mitomycin has been researched along with Disease Models, Animal in 180 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to investigate the effect of mitomycin C on reducing endometrial fibrosis for IUA." | 7.96 | The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion. ( Shen, X; Sun, C; Wang, W; Xu, F; Xu, X; Zheng, J, 2020) |
| "To find safer and more effective drugs than mitomycin C to prevent conjunctival fibrosis in a rabbit model." | 7.91 | Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival fibrosis. ( Han, GS; Jung, HS; Kim, ES; Kim, JY; Suh, LH; Tchah, H; Yoon, SY, 2019) |
| " The triamcinolone + mitomycin C acetate group presented better indices as for the maximum bleb height and vascularization of the bleb central area (p=0." | 7.88 | Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study. ( Araújo, ID; Cronemberger, S; Rangel, HMDA; Rolim, HT; Vidigal, P, 2018) |
| "To determine if sequential treatment with Bevacizumab (Avastin), a monoclonal, VEGF antibody that blocks angiogenesis; Saratin, a 12 kD polypeptide with anti-inflammatory and anti-thrombotic properties; and Ilomastat, a matrix metalloproteinase (MMP) inhibitor, prolongs bleb life following glaucoma filtration surgery (GFS) in a rabbit model." | 7.81 | Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model. ( Levine, MA; Lukowski, ZL; Martorana, GM; Meyers, CA; Min, J; Schaefer, JL; Schultz, GS; Sherwood, MB, 2015) |
| "To analyze the urothelial responses to mitomycin C treatment after urethral injury in rats, as the urothelium might play a role in the pathogenesis of urethral stricture." | 7.81 | Morphological effects of mitomycin C on urothelial responses to experimentally-induced urethral stricture in rats. ( Chang, IY; Han, M; Huh, JS; Kim, JN; Kim, SO; Maeng, YH; Yoon, SP, 2015) |
| "To compare the effects of silver nanoparticles (AgNPs) and mitomycin C (MMC) on intraocular pressure (IOP) and external, histologic, and immunohistochemical bleb characteristics in a rabbit model of filtration surgery." | 7.79 | Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery. ( Butler, MR; Chevez-Barrios, P; Frankfort, BJ; Orengo-Nania, S; Prospero Ponce, CM; Weinstock, YE, 2013) |
| "The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC)." | 7.78 | Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery. ( Arslan, S; Aydemir, O; Dağlı, AF; Güler, M, 2012) |
| "We comparative effects of mitomycin-c and heparin which have different mechanism of action in a minimal invasive corrosive esophagitis model which was formed by NaOH 40%." | 7.77 | Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats. ( Pabuscu, E; Sen, S; Senturk, E; Unsal, C, 2011) |
| "To investigate whether topical administration of pirfenidone eye drops could be used to prevent postoperative scarring in a rabbit model of experimental glaucoma filtration surgery." | 7.77 | Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. ( Lin, X; Sun, G; Wu, K; Yu, M; Zhong, H, 2011) |
| "These results suggest that topical mitomycin is not effective for avoiding tracheal stenosis and may provoke the opposite effect if the dose is not carefully selected." | 7.74 | Effect of mitomycin in the surgical treatment of tracheal stenosis. ( González Bombardiere, S; Guilemany Toste, JM; Iñiguez-Cuadra, M; Iñiguez-Cuadra, R; Iñiguez-Sasso, R; Jofré Pavez, D; San Martín Prieto, J; Zúñiga Erranz, S, 2008) |
| "To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS)." | 7.73 | Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery. ( Khaw, PT; Mead, AL; Wong, TT, 2005) |
| "To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation." | 7.71 | Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001) |
| "Fanconi anemia (FA) is a genetic disorder defined by cellular hypersensitivity to DNA cross-linking agents, such as mitomycin C (MMC)." | 7.70 | Assessment of mitomycin C sensitivity in Fanconi anemia complementation group C gene (Fac) knock-out mouse cells. ( Demuth, I; Digweed, M; Liu, JM; Otsuki, T; Wang, J, 1998) |
| "To investigate the therapeutic potential of mitomycin C (MMC) in the management of proliferative vitreoretinopathy (PVR), antiproliferative effect of MMC on rabbit retinal pigment epithelial (RPE) cells, its intraocular toxicity, and its preventive effect on experimental PVR were investigated." | 7.69 | Antiproliferative effect of mitomycin C on experimental proliferative vitreoretinopathy in rabbits. ( Chung, H; Yu, HG, 1997) |
| "To investigate the participation of endothelial cells in glomerulosclerosis, the study was performed in serum sickness nephritis (SSN) with administration of mitomycin C (MMC)." | 7.69 | Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C. ( Chowdhury, AK, 1996) |
| "In this study, an experimental model of glaucoma filtration surgery was used to evaluate the clinical and histologic effects of a single intraoperative topical application of mitomycin C." | 7.68 | Effect of topical mitomycin C on glaucoma filtration surgery in monkeys. ( Dorman-Pease, ME; Jampel, HD; Pasquale, LR; Quigley, HA; Thibault, D, 1992) |
| "In the rat bladder cancer model, IVI of chidamide plus mitomycin C reduced tumor burden (Ki67 index) to a greater extent than either drug alone." | 5.72 | Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model. ( Chang, YC; Chen, SL; Sung, WW; Wang, SC; Wu, YC; Yu, CY, 2022) |
| "There was intensive epineural scar formation in the control group." | 5.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "All patients displayed squamous anal cancer and were treated with MMC alone or MMC plus 5-fluoruracil." | 5.42 | Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models. ( Antigny, F; Chaumais, MC; Cottin, V; Dorfmüller, P; Girerd, B; Godinas, L; Günther, S; Hautefort, A; Humbert, M; Jaïs, X; Montani, D; Perros, F; Ranchoux, B; Raymond, N; Savale, L; Simonneau, G; Sitbon, O, 2015) |
| "Mitomycin-C was administered to the injured urethra in the form of irrigation for 5 min." | 5.32 | Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture. ( Ayyildiz, A; Caydere, M; Erol, D; Germiyanoglu, C; Gülerkaya, B; Nuhoglu, B; Ustün, H, 2004) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS)." | 4.12 | Inhibitory Effects of 3',4'-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts. ( Chan, EC; Edgley, AJ; Fan Gaskin, JC; Kong, RCK; Peshavariya, HM; Shah, MH, 2022) |
| " The purpose of this study was to investigate the effect of mitomycin C on reducing endometrial fibrosis for IUA." | 3.96 | The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion. ( Shen, X; Sun, C; Wang, W; Xu, F; Xu, X; Zheng, J, 2020) |
| "To find safer and more effective drugs than mitomycin C to prevent conjunctival fibrosis in a rabbit model." | 3.91 | Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival fibrosis. ( Han, GS; Jung, HS; Kim, ES; Kim, JY; Suh, LH; Tchah, H; Yoon, SY, 2019) |
| " The triamcinolone + mitomycin C acetate group presented better indices as for the maximum bleb height and vascularization of the bleb central area (p=0." | 3.88 | Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study. ( Araújo, ID; Cronemberger, S; Rangel, HMDA; Rolim, HT; Vidigal, P, 2018) |
| "SFN was compared with several commonly used chemotherapy drugs, including mitomycin (MMC) and pirarubicin (THP) for anticancer effects on the bladder cancer cell lines T24, BTT, and BIU-87 and SFN half inhibitory concentrations (IC50) were determined after 48 hours of treatment." | 3.83 | Evaluation of Su Fu'ning Lotion's Inhibitory Effects on Bladder Cancer Cells In Vitro and In Vivo by Intravesical Instillation. ( Ren, L; Wang, J; Yang, X; Zhang, H; Zhao, L, 2016) |
| "To analyze the urothelial responses to mitomycin C treatment after urethral injury in rats, as the urothelium might play a role in the pathogenesis of urethral stricture." | 3.81 | Morphological effects of mitomycin C on urothelial responses to experimentally-induced urethral stricture in rats. ( Chang, IY; Han, M; Huh, JS; Kim, JN; Kim, SO; Maeng, YH; Yoon, SP, 2015) |
| "To determine the optimum administration route of bevacizumab after glaucoma filtering surgery (GFS) and to investigate whether a reduced dose of mitomycin-C (MMC) in combination with bevacizumab could improve surgical outcome with a reduced incidence of side-effects." | 3.81 | Complementary effects of bevacizumab and MMC in the improvement of surgical outcome after glaucoma filtration surgery. ( Moons, L; Stalmans, I; Van Bergen, T; Vandewalle, E, 2015) |
| "To determine if sequential treatment with Bevacizumab (Avastin), a monoclonal, VEGF antibody that blocks angiogenesis; Saratin, a 12 kD polypeptide with anti-inflammatory and anti-thrombotic properties; and Ilomastat, a matrix metalloproteinase (MMP) inhibitor, prolongs bleb life following glaucoma filtration surgery (GFS) in a rabbit model." | 3.81 | Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model. ( Levine, MA; Lukowski, ZL; Martorana, GM; Meyers, CA; Min, J; Schaefer, JL; Schultz, GS; Sherwood, MB, 2015) |
| "This study was undertaken to evaluate the efficacy of co-treatment with suberoylanilide hydroxamic acid (SAHA) and mitomycin-C (MMC) on corneal fibrosis in an in-vivo model." | 3.80 | The efficacy of co-treatment with suberoylanilide hydroxamic acid and mitomycin C on corneal scarring after therapeutic keratectomy: an animal study. ( Kim, SW; Park, WC; Woo, JE; Yoo, YH, 2014) |
| "The aim of this study was to determine the efficacy of epigallocatechin-3-gallate (EGCG) (Polyphenon E®) in comparison with mitomycin C (MMC) to prevent tumor cell implantation/growth in an animal model of superficial bladder cancer and search for possible mechanism(s) of action." | 3.80 | Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model. ( Jankun, J; Keck, RW; Selman, SH, 2014) |
| "To compare the effects of silver nanoparticles (AgNPs) and mitomycin C (MMC) on intraocular pressure (IOP) and external, histologic, and immunohistochemical bleb characteristics in a rabbit model of filtration surgery." | 3.79 | Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery. ( Butler, MR; Chevez-Barrios, P; Frankfort, BJ; Orengo-Nania, S; Prospero Ponce, CM; Weinstock, YE, 2013) |
| "The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC)." | 3.78 | Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery. ( Arslan, S; Aydemir, O; Dağlı, AF; Güler, M, 2012) |
| "To investigate whether topical administration of pirfenidone eye drops could be used to prevent postoperative scarring in a rabbit model of experimental glaucoma filtration surgery." | 3.77 | Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. ( Lin, X; Sun, G; Wu, K; Yu, M; Zhong, H, 2011) |
| "We comparative effects of mitomycin-c and heparin which have different mechanism of action in a minimal invasive corrosive esophagitis model which was formed by NaOH 40%." | 3.77 | Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats. ( Pabuscu, E; Sen, S; Senturk, E; Unsal, C, 2011) |
| "The protective effects of topical mitomycin-C (MMC) have been well documented for tracheal stenosis; however, to the best of our knowledge, the use of heparin as an anti-inflammatory agent to support wound healing in upper airway surgery was not studied before." | 3.75 | Topical heparin: a promising agent for the prevention of tracheal stenosis in airway surgery. ( Barutca, S; Derincegoz, OO; Derinceoz, OO; Meteoglu, I; Ogurlu, M; Sen, S, 2009) |
| " In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
| "The recurrence rate of superficial bladder cancer is still high even the patients received postoperative intravesical infusion of chemotherapeutic drugs, such as mitomycin C (MMC)." | 3.74 | [Establishment and application of an orthotopic murine bladder cancer model]. ( Cen, JN; Chen, JH; He, J; Hou, JQ; Wen, DG; Yang, SM, 2007) |
| "These results suggest that topical mitomycin is not effective for avoiding tracheal stenosis and may provoke the opposite effect if the dose is not carefully selected." | 3.74 | Effect of mitomycin in the surgical treatment of tracheal stenosis. ( González Bombardiere, S; Guilemany Toste, JM; Iñiguez-Cuadra, M; Iñiguez-Cuadra, R; Iñiguez-Sasso, R; Jofré Pavez, D; San Martín Prieto, J; Zúñiga Erranz, S, 2008) |
| "To investigate whether cultured autologous fibroblasts injected into the subconjunctival space of rabbit may be used as a new treatment modality for conjunctival and subconjunctival atrophy caused by mitomycin C (MMC)." | 3.73 | Injection of cultured autologous fibroblasts into the subconjunctival space of rabbits treated with mitomycin C. ( Hwang, JM; Kee, C, 2006) |
| "To evaluate influence of mitomycin C on fibrosis in temporomandibular joints of rabbits with mandibular traction." | 3.73 | Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint. ( Aydin, E; Ozdemir, BH; Uckan, S; Uyar, P, 2005) |
| "To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS)." | 3.73 | Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery. ( Khaw, PT; Mead, AL; Wong, TT, 2005) |
| " The purpose of this study was to investigate the effectiveness of Mitomycin C (MMC), which inhibits fibroblastic proliferation in preventing caustic esophageal strictures." | 3.73 | Mitomycin C prevents strictures in caustic esophageal burns in rats. ( Başaklar, AC; Demirtola, A; Dinçer, S; Gülen, S; Kale, N; Karabulut, R; Poyraz, A; Sönmez, K; Türkyilmaz, Z, 2005) |
| "Colitis was induced by administration of 5% dextran sodium sulphate in the drinking water or by one intraperitoneal injection of mitomycin C, 3." | 3.73 | Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat. ( Hare, K; Hartmann, B; Kissow, H; Poulsen, SS; Thim, L, 2005) |
| "Only by additional partial excision of the handle of malleus followed by local application of mitomycin were we able to achieve a persistent tympanic membrane perforation." | 3.72 | [An improved animal model for chronic perforation of the tympanic membrane]. ( Beule, A; Hosemann, W; Junghans, D; Kaftan, H, 2004) |
| "To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation." | 3.71 | Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001) |
| "Fanconi anemia (FA) is a human autosomal recessive cancer susceptibility disorder characterized by cellular sensitivity to mitomycin C and ionizing radiation." | 3.71 | Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. ( D'Andrea, AD; Hays, T; Kuang, Y; Lu, N; Montes De Oca, R; Moreau, L; Seed, B; Yang, Y, 2001) |
| "Fanconi anemia (FA) is a genetic disorder defined by cellular hypersensitivity to DNA cross-linking agents, such as mitomycin C (MMC)." | 3.70 | Assessment of mitomycin C sensitivity in Fanconi anemia complementation group C gene (Fac) knock-out mouse cells. ( Demuth, I; Digweed, M; Liu, JM; Otsuki, T; Wang, J, 1998) |
| "5-(2-Pyridylsulfonyl)-2-thiazolamine (2) was effective both in mitomycin C (MMC)-induced thrombocytopenia and in an animal model of idiopathic thrombocytopenic purpura (ITP)." | 3.70 | Synthesis and effects of novel thiazole derivatives against thrombocytopenia. ( Manda, T; Matsuo, M; Nishigaki, F; Ogino, T; Sawada, M; Seki, N; Sudo, Y; Tsuji, K, 1998) |
| "To investigate the participation of endothelial cells in glomerulosclerosis, the study was performed in serum sickness nephritis (SSN) with administration of mitomycin C (MMC)." | 3.69 | Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C. ( Chowdhury, AK, 1996) |
| "Administration of subconjunctival 5-fluorouracil (5-FU) and topical mitomycin-C (MMC) has been shown to improve the success rate of glaucoma-filtering surgery." | 3.69 | A novel MMC-loaded pHEMA drainage device for the treatment of glaucoma: in vitro and in vivo studies. ( Akata, RF; Gökçe, M; Kiremitçi-Gümüşderelioglu, M, 1996) |
| "A pars plana vitrectomy was performed in 12 eyes, and two neurosensory retinal detachments per eye were created by injecting 10(-3) mg/ml mitomycin C and 0." | 3.69 | Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration. ( Del Priore, LV; Hornbeck, R; Jones, Z; Kaplan, HJ; Swinn, M, 1996) |
| "To investigate the therapeutic potential of mitomycin C (MMC) in the management of proliferative vitreoretinopathy (PVR), antiproliferative effect of MMC on rabbit retinal pigment epithelial (RPE) cells, its intraocular toxicity, and its preventive effect on experimental PVR were investigated." | 3.69 | Antiproliferative effect of mitomycin C on experimental proliferative vitreoretinopathy in rabbits. ( Chung, H; Yu, HG, 1997) |
| "Rabbits undergoing full-thickness glaucoma filtering surgery were exposed for 5 minutes to one of three intraoperative treatments: (1) distilled water; (2) fluorouracil, 50 mg/mL; or (3) mitomycin C, 0." | 3.68 | Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C. ( Doyle, JW; Grierson, I; Khaw, PT; McGorray, S; Schultz, G; Sherwood, MB, 1993) |
| "In this study, an experimental model of glaucoma filtration surgery was used to evaluate the clinical and histologic effects of a single intraoperative topical application of mitomycin C." | 3.68 | Effect of topical mitomycin C on glaucoma filtration surgery in monkeys. ( Dorman-Pease, ME; Jampel, HD; Pasquale, LR; Quigley, HA; Thibault, D, 1992) |
| "We investigated the antitumor effects of intratumoral (IT) injection of mitomycin-C (MMC), 5-fluorouracil (5FU), adriamycin (ADR), cisplatin (CDDP), streptozotocin (STZ), and interleukin-2 (IL-2) on well-differentiated pancreatic ductal adenocarcinoma (WD PaCa), a solid tumor model in the Syrian golden hamster." | 3.68 | Experimental study on multidisciplinary treatment of pancreatic cancer. ( Makino, I; Moriai, T; Takeba, T, 1990) |
| "We investigated the effectiveness of intravesically administered drugs on the tumor incidence and tumor size in a FANFT-induced animal model for bladder cancer." | 3.66 | Single and sequential combination intravesical chemotherapy of murine bladder cancer. ( McCallum, LW; Murphy, WM; Nissenkorn, I; Soloway, MS, 1982) |
| "In the rat bladder cancer model, IVI of chidamide plus mitomycin C reduced tumor burden (Ki67 index) to a greater extent than either drug alone." | 1.72 | Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model. ( Chang, YC; Chen, SL; Sung, WW; Wang, SC; Wu, YC; Yu, CY, 2022) |
| "Treatment of tracheal stenosis is occasionally performed in combination with wound healing modulators to manipulate new extracellular matrix (ECM) formation and prevent fibrosis." | 1.56 | Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection. ( Baltazares-Lipp, M; Baltazares-Lipp, ME; Gaxiola-Gaxiola, M; González-González, AI; Hernández-Jiménez, C; Iñiguez-García, MA; Jasso-Victoria, R; Luna-Flores, A; Olmos-Zuñiga, JR; Silva-Martínez, M; Solis-Alanis, N; Vázquez-Minero, JC, 2020) |
| "Mitomycin C (MMC) has been demonstrated to have significant inhibitory effects on epidural scar." | 1.46 | MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy. ( Cao, X; Geng, D; Jiang, L; Liu, J; Qin, J; Shen, X; Wang, B; Wu, T; Xie, H; Yu, C; Yuan, T, 2017) |
| " Nanoparticle-based drug combination has been shown to mitigate the problems encountered by free drug combination therapy." | 1.46 | Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice. ( Chen, K; Cheng, J; Lai, P; Pang, KS; Rauth, AM; Wu, XY; Zhang, RX; Zhang, T, 2017) |
| " Furthermore, SAHA dosing did not compromise corneal endothelial phenotype, density, or function in rabbit eyes, whereas MMC application did (P < ." | 1.46 | Efficacy and Safety Comparison Between Suberoylanilide Hydroxamic Acid and Mitomycin C in Reducing the Risk of Corneal Haze After PRK Treatment In Vivo. ( Anumanthan, G; Gupta, S; Hamm, CW; Hesemann, NP; Mohan, RR; Sharma, A; Waggoner, M, 2017) |
| "There was intensive epineural scar formation in the control group." | 1.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "All patients displayed squamous anal cancer and were treated with MMC alone or MMC plus 5-fluoruracil." | 1.42 | Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models. ( Antigny, F; Chaumais, MC; Cottin, V; Dorfmüller, P; Girerd, B; Godinas, L; Günther, S; Hautefort, A; Humbert, M; Jaïs, X; Montani, D; Perros, F; Ranchoux, B; Raymond, N; Savale, L; Simonneau, G; Sitbon, O, 2015) |
| "Furthermore, MMC alone enhanced genomic instability, but MMC combined with AET attenuated the extent of genomic instability in primary VX2 tumor tissue." | 1.42 | Tumor growth and metastasis can be inhibited by maintaining genomic stability in cancer cells. ( Bei, J; Feng, F; Feng, Q; Hong, J; Hu, W; Kang, T; Liang, Y; Peng, R; Sang, Y; Xu, M; Zeng, Y, 2015) |
| "7 % high dose), while both TGF-β3 dosage groups showed no significant change (65." | 1.40 | Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures. ( Chak, A; Cipriano, C; Lash, RH; Marks, JM; Ponsky, JL; Schomisch, SJ; Wu, Y, 2014) |
| " Diffuse colorectal carcinomatosis was generated in mice prior to intraperitoneal lavage with mitomycin C (MMC) at clinically comparable dosing for variable lengths of time." | 1.39 | The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis. ( Attwood, K; Camoriano, M; Francescutti, V; Haslinger, M; Kane, JM; Kim, M; Rivera, L; Seshadri, M; Skitzki, JJ, 2013) |
| "Mitomycin-C has been in clinical use primarily as a chemotherapeutic agent and is well known for antifibrotic properties." | 1.39 | The effect of mitomycin-C in reducing pericardial adhesion after cardiac surgery in rabbits. ( Akkaya, IO; Aksoy, ON; Alpay, MF; Bayrak, R; Cakir, O; Colak, N; Nazli, Y; Tasoglu, I, 2013) |
| "The frequency of LT1009 dosage was determined initially using an enzyme-linked immunosorbent assay assay measuring LT1009 eye tissue retention in 6 New Zealand White rabbits." | 1.39 | Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model. ( Beattie, AR; Levine, MA; Lukowski, ZL; Meyers, CA; Min, J; Samuelson, DA; Schultz, GS; Sherwood, MB; Stoller, G, 2013) |
| "Human and murine colon cancer cell lines were subjected to mild hyperthermia (40-42°C), and treated with chemotherapy, similar to clinical protocols." | 1.38 | New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models. ( Clavien, PA; Gertsch, P; Graf, R; Humar, B; Jang, JH; Lehmann, K; Oberkofler, CE; Rickenbacher, A; von Boehmer, L; Vonlanthen, R, 2012) |
| " Thus, appropriately dosed Cy may provide a suitable conditioning regimen for FA patients undergoing HSC gene therapy." | 1.38 | Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities. ( Adair, JE; Beard, BC; Becker, PS; Chien, S; Fang, M; Kiem, HP; Taylor, JA; Trobridge, GD; Wohlfahrt, ME; Zhao, X, 2012) |
| "Tracheal stenosis was most significant for the bioabsorbable helical stents, followed by the control group without stent, the group of bioabsorbable tubular stents, and then the silicone stents." | 1.37 | A novel bioabsorbable drug-eluting tracheal stent. ( Boey, FY; Ng, AH; Trasti, SL; Venkatraman, SS; Wee, AL; Yee Lim, LH; Zhu, GH, 2011) |
| "Mitomycin C and EGCG were studied for their in vitro and in vivo effects." | 1.37 | A comparative study of the inhibiting effects of mitomycin C and polyphenolic catechins on tumor cell implantation/growth in a rat bladder tumor model. ( Keck, RW; Selman, SH, 2011) |
| "Surgical cytoreduction of peritoneal surface malignancy of colorectal origin in combination with hyperthermic intraoperative peritoneal chemotherapy (HIPEC) has become an established treatment approach." | 1.36 | Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model. ( Atanassow, V; Braumann, C; Caldenas, S; Hartmann, J; Kilian, M; Makareinis, A; Raue, W; Schwenk, W, 2010) |
| "Acute airway obstruction may occur in MMC-treated rabbits with tracheal wounds." | 1.34 | Benefits and risks of mitomycin use in the traumatized tracheal mucosa. ( Kim, DH; Kim, KH; Park, CI; Rha, KS; Roh, JL; Sung, MW, 2007) |
| "Hydroxyproline (HP) levels were significantly higher in control group than all other groups (P < 0." | 1.34 | Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions. ( Ariturk, E; Bernay, F; Bicakci, U; Kilicoglu-Aydin, B; Rizalar, R; Tander, B, 2007) |
| "Mitomycin C is a chemotherapeutic agent known to suppress fibroblast proliferation." | 1.34 | The effect of topical mitomycin C on full-thickness burns. ( Dick, E; Helling, ER; Lyons, RC; Tennyson, H; Wiseman, J, 2007) |
| "To assess the effect of transcatheter arterial chemoembolization (TACE) combined with laser-induced thermotherapy (LITT) for treatment of liver metastases in an animal model." | 1.33 | Liver metastases in rats: chemoembolization combined with interstitial laser ablation for treatment. ( Bechstein, WO; Khan, MF; Maataoui, A; Mack, MG; Oppermann, E; Qian, J; Roozru, M; Schmidt, S; Vogl, TJ, 2005) |
| "There was a significant risk of acute airway obstruction from delayed wound healing in rabbits that received subglottic laser wounding and MMC treatment." | 1.33 | Can mitomycin C really prevent airway stenosis? ( Lee, YW; Park, CI; Roh, JL, 2006) |
| "Two additional filtering blebs were treated with balanced saline solution (BSS), two received mitomycin-C (MMC) (0." | 1.33 | A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis). ( Sherwood, MB, 2006) |
| "Mitomycin C treatment induces apoptosis of keratocytes and myofibroblasts, but the predominate effect in inhibiting or treating haze appears to be at the level of blocked replication of keratocytes or other progenitor cells of myofibroblasts." | 1.33 | Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. ( Gupta, PC; Mohan, RR; Netto, MV; Sharma, A; Sinha, S; Wilson, SE, 2006) |
| "Mitomycin C (MMC) treatment produces genotoxic stress and exerts various biologic effects on cell function." | 1.32 | Permanent acceptance of mitomycin C-treated islet allograft. ( Gotoh, M; Gunji, T; Ise, K; Matsuyama, S; Saito, T; Sato, Y, 2003) |
| "In advanced gastric cancer, peritoneal recurrence is the main cause of death after curative surgical resection." | 1.32 | Application of molecular diagnosis for detection of peritoneal micrometastasis and evaluation of preoperative chemotherapy in advanced gastric carcinoma. ( Azama, T; Fujiwara, Y; Ishii, T; Monden, M; Mori, T; Sugita, Y; Takiguchi, S; Taniguchi, K; Yamazaki, K; Yano, M; Yasuda, T, 2004) |
| "Here we show that ethanol withdrawal symptoms were completely absent in cannabinoid CB1 receptor-deficient mice, although acute effects of ethanol and ethanol tolerance and preference were basically normal." | 1.32 | A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking. ( Bilkei-Gorzo, A; Michel, K; Palkovits, M; Racz, I; Toth, ZE; Zimmer, A, 2003) |
| "Mitomycin-C was administered to the injured urethra in the form of irrigation for 5 min." | 1.32 | Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture. ( Ayyildiz, A; Caydere, M; Erol, D; Germiyanoglu, C; Gülerkaya, B; Nuhoglu, B; Ustün, H, 2004) |
| "To introduce an animal model of hepatocellular carcinoma (HCC) in ACI-rats, and to evaluate the therapeutic effects of Poly-lactide-co-glycolide (Plcg) -microspheres in the transarterial chemoembolization (TACE) in this model, as well the value of this model in the experiments of interventional therapy." | 1.32 | Application of poly-lactide-co-glycolide-microspheres in the transarterial chemoembolization in an animal model of hepatocellular carcinoma. ( Claussen, C; Eul, T; Graepler, F; Huppert, P; Pereira, P; Qian, J; Truebenbach, J; Wiemann, G, 2003) |
| "Mitomycin C was one of the first chemotherapeutic agents to be shown to have preferential cytotoxicity toward hypoxic cells in vitro." | 1.31 | Effects of mitomycin C on the oxygenation and radiosensitivity of murine and human tumours in mice. ( Durand, RE; LePard, NE, 2000) |
| "Mitomycin C has an adjunct effect in laser myringotomy in prolonging the patency rate of myringotomy on rats." | 1.31 | Topical use of mitomycin C in laser myringotomy: an experimental study in rats. ( Yucel, OT, 2000) |
| "In 3 dogs, recurrence was established after surgical lysis." | 1.31 | Prevention of anterior glottic restenosis in a canine model with topical mitomycin-C. ( Huang, S; Reinisch, L; Sanders, D; Spector, JE; Spector, NC; Werkhaven, JA, 2001) |
| "Mitomycin C suppository was significantly less toxic compared with intravenous delivery, and higher rectal tissue concentrations were observed from 10 to 30 minutes (P < 0." | 1.30 | Suppository administration of chemotherapeutic drugs with concomitant radiation for rectal cancer. ( Ackerman, D; Galandiuk, S; Hofmeister, A; LaRocca, R; Lewis, RK; Myers, SR; Paris, KJ; Pokorny, RM; Wrightson, WR, 1997) |
| "This metastatic model of human stomach cancer shows that locally growing and metastatic tumors may have different chemosensitivities, and provides the opportunity to test both with various treatment regimens." | 1.29 | Differential chemosensitivity of local and metastatic human gastric cancer after orthotopic transplantation of histologically intact tumor tissue in nude mice. ( Furukawa, T; Hoffman, RM; Kitajima, M; Kubota, T; Kuo, TH; Watanabe, M, 1993) |
| "Pancreatic cancer is a disease with essentially no effective treatment." | 1.29 | A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. ( Furukawa, T; Hoffman, RM; Kitajima, M; Kubota, T; Watanabe, M, 1993) |
| "All the gastric cancer lesions without liver metastases were resected 14 days after implantation of VX2 cancer cells into the stomach, and all the animals were autopsied 14 days after resection." | 1.29 | [Prophylactic effects of mitomycin C (MMC) on the liver recurrence in a rabbit gastric VX2 cancer model with high frequency of the recurrence]. ( Nakamura, T; Saitoh, Y; Tabuchi, Y; Tada, Y, 1993) |
| ") doses for dose-response and sub-acute (0." | 1.29 | Use of chick, Gallus domesticus, as an in vivo model for the study of chromosome aberration: a study with mitomycin C and probable location of a 'hot spot'. ( Bhunya, SP; Jena, GB, 1995) |
| " Taking advantage of this pharmacodynamic effect, we have previously shown that FAA in combination with hyperthermia (HT) can produce a marked improvement in antitumor response in mice." | 1.29 | Flavone acetic acid increases the cytotoxicity of mitomycin C when combined with hyperthermia. ( Baba, H; Maehara, Y; Newman, RA; Sugimachi, K; Takeuchi, H, 1996) |
| "Mitomycin C was estimated to be at least 125 times as potent as 5-FU in inhibiting corneal epithelial healing." | 1.28 | Inhibition of corneal epithelial wound healing. A comparative study of mitomycin C and 5-fluorouracil. ( Ando, H; Ido, T; Kawai, Y; Kitazawa, Y; Yamamoto, T, 1992) |
| "When mitomycin C-treated B cells were added to in vitro culture of responder B cells as a stimulator, Ig production of responder B cells was enhanced in a concentration-dependent manner." | 1.28 | B-B cell interactions in the spontaneous activation of B cells in autoimmune NZB mice. ( Eto, S; Ota, T; Saito, K; Tanaka, Y; Yamashita, U, 1991) |
| "When mitomycin C (MMC) was administered into the superior mesenteric vein 15 min after the inoculation of tumor cells, the number of metastatic foci in the liver was strongly inhibited; 81." | 1.27 | Liver metastasis of colon 26 cells implanted into the superior mesenteric vein in mice. ( Kitamura, M; Kosaki, G; Tominaga, T; Yoshida, Y, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (4.44) | 18.7374 |
| 1990's | 28 (15.56) | 18.2507 |
| 2000's | 59 (32.78) | 29.6817 |
| 2010's | 73 (40.56) | 24.3611 |
| 2020's | 12 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Trunz, BB | 1 |
| Jędrysiak, R | 1 |
| Tweats, D | 1 |
| Brun, R | 1 |
| Kaiser, M | 1 |
| Suwiński, J | 1 |
| Torreele, E | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Wang, SC | 1 |
| Yu, CY | 1 |
| Wu, YC | 1 |
| Chang, YC | 1 |
| Chen, SL | 1 |
| Sung, WW | 1 |
| Carré, C | 1 |
| Baudin, F | 1 |
| Buteau, B | 1 |
| Martine, L | 1 |
| Grégoire, S | 1 |
| Vasku, G | 1 |
| Berdeaux, O | 1 |
| Béduneau, A | 1 |
| Pellequer, Y | 1 |
| Jamoussi, J | 1 |
| Desrumeaux, C | 1 |
| Aho, S | 1 |
| Bron, AM | 1 |
| Acar, N | 1 |
| Creuzot-Garcher, C | 1 |
| Gabrielle, PH | 1 |
| Fan Gaskin, JC | 1 |
| Kong, RCK | 1 |
| Shah, MH | 1 |
| Edgley, AJ | 1 |
| Peshavariya, HM | 1 |
| Chan, EC | 1 |
| Geva, R | 1 |
| Alon, G | 1 |
| Nathanson, M | 1 |
| Bar-David, S | 1 |
| Nevo, N | 1 |
| Aizic, A | 1 |
| Peles-Avraham, S | 1 |
| Lahat, G | 1 |
| Nizri, E | 1 |
| Nemoto, E | 1 |
| Kojima, S | 2 |
| Sugiyama, T | 2 |
| Jin, D | 2 |
| Takai, S | 2 |
| Maeda, M | 1 |
| Kohmoto, R | 1 |
| Ueki, M | 2 |
| Oku, H | 2 |
| Ikeda, T | 2 |
| Xu, F | 1 |
| Shen, X | 2 |
| Sun, C | 1 |
| Xu, X | 1 |
| Wang, W | 1 |
| Zheng, J | 1 |
| Olmos-Zuñiga, JR | 1 |
| Baltazares-Lipp, M | 1 |
| Hernández-Jiménez, C | 1 |
| Jasso-Victoria, R | 1 |
| Gaxiola-Gaxiola, M | 1 |
| Silva-Martínez, M | 1 |
| Iñiguez-García, MA | 1 |
| González-González, AI | 1 |
| Vázquez-Minero, JC | 1 |
| Luna-Flores, A | 1 |
| Solis-Alanis, N | 1 |
| Baltazares-Lipp, ME | 1 |
| Pan, Y | 1 |
| Yang, X | 2 |
| Zhang, F | 1 |
| Chen, S | 2 |
| Zhou, Z | 1 |
| Yin, H | 1 |
| Ma, H | 1 |
| Shang, L | 1 |
| Yang, J | 2 |
| Li, G | 1 |
| Wang, Y | 1 |
| Jin, L | 1 |
| Shi, Q | 1 |
| Wu, Y | 3 |
| Swogger, J | 1 |
| Conner, IP | 1 |
| Happ-Smith, C | 1 |
| Kemmerer, MC | 1 |
| Julian, DR | 1 |
| Davis, R | 1 |
| Wells, A | 1 |
| Schuman, JS | 1 |
| Yates, CC | 1 |
| García-Olmo, D | 1 |
| Villarejo Campos, P | 1 |
| Barambio, J | 1 |
| Gomez-Heras, SG | 1 |
| Vega-Clemente, L | 1 |
| Olmedillas-Lopez, S | 1 |
| Guadalajara, H | 1 |
| Garcia-Arranz, M | 1 |
| Taibi, A | 1 |
| Perrin, ML | 1 |
| Albouys, J | 1 |
| Jacques, J | 1 |
| Yardin, C | 1 |
| Durand-Fontanier, S | 1 |
| Bardet, SM | 1 |
| Xie, H | 1 |
| Wang, B | 1 |
| Qin, J | 1 |
| Jiang, L | 1 |
| Yu, C | 1 |
| Geng, D | 1 |
| Yuan, T | 1 |
| Wu, T | 1 |
| Cao, X | 1 |
| Liu, J | 1 |
| Lemes, SR | 1 |
| Chaves, DA | 1 |
| Silva, NJD | 1 |
| Carneiro, CC | 1 |
| Chen-Chen, L | 1 |
| Almeida, LM | 1 |
| Gonçalves, PJ | 1 |
| Melo-Reis, PR | 1 |
| Chong, RS | 1 |
| Lee, YS | 1 |
| Chu, SWL | 1 |
| Toh, LZ | 1 |
| Wong, TTL | 1 |
| Lev, A | 1 |
| Deihimi, S | 1 |
| Shagisultanova, E | 1 |
| Xiu, J | 1 |
| Lulla, AR | 1 |
| Dicker, DT | 1 |
| El-Deiry, WS | 1 |
| Sato, N | 1 |
| Haga, J | 1 |
| Anazawa, T | 1 |
| Kenjo, A | 1 |
| Kimura, T | 1 |
| Wada, I | 1 |
| Mori, T | 2 |
| Marubashi, S | 1 |
| Gotoh, M | 2 |
| Zhang, RX | 1 |
| Zhang, T | 1 |
| Chen, K | 1 |
| Cheng, J | 1 |
| Lai, P | 1 |
| Rauth, AM | 1 |
| Pang, KS | 1 |
| Wu, XY | 1 |
| Anumanthan, G | 1 |
| Sharma, A | 2 |
| Waggoner, M | 1 |
| Hamm, CW | 1 |
| Gupta, S | 1 |
| Hesemann, NP | 1 |
| Mohan, RR | 2 |
| Bhandari, P | 1 |
| Novikova, G | 1 |
| Goergen, CJ | 1 |
| Irudayaraj, J | 1 |
| Park, JS | 1 |
| Jeong, S | 1 |
| Lee, DH | 1 |
| Rangel, HMDA | 1 |
| Rolim, HT | 1 |
| Vidigal, P | 1 |
| Araújo, ID | 1 |
| Cronemberger, S | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Ghobakhloo, N | 1 |
| Sutton, R | 1 |
| Ambrosio, L | 1 |
| Meng, X | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
| Yoon, SY | 1 |
| Kim, ES | 1 |
| Han, GS | 1 |
| Suh, LH | 1 |
| Jung, HS | 1 |
| Tchah, H | 1 |
| Kim, JY | 1 |
| Flatmark, K | 1 |
| Guldvik, IJ | 1 |
| Svensson, H | 1 |
| Fleten, KG | 1 |
| Flørenes, VA | 1 |
| Reed, W | 1 |
| Giercksky, KE | 1 |
| Fodstad, Ø | 1 |
| Andersson, Y | 1 |
| Francescutti, V | 1 |
| Rivera, L | 1 |
| Seshadri, M | 1 |
| Kim, M | 1 |
| Haslinger, M | 1 |
| Camoriano, M | 1 |
| Attwood, K | 1 |
| Kane, JM | 1 |
| Skitzki, JJ | 1 |
| Butler, MR | 1 |
| Prospero Ponce, CM | 1 |
| Weinstock, YE | 1 |
| Orengo-Nania, S | 1 |
| Chevez-Barrios, P | 1 |
| Frankfort, BJ | 1 |
| Schomisch, SJ | 1 |
| Cipriano, C | 1 |
| Chak, A | 1 |
| Lash, RH | 1 |
| Ponsky, JL | 1 |
| Marks, JM | 1 |
| Jankun, J | 1 |
| Keck, RW | 3 |
| Selman, SH | 3 |
| Woo, JE | 1 |
| Park, WC | 1 |
| Yoo, YH | 1 |
| Kim, SW | 1 |
| Ma, J | 1 |
| Li, X | 1 |
| Zhang, W | 1 |
| Huang, L | 2 |
| Chen, M | 1 |
| Xi, L | 1 |
| Zhang, Z | 1 |
| Duan, L | 1 |
| Quan, D | 1 |
| Ge, J | 2 |
| Bartek, IL | 1 |
| Woolhiser, LK | 1 |
| Baughn, AD | 1 |
| Basaraba, RJ | 1 |
| Jacobs, WR | 1 |
| Lenaerts, AJ | 1 |
| Voskuil, MI | 1 |
| Uyeturk, U | 1 |
| Gucuk, A | 1 |
| Firat, T | 1 |
| Kemahli, E | 1 |
| Kukner, A | 1 |
| Ozyalvacli, ME | 1 |
| Liang, Y | 1 |
| Feng, Q | 1 |
| Hong, J | 1 |
| Feng, F | 1 |
| Sang, Y | 1 |
| Hu, W | 1 |
| Xu, M | 1 |
| Peng, R | 1 |
| Kang, T | 1 |
| Bei, J | 1 |
| Zeng, Y | 1 |
| Tabata, Y | 1 |
| Kwan, BW | 1 |
| Chowdhury, N | 1 |
| Wood, TK | 2 |
| Chang, IY | 1 |
| Kim, JN | 1 |
| Kim, SO | 1 |
| Han, M | 1 |
| Huh, JS | 1 |
| Maeng, YH | 1 |
| Yoon, SP | 1 |
| Eren, K | 1 |
| Turgut, B | 1 |
| Akin, MM | 1 |
| Demir, T | 1 |
| Van Bergen, T | 2 |
| Vandewalle, E | 1 |
| Moons, L | 2 |
| Stalmans, I | 2 |
| Wang, AY | 2 |
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| Liew, LJ | 2 |
| Wang, JT | 2 |
| von Unge, M | 2 |
| Atlas, MD | 2 |
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| Humbert, M | 2 |
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| Zhang, H | 1 |
| Wang, J | 5 |
| Pal-Ghosh, S | 1 |
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| Sherwood, MB | 5 |
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| Liang, ZK | 1 |
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| Hu, ZM | 1 |
| Chen, Z | 1 |
| Huang, X | 1 |
| Shi, XH | 1 |
| Tan, WL | 1 |
| Gao, JM | 1 |
| Hirooka, K | 1 |
| Takagishi, M | 1 |
| Baba, T | 1 |
| Shiraga, F | 1 |
| Sen, S | 3 |
| Meteoglu, I | 1 |
| Ogurlu, M | 1 |
| Derincegoz, OO | 1 |
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| Barutca, S | 1 |
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| Van Cleynenbreugel, B | 1 |
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| Lerut, E | 1 |
| Agostinis, P | 1 |
| de Witte, PA | 2 |
| Kocaoglu, B | 1 |
| Akgun, U | 1 |
| Nalbantoglu, U | 1 |
| Poyanlı, O | 1 |
| Karahan, M | 1 |
| Yan, L | 2 |
| Sun, Y | 2 |
| Dai, S | 2 |
| Feng, X | 2 |
| Jiang, B | 2 |
| Wang, Q | 3 |
| Yu, T | 2 |
| Shi, X | 1 |
| Ye, H | 1 |
| Qian, Y | 1 |
| Lin, M | 1 |
| Duan, Y | 1 |
| Sun, X | 1 |
| Zhuo, Y | 1 |
| Zhong, H | 1 |
| Sun, G | 1 |
| Lin, X | 1 |
| Wu, K | 1 |
| Yu, M | 1 |
| Senturk, E | 1 |
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| Hou, JC | 1 |
| Landas, S | 1 |
| Wang, CY | 1 |
| Shapiro, O | 1 |
| Kavuzlu, A | 1 |
| Arslan, N | 1 |
| Tastan, E | 1 |
| Islam, A | 1 |
| Ustun, H | 2 |
| Aydogan, F | 1 |
| Zhu, GH | 1 |
| Ng, AH | 1 |
| Venkatraman, SS | 1 |
| Boey, FY | 1 |
| Wee, AL | 1 |
| Trasti, SL | 1 |
| Yee Lim, LH | 1 |
| Li, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnostic Value and Biological Significant of cd71 in Lymphoid Dis Order[NCT03720977] | 139 participants (Anticipated) | Observational | 2019-12-01 | Not yet recruiting | |||
| Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489] | Phase 4 | 70 participants | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mitomycin and Disease Models, Animal
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topical use of MMC in the upper aerodigestive tract: a review on the side effects.
Topics: Administration, Topical; Adolescent; Adult; Airway Obstruction; Animals; Child; Child, Preschool; Ci | 2010 |
[Drug-induced glomerular nephropathies].
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Daunorubicin; Disease Models, Animal; Doxorubici | 1983 |
1 trial available for mitomycin and Disease Models, Animal
177 other studies available for mitomycin and Disease Models, Animal
| Article | Year |
|---|---|
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Dr | 2011 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Chidamide and mitomycin C exert synergistic cytotoxic effects against bladder cancer cells in vitro and suppress tumor growth in a rat bladder cancer model.
Topics: Administration, Intravesical; Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; BCG Vaccine | 2022 |
Effects of topical docosahexaenoic acid on postoperative fibrosis in an animal model of glaucoma filtration surgery.
Topics: Animals; Disease Models, Animal; Docosahexaenoic Acids; Fibrosis; Filtering Surgery; Glaucoma; Intra | 2023 |
Inhibitory Effects of 3',4'-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts.
Topics: Animals; Collagen; Disease Models, Animal; Fibroblasts; Filtering Surgery; Flavonols; Glaucoma; Huma | 2022 |
PD-1 Blockade Combined with Heated Intraperitoneal Chemotherapy Improves Outcome in Experimental Peritoneal Metastases from Colonic Origin in a Murine Model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combined Modality The | 2023 |
Effects of Regorafenib, a Multi-Kinase Inhibitor, on Conjunctival Scarring in a Canine Filtration Surgery Model in Comparison with Mitomycin-C.
Topics: Animals; Antimetabolites; Conjunctiva; Disease Models, Animal; Dogs; Filtering Surgery; Glaucoma; In | 2019 |
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Survival; Collagen Type I; Disease Models, Animal; | 2020 |
Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection.
Topics: Anastomosis, Surgical; Animals; Cicatrix; Collagen; Decorin; Disease Models, Animal; Dogs; Extracell | 2020 |
A heterozygous hypomorphic mutation of Fanca causes impaired follicle development and subfertility in female mice.
Topics: Alkylating Agents; Animals; Base Sequence; Disease Models, Animal; DNA Repair; Embryo, Mammalian; Fa | 2021 |
Novel combination therapy reduces subconjunctival fibrosis after glaucoma filtration surgery in the rabbit model.
Topics: Animals; Conjunctiva; Disease Models, Animal; Fibrosis; Filtering Surgery; Glaucoma; Intraocular Pre | 2021 |
Intraperitoneal collagenase as a novel therapeutic approach in an experimental model of colorectal peritoneal carcinomatosis.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma; Collagenases; Colorectal Neoplasms; Disease Models, | 2021 |
10 ns PEFs induce a histological response linked to cell death and cytotoxic T-lymphocytes in an immunocompetent mouse model of peritoneal metastasis.
Topics: Animals; Antibiotics, Antineoplastic; Cell Death; Colorectal Neoplasms; Combined Modality Therapy; D | 2021 |
MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy.
Topics: Animals; Cicatrix; Delayed-Action Preparations; Disease Models, Animal; Epidural Space; Fibrosis; La | 2017 |
Antigenotoxicity protection of Carapa guianensis oil against mitomycin C and cyclophosphamide in mouse bone marrow.
Topics: Animals; Antimutagenic Agents; Bone Marrow Cells; Cyclophosphamide; Disease Models, Animal; Male; Me | 2017 |
Inhibition of Monocyte Chemoattractant Protein 1 Prevents Conjunctival Fibrosis in an Experimental Model of Glaucoma Filtration Surgery.
Topics: Animals; Antifibrinolytic Agents; Cell Survival; Chemokine CCL2; Collagen; Conjunctiva; Disease Mode | 2017 |
Preclinical rationale for combination of crizotinib with mitomycin C for the treatment of advanced colorectal cancer.
Topics: Alleles; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms | 2017 |
Ex vivo Pretreatment of Islets with Mitomycin C: Reduction in Immunogenic Potential of Islets by Suppressing Secretion of Multiple Chemotactic Factors.
Topics: Animals; Chemotactic Factors; Disease Models, Animal; Humans; Islets of Langerhans; Male; Mice; Mice | 2017 |
Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Anima | 2017 |
Efficacy and Safety Comparison Between Suberoylanilide Hydroxamic Acid and Mitomycin C in Reducing the Risk of Corneal Haze After PRK Treatment In Vivo.
Topics: Alkylating Agents; Animals; Apoptosis; Cornea; Corneal Opacity; Disease Models, Animal; Fluorescent | 2017 |
Ultrasound beam steering of oxygen nanobubbles for enhanced bladder cancer therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cellulose; Disease Models, Animal; Drug Deli | 2018 |
Effects of mitomycin-eluting metal stents on benign biliary stricture in a swine model: A feasibility study.
Topics: Animals; Cholestasis; Disease Models, Animal; Drug-Eluting Stents; Feasibility Studies; Mitomycin; N | 2018 |
Healing modulation in glaucoma surgery after application of subconjunctival triamcinolone acetate alone or combined with mitomycin C: an experimetal study.
Topics: Animals; Anti-Inflammatory Agents; Blister; Conjunctiva; Disease Models, Animal; Drug Therapy, Combi | 2018 |
Lower Abundance and Impaired Function of CD71+ Erythroid Cells in Inflammatory Bowel Disease Patients During Pregnancy.
Topics: Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Models, An | 2019 |
Safety and efficacy of tacrolimus-coated silicone plates as an alternative to mitomycin C in a rabbit model of conjunctival fibrosis.
Topics: Animals; Conjunctiva; Conjunctival Diseases; Cornea; Disease Models, Animal; Fibroblasts; Fibrosis; | 2019 |
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies.
Topics: ADP Ribose Transferases; Animals; Antigens, Neoplasm; Bacterial Toxins; Cell Adhesion Molecules; Dis | 2013 |
The benefit of intraperitoneal chemotherapy for the treatment of colorectal carcinomatosis.
Topics: Animals; Carcinoma; Cell Line, Tumor; Cell Survival; Chemotherapy, Cancer, Regional Perfusion; Color | 2013 |
Topical silver nanoparticles result in improved bleb function by increasing filtration and reducing fibrosis in a rabbit model of filtration surgery.
Topics: Administration, Topical; Analysis of Variance; Animals; Anti-Infective Agents, Local; Antibiotics, A | 2013 |
Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures.
Topics: Angiogenesis Inhibitors; Animals; Cicatrix; Disease Models, Animal; Dissection; Drug Therapy, Combin | 2014 |
Epigallocatechin-3-gallate prevents tumor cell implantation/growth in an experimental rat bladder tumor model.
Topics: Animals; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; | 2014 |
The efficacy of co-treatment with suberoylanilide hydroxamic acid and mitomycin C on corneal scarring after therapeutic keratectomy: an animal study.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Cicatrix; Corneal Diseases; Cytokin | 2014 |
CSM enhances the filtration bleb survival in rabbit model of experimental glaucoma surgery.
Topics: Alkylating Agents; Animals; Chitosan; Conjunctiva; Disease Models, Animal; Drug Carriers; Fibrosis; | 2014 |
Mycobacterium tuberculosis Lsr2 is a global transcriptional regulator required for adaptation to changing oxygen levels and virulence.
Topics: Adaptation, Physiological; Anaerobiosis; Animals; Disease Models, Animal; DNA-Binding Proteins; Gene | 2014 |
Effect of mitomycin, bevacizumab, and 5-Fluorouracil to inhibit urethral fibrosis in a rabbit model.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Bevacizumab; Collagen; Disease | 2014 |
Tumor growth and metastasis can be inhibited by maintaining genomic stability in cancer cells.
Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Genomic Instability; Humans; Mice; Mitom | 2015 |
Effects of Gelatin Hydrogel Loading Mitomycin C on Conjunctival Scarring in a Canine Filtration Surgery Model.
Topics: Administration, Topical; Animals; Cicatrix; Conjunctiva; Conjunctival Diseases; Disease Models, Anim | 2015 |
Combatting bacterial infections by killing persister cells with mitomycin C.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Ciprofloxacin; Cross-L | 2015 |
Morphological effects of mitomycin C on urothelial responses to experimentally-induced urethral stricture in rats.
Topics: Animals; Cell Proliferation; Disease Models, Animal; DNA Damage; Male; Mitomycin; Nucleic Acid Synth | 2015 |
The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model.
Topics: Alkylating Agents; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Fibroblast Growth Facto | 2016 |
Complementary effects of bevacizumab and MMC in the improvement of surgical outcome after glaucoma filtration surgery.
Topics: Alkylating Agents; Angiogenesis Inhibitors; Animals; Bevacizumab; Chemotherapy, Adjuvant; Disease Mo | 2015 |
Searching for a rat model of chronic tympanic membrane perforation: Healing delayed by mitomycin C/dexamethasone but not paper implantation or iterative myringotomy.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease Models | 2015 |
Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models.
Topics: Adult; Animals; Antibiotics, Antineoplastic; Anus Neoplasms; Disease Models, Animal; Female; Humans; | 2015 |
Evaluation of Su Fu'ning Lotion's Inhibitory Effects on Bladder Cancer Cells In Vitro and In Vivo by Intravesical Instillation.
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; | 2016 |
Topical Mitomycin-C enhances subbasal nerve regeneration and reduces erosion frequency in the debridement wounded mouse cornea.
Topics: Analysis of Variance; Animals; Axons; Cell Proliferation; Cornea; Corneal Injuries; Debridement; Dis | 2016 |
Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Bevacizumab; Bl | 2015 |
Quantifying the Ototoxicity of Mitomycin: Before versus after Myringotomy.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Chinchilla; Disease Models, Animal; D | 2015 |
Fancb deficiency impairs hematopoietic stem cell function.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cell P | 2015 |
Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease | 2016 |
Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Daunorubicin; Disease Models, Animal; Female; Fibros | 2016 |
Letter by Belge et al Regarding Article, "Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models".
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Female; Humans; Male; Mitomycin; Pulmo | 2016 |
Response to Letter Regarding Article, "Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Model".
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Female; Humans; Male; Mitomycin; Pulmo | 2016 |
Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis.
Topics: Animals; Apoptosis; Autoantigens; Cell Movement; Disease Models, Animal; Encephalomyelitis, Autoimmu | 2016 |
Leukemic survival factor SALL4 contributes to defective DNA damage repair.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Chromosomal Instability; Cluster Analysis; | 2016 |
Prevention of anterior glottis web with hyaluronic acid derivatives in rabbit model.
Topics: Animals; Collagen; Disease Models, Animal; Glottis; Hyaluronic Acid; Laryngeal Diseases; Mitomycin; | 2016 |
Quantitative Analysis of Collagen Produced by Rabbit Keratocytes using Second Harmonic Generation Microscopy.
Topics: Animals; Biomarkers; Cell Count; Cells, Cultured; Collagen; Corneal Injuries; Corneal Keratocytes; C | 2017 |
The Combination of PlGF Inhibition and MMC as a Novel Anti-Scarring Strategy for Glaucoma Filtration Surgery.
Topics: Animals; Anterior Chamber; Blood Proteins; Cicatrix; Disease Models, Animal; Filtering Surgery; Glau | 2016 |
α5β1-Integrin inhibitor (CLT-28643) effective in rabbit trabeculectomy model.
Topics: Administration, Topical; Alkylating Agents; Aminoquinolines; Animals; Collagen; Conjunctiva; Disease | 2017 |
Repurposing the anticancer drug mitomycin C for the treatment of persistent Acinetobacter baumannii infections.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Antibiotics, Anti | 2017 |
The effects of hyperthermic intraperitoneal chemoperfusion on colonic anastomosis: an experimental study in a rat model.
Topics: Anastomosis, Surgical; Animals; Chemotherapy, Adjuvant; Cisplatin; Colorectal Neoplasms; Combined Mo | 2017 |
Effect of mitomycin in the surgical treatment of tracheal stenosis.
Topics: Airway Obstruction; Anastomosis, Surgical; Animals; Antimitotic Agents; Biopsy; Bronchoscopy; Diseas | 2008 |
DNA cross-linking, double-strand breaks, and apoptosis in corneal endothelial cells after a single exposure to mitomycin C.
Topics: Animals; Annexin A5; Apoptosis; Cell Count; Cells, Cultured; Comet Assay; Disease Models, Animal; DN | 2008 |
The effects of adjuvant experimental radioimmunotherapy and hyperthermic intraperitoneal chemotherapy on intestinal and abdominal healing after cytoreductive surgery for peritoneal carcinomatosis in the rat.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, R | 2008 |
[Therapeutic effects of chitosan/polyethylene glycols-succinate/mitomycin C film drug delivery system on epidural scarring tissues after laminectomy of SD rats].
Topics: Animals; Biocompatible Materials; Chitosan; Cicatrix; Disease Models, Animal; Drug Delivery Systems; | 2008 |
Study of wound healing in rats treated with topical and injected mitomycin C.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Cell Proliferation; Disease Models, A | 2008 |
Mitomycin C decreases the rate of stricture formation in caustic esophageal burns in rats.
Topics: Administration, Topical; Alkalies; Animals; Antibiotics, Antineoplastic; Burns, Chemical; Disease Mo | 2009 |
Prevention and treatment of transitional cell carcinomatosis with intraperitoneal chemotherapy in a rat model.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Disease Models, Animal; Mitomyci | 2009 |
A thin honeycomb-patterned film as an adhesion barrier in an animal model of glaucoma filtration surgery.
Topics: Absorbable Implants; Animals; Blister; Conjunctival Diseases; Disease Models, Animal; Filtering Surg | 2009 |
[A simple and efficient method for establishing a mouse model of orthotopic MB49 bladder cancer].
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Mice; Mi | 2009 |
Correlation between optical coherence tomography scan and histological specimen of a filtering bleb.
Topics: Animals; Aqueous Humor; Blister; Conjunctiva; Disease Models, Animal; Female; Filtering Surgery; His | 2010 |
Topical heparin: a promising agent for the prevention of tracheal stenosis in airway surgery.
Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Fibrosis; Granulation Tissue; Heparin; Mitomyc | 2009 |
Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasm | 2010 |
An improved orthotopic rat bladder tumor model using Dil-loaded fluorescent AY-27 cells.
Topics: Animals; Antibiotics, Antineoplastic; Carbocyanines; Cell Line, Tumor; Disease Models, Animal; Femal | 2010 |
Adhesion reduction after knee surgery in a rat model by mitomycin C.
Topics: Animals; Cell Proliferation; Cicatrix; Disease Models, Animal; Female; Fibrosis; Foreign-Body Reacti | 2011 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fib | 2010 |
Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery.
Topics: Animals; Biological Assay; Cations; Cell Count; Cell Proliferation; Cell Survival; Disease Models, A | 2010 |
Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery.
Topics: Actins; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Ce | 2011 |
Comparison of mitomycin-c and heparin affects in experimental corrosive esophagitis on rats.
Topics: Alkylating Agents; Animals; Burns, Chemical; Caustics; Disease Models, Animal; Esophagitis; Female; | 2011 |
Instillation of mitomycin C after transurethral resection of bladder cancer impairs wound healing: an animal model.
Topics: Administration, Intravesical; Animals; Disease Models, Animal; Female; Mitomycin; Rats; Rats, Spragu | 2011 |
The effects of repetitious topical use of mitomycin C on antrostomy patency in maxillary antrostomy created rabbit model.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Dose-Response | 2011 |
A comparative study of the inhibiting effects of mitomycin C and polyphenolic catechins on tumor cell implantation/growth in a rat bladder tumor model.
Topics: Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Cell Prol | 2011 |
A novel bioabsorbable drug-eluting tracheal stent.
Topics: Absorbable Implants; Animals; Bronchoscopy; Disease Models, Animal; Drug-Eluting Stents; Female; Mal | 2011 |
2A peptide-based, lentivirus-mediated anti-death receptor 5 chimeric antibody expression prevents tumor growth in nude mice.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Cell Death; Disease Models, Animal; Drug Synergi | 2012 |
Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model.
Topics: Alkylating Agents; Animals; Antibodies, Monoclonal, Humanized; Cicatrix; Conjunctiva; Disease Models | 2013 |
Microscopic comparison of topical use of Mitomycin C and Fluorouracil on cold knife myringotomy.
Topics: Administration, Topical; Animals; Disease Models, Animal; Female; Fluorouracil; Immunohistochemistry | 2012 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2012 |
Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery.
Topics: Administration, Topical; Alkylating Agents; Animals; Cicatrix; Conjunctival Diseases; Disease Models | 2012 |
Prevention of ocular scarring post glaucoma filtration surgery using the inflammatory cell and platelet binding modulator saratin in a rabbit model.
Topics: Administration, Topical; Animals; Blood Platelets; Cicatrix; Disease Models, Animal; Eye; Fibrosis; | 2012 |
Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.
Topics: Animals; Bone Marrow Cells; Cyclophosphamide; Cytogenetics; Disease Models, Animal; Fanconi Anemia; | 2012 |
Suppression of avascular bleb formation by a thin biodegradable film in a rabbit filtration surgery with mitomycin C.
Topics: Absorbable Implants; Alkylating Agents; Animals; Biocompatible Materials; Conjunctival Diseases; Dis | 2012 |
The effect of mitomycin-C in reducing pericardial adhesion after cardiac surgery in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Cardiac Surgical Procedures; Disease Models, Animal; Mitomycin | 2013 |
New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Chemotherapy, Cancer, Regional | 2012 |
The use of mitomycin C in caustic esophagitis in rats.
Topics: Animals; Burns, Chemical; Caustics; Dilatation; Disease Models, Animal; Esophageal Stenosis; Male; M | 2013 |
Comet-FISH studies for evaluation of genetic damage of citalopram in somatic cells of the mouse.
Topics: Administration, Oral; Animals; Bone Marrow; Centromere; Citalopram; Colchicine; Comet Assay; Disease | 2013 |
Application of poly-lactide-co-glycolide-microspheres in the transarterial chemoembolization in an animal model of hepatocellular carcinoma.
Topics: Animals; Antibiotics, Antineoplastic; Arteries; Carcinoma, Hepatocellular; Chemoembolization, Therap | 2003 |
A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Antineoplastic Combined Chemotherapy Protocols; Ataxia; Behav | 2003 |
Allogeneic cell stimulation enhances cytomegalovirus replication in the early period of primary infection in an experimental rat model.
Topics: Alkylating Agents; Animals; Cytomegalovirus; Cytomegalovirus Infections; Disease Models, Animal; Gra | 2003 |
Development of a lethal Shiga toxin-producing Escherichia coli-infection mouse model using multiple mitomycin C treatment.
Topics: Alkylating Agents; Animals; Blood Urea Nitrogen; Bone Marrow; Creatinine; Disease Models, Animal; Es | 2003 |
Permanent acceptance of mitomycin C-treated islet allograft.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Graft Survival; Imm | 2003 |
Potentiation of photodynamic therapy with hypericin by mitomycin C in the radiation-induced fibrosarcoma-1 mouse tumor model.
Topics: Animals; Anthracenes; Disease Models, Animal; Drug Synergism; Female; Fibrosarcoma; Mice; Mitomycin; | 2003 |
Inhibitory effects of aqueous crude extract of Saffron (Crocus sativus L.) on chemical-induced genotoxicity in mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Chromosome Disorders; Cisplatin; Complex Mixtures | 2003 |
Application of molecular diagnosis for detection of peritoneal micrometastasis and evaluation of preoperative chemotherapy in advanced gastric carcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; C | 2004 |
[An improved animal model for chronic perforation of the tympanic membrane].
Topics: Administration, Topical; Animals; Chronic Disease; Disease Models, Animal; Male; Microsurgery; Mitom | 2004 |
Erythropoietin modulates the anticancer activity of chemotherapeutic drugs in a murine lung cancer model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Lewis Lung; Cisplatin; C | 2004 |
Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Disease Models, Animal; Dose-Response Relationship, | 2004 |
Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat.
Topics: Animals; Catheterization; Colitis; Colon; Dextran Sulfate; Dimerization; Disease Models, Animal; Fem | 2005 |
Mitomycin C prevents strictures in caustic esophageal burns in rats.
Topics: Alkalies; Animals; Antibiotics, Antineoplastic; Body Weight; Burns, Chemical; Disease Models, Animal | 2005 |
Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Conjunctiva; Disease Models, Animal; Enzyme Inhibito | 2005 |
Liver metastases in rats: chemoembolization combined with interstitial laser ablation for treatment.
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Chemoembolization, Therapeutic; Colorect | 2005 |
Mitomycin C effect on fibrous adhesions of rabbit temporomandibular joint.
Topics: Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administrati | 2005 |
Effect of topical mitomycin C on the healing of surgical and laser wounds: a hint on clinical application.
Topics: Administration, Topical; Animals; Cell Proliferation; Cicatrix; Dermatologic Surgical Procedures; Di | 2005 |
Effects of fluoxetine on cellular immune response in stressed mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Cell | 2006 |
Can mitomycin C really prevent airway stenosis?
Topics: Airway Obstruction; Animals; Disease Models, Animal; Female; Follow-Up Studies; Glottis; Mitomycin; | 2006 |
Halofuginone prevents subglottic stenosis in a canine model.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Dogs; Fibroblasts; Follow-Up Studies; Humans; In V | 2006 |
Effect of topical mitomycin C for antrostomy in rabbit with sinusitis.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Cicatrix; Disease Models, Animal; Mal | 2006 |
Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits.
Topics: Animals; Apoptosis; Cell Count; Cell Proliferation; Cornea; Corneal Opacity; Disease Models, Animal; | 2006 |
The effects of intradermal and topical mitomycin C on wound healing.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Fibroblasts; Follow-Up Studies; Immunohistochem | 2006 |
Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1.
Topics: Animals; Bone Marrow Cells; BRCA2 Protein; Cell Proliferation; Chromosome Aberrations; Disease Model | 2006 |
Injection of cultured autologous fibroblasts into the subconjunctival space of rabbits treated with mitomycin C.
Topics: Animals; Antibiotics, Antineoplastic; Atrophy; Cells, Cultured; Conjunctiva; Conjunctival Diseases; | 2006 |
CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adoptive Transfer; Animals; Antineoplastic Combined Ch | 2007 |
Benefits and risks of mitomycin use in the traumatized tracheal mucosa.
Topics: Airway Obstruction; Animals; Antibiotics, Antineoplastic; Cause of Death; Cicatrix; Disease Models, | 2007 |
Refining indications for the use of mitomycin C using a randomized controlled trial with an animal model.
Topics: Animals; Disease Models, Animal; Ferrets; Laryngostenosis; Mitomycin; Randomized Controlled Trials a | 2007 |
[Establishment and application of an orthotopic murine bladder cancer model].
Topics: Animals; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Down-Regulation; Female; Gadolini | 2007 |
Trans-arterial gene therapy for hepatocellular carcinoma in a rabbit model.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Combined Modality Therapy; Disease | 2007 |
A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis).
Topics: Alkylating Agents; Animals; Antimetabolites; Blister; Conjunctiva; Connective Tissue; Connective Tis | 2006 |
Re: Hamid Mazdak, Iraj Meshki and Fatemeh Ghassami. Effect of mitomycin C on anterior urethral stricture recurrence after internal urethrotomy. Eur Urol 2007;51:1089-92.
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Humans; Mitomycin; Rats; Secondary Pre | 2007 |
[The effect of topical mitomycin-C application before or after incisional myringotomy on patency times of guinea pig tympanic membrane perforations].
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Guinea Pigs; | 2007 |
Antiadhesive effects of mitomycin C and streptopeptidase A in rats with intraperitoneal adhesions.
Topics: Animals; Anti-Inflammatory Agents; Clostridium histolyticum; Disease Models, Animal; Hydroxyproline; | 2007 |
A comparison between radioimmunotherapy and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal carcinomatosis of colonic origin in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Body Weight; Colonic Neoplasms; Combin | 2007 |
The effect of topical mitomycin C on full-thickness burns.
Topics: Administration, Topical; Animals; Burns, Chemical; Chlorhexidine; Disease Models, Animal; Disinfecta | 2007 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Chemotherapeutic study on Yoshida sarcoma ascites cells implanted into the glandular stomach of rats. Monotherapy with 5-fluorouracil, methyl-CCNU, mitomycin C, adriamycin, and cytosine arabinoside, and combination therapy with respective two-drug combina
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Disease Models, Animal; Dox | 1983 |
Immunoregulation in experimental Schistosomiasis. III. Role of macrophages in soluble egg antigen-induced chronic spleen cell augmentation of baseline lymphocyte reactivity.
Topics: Animals; Antigens; Cells, Cultured; Disease Models, Animal; DNA Replication; Female; Lymphocyte Acti | 1984 |
16-16 dimethyl prostaglandin E2 reduces 5-fluorouracil-induced and mitomycin C-induced gastric mucosal injury in the dog.
Topics: Animals; Disease Models, Animal; Dogs; Female; Fluorouracil; Gastric Acid; Gastric Mucosa; Infusions | 1984 |
Single and sequential combination intravesical chemotherapy of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Doxorubicin; Drug Therapy, Combin | 1982 |
Chemotherapy of pancreatic adenocarcinoma: initial report on two transplantable models in the Syrian hamster.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Cyclophosphamide; Disease Models, Animal | 1982 |
Use of chick, Gallus domesticus, as an in vivo model for the study of chromosome aberration: a study with mitomycin C and probable location of a 'hot spot'.
Topics: Analysis of Variance; Animals; Bone Marrow; Bone Marrow Cells; Chickens; Chromosome Aberrations; Chr | 1995 |
[Prophylactic effects of mitomycin C (MMC) on the liver recurrence in a rabbit gastric VX2 cancer model with high frequency of the recurrence].
Topics: Animals; Disease Models, Animal; Female; Injections, Intravenous; Liver Neoplasms; Mitomycin; Neopla | 1993 |
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice.
Topics: Animals; Disease Models, Animal; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neopl | 1993 |
Combined therapy of mitomycin C and Chinese medical herbs on experimental liver cancer.
Topics: Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combinatio | 1993 |
Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C.
Topics: Animals; Biopsy; Conjunctiva; Disease Models, Animal; Drug Evaluation, Preclinical; Fibroblasts; Flu | 1993 |
Differential chemosensitivity of local and metastatic human gastric cancer after orthotopic transplantation of histologically intact tumor tissue in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Combined Modali | 1993 |
Flavone acetic acid increases the cytotoxicity of mitomycin C when combined with hyperthermia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; Cell Survival; Combined | 1996 |
A novel MMC-loaded pHEMA drainage device for the treatment of glaucoma: in vitro and in vivo studies.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Conjunctiva; Cornea; Delayed-Action P | 1996 |
Assessment of the flexed-tail mouse as a possible model for Fanconi anemia: analysis of mitomycin C-induced micronuclei.
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Fanc | 1996 |
Retinal pigment epithelial debridement as a model for the pathogenesis and treatment of macular degeneration.
Topics: Animals; Atrophy; Bruch Membrane; Capillaries; Cell Division; Choroid; Debridement; Disease Models, | 1996 |
Effects of pegylated recombinant human megakaryocyte growth and development factor on thrombocytopenia induced by a new myelosuppressive chemotherapy regimen in mice.
Topics: Animals; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Humans; Male; Mice; Mice, In | 1996 |
Effects of mitomycin C on the expression of proliferating cell nuclear antigen after filtering surgery in rabbits.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Cell Division; Chemotherapy, Adjuvant; Cornea; Dis | 1997 |
Is mitomycin effective in preventing muscle migration after hang-back recession in a rabbit model?
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Cell Movement; Connective Tissue; Disease Model | 1997 |
Suppository administration of chemotherapeutic drugs with concomitant radiation for rectal cancer.
Topics: Adenocarcinoma; Administration, Rectal; Animals; Antibiotics, Antineoplastic; Chromatography, High P | 1997 |
Ocular concentrations of mitomycin C using different delivery devices.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; | 1998 |
[Therapeutic effect of matrix metalloproteinase inhibitor (R-94138) for peritoneal metastasis of stomach neoplasm models].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Models, Animal; Injectio | 1997 |
Antiproliferative effect of mitomycin C on experimental proliferative vitreoretinopathy in rabbits.
Topics: Animals; Cell Division; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; F | 1997 |
Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage.
Topics: Animals; Bone Marrow; Cell Cycle Proteins; Cross-Linking Reagents; Disease Models, Animal; DNA Damag | 1998 |
Assessment of mitomycin C sensitivity in Fanconi anemia complementation group C gene (Fac) knock-out mouse cells.
Topics: Animals; Cell Cycle Proteins; Cell Line; Disease Models, Animal; DNA-Binding Proteins; Drug Resistan | 1998 |
Development and characterization of immortalized fibroblastoid cell lines from an FA(C) mouse model.
Topics: Animals; Cell Cycle Proteins; Cell Line, Transformed; Cell Transformation, Viral; Chromosome Aberrat | 1998 |
Synthesis and effects of novel thiazole derivatives against thrombocytopenia.
Topics: Animals; Autoantibodies; Blood Platelets; Dapsone; Disease Models, Animal; Dose-Response Relationshi | 1998 |
Inhibition of subglottic stenosis with mitomycin-C in the canine model.
Topics: Administration, Topical; Airway Obstruction; Animals; Dilatation; Disease Models, Animal; Dogs; Lary | 1999 |
Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C.
Topics: Animals; Basement Membrane; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Extracel | 1996 |
Microwave thermochemotherapy in the treatment of the bladder carcinoma--electromagnetic and dielectric studies--clinical protocol.
Topics: Animals; Antibiotics, Antineoplastic; Combined Modality Therapy; Disease Models, Animal; Dogs; Elect | 2000 |
The effects of mitomycin-C and stenting on airway wound healing after laryngotracheal reconstruction in a pig model.
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Evaluation Studies as Topic; Granulati | 2000 |
Effects of mitomycin C on the oxygenation and radiosensitivity of murine and human tumours in mice.
Topics: Animals; Apoptosis; Cervix Uteri; Colon; Colonic Neoplasms; Disease Models, Animal; Female; Humans; | 2000 |
Effects of intraperitoneal mitomycin C adsorbed on activated carbon on adhesion formation and mesothelial cells in vitro.
Topics: Animals; Charcoal; Disease Models, Animal; Epithelial Cells; Fibrinolysis; Humans; In Vitro Techniqu | 2000 |
Topical use of mitomycin C in laser myringotomy: an experimental study in rats.
Topics: Administration, Topical; Animals; Combined Modality Therapy; Disease Models, Animal; Laser Therapy; | 2000 |
Establishment of an isogenic human colon tumor model for NQO1 gene expression: application to investigate the role of DT-diaphorase in bioreductive drug activation in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Disease Models, Animal; Gene Expression; HT | 2000 |
Creating a stable tympanic membrane perforation using mitomycin C.
Topics: Alkylating Agents; Animals; Chronic Disease; Disease Models, Animal; Male; Middle Ear Ventilation; M | 2001 |
Validation of an orthotopic model of human lung cancer with regional and systemic metastases.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Carcinoma, Large Cell; Cisplatin; Disease Mode | 2001 |
Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo(1).
Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; FMN Reductase; Genotype; Humans; Mice; | 2001 |
Prevention of anterior glottic restenosis in a canine model with topical mitomycin-C.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Dogs; Glottis | 2001 |
Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.
Topics: Alleles; Animals; Chromosome Breakage; Disease Models, Animal; DNA-Binding Proteins; Fanconi Anemia; | 2001 |
[Study on the reversion of drug resistance in human cervical cancer cell lines].
Topics: Animals; Antibiotics, Antineoplastic; Cyclosporins; Disease Models, Animal; Drug Resistance, Neoplas | 2001 |
Inhibition of corneal epithelial wound healing. A comparative study of mitomycin C and 5-fluorouracil.
Topics: Animals; Cell Division; Cornea; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelium | 1992 |
[Experimental chemotherapy of peritoneal carcinomatosis of colonic origin in rats].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Disease Models, Anim | 1992 |
Effect of topical mitomycin C on glaucoma filtration surgery in monkeys.
Topics: Administration, Topical; Animals; Anterior Eye Segment; Disease Models, Animal; Glaucoma; Intraocula | 1992 |
B-B cell interactions in the spontaneous activation of B cells in autoimmune NZB mice.
Topics: Animals; Autoimmunity; B-Lymphocytes; Disease Models, Animal; Female; Immunoglobulin G; Lupus Vulgar | 1991 |
Experimental study on multidisciplinary treatment of pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Combined Modality Therapy; Cricetinae; Disease Model | 1990 |
Effect of concentration and time of drug exposure on clonal growth of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cisplatin; Colony-Forming Units Assay; Disease | 1985 |
Liver metastasis of colon 26 cells implanted into the superior mesenteric vein in mice.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Disease Models, Animal; Injections, Intravenous; Liver N | 1987 |