mitomycin has been researched along with Dermatitis, Radiation-Induced in 11 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Newer radiation techniques, and the application of continuous 5-FU exposure during radiation therapy using oral capecitabine may improve the treatment of anal cancer." | 5.17 | Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study. ( Beijnen, JH; Boot, H; Cats, A; Deenen, MJ; Dewit, L; Schellens, JH, 2013) |
| "Definitive chemoradiation with concurrent 5-fluorouracil (5-FU)/mitomycin C (MMC) is an effective treatment for localized anal cancer, but it is associated with significant acute long-term treatment-related toxicity." | 3.91 | Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study. ( Adams, J; Allen, JN; Baglini, C; Ben-Josef, E; Blaszkowsky, LS; Clark, JW; DeLaney, TF; Drapek, LC; Hong, TS; Jiang, W; Metz, JM; Murphy, JE; Parikh, AR; Plastaras, JP; Ryan, DP; Wo, JY; Yeap, BY, 2019) |
| "Rectal squamous cell carcinoma is a rare tumour; it management should be based on anal curative and conservative intent chemoradiation." | 2.53 | [Rectal squamous cell carcinoma treatment: Retrospective experience in two French university hospitals, review and proposals]. ( Bosset, JF; Huguet, F; Loganadane, G; Schernberg, A; Servagi-Vernat, S; Touboul, E, 2016) |
| "Grade 3-4 neutropenia was seen in 10/23 patients (43%)." | 1.46 | PET-CT guided SIB-IMRT combined with concurrent 5-FU/MMC for the treatment of anal cancer. ( Beer, J; Bodis, S; Oehler, C; Vlachopoulou, V; von Moos, R; Zimmermann, M; Zwahlen, DR, 2017) |
| "The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life." | 1.39 | Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013) |
| "Chemoradiation for anal cancer yields effective tumor control, but is associated with significant acute toxicity." | 1.38 | Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy. ( Blaszkowsky, LS; Coen, JJ; Hartshorn, K; Hong, TS; Kachnic, LA; Kwak, EL; Ryan, DP; Tsai, HK; Willins, JD, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 10 (90.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zimmermann, M | 1 |
| Beer, J | 1 |
| Bodis, S | 1 |
| von Moos, R | 1 |
| Vlachopoulou, V | 1 |
| Zwahlen, DR | 1 |
| Oehler, C | 1 |
| Wo, JY | 1 |
| Plastaras, JP | 1 |
| Metz, JM | 1 |
| Jiang, W | 1 |
| Yeap, BY | 1 |
| Drapek, LC | 1 |
| Adams, J | 1 |
| Baglini, C | 1 |
| Ryan, DP | 2 |
| Murphy, JE | 1 |
| Parikh, AR | 1 |
| Allen, JN | 1 |
| Clark, JW | 1 |
| Blaszkowsky, LS | 2 |
| DeLaney, TF | 1 |
| Ben-Josef, E | 1 |
| Hong, TS | 2 |
| Deenen, MJ | 1 |
| Dewit, L | 1 |
| Boot, H | 1 |
| Beijnen, JH | 1 |
| Schellens, JH | 1 |
| Cats, A | 1 |
| Doyen, J | 1 |
| Benezery, K | 1 |
| Follana, P | 1 |
| Ortholan, C | 2 |
| Gérard, JP | 1 |
| Hannoun-Levi, JM | 1 |
| Gal, J | 1 |
| Francois, E | 1 |
| Call, JA | 1 |
| Prendergast, BM | 1 |
| Jensen, LG | 1 |
| Ord, CB | 1 |
| Goodman, KA | 1 |
| Jacob, R | 1 |
| Mell, LK | 1 |
| Thomas, CR | 1 |
| Jabbour, SK | 1 |
| Miller, RC | 1 |
| Troussier, I | 1 |
| Huguet, F | 2 |
| Servagi-Vernat, S | 2 |
| Benahim, C | 1 |
| Khalifa, J | 1 |
| Darmon, I | 1 |
| Krebs, L | 1 |
| Dejean, C | 1 |
| Fenoglietto, P | 1 |
| Vieillot, S | 1 |
| Bensadoun, RJ | 1 |
| Thariat, J | 1 |
| Schernberg, A | 1 |
| Loganadane, G | 1 |
| Touboul, E | 1 |
| Bosset, JF | 1 |
| Wolff, HA | 1 |
| Raus, I | 1 |
| Jung, K | 1 |
| Schüler, P | 1 |
| Herrmann, MK | 1 |
| Hennies, S | 1 |
| Vorwerk, H | 1 |
| Hille, A | 1 |
| Hess, CF | 1 |
| Christiansen, H | 1 |
| Kachnic, LA | 1 |
| Tsai, HK | 1 |
| Coen, JJ | 1 |
| Hartshorn, K | 1 |
| Kwak, EL | 1 |
| Willins, JD | 1 |
| Robertson, B | 1 |
| Shepherd, L | 1 |
| Abratt, RP | 1 |
| Hunter, A | 1 |
| Goldberg, P | 1 |
| Dobrowsky, W | 1 |
| Naudé, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Feasibility Study of Definitive Concurrent Chemoradiation With Pencil Beam Scanning Proton Beam in Combination With 5-Fluorouracil and Mitomycin-C for Carcinoma of the Anal Canal[NCT01858025] | Early Phase 1 | 25 participants (Actual) | Interventional | 2013-07-31 | Active, not recruiting | ||
| A Phase II, Randomised Study of Nivolumab as Consolidation Therapy in Patients With Locally Advanced, Unresectable Non-Small Cell Lung Cancer (Stage III) Who Have Not Progressed Following Neoadjuvant Chemotherapy Plus Nivolumab and Definitive Concurrent C[NCT04085250] | Phase 2 | 264 participants (Actual) | Interventional | 2019-11-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mitomycin and Dermatitis, Radiation-Induced
| Article | Year |
|---|---|
[Rectal squamous cell carcinoma treatment: Retrospective experience in two French university hospitals, review and proposals].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcin | 2016 |
2 trials available for mitomycin and Dermatitis, Radiation-Induced
| Article | Year |
|---|---|
Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; C | 2013 |
Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Chi-Square Distribution; Combine | 2000 |
8 other studies available for mitomycin and Dermatitis, Radiation-Induced
| Article | Year |
|---|---|
PET-CT guided SIB-IMRT combined with concurrent 5-FU/MMC for the treatment of anal cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem | 2017 |
Pencil Beam Scanning Proton Beam Chemoradiation Therapy With 5-Fluorouracil and Mitomycin-C for Definitive Treatment of Carcinoma of the Anal Canal: A Multi-institutional Pilot Feasibility Study.
Topics: Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamou | 2019 |
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac | 2013 |
Intensity-modulated Radiation Therapy for Anal Cancer: Results From a Multi-Institutional Retrospective Cohort Study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape | 2016 |
[Management of locally advanced anal canal carcinoma with modulated arctherapy and concurrent chemotherapy].
Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell | 2015 |
High-grade acute organ toxicity as a positive prognostic factor in primary radiochemotherapy for anal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols | 2011 |
Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squam | 2012 |
Treatment of carcinoma of the anal canal at Groote Schuur Hospital.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neo | 2012 |