Page last updated: 2024-11-06
mitomycin and Emesis
mitomycin has been researched along with Emesis in 23 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Between March 1994 and October 1997, 20 women and 19 men with primary extremity or limb girdle high-grade soft tissue sarcomas were registered to a study of preoperative ifosfamide, mitomycin, doxorubicin, cisplatin (IMAP) plus granulocyte macrophage-colony-stimulating factor (GM-CSF) followed by preoperative irradiation and subsequent limb-sparing surgery." | 9.10 | Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor. ( Buckner, JC; Edmonson, JH; Foo, ML; Gunderson, LL; Haddock, MG; Mahoney, MR; Maples, WJ; O'Connor, MI; Petersen, IA; Pritchard, DJ; Rock, MG; Shives, TC; Sim, FH; Stafford, SL, 2002) |
| "We have reported that an alternating regimen of bolus and continuous infusion 5-fluorouracil (FU) was superior to bolus FU in terms of response rate and progression-free survival in advanced colorectal cancer." | 9.09 | 5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer. ( Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D, 2001) |
| "To determine the incidence of nausea and vomiting and the antiemetic effect of ondansetron hydrochloride (OND) in patients with hepatocellular carcinoma treated with arterial chemo-embolization, we studied 59 patients with hepatocellular carcinoma who were treated with transcatheter arterial embolization (TAE) or lipiodolized transcatheter arterial infusion (L-TAI)." | 7.70 | Nausea and vomiting induced by arterial chemo-embolization in patients with hepatocellular carcinoma and the antiemetic effect of ondansetron hydrochloride. ( Abe, T; Hashimoto, Y; Kojima, A; Mori, M; Nagamine, T; Sohara, N; Takagi, H; Takahashi, H, 1999) |
| "To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted." | 7.68 | [A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990) |
| "Between March 1994 and October 1997, 20 women and 19 men with primary extremity or limb girdle high-grade soft tissue sarcomas were registered to a study of preoperative ifosfamide, mitomycin, doxorubicin, cisplatin (IMAP) plus granulocyte macrophage-colony-stimulating factor (GM-CSF) followed by preoperative irradiation and subsequent limb-sparing surgery." | 5.10 | Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor. ( Buckner, JC; Edmonson, JH; Foo, ML; Gunderson, LL; Haddock, MG; Mahoney, MR; Maples, WJ; O'Connor, MI; Petersen, IA; Pritchard, DJ; Rock, MG; Shives, TC; Sim, FH; Stafford, SL, 2002) |
| "We have reported that an alternating regimen of bolus and continuous infusion 5-fluorouracil (FU) was superior to bolus FU in terms of response rate and progression-free survival in advanced colorectal cancer." | 5.09 | 5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer. ( Aschele, C; Caroti, C; Cirillo, M; Cortesi, E; Frassineti, GL; Gallo, L; Grossi, F; Guglielmi, A; Labianca, R; Pessi, MA; Ravaioli, A; Recaldin, E; Sobrero, A; Testore, P; Turci, D, 2001) |
| "To determine the incidence of nausea and vomiting and the antiemetic effect of ondansetron hydrochloride (OND) in patients with hepatocellular carcinoma treated with arterial chemo-embolization, we studied 59 patients with hepatocellular carcinoma who were treated with transcatheter arterial embolization (TAE) or lipiodolized transcatheter arterial infusion (L-TAI)." | 3.70 | Nausea and vomiting induced by arterial chemo-embolization in patients with hepatocellular carcinoma and the antiemetic effect of ondansetron hydrochloride. ( Abe, T; Hashimoto, Y; Kojima, A; Mori, M; Nagamine, T; Sohara, N; Takagi, H; Takahashi, H, 1999) |
| "To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted." | 3.68 | [A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990) |
| "21 patients with metastatic breast cancer, refractory to conventional agents, were treated with a combination of BCNU, vincristine, mitomycin-C and prednisone given every 4 weeks." | 3.67 | Combination chemotherapy with BCNU, vincristine, mitomycin-C and prednisone in refractory breast carcinoma. A pilot study. ( Anderson, P; DiBella, NJ; Fink, K; Garfield, D; Murphy, J; Speer, J, 1984) |
| "As adverse reactions to the combination treatment by the digestive system, we observed the occurrence of nausea and vomiting in 15% of the cases who received FTP treatment consisting of 5-FU, toyomicin and prednisone, 25% of the cases who received MFU treatment consisting of MMC, 5-FU and ACNU, and in 64% of the cases who received PPQ treatment consisting of CDDP, Carboquone (CQ) and prednisone." | 3.67 | [Adverse reactions to carcinostatics and countermeasures]. ( Nakao, I, 1989) |
| " In conclusion, capecitabine can safely be combined with docetaxel (40 mg m(-2)) and mitomycin C (4 mg m(-2))." | 2.73 | Capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated tumours: results of an extended phase-I trial. ( Ernst, T; Gnad-Vogt, U; Hochhaus, A; Hofheinz, RD; Kripp, M; Lukan, N; Merx, K; Schultheis, B, 2007) |
| "N&V and leukopenia were the major side effects." | 2.68 | Salvage chemotherapy with PEM and long-CF regimen in CDDP refractory advanced head and neck cancer. ( Ichikawa, G; Inuyama, Y; Kawaida, M; Kohno, N; Ohnuma, T; Shirasaka, T, 1995) |
| "The morbidity of abdominal and pelvic SFP performed on a miscellaneous group of patients in our institute was analyzed and potential risk factors for adverse events were evaluated." | 1.38 | Complications and toxicity after abdominal and pelvic hypoxic stop-flow perfusion chemotherapy: incidence and assessment of risk factors. ( Askoxylakis, J; de Bree, E; Melissas, J; Metaxari, M; Michalakis, J; Romanos, J; Tsiftsis, DD; Tsogkas, J; Volakakis, E, 2012) |
Research
Studies (23)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (30.43) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| de Bree, E | 1 |
| Romanos, J | 1 |
| Tsogkas, J | 1 |
| Askoxylakis, J | 1 |
| Metaxari, M | 1 |
| Michalakis, J | 1 |
| Volakakis, E | 1 |
| Melissas, J | 1 |
| Tsiftsis, DD | 1 |
| Maruyama, S | 1 |
| Ernst, T | 1 |
| Merx, K | 1 |
| Gnad-Vogt, U | 1 |
| Lukan, N | 1 |
| Kripp, M | 1 |
| Schultheis, B | 1 |
| Hochhaus, A | 1 |
| Hofheinz, RD | 1 |
| DiBella, NJ | 1 |
| Garfield, D | 1 |
| Fink, K | 1 |
| Anderson, P | 1 |
| Speer, J | 1 |
| Murphy, J | 1 |
| Chahinian, AP | 1 |
| Green, G | 1 |
| Holland, JF | 1 |
| Meguro, S | 1 |
| Nagata, T | 1 |
| Yokoyama, K | 1 |
| Chinen, T | 1 |
| Kobayashi, T | 1 |
| Yamazaki, H | 1 |
| Kuraishi, Y | 1 |
| Abe, M | 1 |
| Isogai, Y | 1 |
| Kohno, N | 1 |
| Ichikawa, G | 1 |
| Shirasaka, T | 1 |
| Inuyama, Y | 1 |
| Kawaida, M | 1 |
| Ohnuma, T | 1 |
| Cullen, MH | 1 |
| Ferrigno, D | 1 |
| Buccheri, G | 1 |
| Morimoto, Y | 1 |
| Nakamura, M | 1 |
| Tamura, T | 1 |
| Kunii, T | 1 |
| Shimizu, K | 1 |
| Miyauchi, Y | 1 |
| Iop, A | 1 |
| Cartei, G | 1 |
| Vigevani, E | 1 |
| Clocchiatti, L | 1 |
| Mansutti, M | 1 |
| Sibau, AM | 1 |
| Han, JY | 1 |
| Kim, HK | 1 |
| Choi, BG | 1 |
| Moon, H | 1 |
| Hong, YS | 1 |
| Lee, KS | 1 |
| Sohara, N | 1 |
| Takagi, H | 1 |
| Abe, T | 1 |
| Hashimoto, Y | 1 |
| Kojima, A | 1 |
| Takahashi, H | 1 |
| Nagamine, T | 1 |
| Mori, M | 1 |
| Sobrero, A | 1 |
| Guglielmi, A | 1 |
| Cirillo, M | 1 |
| Recaldin, E | 1 |
| Frassineti, GL | 1 |
| Aschele, C | 1 |
| Ravaioli, A | 1 |
| Testore, P | 1 |
| Caroti, C | 1 |
| Gallo, L | 1 |
| Pessi, MA | 1 |
| Cortesi, E | 1 |
| Turci, D | 1 |
| Grossi, F | 1 |
| Labianca, R | 1 |
| Tsavaris, N | 1 |
| Kosmas, CH | 1 |
| Vadiaka, M | 1 |
| Kontos, A | 1 |
| Katsorida, M | 1 |
| Dimitrakopoulos, A | 1 |
| Zerai, A | 1 |
| Koufos, CH | 1 |
| Zhang, P | 1 |
| Feng, F | 1 |
| He, Y | 1 |
| Edmonson, JH | 1 |
| Petersen, IA | 1 |
| Shives, TC | 1 |
| Mahoney, MR | 1 |
| Rock, MG | 1 |
| Haddock, MG | 1 |
| Sim, FH | 1 |
| Maples, WJ | 1 |
| O'Connor, MI | 1 |
| Gunderson, LL | 1 |
| Foo, ML | 1 |
| Pritchard, DJ | 1 |
| Buckner, JC | 1 |
| Stafford, SL | 1 |
| Sakata, Y | 1 |
| Chiba, Y | 1 |
| Sato, T | 1 |
| Kimura, M | 1 |
| Fukushi, G | 1 |
| Matsukawa, M | 1 |
| Wada, K | 1 |
| Aoyama, H | 1 |
| Sawada, Y | 1 |
| Fukushi, M | 1 |
| Watanabe, A | 1 |
| Horio, Y | 1 |
| Minami, H | 1 |
| Shibagaki, T | 1 |
| Iwahara, T | 1 |
| Sakai, S | 1 |
| Shimokata, K | 1 |
| Yoshihara, T | 1 |
| Niimoto, M | 1 |
| Hirai, T | 1 |
| Miyoshi, Y | 1 |
| Ohtagaki, S | 1 |
| Hattori, T | 1 |
| Nakao, I | 1 |
| Shimizu, E | 1 |
| Kamei, T | 1 |
| Kimura, K | 1 |
| Mukai, J | 1 |
| Nakamura, Y | 1 |
| Kunishige, E | 1 |
| Fukuta, K | 1 |
| Tani, K | 1 |
| Sone, S | 1 |
| Ogura, T | 1 |
Reviews
1 review available for mitomycin and Emesis
| Article | Year |
|---|---|
[Complications of hepatic artery chemotherapy for liver metastases in colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cholangitis, Sclerosing | 2003 |
Trials
12 trials available for mitomycin and Emesis
| Article | Year |
|---|---|
Capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated tumours: results of an extended phase-I trial.
Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Di | 2007 |
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cy | 1984 |
Salvage chemotherapy with PEM and long-CF regimen in CDDP refractory advanced head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Admi | 1995 |
Mitomycin, ifosfamide, and cisplatin in non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcinoma, Non-Small-Cell | 1993 |
Is the MVP regimen less active than previously described? Results of a phase II study in advanced non-small cell lung cancer.
Topics: Adult; Aged; Alopecia; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Ph | 1996 |
[Treatment of postoperative nausea and vomiting with ondansetron in patients administered anti-neoplastic agents].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Female; | 1996 |
Quality of life (QOL) assessment of MIP (mitomycin, ifosfamide and cisplatin) chemotherapy in advanced non-small cell lung cancers (NSCLC).
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lun | 1998 |
5-fluorouracil modulated by leucovorin, methotrexate and mitomycin: highly effective, low-cost chemotherapy for advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Conjunctivitis; D | 2001 |
Efficacy of ondansentron treatment for acute emesis with different dosing schedules 8 vs 32 mg. A randomized study.
Topics: Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, | 2001 |
[Nasea injection in the prophylaxis of gastrointestinal reaction induced by chemotherapeutic agents].
Topics: Adolescent; Adult; Aged; Anorexia; Antiemetics; Benzimidazoles; Cisplatin; Digestive System; Female; | 2000 |
Chemotherapy, irradiation, and surgery for function-preserving therapy of primary extremity soft tissue sarcomas: initial treatment with ifosfamide, mitomycin, doxorubicin, and cisplatin plus granulocyte macrophage-colony-stimulating factor.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined | 2002 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
Other Studies
10 other studies available for mitomycin and Emesis
| Article | Year |
|---|---|
Complications and toxicity after abdominal and pelvic hypoxic stop-flow perfusion chemotherapy: incidence and assessment of risk factors.
Topics: Abdominal Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; | 2012 |
Combination chemotherapy with BCNU, vincristine, mitomycin-C and prednisone in refractory breast carcinoma. A pilot study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmu | 1984 |
[Phase I-II study of 7-N-(P-hydroxyphenyl)-mitomycin C (KW2083, M83)].
Topics: Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Hum | 1984 |
[Phase I study of KW2083 7-N-(p-hydroxyphenyl) mitomycin C].
Topics: Animals; Anorexia; Drug Evaluation; Humans; Mice; Mitomycin; Mitomycins; Nausea; Neoplasms; Vomiting | 1982 |
Mitomycin C, cisplatin, and 5-fluorouracil for advanced and/or recurrent head and neck squamous cell carcinomas.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; An | 1997 |
Nausea and vomiting induced by arterial chemo-embolization in patients with hepatocellular carcinoma and the antiemetic effect of ondansetron hydrochloride.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antiemetics; Antineoplastic Agents; Car | 1999 |
[A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis].
Topics: Administration, Oral; Adult; Aged; Alprazolam; Antineoplastic Combined Chemotherapy Protocols; Carci | 1990 |
[Combination chemotherapy with cis-diamminedichloroplatinum (CDDP) and other anticancer agents for patients with advanced esophageal cancer].
Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cispl | 1985 |
[Adverse reactions to carcinostatics and countermeasures].
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Chemical and Drug Indu | 1989 |
[Pilot combination phase II study of mitomycin C plus cisplatin for non-small cell lung cancer].
Topics: Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Sm | 1989 |