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mitomycin and Eye Disorders

mitomycin has been researched along with Eye Disorders in 18 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"To investigate the potential of colchicine to improve bleb function after trabeculectomy."7.91The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019)
"To evaluate the long-term results and complications after bare sclera pterygium excision with local application of mitomycin C and consecutive smoothing of the wound area with an excimer laser (PTK)."7.73Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C. ( Daniel, J; Mennel, S; Meyer, CH; Rodrigues, EB; Walkow, T, 2005)
"The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing."7.68Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992)
"To investigate the potential of colchicine to improve bleb function after trabeculectomy."3.91The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019)
"Retinal hemorrhages secondary to decompression retinopathy occurred following combined trabeculotomy-trabeculectomy with mitomycine-C (MMC) in one eye of a case of congenital glaucoma and pars plana vitrectomy-lensectomy in a case of vitreous condensation secondary to pars planitis."3.75Decompression retinopathy and possible risk factors. ( Guven, D; Hasiripi, H; Kalayci, D; Karakurt, A; Saricaoglu, MS, 2009)
"To evaluate the long-term results and complications after bare sclera pterygium excision with local application of mitomycin C and consecutive smoothing of the wound area with an excimer laser (PTK)."3.73Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C. ( Daniel, J; Mennel, S; Meyer, CH; Rodrigues, EB; Walkow, T, 2005)
"The use of topical mitomycin (mitomycin-C) as a medical adjunct to pterygium and glaucoma surgery is increasing."3.68Serious complications of topical mitomycin-C after pterygium surgery. ( Foster, CS; Martin, NF; Pfister, RR; Rubinfeld, RS; Speaker, MG; Stein, RM; Stoleru, S; Talley, AR, 1992)
"Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis."2.44Uses and complications of mitomycin C in ophthalmology. ( Aslanides, IM; Mearza, AA, 2007)
" These specific ocular side effects are described, caution being taken to precise the strength of the association between each side effect and the related drug by using the classification of World Health Organisation (WHO) (certain, probable, possible or unlikely)."2.44[Ocular side effects of glaucoma treatment agents]. ( Bremer, F; Ehongo, A, 2007)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (44.44)18.2507
2000's8 (44.44)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kokubun, T1
Yamamoto, K1
Sato, K1
Akaishi, T1
Shimazaki, A1
Nakamura, M1
Shiga, Y1
Tsuda, S1
Omodaka, K1
Nakazawa, T1
Saricaoglu, MS1
Kalayci, D1
Guven, D1
Karakurt, A1
Hasiripi, H1
Lee, E1
Doyle, E1
Jenkins, C1
Mevcha, A1
Calleary, J1
Gillatt, DA1
Airoldi, G1
Guidarelli, A1
Cantoni, O1
Panzeri, C1
Vantaggiato, C1
Bonato, S1
Grazia D'Angelo, M1
Falcone, S1
De Palma, C1
Tonelli, A1
Crimella, C1
Bondioni, S1
Bresolin, N1
Clementi, E1
Bassi, MT1
Rivas Jara, L1
Celis Sánchez, J1
Walkow, T1
Daniel, J1
Meyer, CH1
Rodrigues, EB1
Mennel, S1
Mearza, AA1
Aslanides, IM1
Labbé, A1
Khammari, C1
Baudouin, C1
Ehongo, A1
Bremer, F1
Singh, G1
Penna, EP1
Kloess, PM1
Yee, RW1
Hopp, LM1
MacInnis, BJ1
Hardten, DR1
Samuelson, TW1
Gupta, S1
Basti, S1
Sugar, A1
Rubinfeld, RS1
Pfister, RR1
Stein, RM1
Foster, CS1
Martin, NF1
Stoleru, S1
Talley, AR1
Speaker, MG1

Reviews

4 reviews available for mitomycin and Eye Disorders

ArticleYear
Uses and complications of mitomycin C in ophthalmology.
    Expert opinion on drug safety, 2007, Volume: 6, Issue:1

    Topics: Eye Diseases; Humans; Mitomycin; Ophthalmology

2007
[Wound healing modulation in glaucoma surgery].
    Journal francais d'ophtalmologie, 2007, Volume: 30, Issue:6

    Topics: Adult; Animals; Cataract Extraction; Child; Cicatrix; Eye Diseases; Filtering Surgery; Fluorouracil;

2007
[Ocular side effects of glaucoma treatment agents].
    Bulletin de la Societe belge d'ophtalmologie, 2007, Issue:304

    Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Eye Diseases; Ginkg

2007
Ocular toxicity of mitomycin-C.
    International ophthalmology clinics, 1999,Spring, Volume: 39, Issue:2

    Topics: Antibiotics, Antineoplastic; Conjunctival Neoplasms; Eye; Eye Diseases; Filtering Surgery; Glaucoma;

1999

Trials

1 trial available for mitomycin and Eye Disorders

ArticleYear
Mitomycin C after pterygium excision.
    Ophthalmology, 1993, Volume: 100, Issue:3

    Topics: Administration, Topical; Eye Diseases; Humans; Intraoperative Care; Mitomycin; Ophthalmic Solutions;

1993

Other Studies

13 other studies available for mitomycin and Eye Disorders

ArticleYear
The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Alkylating Agents; Animals; Blister; Colchicine; Drug Therapy, Combination; Eye Diseases; Male; Mito

2019
Decompression retinopathy and possible risk factors.
    Acta ophthalmologica, 2009, Volume: 87, Issue:1

    Topics: Child; Decompression, Surgical; Eye Diseases; Glaucoma; Humans; Intraocular Pressure; Male; Mitomyci

2009
Trabeculectomy surgery augmented with intra-Tenon injection of mitomycin C.
    Acta ophthalmologica, 2008, Volume: 86, Issue:8

    Topics: Aged; Blister; Choroid Diseases; Cysts; Eye Diseases; Glaucoma; Humans; Hyphema; Injections; Intraoc

2008
Re: Ocular side-effects of urological pharmacy.
    BJU international, 2009, Volume: 103, Issue:2

    Topics: Antineoplastic Agents; BCG Vaccine; Dimethyl Sulfoxide; Eye Diseases; Humans; Mitomycin; Urinary Bla

2009
Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin.
    Neurogenetics, 2010, Volume: 11, Issue:1

    Topics: Adult; Apoptosis; Apraxia, Ideomotor; Ataxia; Camptothecin; DNA Damage; DNA Helicases; Eye Diseases;

2010
[Mitomycin C treatment for ocular cicatricial pemphigoid].
    Archivos de la Sociedad Espanola de Oftalmologia, 2003, Volume: 78, Issue:2

    Topics: Cicatrix; Eye Diseases; Humans; Mitomycin; Pemphigoid, Bullous

2003
Long-term results after bare sclera pterygium resection with excimer smoothing and local application of mitomycin C.
    Cornea, 2005, Volume: 24, Issue:4

    Topics: Corneal Diseases; Eye Diseases; Follow-Up Studies; Granuloma; Humans; Laser Therapy; Lasers, Excimer

2005
Mitomycin-C after pterygium excision.
    Ophthalmology, 1993, Volume: 100, Issue:7

    Topics: Eye Diseases; Humans; Mitomycin; Ophthalmic Solutions; Postoperative Care; Pterygium; Recurrence

1993
Mitomycin-C after pterygium excision.
    Ophthalmology, 1993, Volume: 100, Issue:7

    Topics: Eye Diseases; Humans; Intraoperative Care; Mitomycin; Ophthalmic Solutions; Postoperative Care; Pter

1993
Mightomycin.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1997, Volume: 32, Issue:6

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Cell Division; Eye Diseases; Fibroblasts; Huma

1997
Corneoscleral, ciliary body, and vitreoretinal toxicity after excessive instillation of mitomycin C.
    American journal of ophthalmology, 1992, Oct-15, Volume: 114, Issue:4

    Topics: Adult; Ciliary Body; Corneal Diseases; Eye Diseases; Female; Humans; Mitomycin; Pterygium; Retinal D

1992
Who should receive mitomycin-C after pterygium surgery?
    Ophthalmology, 1992, Volume: 99, Issue:11

    Topics: Eye Diseases; Humans; Mitomycin; Postoperative Complications; Pterygium; Recurrence

1992
Serious complications of topical mitomycin-C after pterygium surgery.
    Ophthalmology, 1992, Volume: 99, Issue:11

    Topics: Adult; Aged; Calcinosis; Cataract; Contraindications; Corneal Diseases; Eye Diseases; Female; Humans

1992