mitomycin has been researched along with Di Guglielmo Disease in 10 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 54-year-old man with colon cancer underwent hemicolectomy." | 1.32 | Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer. ( Miyazaki, M; Nakamori, Y; Shinohara, K; Taguchi, A; Tominaga, T, 2003) |
| " Other CBR substrates such as menadione, phenanthrenequinone, and doxorubicin were equally toxic to both the CBR expresser cells and the control cells under the conditions tested." | 1.29 | Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells. ( Akman, S; Doroshow, J; Forrest, GL; Gonzalez, B; Kaplan, WD; Rivera, H, 1995) |
| "Treatment with mitomycin C at different times after dimethyl sulfoxide addition shows that cell sensitivity to inhibition is not homogeneous during the induction period; it is maximal between 18 and 24 h from the start of induction and is observed with a concentration of mitomycin C as low as 25 fM." | 1.27 | Inhibition of dimethyl sulfoxide induced erythropoietic differentiation of murine erythroleukemia cells in culture. ( Foresti, M; Gaudio, L; Geraci, G; Manduca, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamori, Y | 1 |
| Miyazaki, M | 1 |
| Tominaga, T | 1 |
| Taguchi, A | 1 |
| Shinohara, K | 1 |
| Kaku, M | 1 |
| Yagawa, K | 1 |
| Nakamura, K | 1 |
| Okano, H | 1 |
| Doll, DC | 1 |
| Weiss, RB | 1 |
| Gonzalez, B | 1 |
| Akman, S | 1 |
| Doroshow, J | 1 |
| Rivera, H | 1 |
| Kaplan, WD | 1 |
| Forrest, GL | 1 |
| Watanabe, T | 1 |
| Kume, T | 1 |
| Tsuneizumi, K | 1 |
| Kondo, K | 1 |
| Shiraishi, T | 1 |
| Oishi, M | 1 |
| Nakagawa, H | 1 |
| Tanaka, S | 1 |
| Takashima, T | 1 |
| Shizumi, Y | 1 |
| Nishigaki, H | 1 |
| Horiike, S | 1 |
| Taniwaki, M | 1 |
| Misawa, S | 1 |
| Kashima, K | 1 |
| Hironaka, T | 1 |
| Yamamoto, S | 1 |
| Hoon, DS | 1 |
| Chandler, P | 1 |
| Schmid, I | 1 |
| Irie, RF | 1 |
| Foresti, M | 1 |
| Gaudio, L | 1 |
| Geraci, G | 1 |
| Manduca, P | 1 |
| Ward, PE | 1 |
| McKenna, PG | 2 |
| McKelvey, VJ | 1 |
2 reviews available for mitomycin and Di Guglielmo Disease
| Article | Year |
|---|---|
Chemotherapeutic agents and the erythron.
Topics: Anemia, Hemolytic; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Erythrocyte Membra | 1983 |
Acute erythroleukemia with t(3;5) accompanied by hepatocellular carcinoma.
Topics: Aclarubicin; Adolescent; Adult; Aged; Anemia, Refractory, with Excess of Blasts; Carcinoma, Hepatoce | 1991 |
8 other studies available for mitomycin and Di Guglielmo Disease
| Article | Year |
|---|---|
Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, | 2003 |
Synthesis of adult-type hemoglobin in human erythremia cell line.
Topics: Cell Line; Cytarabine; Daunorubicin; Fetal Hemoglobin; Hemoglobins; Humans; Leukemia, Erythroblastic | 1984 |
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Antibiotics, Antineoplastic; Base | 1995 |
Synergistic induction of erythroid differentiation of mouse erythroleukemia (MEL) cells by inhibitors of topoisomerases and protein tyrosine kinases.
Topics: Acetamides; Amsacrine; Animals; Blotting, Western; Camptothecin; Cell Differentiation; Cinnamates; D | 1992 |
Generation of lymphokine-activated killer cell activity by low-dose recombinant interleukin-2 and tumor cells.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; Cells, Cultured; Cytotoxicity, | 1990 |
Inhibition of dimethyl sulfoxide induced erythropoietic differentiation of murine erythroleukemia cells in culture.
Topics: Animals; Benzidines; Cell Differentiation; Cells, Cultured; Chromatin; Dimethyl Sulfoxide; Erythropo | 1986 |
Mutation at the APRT locus in Friend erythroleukaemia cells. 2. Sensitivity to mitomycin C induced cytogenetic damage.
Topics: Adenine Phosphoribosyltransferase; Animals; Cell Line; Chromosome Aberrations; Clone Cells; DNA Dama | 1987 |
Enhanced synergism between caffeine and mitomycin C in the induction of cytogenetic aberrations in thymidine kinase-deficient Friend murine erythroleukaemia cells.
Topics: Animals; Caffeine; Cell Line; Chromosome Aberrations; Dose-Response Relationship, Drug; Drug Synergi | 1986 |