Page last updated: 2024-11-06

mitomycin and De Lange Syndrome

mitomycin has been researched along with De Lange Syndrome in 1 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

De Lange Syndrome: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vrouwe, MG1
Elghalbzouri-Maghrani, E1
Meijers, M1
Schouten, P1
Godthelp, BC1
Bhuiyan, ZA1
Redeker, EJ1
Mannens, MM1
Mullenders, LH1
Pastink, A1
Darroudi, F1

Other Studies

1 other study available for mitomycin and De Lange Syndrome

ArticleYear
Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair.
    Human molecular genetics, 2007, Jun-15, Volume: 16, Issue:12

    Topics: Cell Cycle Proteins; Cells, Cultured; Chromosome Aberrations; De Lange Syndrome; DNA Damage; DNA Rep

2007