mrowka, E; Hoser, G; Klejman, A; Koptyra, M; Seferynska, I; Skorski, T; Stoklosa, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koptyra, M | 1 |
| Stoklosa, T | 1 |
| Hoser, G | 1 |
| Glodkowska-Mrowka, E | 1 |
| Seferynska, I | 1 |
| Klejman, A | 1 |
| Blasiak, J | 1 |
| Skorski, T | 2 |
| Falinski, R | 1 |
| Nieborowska-Skorska, M | 1 |
| Konstantinov, SM | 1 |
| Topashka-Ancheva, M | 1 |
| Benner, A | 1 |
| Berger, MR | 1 |
3 other studies available for mitomycin and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis.
Topics: Animals; Cell Line; DNA Breaks, Double-Stranded; Fanconi Anemia Complementation Group D2 Protein; Fu | 2011 |
BCR-ABL1 kinase facilitates localization of acetylated histones 3 and 4 on DNA double-strand breaks.
Topics: Acetylation; Animals; Cells, Cultured; Chromatin Assembly and Disassembly; DNA Breaks, Double-Strand | 2012 |
Alkylphosphocholines: Effects on human leukemic cell lines and normal bone marrow cells.
Topics: Alkylation; Animals; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cell Cycle; Cell Division; | 1998 |