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mitomycin and Delayed Hypersensitivity

mitomycin has been researched along with Delayed Hypersensitivity in 24 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"To know the dermatologic side effects of intravesical treatment with Mitomycin C in non muscle invasive bladder cancer."7.83Dermatological side effects of intravesical Mitomycin C: Delayed hypersensitivity. ( Castillo Pacheco, C; Colomer Gallardo, A; González Satue, C; Ibarz Servio, L; Martínez Rodríguez, R, 2016)
"Primary outcome measurement was recurrence-free survival (RFS)."6.77Intracutaneous and intravesical immunotherapy with keyhole limpet hemocyanin compared with intravesical mitomycin in patients with non-muscle-invasive bladder cancer: results from a prospective randomized phase III trial. ( Caris, CT; Janzing-Pastors, MH; Lammers, RJ; Witjes, JA; Witjes, WP, 2012)
"To know the dermatologic side effects of intravesical treatment with Mitomycin C in non muscle invasive bladder cancer."3.83Dermatological side effects of intravesical Mitomycin C: Delayed hypersensitivity. ( Castillo Pacheco, C; Colomer Gallardo, A; González Satue, C; Ibarz Servio, L; Martínez Rodríguez, R, 2016)
"A 71-year-old man developed an exfoliative dermatitis of the palms of the hands and soles of the feet, and a generalized itch, during treatment with intravesical instillations of mitomycin C for an undifferentiated carcinoma of the bladder."3.70Type III and type IV hypersensitivity reactions due to mitomycin C. ( Bruynzeel, DP; Kunkeler, L; Nieboer, C, 2000)
"Primary outcome measurement was recurrence-free survival (RFS)."2.77Intracutaneous and intravesical immunotherapy with keyhole limpet hemocyanin compared with intravesical mitomycin in patients with non-muscle-invasive bladder cancer: results from a prospective randomized phase III trial. ( Caris, CT; Janzing-Pastors, MH; Lammers, RJ; Witjes, JA; Witjes, WP, 2012)
"Two lymphomas were found in, and isolated from A (H-2a) mice in which permanent transplantation tolerance was induced to CBA (H-2k) histocompatibility antigens by the neonatal injection of (CBAxA)F1 spleen cells."1.29MHC-specific graft-protective and delayed-type hypersensitivity (DTH) suppressive activity of a CD4+ CD8+, alpha beta T cell receptor (TCR) positive lymphoma isolated from a tolerant mouse. ( Baranyi, L; Benner, R; Jánossy, T; Knulst, AC; Végh, P; Vizler, C, 1993)
"Mitomycin C is an alkylating agent, used by intravesical instillation to treat carcinoma of the bladder."1.28Dermatitis due to intravesical mitomycin C: a delayed-type hypersensitivity reaction? ( Colver, GB; Hunter, JA; Inglis, JA; McVittie, E; Spencer, MJ; Tolley, DA, 1990)
"The growth of Meth A (MA) tumors was suppressed in tumor-antigen-specific manner in BALB/c mice immunized with mitomycin C-treated MA (MMC-MA) cells in saline or in Freund's complete adjuvant (FCA)."1.27Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells. ( Himeno, K; Matsumoto, T; Miake, S; Mitani, M; Mori, K; Nomoto, K, 1986)
"Mitomycin C was used as the chemotherapeutic agent and BCG as the immunopotentiating agent."1.26[Experimental study on local immunochemotherapy]. ( Fujita, Y; Imai, H; Kageyama, N; Kasuga, M; Majima, S; Sakita, M; Torii, T; Yamane, T, 1982)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's5 (20.83)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colomer Gallardo, A1
Martínez Rodríguez, R1
Castillo Pacheco, C1
González Satue, C1
Ibarz Servio, L1
Fernandez, DG1
Fernández, AF1
Vallejo, MS1
Osorio, JL1
Anguita, MJ1
Jimenez, AL1
Lammers, RJ1
Witjes, WP1
Janzing-Pastors, MH1
Caris, CT1
Witjes, JA1
Cao Avellaneda, E1
López López, AI1
Maluff Torres, A1
Jiménez, RM1
Escudero Bragante, JF1
López Cubillana, P1
Prieto González, A1
Pérez Albacete, M1
Ashour, HM1
Niederkorn, JY1
Kasuga, M2
Sakita, M2
Yamane, T2
Torii, T2
Tamai, M1
Kageyama, N2
Fujita, Y2
Majima, S2
Kearney, R1
Harrop, P1
Okabe, M1
Imai, R1
Morimoto, M1
Imai, H1
Balemans, LT1
Vegt, PD1
Steerenberg, PA1
De Boer, EC1
Van Swaaij, A1
De Vries, RE1
Van der Meijden, AP1
Den Otter, W1
Jánossy, T1
Baranyi, L1
Knulst, AC1
Vizler, C1
Benner, R2
Végh, P1
Echechipía, S1
Alvarez, MJ1
García, BE1
Olaguíbel, JM1
Rodriguez, A1
Lizaso, MT1
Acero, S1
Tabar, AI1
Tanigawa, T1
Gotoh, M1
Nagano, H1
Ota, H1
Fukuzaki, T1
Sakon, M1
Monden, M1
Kunkeler, L1
Nieboer, C1
Bruynzeel, DP1
Colver, GB1
Inglis, JA1
McVittie, E1
Spencer, MJ1
Tolley, DA1
Hunter, JA1
Fujii, T1
Sugita, N1
Kobayashi, Y1
Saito, K1
Iijima, H1
Matsunaga, K1
Ando, T1
Oguchi, Y1
Morita, I1
Yoshikumi, C1
Mitani, M2
Mori, K2
Himeno, K3
Nomoto, K3
Bianchi, AT1
Schilham, MW1
Young, P1
Lefkovits, I1
Tokuda, N1
Mayumi, H1
Gondo, H1
Fan, JL1
Matsumoto, T1
Miake, S1
Sewell, WA1
de Moerloose, PA1
McKimm-Breschkin, JL1
Vadas, MA1
Tamura, S1
Tanaka, H1
Kikuta, K1
Kobayashi, T1
Sato, H1
Sato, Y1
Abe, F1
Hayashi, M1
Horinishi, H1
Matsuda, A1
Ishizuka, M1
Umezawa, H1
Kreider, JW1
Howell, LE1
Bartlett, GL1

Trials

1 trial available for mitomycin and Delayed Hypersensitivity

ArticleYear
Intracutaneous and intravesical immunotherapy with keyhole limpet hemocyanin compared with intravesical mitomycin in patients with non-muscle-invasive bladder cancer: results from a prospective randomized phase III trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-20, Volume: 30, Issue:18

    Topics: Administration, Cutaneous; Administration, Intravesical; Aged; Disease-Free Survival; Female; Hemocy

2012

Other Studies

23 other studies available for mitomycin and Delayed Hypersensitivity

ArticleYear
Dermatological side effects of intravesical Mitomycin C: Delayed hypersensitivity.
    Archivos espanoles de urologia, 2016, Volume: 69, Issue:2

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; Humans; Hypersensitivity, Delayed; Mitomy

2016
Delayed hypersensitivity to Mitomycin C.
    Contact dermatitis, 2009, Volume: 61, Issue:4

    Topics: Antibiotics, Antineoplastic; Humans; Hypersensitivity, Delayed; Male; Middle Aged; Mitomycin; Skin T

2009
[Type IV hypersensitivity to intravesical mitomycin].
    Actas urologicas espanolas, 2005, Volume: 29, Issue:8

    Topics: Administration, Topical; Aged; Alkylating Agents; Humans; Hypersensitivity, Delayed; Male; Mitomycin

2005
Expansion of B cells is necessary for the induction of T-cell tolerance elicited through the anterior chamber of the eye.
    International archives of allergy and immunology, 2007, Volume: 144, Issue:4

    Topics: Adoptive Transfer; Animals; Anterior Chamber; Antigen-Presenting Cells; B-Lymphocytes; Cell Prolifer

2007
Intratumor chemoimmunotherapy with mitomycin C and BCG in C3H/He mice transplanted with MH134.
    Gan, 1983, Volume: 74, Issue:1

    Topics: Animals; Antibody Formation; BCG Vaccine; Hypersensitivity, Delayed; Immunotherapy; Lymphatic Metast

1983
Modulation of anti-tumour immunity induced by syngeneic mitomycin C-treated murine tumour cells.
    International journal of cancer, 1984, Aug-15, Volume: 34, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cross Reactions; Female; Graft Rejection; Hypersensitivity, Delayed; Im

1984
The action of 7-N-(p-hydroxyphenyl)mitomycin C [M-83] in suppressing murine immune response.
    The Journal of antibiotics, 1982, Volume: 35, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunos

1982
[Experimental study on local immunochemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; BCG Vaccine; Hemolytic Plaque Technique; Hypersensitivity, Del

1982
Effects of sequential intravesical administration of mitomycin C and bacillus Calmette-Guérin on the immune response in the guinea pig bladder.
    Urological research, 1994, Volume: 22, Issue:4

    Topics: Administration, Intravesical; Animals; Bacterial Adhesion; BCG Vaccine; Female; Guinea Pigs; Histoco

1994
MHC-specific graft-protective and delayed-type hypersensitivity (DTH) suppressive activity of a CD4+ CD8+, alpha beta T cell receptor (TCR) positive lymphoma isolated from a tolerant mouse.
    Immunobiology, 1993, Volume: 188, Issue:1-2

    Topics: Animals; Animals, Newborn; CD4 Antigens; CD8 Antigens; Cell Division; Flow Cytometry; Fluorescent An

1993
Generalized dermatitis due to mitomycin C patch test.
    Contact dermatitis, 1995, Volume: 33, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Drug Eruptions; Humans; Hypersensitivity, Delayed; Male; Mitomyci

1995
Injection of mitomycin-C-treated spleen cells induces donor-specific unresponsiveness to cardiac allografts in rats.
    Transplantation, 1999, Mar-15, Volume: 67, Issue:5

    Topics: Adoptive Transfer; Animals; Heart Transplantation; Hypersensitivity, Delayed; Male; Mitomycin; Preop

1999
Type III and type IV hypersensitivity reactions due to mitomycin C.
    Contact dermatitis, 2000, Volume: 42, Issue:2

    Topics: Administration, Intravesical; Aged; Antibiotics, Antineoplastic; Carcinoma; Dermatitis, Exfoliative;

2000
Dermatitis due to intravesical mitomycin C: a delayed-type hypersensitivity reaction?
    The British journal of dermatology, 1990, Volume: 122, Issue:2

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Alkylating Agents; Antigen-Presenting Cells;

1990
Treatment with Krestin combined with mitomycin C, and effect on immune response.
    Oncology, 1989, Volume: 46, Issue:1

    Topics: Animals; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Female; Hypersensitivit

1989
Anti-tumor cytostatic mechanism and delayed-type hypersensitivity against a syngeneic murine tumor. Comparison between neonatally thymectomized mice and congenitally athymic nude mice.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Mar-15, Volume: 142, Issue:6

    Topics: Animals; Animals, Newborn; Cell Division; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic

1989
In vivo priming of helper and suppressor T cells by alloantigens. Frequency analysis with the use of an in vitro limiting dilution assay.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Oct-15, Volume: 139, Issue:8

    Topics: Animals; Antibody Formation; Dose-Response Relationship, Immunologic; Hypersensitivity, Delayed; Imm

1987
Drug-induced in vitro tolerance to allogeneic antigens. II. Further analysis of in vitro-tolerized spleen cells in a fully allogeneic murine combination.
    Transplantation, 1988, Volume: 45, Issue:2

    Topics: Animals; Animals, Newborn; Crosses, Genetic; Cytotoxicity, Immunologic; Fluorouracil; Graft vs Host

1988
Differing contribution of various effector cells in the elimination of syngeneic or allogeneic cells.
    Journal of clinical & laboratory immunology, 1986, Volume: 19, Issue:2

    Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cells, Cultured; Cytotoxicity, Immunologic; Fib

1986
Pertussigen enhances antigen-driven interferon-gamma production by sensitized lymphoid cells.
    Cellular immunology, 1986, Volume: 97, Issue:2

    Topics: Animals; Antigen-Presenting Cells; Emetine; Female; Hypersensitivity, Delayed; In Vitro Techniques;

1986
Mechanism by which pertussis toxin breaks unresponsiveness of delayed-type hypersensitivity to sheep red blood cells in mice.
    Cellular immunology, 1986, Volume: 100, Issue:2

    Topics: Animals; Antigens, Ly; Erythrocytes; Female; Hypersensitivity, Delayed; Mice; Mice, Inbred C57BL; Mi

1986
Enhancement of graft-versus-host reaction and delayed cutaneous hypersensitivity in mice by ubenimex.
    The Journal of antibiotics, 1986, Volume: 39, Issue:8

    Topics: Adjuvants, Immunologic; Aging; Animals; Dose-Response Relationship, Drug; Graft vs Host Reaction; Hy

1986
Characteristics of T cells involved in the expression of delayed hypersensitivity and tumor rejection immunity to 13762A rat mammary adenocarcinoma.
    Cellular immunology, 1985, Volume: 93, Issue:1

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antigens, Surface; Cyclophosphamide; Female; Hydroxyure

1985