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mitomycin and Digestive System Neoplasms

mitomycin has been researched along with Digestive System Neoplasms in 13 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Digestive System Neoplasms: Tumors or cancer of the DIGESTIVE SYSTEM.

Research Excerpts

ExcerptRelevanceReference
"Intraperitoneal chemo-hyperthermia with mitomycin C was used to treat 28 patients with far advanced digestive adenocarcinoma and histologically confirmed peritoneal carcinomatosis."7.69Regional chemotherapy (with mitomycin C) and intra-operative hyperthermia for digestive cancers with peritoneal carcinomatosis. ( Banssillon, V; Bienvenu, J; Brachet, A; Burgard, G; Carry, PY; Gilly, FN; Guibert, B; Panteix, G; Salle, B; Sayag, AC, 1994)
"We have reported a 33% partial response rate with acceptable toxicity using weekly 24-h infusion of high-dose 5-fluorouracil (5-FU) and leucovorin (LV) in patients with far advanced biliary tract cancers (BTC)."5.09Mitomycin C with weekly 24-h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract and periampullar carcinomas. ( Chen, JS; Jan, YY; Liau, CT; Lin, YC, 2001)
"Intraperitoneal chemo-hyperthermia with mitomycin C was used to treat 28 patients with far advanced digestive adenocarcinoma and histologically confirmed peritoneal carcinomatosis."3.69Regional chemotherapy (with mitomycin C) and intra-operative hyperthermia for digestive cancers with peritoneal carcinomatosis. ( Banssillon, V; Bienvenu, J; Brachet, A; Burgard, G; Carry, PY; Gilly, FN; Guibert, B; Panteix, G; Salle, B; Sayag, AC, 1994)
" In the TBHT combined with anticancer chemotherapy, a partial remission was observed in 4 (25."1.27[Application of heat combined with antineoplastic agent administration in the treatment of cancer (with special reference to malignancy of the digestive system)]. ( Hamazoe, R; Izumi, A; Koga, S; Maeta, M; Shimizu, N, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's6 (46.15)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wagner, OJ1
Inglin, RA1
Bisch-Knaden, S1
Mettler, D1
Borner, M1
Candinas, D1
Egger, B1
Koga, S1
Shimizu, N1
Maeta, M1
Hamazoe, R1
Izumi, A1
Gilly, FN2
Carry, PY2
Sayag, AC2
Brachet, A2
Panteix, G2
Salle, B2
Bienvenu, J2
Burgard, G2
Guibert, B1
Banssillon, V2
Arinaga, S1
Karimine, N1
Adachi, M1
Inoue, H1
Nanbara, S1
Asoh, T1
Ueo, H1
Akiyoshi, T1
Baba, E1
Gutman, M1
Abu-Abid, S1
Sorkine, P1
Inbar, M1
Lev, D1
Chen, Z1
Oron, D1
Chaitchik, S1
Klausner, JM1
Nio, Y1
Nagami, H1
Tamura, K1
Tsubono, M1
Nio, M1
Sato, M1
Kawabata, K1
Hayashi, H1
Shiraishi, T1
Imai, S1
Tsuchitani, T1
Mizuta, J1
Nakagawa, M1
Fukumoto, M1
Chen, JS1
Lin, YC1
Jan, YY1
Liau, CT1
Manchon, M1
Aoki, Y1
Tabuse, Y1
Tanimura, H1
Katsumi, M1
Asae, M1
Ichimiya, G1
Imai, T1
Ooshima, K1
Kakihara, M1
Kashitani, M1
Soga, K1
Turuya, T1
Toshima, M1
Shibasaki, K1
Matugi, H1
Kawai, C1
Asakura, H1
Nashimoto, A1
Sasaki, J1
Kato, K1
Tsutsui, M1
Sano, M1
Akai, S1
Borisov, VI1
Mamontov, AS1
Ass, NIa1

Reviews

1 review available for mitomycin and Digestive System Neoplasms

ArticleYear
[Chemotherapy of tumors of the gastrointestinal tract].
    Sovetskaia meditsina, 1985, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Digestive System Neoplasms

1985

Trials

6 trials available for mitomycin and Digestive System Neoplasms

ArticleYear
Regional perfusion with hemofiltration (chemofiltration) for the treatment of patients with regionally advanced cancer.
    Cancer, 1996, Sep-01, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma

1996
Multi-institutional randomized clinical study on the comparative effects of intracavital chemotherapy alone versus immunotherapy alone versus immunochemotherapy for malignant effusion.
    British journal of cancer, 1999, Volume: 80, Issue:5-6

    Topics: Adjuvants, Immunologic; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplat

1999
Mitomycin C with weekly 24-h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract and periampullar carcinomas.
    Anti-cancer drugs, 2001, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Bilia

2001
Treatment of malignant peritoneal effusion in digestive and ovarian cancer.
    Medical oncology and tumor pharmacotherapy, 1992, Volume: 9, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplati

1992
[Clinical effect of combined chemotherapy with UFT, MMC and OK-432 in recurring or advanced cancer of the digestive organs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Digestive System Neo

1989
[Chemotherapy of tumors of the gastrointestinal tract].
    Sovetskaia meditsina, 1985, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Digestive System Neoplasms

1985

Other Studies

7 other studies available for mitomycin and Digestive System Neoplasms

ArticleYear
Sirolimus and intraoperative hyperthermic peritoneal chemoperfusion with mitomycin-C do not impair healing of bowel anastomoses.
    Transplant international : official journal of the European Society for Organ Transplantation, 2008, Volume: 21, Issue:6

    Topics: Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Cell Proliferation; Digestive System Ne

2008
[Application of heat combined with antineoplastic agent administration in the treatment of cancer (with special reference to malignancy of the digestive system)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:2 Pt 2

    Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Digestive System Neoplasms; Extracorporeal Ci

1983
Regional chemotherapy (with mitomycin C) and intra-operative hyperthermia for digestive cancers with peritoneal carcinomatosis.
    Hepato-gastroenterology, 1994, Volume: 41, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Analysis of Variance; Chemotherapy, Cancer, Regional Perfusion; Combine

1994
Cytotoxic cell function and phenotypic analysis of peripheral blood mononuclear cells in cancer patients treated with low-dose interleukin-2 and mitomycin C.
    Cancer immunology, immunotherapy : CII, 1993, Volume: 37, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytotoxicity, Immunologic; Digestive System Ne

1993
[Effects of IgG-Fc-mitomycin C conjugate on cancer cells].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1996, Volume: 71, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Digestive System Neoplasms; Humans; Immunoglobulin Fc Fragment

1996
[Two cases of digestive cancer demonstrated remarkable regression by hyperthermia with systemic chemotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Colonic N

1989
[Arterial infusion cancer chemotherapy in liver tumor using implantable reservoir].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

1989