mitomycin and Genetic Non-Disjunction studies

mitomycin and Genetic Non-Disjunction

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

Excerpt	Relevance	Reference
"The influence of sampling time on the frequencies of micronuclei, centromere-positive micronuclei and chromosome nondisjunction was investigated in binucleated lymphocytes following treatment with a known clastogen (mitomycin C) or an aneuploidy-inducing agent (vincristine sulfate)."	3.69	Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment. ( Antoccia, A; Degrassi, F; Marcos, R; Ramirez, MJ; Sgura, A; Tanzarella, C, 1997)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

2 (100.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Russo, A	1
Priante, G	1
Tommasi, AM	1
Sgura, A	1
Antoccia, A	1
Ramirez, MJ	1
Marcos, R	1
Tanzarella, C	1
Degrassi, F	1

Studies

Russo, A

Priante, G

Tommasi, AM

Sgura, A

Antoccia, A

Ramirez, MJ

Marcos, R

Tanzarella, C

Degrassi, F

Other Studies

2 other studies available for mitomycin and Genetic Non-Disjunction

Article	Year
PRINS localization of centromeres and telomeres in micronuclei indicates that in mouse splenocytes chromatid non-disjunction is a major mechanism of aneuploidy. Mutation research, 1996, Volume: 372, Issue:2 Topics: Aneuploidy; Animals; Centromere; Demecolcine; DNA; DNA, Satellite; In Situ Hybridization; Male; Mice	1996
Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment. Mutation research, 1997, Aug-01, Volume: 392, Issue:1-2 Topics: Aneuploidy; Cell Division; Centromere; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cyto	1997

Article

Year

PRINS localization of centromeres and telomeres in micronuclei indicates that in mouse splenocytes chromatid non-disjunction is a major mechanism of aneuploidy.

Mutation research, 1996, Volume: 372, Issue:2

Topics: Aneuploidy; Animals; Centromere; Demecolcine; DNA; DNA, Satellite; In Situ Hybridization; Male; Mice

1996

Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment.

Mutation research, 1997, Aug-01, Volume: 392, Issue:1-2

Topics: Aneuploidy; Cell Division; Centromere; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cyto

1997