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mitomycin and Failed Back Surgery Syndrome

mitomycin has been researched along with Failed Back Surgery Syndrome in 1 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Failed Back Surgery Syndrome: A condition of persistent pain and discomfort in the BACK and the LEG following lumbar surgery, often seen in patients enrolled in pain centers.

Research Excerpts

ExcerptRelevanceReference
"Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated."7.81Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE. ( Cai, J; Cao, X; Fu, Y; Ge, Y; Lu, C; Shi, K; Sun, Y; Yan, L, 2015)
"Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated."3.81Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE. ( Cai, J; Cao, X; Fu, Y; Ge, Y; Lu, C; Shi, K; Sun, Y; Yan, L, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, Y1
Ge, Y1
Fu, Y1
Yan, L1
Cai, J1
Shi, K1
Cao, X1
Lu, C1

Other Studies

1 other study available for mitomycin and Failed Back Surgery Syndrome

ArticleYear
Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE.
    European journal of pharmacology, 2015, Oct-15, Volume: 765

    Topics: Animals; Apoptosis; Cells, Cultured; Cicatrix; Down-Regulation; Epidural Space; Failed Back Surgery

2015