Page last updated: 2024-11-06

mitomycin and Eardrum Perforation

mitomycin has been researched along with Eardrum Perforation in 9 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine whether systemic glucocorticoid application, in combination with topical mitomycin or dexamethasone, prolongs the patency of a tympanic membrane perforation."7.73[Systemic corticoid application in combination with topical mitomycin or dexamethasone. Inhibition of wound healing after tympanic membrane perforation]. ( Hosemann, W; Kaftan, H, 2005)
" On the other side, tympanic membrane perforations treated with topical mitomycin C showed no evidence of closure."7.72The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation. ( Erdağ, TK; Güneri, A; Güneri, EA; Ikiz, AO; Ozkara, E; Sarioğlu, S; Tekin, S; Yilmaz, O, 2003)
"To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation."7.71Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001)
"The purpose of this study was to determine whether systemic glucocorticoid application, in combination with topical mitomycin or dexamethasone, prolongs the patency of a tympanic membrane perforation."3.73[Systemic corticoid application in combination with topical mitomycin or dexamethasone. Inhibition of wound healing after tympanic membrane perforation]. ( Hosemann, W; Kaftan, H, 2005)
" On the other side, tympanic membrane perforations treated with topical mitomycin C showed no evidence of closure."3.72The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation. ( Erdağ, TK; Güneri, A; Güneri, EA; Ikiz, AO; Ozkara, E; Sarioğlu, S; Tekin, S; Yilmaz, O, 2003)
"Only by additional partial excision of the handle of malleus followed by local application of mitomycin were we able to achieve a persistent tympanic membrane perforation."3.72[An improved animal model for chronic perforation of the tympanic membrane]. ( Beule, A; Hosemann, W; Junghans, D; Kaftan, H, 2004)
"To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation."3.71Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lou, ZC1
Wang, AY3
Liew, LJ3
Shen, Y3
Wang, JT3
von Unge, M3
Dilley, RJ3
Atlas, MD2
Güneri, EA1
Tekin, S1
Yilmaz, O1
Ozkara, E1
Erdağ, TK1
Ikiz, AO1
Sarioğlu, S1
Güneri, A1
Kaftan, H2
Hosemann, W2
Beule, A1
Junghans, D1
Evren, C1
Eken, M1
Ateş, G1
Bozkurt, Z1
Sanli, A1
O'Reilly, RC1
Goldman, SA1
Widner, SA1
Cass, SP1

Other Studies

9 other studies available for mitomycin and Eardrum Perforation

ArticleYear
Letter to the editor regarding: Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone.
    International journal of pediatric otorhinolaryngology, 2017, Volume: 100

    Topics: Animals; Dexamethasone; Middle Ear Ventilation; Mitomycin; Rats; Tympanic Membrane; Tympanic Membran

2017
In response to the letter to the editor regarding: Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone.
    International journal of pediatric otorhinolaryngology, 2017, Volume: 100

    Topics: Animals; Dexamethasone; Middle Ear Ventilation; Mitomycin; Rats; Tympanic Membrane; Tympanic Membran

2017
Searching for a rat model of chronic tympanic membrane perforation: Healing delayed by mitomycin C/dexamethasone but not paper implantation or iterative myringotomy.
    International journal of pediatric otorhinolaryngology, 2015, Volume: 79, Issue:8

    Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease Models

2015
Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone.
    International journal of pediatric otorhinolaryngology, 2016, Volume: 80

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease

2016
The effects of hyaluronic acid, epidermal growth factor, and mitomycin in an experimental model of acute traumatic tympanic membrane perforation.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2003, Volume: 24, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Anti-Ulcer Agents; Antibiotics, Antineoplastic; Epidermal Growth Fa

2003
[An improved animal model for chronic perforation of the tympanic membrane].
    HNO, 2004, Volume: 52, Issue:8

    Topics: Administration, Topical; Animals; Chronic Disease; Disease Models, Animal; Male; Microsurgery; Mitom

2004
[Systemic corticoid application in combination with topical mitomycin or dexamethasone. Inhibition of wound healing after tympanic membrane perforation].
    HNO, 2005, Volume: 53, Issue:9

    Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anti-Inflammatory

2005
[The effect of topical mitomycin-C application before or after incisional myringotomy on patency times of guinea pig tympanic membrane perforations].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2007, Volume: 17, Issue:2

    Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Guinea Pigs;

2007
Creating a stable tympanic membrane perforation using mitomycin C.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2001, Volume: 124, Issue:1

    Topics: Alkylating Agents; Animals; Chronic Disease; Disease Models, Animal; Male; Middle Ear Ventilation; M

2001