mitomycin has been researched along with Fibrosarcoma in 26 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Concanavalin A (ConA)-bound-tumor cell vaccine of methylchoranthrene-induced fibrosarcoma (Meth 1) induced tumor-specific immunoprophylactic and immunotherapeutic response against an inoculum of live Meth 1 cells in histocompatible animals." | 7.66 | Chemo-immunotherapy of methylchoranthrene-induced fibrosarcoma by concanavalin A-bound tumor vaccine, levamisole and mitomycin C. ( Marumo, H; Morimoto, M; Okabe, M, 1982) |
| "We investigated the effects of a combination treatment involving a pulsing magnetic field (PMF) and an antitumor drug, mitomycin C (MMC), on two experimental tumors (fibrosarcoma KMT-17 and hepatocellular carcinoma KDH-8) in WKA rats, paying attention to possible potentiation of the therapeutic effect of the antitumor drug." | 3.68 | Treatment of experimental tumors with a combination of a pulsing magnetic field and an antitumor drug. ( Hosokawa, M; Kobayashi, H; Komatsumoto, M; Kubo, Y; Nakajima, S; Namieno, T; Omote, Y, 1990) |
| "Concanavalin A (ConA)-bound-tumor cell vaccine of methylchoranthrene-induced fibrosarcoma (Meth 1) induced tumor-specific immunoprophylactic and immunotherapeutic response against an inoculum of live Meth 1 cells in histocompatible animals." | 3.66 | Chemo-immunotherapy of methylchoranthrene-induced fibrosarcoma by concanavalin A-bound tumor vaccine, levamisole and mitomycin C. ( Marumo, H; Morimoto, M; Okabe, M, 1982) |
| " By considering these pharmacokinetic behaviors, a suitable method of administration should be established." | 1.27 | [Chemical modification of anticancer agents from viewpoints of their pharmacokinetics]. ( Fujita, H, 1984) |
| " These findings suggested that dicoumarol might enhance the toxicity of MC to the hypoxic cells of solid tumors, without increasing the toxic side effects of the antibiotic to the host." | 1.27 | Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro. ( Keyes, SR; Rockwell, S; Sartorelli, AC, 1985) |
| "The growth of Meth A (MA) tumors was suppressed in tumor-antigen-specific manner in BALB/c mice immunized with mitomycin C-treated MA (MMC-MA) cells in saline or in Freund's complete adjuvant (FCA)." | 1.27 | Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells. ( Himeno, K; Matsumoto, T; Miake, S; Mitani, M; Mori, K; Nomoto, K, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, B | 1 |
| Ahmed, B | 1 |
| Landuyt, W | 1 |
| Ni, Y | 1 |
| Gaspar, R | 1 |
| Roskams, T | 1 |
| de Witte, PA | 1 |
| Kong, ZL | 1 |
| Jin, YZ | 1 |
| Shimizu, M | 1 |
| Nakamura, M | 1 |
| Kataoka, T | 1 |
| Iwaguchi, T | 1 |
| Fujita, H | 1 |
| Yasunaga, T | 1 |
| Ohgaki, K | 1 |
| Inamoto, T | 1 |
| Kan, N | 1 |
| Hikasa, Y | 1 |
| Ogura, T | 4 |
| Shindo, H | 3 |
| Namba, M | 3 |
| Yamamura, Y | 3 |
| Imai, R | 1 |
| Morimoto, M | 2 |
| Marumo, H | 2 |
| Kobayashi, T | 1 |
| Tsuruo, T | 1 |
| Inaba, M | 1 |
| Tsukagoshi, S | 1 |
| Sakurai, Y | 1 |
| Okabe, M | 1 |
| Shinzato, O | 2 |
| Masuno, T | 1 |
| Inoue, T | 1 |
| Kishimoto, S | 2 |
| Sakatani, M | 1 |
| Li, T | 1 |
| Harada, M | 1 |
| Tamada, K | 1 |
| Abe, K | 1 |
| Ito, O | 1 |
| Takenoyama, M | 1 |
| Nomoto, K | 3 |
| Mantovani, F | 1 |
| Banks, L | 1 |
| Tokunaga, Y | 1 |
| Kojima, T | 1 |
| Naruse, T | 1 |
| Dorie, MJ | 1 |
| Kallman, RF | 1 |
| Soejima, Y | 1 |
| Shen, WM | 1 |
| Minato, K | 1 |
| Nishio, K | 1 |
| Sugimoto, Y | 1 |
| Fujiwara, Y | 1 |
| Tamura, T | 1 |
| Hara, K | 1 |
| Saijo, N | 1 |
| Omote, Y | 1 |
| Hosokawa, M | 1 |
| Komatsumoto, M | 1 |
| Namieno, T | 1 |
| Nakajima, S | 1 |
| Kubo, Y | 1 |
| Kobayashi, H | 1 |
| Tsujino, M | 1 |
| Mitani, M | 2 |
| Mori, K | 2 |
| Himeno, K | 2 |
| Kohya, H | 1 |
| Ebina, T | 1 |
| Yamaguchi, T | 1 |
| Ishida, N | 1 |
| Keyes, SR | 1 |
| Rockwell, S | 1 |
| Sartorelli, AC | 1 |
| Wing, MG | 1 |
| Rogers, K | 1 |
| Jacob, G | 1 |
| Rees, RC | 1 |
| Teicher, BA | 1 |
| Crawford, JM | 1 |
| Holden, SA | 1 |
| Lin, Y | 1 |
| Cathcart, KN | 1 |
| Luchette, CA | 1 |
| Flatow, J | 1 |
| Matsumoto, T | 1 |
| Miake, S | 1 |
| Ishizeki, S | 1 |
| Ohtsuka, M | 1 |
| Irinoda, K | 1 |
| Kukita, K | 1 |
| Nagaoka, K | 1 |
| Nakashima, T | 1 |
| Komiyama, K | 1 |
| Hirokawa, Y | 1 |
| Zhibo, Y | 1 |
| Umezawa, I | 1 |
| Hata, T | 1 |
26 other studies available for mitomycin and Fibrosarcoma
| Article | Year |
|---|---|
Potentiation of photodynamic therapy with hypericin by mitomycin C in the radiation-induced fibrosarcoma-1 mouse tumor model.
Topics: Animals; Anthracenes; Disease Models, Animal; Drug Synergism; Female; Fibrosarcoma; Mice; Mitomycin; | 2003 |
[Effect of inducible nitric oxide synthase on tumour cells sensitivity to mitomycin C analogue 629 in vitro].
Topics: Antibiotics, Antineoplastic; Aziridines; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Damage; Fi | 2006 |
Mechanism of the antitumor activity of 5,5'-bis(2'-tetrahydropyranyl) secalonic acid D against Meth-A.
Topics: Animals; Antineoplastic Agents; Cell Division; Female; Fibrosarcoma; In Vitro Techniques; Killer Cel | 1983 |
[Chemical modification of anticancer agents from viewpoints of their pharmacokinetics].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Doxorubicin; Fibrosarcoma; | 1984 |
Protective effect of vitamin E against immunosuppression induced by adriamycin, mitomycin C and 5-fluorouracil in mice.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Fibrosarcoma; Fluorouracil; Immunity, Cellular; I | 1983 |
Tumoricidal activity of peritoneal exudate cells from rats treated with mitomycin C.
Topics: Animals; Ascitic Fluid; Cells, Cultured; Fibrosarcoma; Macrophages; Male; Mitomycin; Mitomycins; Rat | 1980 |
Antitumor activity of 7-n-(p-hydroxyphenyl)-mitomycin C in experimental tumor systems.
Topics: Animals; Carcinoma; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibrosarcoma; Le | 1981 |
Chemo-immunotherapy of methylchoranthrene-induced fibrosarcoma by concanavalin A-bound tumor vaccine, levamisole and mitomycin C.
Topics: Animals; Concanavalin A; Drug Therapy, Combination; Fibrosarcoma; Immunotherapy; Levamisole; Male; M | 1982 |
In vitro tumor cell killing by peritoneal macrophages from mitomycin C-treated rats.
Topics: Animals; Antibiotics, Antineoplastic; Cell Adhesion; Cytotoxicity, Immunologic; Deoxyglucose; Fibros | 1982 |
Analysis of therapeutic effect in experimental chemoimmunotherapy for rat ascites tumor.
Topics: Adjuvants, Immunologic; Animals; Ascites; Cell Line; Fibrosarcoma; Male; Mitomycin; Mitomycins; Noca | 1982 |
The antitumor effect induced by local injections with interleukin-2 is diminished by combing with a local injection with mitomycin C.
Topics: Animals; Drug Administration Routes; Drug Therapy, Combination; Female; Fibrosarcoma; Interleukin-2; | 1996 |
Inhibition of E6 induced degradation of p53 is not sufficient for stabilization of p53 protein in cervical tumour derived cell lines.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma; C | 1999 |
Antitumor effect of oxycellulose as a hemostatic during operation.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Erythrocytes; Etopo | 1998 |
Reoxygenation in the RIF-1 tumor after chemotherapy.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Hypoxia; Cell Survival; Cisplatin; Cyclophosphamide; | 1992 |
The development of a treatment model for lymph node metastasis in nude mice transplanted with rat fibrosarcoma clone A.
Topics: Amputation, Surgical; Animals; Combined Modality Therapy; Fibrosarcoma; Lymphatic Metastasis; Mice; | 1991 |
Treatment of experimental tumors with a combination of a pulsing magnetic field and an antitumor drug.
Topics: Animals; Antineoplastic Agents; Cell Division; Combined Modality Therapy; Fibrosarcoma; Hot Temperat | 1990 |
[Activation and regulation of macrophages induced by inoculation of cryodestroyed tumor cells].
Topics: Animals; Antigens, Neoplasm; Cryosurgery; Fibrosarcoma; Interferon-alpha; Killer Cells, Natural; Mac | 1990 |
Anti-tumor cytostatic mechanism and delayed-type hypersensitivity against a syngeneic murine tumor. Comparison between neonatally thymectomized mice and congenitally athymic nude mice.
Topics: Animals; Animals, Newborn; Cell Division; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic | 1989 |
The "double grafted tumor system", proposed to find effector cells in the analyses of antitumor effect of BRMs.
Topics: Animals; Antibodies; Antineoplastic Agents; Cells, Cultured; Complement System Proteins; Fibrosarcom | 1989 |
Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro.
Topics: Anaerobiosis; Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Combined Modality Ther | 1985 |
Characterisation of suppressor cells generated following cryosurgery of an HSV-2-induced fibrosarcoma.
Topics: Animals; Antigen-Presenting Cells; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell T | 1988 |
Glutathione monoethyl ester can selectively protect liver from high dose BCNU or cyclophosphamide.
Topics: Amifostine; Animals; Carmustine; Cell Line; Cyclophosphamide; Drug Interactions; Fibrosarcoma; Gluta | 1988 |
Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cells, Cultured; Cytotoxicity, Immunologic; Fib | 1986 |
[Induction of activated macrophages by intraperitoneal injection of mitomycin C in mice and rats].
Topics: Animals; Concanavalin A; Dose-Response Relationship, Drug; Fibrosarcoma; Injections; Lymphokines; Ma | 1986 |
Azinomycins A and B, new antitumor antibiotics. III. Antitumor activity.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Azabicyclo Compounds; Carcinoma, Ehrlic | 1987 |
[Potentiation of chemotherapeutic activity by a Chinese herb medicine juzen-taiho-toh].
Topics: Animals; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Synergism; Drugs, Chinese Herbal; Female; Fi | 1988 |