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mitomycin and Glioma

mitomycin has been researched along with Glioma in 14 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"The effect of chemotherapy drug Mitomycin C (MMC) in combination with recombinant adeno-associated virus II (rAAV2) in cancer therapy was investigated, and the mechanism of MMC affecting rAAV2's bioactivity was also studied."5.39Effect and mechanism of Mitomycin C combined with recombinant adeno-associated virus type II against glioma. ( Deng, Y; Han, C; Lei, R; Ma, H; Qing, H; Rao, L; Wang, H; Xiang, J; Yang, Z; Zhang, L; Zhang, Y, 2013)
"Cytotoxic T lymphocytes (CTL) against autologous malignant brain tumor were generated in peripheral blood lymphoid cells (PBL) prepared from a patient with a malignant brain tumor by stimulation of the cultured PBL for 7 days with attenuated crossreactive malignant melanoma (MM2) cells pretreated with mitomycin C."3.69Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation. ( Fujimoto, S; Kurisaka, M; Maeda, N; Mori, K; Saitoh, S, 1997)
"The effect of chemotherapy drug Mitomycin C (MMC) in combination with recombinant adeno-associated virus II (rAAV2) in cancer therapy was investigated, and the mechanism of MMC affecting rAAV2's bioactivity was also studied."1.39Effect and mechanism of Mitomycin C combined with recombinant adeno-associated virus type II against glioma. ( Deng, Y; Han, C; Lei, R; Ma, H; Qing, H; Rao, L; Wang, H; Xiang, J; Yang, Z; Zhang, L; Zhang, Y, 2013)
"Metronidazole, 1."1.27Feasibility study of combining metronidazole with chemotherapy. ( Bélanger, R; Crook, AF; Heringer, R; Hopkins, HS; Hugenholtz, H; Maroun, JA; Richard, MT; Stewart, DJ; Yan, RC; Young, V, 1983)
" Both dosage and releasing time can be adjusted."1.27[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites]. ( Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M, 1986)
"In those with metastatic brain tumors, the median survival time was 280 days, 1-year survival rate 43."1.27[Clinical application of a sustained release anticancer pellet]. ( Aoyama, I; Handa, H; Hashi, K; Kamijyo, Y; Mori, K; Oda, Y; Okumura, T; Tokuriki, Y; Yamashita, J, 1985)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's5 (35.71)18.2507
2000's2 (14.29)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kokoshka, JM1
Ireland, CM1
Barrows, LR1
Ma, H1
Zhang, Y1
Wang, H1
Han, C1
Lei, R1
Zhang, L1
Yang, Z1
Rao, L1
Qing, H1
Xiang, J1
Deng, Y1
Li, H1
Liu, T1
Chen, X2
Xie, L1
Chen, Y1
Douglass, T1
Jeffes, EW1
Xu, Q1
Williams, CC1
Arpajirakul, N1
Delgado, C1
Kleinman, M1
Sanchez, R1
Dan, Q1
Kim, RC1
Wepsic, HT1
Jadus, MR1
Yuan, S1
Wang, Y1
Jiang, S1
Yang, Y1
Song, Y1
Tu, C1
Stewart, DJ1
Maroun, JA1
Young, V1
Crook, AF1
Hopkins, HS1
Yan, RC1
Richard, MT1
Hugenholtz, H1
Bélanger, R1
Heringer, R1
Saitoh, S1
Kurisaka, M1
Mori, K2
Maeda, N1
Fujimoto, S1
Nitta, T1
Nikkhah, G1
Tonn, JC1
Hoffmann, O1
Kraemer, HP1
Darling, JL1
Schachenmayr, W1
Schönmayr, R1
Nakamura, O1
Matsutani, M1
Nomura, K1
Takakura, K1
Kawakami, K1
Kawamoto, K1
Oka, N1
Kawamura, Y1
Matsumura, H1
Ito, T1
Ohyama, A1
Kubo, O1
Himuro, H1
Inoue, N1
Tajika, Y1
Tajika, T1
Tohyama, T1
Sakairi, M1
Yoshida, M1
Kaetsu, I1
Kitamura, K1
Ito, H1
Hasegawa, T1
Shoin, K1
Hwang, WZ1
Hayashi, M1
Yamamoto, S1
Miyazaki, I1
Oda, Y1
Kamijyo, Y1
Okumura, T1
Tokuriki, Y1
Yamashita, J1
Handa, H1
Aoyama, I1
Hashi, K1

Reviews

1 review available for mitomycin and Glioma

ArticleYear
[A history and prospect of adoptive immunotherapy against malignant glioma--past, now and future].
    No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:7

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy, Adoptive; Immunotoxins; Interleukin-2; Killer Cells,

1992

Other Studies

13 other studies available for mitomycin and Glioma

ArticleYear
Cell-based screen for identification of inhibitors of tubulin polymerization.
    Journal of natural products, 1996, Volume: 59, Issue:12

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Forma

1996
Effect and mechanism of Mitomycin C combined with recombinant adeno-associated virus type II against glioma.
    International journal of molecular sciences, 2013, Dec-19, Volume: 15, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Dependovirus; Genetic Therapy

2013
A rare case of primary congenital glaucoma in combination with neurofibromatosis 1: a case report.
    BMC ophthalmology, 2015, Oct-29, Volume: 15

    Topics: Alkylating Agents; Brain Neoplasms; Combined Modality Therapy; Glioma; Humans; Hydrophthalmos; Infan

2015
Living T9 glioma cells expressing membrane macrophage colony-stimulating factor produce immediate tumor destruction by polymorphonuclear leukocytes and macrophages via a "paraptosis"-induced pathway that promotes systemic immunity against intracranial T9
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Animals; Antibodies; Brain Neoplasms; Cell Death; Chemokines, CXC; Chemotactic Factors; Female; Free

2002
[Study on chemosensitivity assay in vitro in the peripheral blood lymphocyte and the tumor cells].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2000, Volume: 31, Issue:3

    Topics: Antineoplastic Agents; Brain Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Human

2000
Feasibility study of combining metronidazole with chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carcinoma, Sq

1983
Induction of specific cytotoxic T lymphocytes against autologous brain tumor by crossreactive allo-tumor cell stimulation.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:3

    Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Autoant

1997
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Color

1992
[Drug sensitivity test against malignant gliomas].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:6

    Topics: Animals; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Screening Assays, Antitumor; Glioma; Hu

1990
[Flow cytometric studies of brain tumors--5: New sensitivity test of antineoplastic agents for brain tumors and its clinical application].
    No shinkei geka. Neurological surgery, 1986, Volume: 14, Issue:5

    Topics: Animals; Antineoplastic Agents; Bleomycin; Brain Neoplasms; Cell Cycle; Cell Survival; Colony-Formin

1986
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
    No shinkei geka. Neurological surgery, 1986, Volume: 14, Issue:10

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysge

1986
[Necrotomy of brain stem glioma and local administration of anticancer agents].
    No shinkei geka. Neurological surgery, 1985, Volume: 13, Issue:10

    Topics: Administration, Topical; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain; B

1985
[Clinical application of a sustained release anticancer pellet].
    No shinkei geka. Neurological surgery, 1985, Volume: 13, Issue:12

    Topics: Antineoplastic Agents; Brain Neoplasms; Delayed-Action Preparations; Drug Administration Schedule; F

1985