Page last updated: 2024-11-06

mitomycin and Esophageal Stricture

mitomycin has been researched along with Esophageal Stricture in 42 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Mitomycin C application significantly reduced the number of dilatation sessions needed to alleviate dysphagia in patients with caustic esophageal strictures."9.17Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial. ( Abdelkader, HM; El-Asmar, KM; Hamza, AF; Hassan, MA, 2013)
"This prospective study aimed to evaluate the feasibility and safety of locoregional mitomycin C (MMC) injection to treat refractory esophageal strictures after endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma."9.16Locoregional mitomycin C injection for esophageal stricture after endoscopic submucosal dissection. ( Arakawa, T; Fujiwara, Y; Machida, H; Minamino, H; Okazaki, H; Sugimori, S; Tanigawa, T; Tominaga, K; Watanabe, K; Watanabe, T; Yamagami, H, 2012)
" The question addressed was 'Can mitomycin facilitate endoscopic dilatation treatment of benign esophageal stricture (mainly including caustic and anastomotic esophageal stricture)?' Altogether, 115 papers were found using the reported search, of which 6 represented the best evidence to answer the clinical question, which included 1 randomized controlled trial, 1 systematic review and 4 cohort studies."8.95Can mitomycin facilitate endoscopic dilatation treatment of benign oesophageal stricture? ( Chen, LQ; Deng, HY; Lin, YD; Wang, WP, 2017)
"To determine the efficacy of topical Mitomycin C application for recurrent benign esophageal strictures."8.93Topical Mitomycin C application in the treatment of refractory benign esophageal strictures in adults and comprehensive literature review. ( Bartel, MJ; Clayton, D; Jeffers, K; Raimondo, M; Seeger, K; Wallace, MB; Woodward, TA, 2016)
"The short-term results of topical Mitomycin C application for refractory esophageal stricture reported in the literature are very encouraging."8.88Mitomycin C in the therapy of recurrent esophageal strictures: hype or hope? ( Berger, M; Lacher, M; Ure, B, 2012)
"The aim of this study was to investigate the efficacy and safety of endoscopic local infiltration of mitomycin C (MMC) after oesophageal dilation for children suffering from refractory postcorrosive oesophageal stricture (OS)."7.91Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children. ( Abdullateef, KS; Arafa, A; Elkadi, R; Mansour, O; Mohamed, W; Qinawy, M; Raslan, H; Seleim, H; Wishahy, AMK; Yassin, T, 2019)
"There was a highly significant difference in the improvement of dysphagia grade at the end of follow up in the mitomycin C group (p=0."7.81A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children. ( Ezzat, WF; Fawaz, SA; Sabri, SM; Sweed, AS, 2015)
"Intramuscular injection of mitomycin C or dexamethasone may prolong the dysphagia-free period and decrease the frequency of repeat dilations compared with conventional endoscopic dilations in patients with benign esophageal strictures."7.81Intramuscular injection of mitomycin C combined with endoscopic dilation for benign esophageal strictures. ( Chen, JP; Fan, ZN; Liu, L; Wang, X; Zhang, Y, 2015)
" In 12 patients of caustic induced esophageal stricture, who failed to respond despite rigorous dilatation regimen for more than one year, a trial of topical mitomycin-C application to improve dilatation results was undertaken, considering the recently reported efficacy and safety of this agent."7.80Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures. ( Katiyar, P; Nagaich, N; Nijhawan, S; Rathore, M; Sharma, R, 2014)
"The aim of the present study was to evaluate the efficacy and short-term safety of topical mitomycin-C, an antifibrotic agent, in preventing the recurrence of anastomotic strictures after surgical repair of esophageal atresia (EA)."7.80Topical mitomycin-C application in recurrent esophageal strictures after surgical repair of esophageal atresia. ( Chapuy, L; Faure, C; Pomerleau, M, 2014)
" We report the successful use of mitomycin C in a young boy in whom we could achieve ongoing relief of dysphagia after the unsuccessful long-term use of frequent endoscopic dilatations."7.74[Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy]. ( Fröhlich, T; Greess, H; Köhler, H, 2007)
"We describe a novel technique of endoluminal delivery and focused application of mitomycin-C to an esophageal stricture that avoids inadvertent topical application to adjacent mucosa."7.74Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery. ( Baird, R; Blair, GK; Heran, MK; Skarsgard, ED, 2008)
"Mitomycin C is an antiproliferative agent that has been used successfully as an adjunct treatment in ophthalmological procedures, in the management of laryngeal and tracheal stenosis, and more recently to prevent the recurrence of caustic esophageal strictures in children."7.73Mitomycin C: an alternative conservative treatment for refractory esophageal stricture in children? ( Fayoux, P; Gottrand, F; Guimber, D; Michaud, L; Turck, D; Uhlen, S; Vachin, F, 2006)
"To assess the role of mitomycin C (MMC) in the management of pharyngoesophageal stricture after total laryngopharyngectomy and free flap reconstruction."7.72Mitomycin C for the treatment of pharyngoesophageal stricture after total laryngopharyngectomy and microvascular free tissue reconstruction. ( Annino, DJ; Goguen, LA, 2003)
"Research on long-term use of mitomycin C (MC) for recurrent esophageal stenoses is limited."5.51Efficacy and Safety of the Local Application of Mitomycin C to Recurrent Esophageal Strictures in Children. ( Bridenne, M; Fayoux, P; Gottrand, F; Hauser, B; Lachaux, A; Lemale, J; Ley, D; Michaud, L; Rebouissoux, L; Viala, J, 2019)
"The median dysphagia score decreased from 2 (1 to 3) to 0 (0 to 2) after application (P<0."5.46Topical Mitomycin C Application Is Effective Even in Esophageal Strictures Resistant to Dilatation Therapy in Children. ( Divarci, E; Dokumcu, Z; Erdener, A; Kilic, O; Ozcan, C, 2017)
"Mitomycin-C 0."5.34Topical application of mitomycin-C in oesophageal strictures. ( Afzal, N; Cameron, D; Ibarguen-Secchia, E; Köhler, H; Lewindon, P; Lindley, KJ; Mahler, T; Rosseneu, S; Schwagten, K; Thomson, M; Yerushalmi, B, 2007)
"Mitomycin C application significantly reduced the number of dilatation sessions needed to alleviate dysphagia in patients with caustic esophageal strictures."5.17Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial. ( Abdelkader, HM; El-Asmar, KM; Hamza, AF; Hassan, MA, 2013)
"This prospective study aimed to evaluate the feasibility and safety of locoregional mitomycin C (MMC) injection to treat refractory esophageal strictures after endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma."5.16Locoregional mitomycin C injection for esophageal stricture after endoscopic submucosal dissection. ( Arakawa, T; Fujiwara, Y; Machida, H; Minamino, H; Okazaki, H; Sugimori, S; Tanigawa, T; Tominaga, K; Watanabe, K; Watanabe, T; Yamagami, H, 2012)
" The question addressed was 'Can mitomycin facilitate endoscopic dilatation treatment of benign esophageal stricture (mainly including caustic and anastomotic esophageal stricture)?' Altogether, 115 papers were found using the reported search, of which 6 represented the best evidence to answer the clinical question, which included 1 randomized controlled trial, 1 systematic review and 4 cohort studies."4.95Can mitomycin facilitate endoscopic dilatation treatment of benign oesophageal stricture? ( Chen, LQ; Deng, HY; Lin, YD; Wang, WP, 2017)
"To determine the efficacy of topical Mitomycin C application for recurrent benign esophageal strictures."4.93Topical Mitomycin C application in the treatment of refractory benign esophageal strictures in adults and comprehensive literature review. ( Bartel, MJ; Clayton, D; Jeffers, K; Raimondo, M; Seeger, K; Wallace, MB; Woodward, TA, 2016)
"The short-term results of topical Mitomycin C application for refractory esophageal stricture reported in the literature are very encouraging."4.88Mitomycin C in the therapy of recurrent esophageal strictures: hype or hope? ( Berger, M; Lacher, M; Ure, B, 2012)
"The aim of this study was to investigate the efficacy and safety of endoscopic local infiltration of mitomycin C (MMC) after oesophageal dilation for children suffering from refractory postcorrosive oesophageal stricture (OS)."3.91Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children. ( Abdullateef, KS; Arafa, A; Elkadi, R; Mansour, O; Mohamed, W; Qinawy, M; Raslan, H; Seleim, H; Wishahy, AMK; Yassin, T, 2019)
"There was a highly significant difference in the improvement of dysphagia grade at the end of follow up in the mitomycin C group (p=0."3.81A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children. ( Ezzat, WF; Fawaz, SA; Sabri, SM; Sweed, AS, 2015)
"Intramuscular injection of mitomycin C or dexamethasone may prolong the dysphagia-free period and decrease the frequency of repeat dilations compared with conventional endoscopic dilations in patients with benign esophageal strictures."3.81Intramuscular injection of mitomycin C combined with endoscopic dilation for benign esophageal strictures. ( Chen, JP; Fan, ZN; Liu, L; Wang, X; Zhang, Y, 2015)
"The aim of the present study was to evaluate the efficacy and short-term safety of topical mitomycin-C, an antifibrotic agent, in preventing the recurrence of anastomotic strictures after surgical repair of esophageal atresia (EA)."3.80Topical mitomycin-C application in recurrent esophageal strictures after surgical repair of esophageal atresia. ( Chapuy, L; Faure, C; Pomerleau, M, 2014)
" In 12 patients of caustic induced esophageal stricture, who failed to respond despite rigorous dilatation regimen for more than one year, a trial of topical mitomycin-C application to improve dilatation results was undertaken, considering the recently reported efficacy and safety of this agent."3.80Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures. ( Katiyar, P; Nagaich, N; Nijhawan, S; Rathore, M; Sharma, R, 2014)
"Twelve patients with progressive dysphagia and video-fluoroscopic evidence of upper digestive tract stricture after head and neck cancer treatment were dilated by Maloney or Savory dilators followed by the application of mitomycin C (0."3.74Role of mitomycin in upper digestive tract stricture. ( Brodsky, MB; Day, TA; Gillespie, MB; Martin-Harris, B; Sharma, AK, 2007)
" We report the successful use of mitomycin C in a young boy in whom we could achieve ongoing relief of dysphagia after the unsuccessful long-term use of frequent endoscopic dilatations."3.74[Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy]. ( Fröhlich, T; Greess, H; Köhler, H, 2007)
"We describe a novel technique of endoluminal delivery and focused application of mitomycin-C to an esophageal stricture that avoids inadvertent topical application to adjacent mucosa."3.74Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery. ( Baird, R; Blair, GK; Heran, MK; Skarsgard, ED, 2008)
" The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures."3.73Mitomycin C prevents strictures in caustic esophageal burns in rats. ( Başaklar, AC; Demirtola, A; Dinçer, S; Gülen, S; Kale, N; Karabulut, R; Poyraz, A; Sönmez, K; Türkyilmaz, Z, 2005)
"Mitomycin C is an antiproliferative agent that has been used successfully as an adjunct treatment in ophthalmological procedures, in the management of laryngeal and tracheal stenosis, and more recently to prevent the recurrence of caustic esophageal strictures in children."3.73Mitomycin C: an alternative conservative treatment for refractory esophageal stricture in children? ( Fayoux, P; Gottrand, F; Guimber, D; Michaud, L; Turck, D; Uhlen, S; Vachin, F, 2006)
"To assess the role of mitomycin C (MMC) in the management of pharyngoesophageal stricture after total laryngopharyngectomy and free flap reconstruction."3.72Mitomycin C for the treatment of pharyngoesophageal stricture after total laryngopharyngectomy and microvascular free tissue reconstruction. ( Annino, DJ; Goguen, LA, 2003)
"Fifteen patients; choanal atresia in 5 patients, airway stenosis in 8 patients, hypopharyngeal stenosis in 1 patient, and esophageal stenosis in 1 patient."2.70The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe? ( Healy, GB; Jones, DT; Kenna, MA; McGill, TJ; Nuss, RC; Rahbar, R; Roberson, DW, 2002)
"Research on long-term use of mitomycin C (MC) for recurrent esophageal stenoses is limited."1.51Efficacy and Safety of the Local Application of Mitomycin C to Recurrent Esophageal Strictures in Children. ( Bridenne, M; Fayoux, P; Gottrand, F; Hauser, B; Lachaux, A; Lemale, J; Ley, D; Michaud, L; Rebouissoux, L; Viala, J, 2019)
"The median dysphagia score decreased from 2 (1 to 3) to 0 (0 to 2) after application (P<0."1.46Topical Mitomycin C Application Is Effective Even in Esophageal Strictures Resistant to Dilatation Therapy in Children. ( Divarci, E; Dokumcu, Z; Erdener, A; Kilic, O; Ozcan, C, 2017)
"Refractory esophageal stenosis (RES) is a major health problem in the pediatric population."1.43Management of refractory esophageal stenosis in the pediatric age. ( Alberca de Las Parras, F; Egea Valenzuela, J; Navalón Rubio, M, 2016)
"7 % high dose), while both TGF-β3 dosage groups showed no significant change (65."1.40Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures. ( Chak, A; Cipriano, C; Lash, RH; Marks, JM; Ponsky, JL; Schomisch, SJ; Wu, Y, 2014)
"Mitomycin-C 0."1.34Topical application of mitomycin-C in oesophageal strictures. ( Afzal, N; Cameron, D; Ibarguen-Secchia, E; Köhler, H; Lewindon, P; Lindley, KJ; Mahler, T; Rosseneu, S; Schwagten, K; Thomson, M; Yerushalmi, B, 2007)
"He consequently presented severe stenosis at the origin of the cervical esophagus that needed repeated balloon dilatations."1.34Topical application of mitomycin C in the treatment of esophageal and tracheobronchial stricture: a report of 2 cases. ( Adib, M; Daher, P; Georges, B; Georges, D; Riachy, E, 2007)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (35.71)29.6817
2010's26 (61.90)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Wishahy, AMK1
Seleim, H1
Qinawy, M1
Mohamed, W1
Mansour, O1
Abdullateef, KS1
Elkadi, R1
Raslan, H1
Arafa, A1
Yassin, T1
Ley, D1
Bridenne, M1
Gottrand, F2
Lemale, J1
Hauser, B1
Lachaux, A1
Rebouissoux, L1
Viala, J1
Fayoux, P3
Michaud, L3
Hoffman, RS1
Burns, MM1
Gosselin, S1
Divarci, E1
Kilic, O1
Dokumcu, Z1
Ozcan, C1
Erdener, A1
Madadi-Sanjani, O1
Zimmer, J1
Gosemann, JH1
Ure, BM1
Lacher, M2
Boehm, R1
Ghobrial, CM1
Eskander, AE1
Siersema, PD1
Nagaich, N1
Nijhawan, S1
Katiyar, P1
Sharma, R1
Rathore, M1
El-Asmar, KM3
Hassan, MA2
Abdelkader, HM2
Hamza, AF2
Wu, Y1
Schomisch, SJ1
Cipriano, C1
Chak, A1
Lash, RH1
Ponsky, JL1
Marks, JM1
Chapuy, L1
Pomerleau, M1
Faure, C1
Sweed, AS1
Fawaz, SA1
Ezzat, WF1
Sabri, SM1
Zhang, Y1
Wang, X1
Liu, L1
Chen, JP1
Fan, ZN1
Shub, MD1
Manfredi, MA1
Bartel, MJ1
Seeger, K1
Jeffers, K1
Clayton, D1
Wallace, MB1
Raimondo, M1
Woodward, TA1
Alberca de Las Parras, F1
Navalón Rubio, M1
Egea Valenzuela, J1
Deng, HY1
Wang, WP1
Lin, YD1
Chen, LQ1
Poincloux, L1
Rouquette, O1
Abergel, A1
Chiang, AL1
Abidi, WM1
Thompson, CC1
Spier, BJ1
Sawma, VA1
Gopal, DV1
Reichelderfer, M1
Türkyilmaz, Z2
Sönmez, K2
Karabulut, R2
Gülbahar, O1
Poyraz, A2
Sancak, B1
Başaklar, AC2
Chung, J1
Connolly, B1
Langer, J1
Marcon, M1
Temple, M1
Amaral, JG1
Heran, MKS1
Pham, TH1
Butterworth, S1
Robinson, A1
Berger, M1
Ure, B1
Machida, H1
Tominaga, K1
Minamino, H1
Sugimori, S1
Okazaki, H1
Yamagami, H1
Tanigawa, T1
Watanabe, K1
Watanabe, T1
Fujiwara, Y1
Arakawa, T1
Bustamante, TF1
Lourenção, PL1
Higa, KL1
Silva, AP1
Ortolan, EV1
Annino, DJ1
Goguen, LA1
Demirtola, A1
Gülen, S1
Dinçer, S1
Kale, N1
Uhlen, S2
Vachin, F1
Guimber, D1
Turck, D1
Olutoye, OO1
Shulman, RJ1
Cotton, RT1
Gillespie, MB1
Day, TA1
Sharma, AK1
Brodsky, MB1
Martin-Harris, B1
Rosseneu, S1
Afzal, N1
Yerushalmi, B1
Ibarguen-Secchia, E1
Lewindon, P1
Cameron, D1
Mahler, T1
Schwagten, K1
Köhler, H2
Lindley, KJ1
Thomson, M2
Fröhlich, T1
Greess, H1
Broto, J1
Gil-Vernet, JM1
Royo, G1
Cabañas, MJ1
Daher, P1
Riachy, E1
Georges, B1
Georges, D1
Adib, M1
Heran, MK1
Baird, R1
Blair, GK1
Skarsgard, ED1
Rahbar, R1
Jones, DT1
Nuss, RC1
Roberson, DW1
Kenna, MA1
McGill, TJ1
Healy, GB1
Afzal, NA1
Albert, D1
Thomas, AL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children[NCT04524897]Phase 420 participants (Anticipated)Interventional2020-12-01Not yet recruiting
Effectiveness Evaluation of Mixed Gel of Hydrocortisone and Aluminium Phosphate Preventing Endoscopic Submucosal Dissection Postoperative Stenosis for Patients With Early Esophageal Cancer Invading More Than 2/3 Esophageal Perimeter[NCT03165344]66 participants (Actual)Interventional2017-02-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for mitomycin and Esophageal Stricture

ArticleYear
Ingestion of Caustic Substances.
    The New England journal of medicine, 2020, 04-30, Volume: 382, Issue:18

    Topics: Acids; Adult; Alkalies; Burns, Chemical; Caustics; Child; Endoscopy, Digestive System; Esophageal Pe

2020
Therapy of caustic ingestion: new treatment considerations.
    Current opinion in pediatrics, 2015, Volume: 27, Issue:5

    Topics: Accidents; Alkylating Agents; Burns, Chemical; Caustics; Child; Child, Preschool; Dilatation; Esopha

2015
Endoscopic Management of Anastomotic Esophageal Strictures Secondary to Esophageal Atresia.
    Gastrointestinal endoscopy clinics of North America, 2016, Volume: 26, Issue:1

    Topics: Alkylating Agents; Deglutition Disorders; Dilatation; Esophageal Atresia; Esophageal Stenosis; Esoph

2016
Topical Mitomycin C application in the treatment of refractory benign esophageal strictures in adults and comprehensive literature review.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:9

    Topics: Aged; Alkylating Agents; Anastomosis, Surgical; Balloon Occlusion; Caustics; Constriction, Pathologi

2016
Can mitomycin facilitate endoscopic dilatation treatment of benign oesophageal stricture?
    Interactive cardiovascular and thoracic surgery, 2017, Volume: 24, Issue:1

    Topics: Antibiotics, Antineoplastic; Dilatation; Esophageal Stenosis; Esophagoscopy; Humans; Mitomycin

2017
Endoscopic treatment of benign esophageal strictures: a literature review.
    Expert review of gastroenterology & hepatology, 2017, Volume: 11, Issue:1

    Topics: Absorbable Implants; Dilatation; Esophageal Stenosis; Esophagoscopy; Humans; Injections, Intralesion

2017
Mitomycin C in the therapy of recurrent esophageal strictures: hype or hope?
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2012, Volume: 22, Issue:2

    Topics: Administration, Topical; Child; Child, Preschool; Drug-Eluting Stents; Endoscopy; Esophageal Stenosi

2012

Trials

5 trials available for mitomycin and Esophageal Stricture

ArticleYear
Topical Mitomycin C application for esophageal stricture: safe, precise, and novel endoscopic technique.
    Journal of pediatric surgery, 2013, Volume: 48, Issue:6

    Topics: Administration, Topical; Alkylating Agents; Burns, Chemical; Catheters; Child; Combined Modality The

2013
Topical mitomycin C application is effective in management of localized caustic esophageal stricture: a double-blinded, randomized, placebo-controlled trial.
    Journal of pediatric surgery, 2013, Volume: 48, Issue:7

    Topics: Administration, Topical; Burns, Chemical; Caustics; Child, Preschool; Double-Blind Method; Esophagea

2013
Topical mitomycin C can effectively alleviate dysphagia in children with long-segment caustic esophageal strictures.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2015, Volume: 28, Issue:5

    Topics: Administration, Topical; Alkylating Agents; Burns, Chemical; Caustics; Child, Preschool; Deglutition

2015
Locoregional mitomycin C injection for esophageal stricture after endoscopic submucosal dissection.
    Endoscopy, 2012, Volume: 44, Issue:6

    Topics: Aged; Carcinoma; Catheterization; Deglutition Disorders; Dissection; Esophageal Neoplasms; Esophagea

2012
The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe?
    Archives of otolaryngology--head & neck surgery, 2002, Volume: 128, Issue:4

    Topics: Administration, Topical; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Choanal At

2002

Other Studies

30 other studies available for mitomycin and Esophageal Stricture

ArticleYear
Short-term Effects of Mitomycin C Infiltration for Caustic Oesophageal Strictures in Children.
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:6

    Topics: Burns, Chemical; Child; Dilatation; Esophageal Stenosis; Esophagoscopy; Female; Humans; Male; Mitomy

2019
Efficacy and Safety of the Local Application of Mitomycin C to Recurrent Esophageal Strictures in Children.
    Journal of pediatric gastroenterology and nutrition, 2019, Volume: 69, Issue:5

    Topics: Administration, Mucosal; Adolescent; Antibiotics, Antineoplastic; Child; Child, Preschool; Esophagea

2019
Topical Mitomycin C Application Is Effective Even in Esophageal Strictures Resistant to Dilatation Therapy in Children.
    Surgical laparoscopy, endoscopy & percutaneous techniques, 2017, Volume: 27, Issue:5

    Topics: Administration, Topical; Adolescent; Alkylating Agents; Chemotherapy, Adjuvant; Child; Child, Presch

2017
Topical Mitomycin C Application in Pediatric Patients with Recurrent Esophageal Strictures-Report on Unfavorable Results.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2018, Volume: 28, Issue:6

    Topics: Administration, Topical; Adolescent; Alkylating Agents; Child; Child, Preschool; Combined Modality T

2018
Prospective study of the effect of topical application of Mitomycin C in refractory pediatric caustic esophageal strictures.
    Surgical endoscopy, 2018, Volume: 32, Issue:12

    Topics: Administration, Topical; Adolescent; Alkylating Agents; Burns, Chemical; Caustics; Child; Child, Pre

2018
How to Approach a Patient With Refractory or Recurrent Benign Esophageal Stricture.
    Gastroenterology, 2019, Volume: 156, Issue:1

    Topics: Algorithms; Clinical Decision-Making; Decision Support Techniques; Dilatation; Electrosurgery; Endos

2019
Mitomycin-C: 'a ray of hope' in refractory corrosive esophageal strictures.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2014, Volume: 27, Issue:3

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Burns, Chemical; Deglutition Disorders; Dilata

2014
Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures.
    Surgical endoscopy, 2014, Volume: 28, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Cicatrix; Disease Models, Animal; Dissection; Drug Therapy, Combin

2014
Topical mitomycin-C application in recurrent esophageal strictures after surgical repair of esophageal atresia.
    Journal of pediatric gastroenterology and nutrition, 2014, Volume: 59, Issue:5

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Child; Child, Preschool; Constriction, Patholo

2014
A prospective controlled study to assess the use of mitomycin C in improving the results of esophageal dilatation in post corrosive esophageal stricture in children.
    International journal of pediatric otorhinolaryngology, 2015, Volume: 79, Issue:1

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Burns, Chemical; Caustics; Child; Child, Presc

2015
Intramuscular injection of mitomycin C combined with endoscopic dilation for benign esophageal strictures.
    Journal of digestive diseases, 2015, Volume: 16, Issue:7

    Topics: Aged; Alkylating Agents; Anti-Inflammatory Agents; Combined Modality Therapy; Deglutition Disorders;

2015
Management of refractory esophageal stenosis in the pediatric age.
    Revista espanola de enfermedades digestivas, 2016, Volume: 108, Issue:10

    Topics: Adolescent; Antibiotics, Antineoplastic; Child; Child, Preschool; Drug Resistance; Esophageal Atresi

2016
Treatment of recurrent esophageal stricture with an insulated-tip electrosurgical knife and mitomycin C.
    Endoscopy, 2017, Volume: 49, Issue:S 01

    Topics: Administration, Topical; Aged, 80 and over; Combined Modality Therapy; Electrosurgery; Endoscopy, Ga

2017
Intralesional mitomycin C: successful treatment for benign recalcitrant esophageal stricture.
    Gastrointestinal endoscopy, 2009, Volume: 69, Issue:1

    Topics: Adult; Biopsy, Needle; Esophageal Stenosis; Esophagoscopy; Female; Follow-Up Studies; Humans; Immuno

2009
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
    Surgery, 2009, Volume: 145, Issue:2

    Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Mo

2009
Fluoroscopy-guided topical application of mitomycin-C in a case of refractory esophageal stricture.
    Journal of vascular and interventional radiology : JVIR, 2010, Volume: 21, Issue:1

    Topics: Administration, Topical; Child, Preschool; Chronic Disease; Esophageal Stenosis; Female; Fluoroscopy

2010
Use of a microporous polytetrafluoroethylene catheter balloon to treat refractory esophageal stricture: a novel technique for delivery of mitomycin C.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:4

    Topics: Administration, Topical; Alkylating Agents; Catheterization; Equipment Design; Esophageal Atresia; E

2011
The use of mitomycin C in caustic esophagitis in rats.
    Acta cirurgica brasileira, 2013, Volume: 28, Issue:2

    Topics: Animals; Burns, Chemical; Caustics; Dilatation; Disease Models, Animal; Esophageal Stenosis; Male; M

2013
Mitomycin C for the treatment of pharyngoesophageal stricture after total laryngopharyngectomy and microvascular free tissue reconstruction.
    The Laryngoscope, 2003, Volume: 113, Issue:9

    Topics: Adenocarcinoma; Administration, Topical; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy;

2003
Mitomycin C prevents strictures in caustic esophageal burns in rats.
    The Journal of surgical research, 2005, Volume: 123, Issue:2

    Topics: Alkalies; Animals; Antibiotics, Antineoplastic; Body Weight; Burns, Chemical; Disease Models, Animal

2005
Mitomycin C as an alternative to stent for conservative management of esophageal strictures in children.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 40, Issue:2

    Topics: Alkylating Agents; Dilatation; Esophageal Stenosis; Humans; Mitomycin; Stents; Treatment Outcome

2005
Mitomycin C: an alternative conservative treatment for refractory esophageal stricture in children?
    Endoscopy, 2006, Volume: 38, Issue:4

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Child; Child, Preschool; Dilatation; Esophagea

2006
Mitomycin C in the management of pediatric caustic esophageal strictures: a case report.
    Journal of pediatric surgery, 2006, Volume: 41, Issue:5

    Topics: Burns, Chemical; Esophageal Stenosis; Humans; Infant; Male; Mitomycin

2006
Role of mitomycin in upper digestive tract stricture.
    Head & neck, 2007, Volume: 29, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Degl

2007
Topical application of mitomycin-C in oesophageal strictures.
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 44, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Child, Preschool; Dilatation; Esophageal Stenosis

2007
[Topical mitomycin C treatment of a benign oesophageal stricture following caustic ingestion in a four-year-old boy].
    Zeitschrift fur Gastroenterologie, 2007, Volume: 45, Issue:3

    Topics: Administration, Topical; Burns, Chemical; Caustics; Child, Preschool; Deglutition Disorders; Esophag

2007
[Use of mitomycin C in esophageal stenosis].
    Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2007, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Child; Child, Preschool; Esophageal Stenosis; Female

2007
Topical application of mitomycin C in the treatment of esophageal and tracheobronchial stricture: a report of 2 cases.
    Journal of pediatric surgery, 2007, Volume: 42, Issue:9

    Topics: Administration, Topical; Anastomosis, Surgical; Bronchial Diseases; Child; Child, Preschool; Constri

2007
Topical mitomycin-C for recalcitrant esophageal strictures: a novel endoscopic/fluoroscopic technique for safe endoluminal delivery.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:5

    Topics: Administration, Topical; Adult; Burns, Chemical; Catheterization; Child, Preschool; Deglutition Diso

2008
A child with oesophageal strictures.
    Lancet (London, England), 2002, Mar-23, Volume: 359, Issue:9311

    Topics: Burns, Chemical; Caustics; Dilatation; Esophageal Stenosis; Female; Humans; Infant; Mitomycin

2002