Page last updated: 2024-11-06

mitomycin and Cystitis

mitomycin has been researched along with Cystitis in 29 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.

Research Excerpts

ExcerptRelevanceReference
"We performed a meta-analysis to evaluate the effect of intravesical mitomycin compared with gemcitabine on the treatment of non-muscle invasive bladder cancer."9.41Effect of intravesical mitomycin compared with gemcitabine on the treatment non-muscle invasive bladder cancer: A meta-analysis. ( Cheng, W; Chu, X; Huang, S; Zheng, H; Zheng, X; Zhou, Y, 2023)
"We compared intravesical instillations with mitomycin-C (MMC), Bacillus Calmette-Guerin (BCG) Tice, and BCG-RIVM in patients with pTa-pT1 papillary carcinoma and primary carcinoma in situ (CIS) of the bladder."9.07A randomised prospective study comparing intravesical instillations of mitomycin-C, BCG-Tice, and BCG-RIVM in pTa-pT1 tumours and primary carcinoma in situ of the urinary bladder. Dutch South-East Cooperative Urological Group. ( Debruyne, FM; Doesburg, W; Schaafsma, HE; vd Meijden, AP; Witjes, JA; Witjes, WP, 1993)
"Intravesical chemotherapy involving the sequential instillation of mitomycin C (MMC) and Adriamycin (ADM) was performed in 40 patients with superficial bladder cancer (pathological stages Ta and T1)."9.07Sequential instillation therapy with mitomycin C and adriamycin for superficial bladder cancer. ( Abe, K; Isaka, S; Okano, T; Shimazaki, J, 1992)
"Bladder retraction is a rare complication of contact chemotherapy with mitomycin C in the treatment of superficial bladder cancer."8.79[Bladder retraction, a complication of chemoprophylaxis of superficial bladder cancer using intravesical mitomycin C. Apropos of a case and review of the literature]. ( Hubert, J; Mangin, P; Punga-Maole, ML, 1995)
"Bladder wall calcification is a rare complication of intravesical therapy of superficial bladder cancer with Mitomycin C."7.68Incrusted cystitis after intravesical mitomycin C treatment. ( Algado, M; Botella, R; Llopis, M; Moreno, J, 1993)
"We analyzed 29 cases of eosinophilic cystitis in a group of 80 patients with lower urothelial carcinoma who had been treated with mitomycin-C."7.68[Eosinophilic cystitis as a special form of response to mitomycin C. Analysis and comments on our cases]. ( Arango Toro, O; Bielsa Galí, O; Corominas, J; Gelabert Mas, A; Lladó Carbonell, C; Vesa Llanes, J, 1991)
"During long periods of buffered instillations of mitomycin C (MMC) and doxorubicin (adriamycin; ADM) on carcinoma in situ (TIS), the complete response was 82% for MMC and 80% for ADM."7.67Effect of mitomycin C and doxorubicin instillation on carcinoma in situ of the urinary bladder. A Finnish multicenter study. ( Alfthan, O; Jauhiainen, K; Permi, J; Sotarauta, M, 1986)
"Twenty-three patients with histologically proven superficial bladder cancer (Tis, Ta, T1) were treated with intravesical instillations of Mitomycin C at a dose of 20 mg in 20 ml of water 3 times weekly for 21 instillations."7.66A phase II study of intravesical mitomycin C in the treatment of superficial bladder cancer. ( Green, DF; Harrison, GS; Newling, DW; Richards, B; Robinson, MR; Smith, PH, 1983)
"We performed a meta-analysis to evaluate the effect of intravesical mitomycin compared with gemcitabine on the treatment of non-muscle invasive bladder cancer."5.41Effect of intravesical mitomycin compared with gemcitabine on the treatment non-muscle invasive bladder cancer: A meta-analysis. ( Cheng, W; Chu, X; Huang, S; Zheng, H; Zheng, X; Zhou, Y, 2023)
"Mitomycin C (MMC) is a widely used agent for the adjuvant treatment of bladder tumors."5.35Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant! ( Cek, M; Fazlioglu, A; Kurtulus, FO; Parlakkilic, O; Tandogdu, Z, 2009)
"Eosinophilic cystitis is an unusual form of cystitis which is characterized by irritative voiding symptoms and haematuria."5.29Eosinophilic cystitis induced by mitomycin-C. ( Apaydin, E; Gürsan, A; Kandiloğlu, G; Ozyurt, C; Ulker, V, 1996)
"We compared intravesical instillations with mitomycin-C (MMC), Bacillus Calmette-Guerin (BCG) Tice, and BCG-RIVM in patients with pTa-pT1 papillary carcinoma and primary carcinoma in situ (CIS) of the bladder."5.07A randomised prospective study comparing intravesical instillations of mitomycin-C, BCG-Tice, and BCG-RIVM in pTa-pT1 tumours and primary carcinoma in situ of the urinary bladder. Dutch South-East Cooperative Urological Group. ( Debruyne, FM; Doesburg, W; Schaafsma, HE; vd Meijden, AP; Witjes, JA; Witjes, WP, 1993)
"Intravesical chemotherapy involving the sequential instillation of mitomycin C (MMC) and Adriamycin (ADM) was performed in 40 patients with superficial bladder cancer (pathological stages Ta and T1)."5.07Sequential instillation therapy with mitomycin C and adriamycin for superficial bladder cancer. ( Abe, K; Isaka, S; Okano, T; Shimazaki, J, 1992)
"Bladder retraction is a rare complication of contact chemotherapy with mitomycin C in the treatment of superficial bladder cancer."4.79[Bladder retraction, a complication of chemoprophylaxis of superficial bladder cancer using intravesical mitomycin C. Apropos of a case and review of the literature]. ( Hubert, J; Mangin, P; Punga-Maole, ML, 1995)
"Bladder wall calcification is a rare complication of intravesical therapy of superficial bladder cancer with Mitomycin C."3.68Incrusted cystitis after intravesical mitomycin C treatment. ( Algado, M; Botella, R; Llopis, M; Moreno, J, 1993)
"We analyzed 29 cases of eosinophilic cystitis in a group of 80 patients with lower urothelial carcinoma who had been treated with mitomycin-C."3.68[Eosinophilic cystitis as a special form of response to mitomycin C. Analysis and comments on our cases]. ( Arango Toro, O; Bielsa Galí, O; Corominas, J; Gelabert Mas, A; Lladó Carbonell, C; Vesa Llanes, J, 1991)
"During long periods of buffered instillations of mitomycin C (MMC) and doxorubicin (adriamycin; ADM) on carcinoma in situ (TIS), the complete response was 82% for MMC and 80% for ADM."3.67Effect of mitomycin C and doxorubicin instillation on carcinoma in situ of the urinary bladder. A Finnish multicenter study. ( Alfthan, O; Jauhiainen, K; Permi, J; Sotarauta, M, 1986)
"Three cases are presented in which eosinophilic cystitis developed when patients who were known to have superficial bladder cancer were treated with instillations of the alkylating agent Mitomycin C."3.67Allergy to mitomycin C complicating topical administration for urothelial cancer. ( Grigor, KM; Inglis, JA; Tolley, DA, 1987)
"Intravesical chemotherapy with sequential instillation of mitomycin C and adriamycin was carried out on 19 patients with superficial bladder cancer (Ta, T1 and Tis)."3.67[Sequential intravesical chemotherapy with mitomycin C and adriamycin for superficial bladder tumor (preliminary report)]. ( Fukui, I; Kihara, K; Sekine, H; Yamada, T, 1985)
"Twenty-three patients with histologically proven superficial bladder cancer (Tis, Ta, T1) were treated with intravesical instillations of Mitomycin C at a dose of 20 mg in 20 ml of water 3 times weekly for 21 instillations."3.66A phase II study of intravesical mitomycin C in the treatment of superficial bladder cancer. ( Green, DF; Harrison, GS; Newling, DW; Richards, B; Robinson, MR; Smith, PH, 1983)
"After ligation of ureters and urethra, male Sprague-Dawley rats were treated over 3 h with either 2 mg mitomycin C (MMC) intravesically (group I), or in conjunction with pre-instillation bladder electrocoagulation (group II) or iatrogenic Escherichia coli/xylene-induced severe cystitis (group III)."3.66Experimental investigations on the absorption of intravesically instilled mitomycin C in the urinary bladder of the rat. ( Bürger, R; Engelmann, U; Jacobi, GH, 1982)
"Mitomycin C (MMC) is a widely used agent for the adjuvant treatment of bladder tumors."1.35Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant! ( Cek, M; Fazlioglu, A; Kurtulus, FO; Parlakkilic, O; Tandogdu, Z, 2009)
"Eosinophilic cystitis is an unusual form of cystitis which is characterized by irritative voiding symptoms and haematuria."1.29Eosinophilic cystitis induced by mitomycin-C. ( Apaydin, E; Gürsan, A; Kandiloğlu, G; Ozyurt, C; Ulker, V, 1996)
"Mitomycin C is an alkylating agent, used by intravesical instillation to treat carcinoma of the bladder."1.28Dermatitis due to intravesical mitomycin C: a delayed-type hypersensitivity reaction? ( Colver, GB; Hunter, JA; Inglis, JA; McVittie, E; Spencer, MJ; Tolley, DA, 1990)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199012 (41.38)18.7374
1990's9 (31.03)18.2507
2000's4 (13.79)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Cheng, W1
Zhou, Y1
Chu, X1
Huang, S1
Zheng, X1
Zheng, H1
Cameo, MI1
Lezcano, MA1
Gil, D1
Blas, M1
Fazlioglu, A1
Tandogdu, Z1
Kurtulus, FO1
Parlakkilic, O1
Cek, M1
Caso, J1
Qin, D1
Sexton, WJ1
Wolff, HA1
Raus, I1
Jung, K1
Schüler, P1
Herrmann, MK1
Hennies, S1
Vorwerk, H1
Hille, A1
Hess, CF1
Christiansen, H1
Böhle, A1
Jocham, D1
Bock, PR1
Joselson, R1
Warnock, M1
Engelmann, U2
Oelsner, G1
Bürger, RA1
Wagner, H1
Niijima, T1
Koiso, K1
Akaza, H1
Harrison, GS1
Green, DF1
Newling, DW1
Richards, B1
Robinson, MR1
Smith, PH1
Schmidbauer, CP1
Porpaczy, P1
Georgopoulos, A1
Rameis, H1
Erdmann, WD1
Harzmann, R1
Flüchter, SH1
Bichler, KH1
Bürger, R1
Jacobi, GH1
Punga-Maole, ML1
Hubert, J1
Mangin, P1
Llopis, M1
Moreno, J1
Botella, R1
Algado, M1
Witjes, JA1
vd Meijden, AP1
Witjes, WP1
Doesburg, W2
Schaafsma, HE1
Debruyne, FM2
Ulker, V1
Apaydin, E1
Gürsan, A1
Ozyurt, C1
Kandiloğlu, G1
Cliff, AM1
Romaniuk, CS1
Parr, NJ1
Clark, T1
Chang, SS1
Cookson, MS1
Isaka, S1
Okano, T1
Abe, K1
Shimazaki, J1
Gelabert Mas, A2
Vesa Llanes, J1
Corominas, J1
Arango Toro, O1
Bielsa Galí, O1
Lladó Carbonell, C1
Dore, B1
Aubert, J1
Arango, O1
Rosales, A1
Coronado, J1
Moreno, A1
Colver, GB1
Inglis, JA2
McVittie, E1
Spencer, MJ1
Tolley, DA3
Hunter, JA1
van der Meijden, PM1
Steerenberg, PA1
de Jong, WH1
Jauhiainen, K1
Sotarauta, M1
Permi, J1
Alfthan, O1
Grigor, KM1
MacFarlane, JR1
Fukui, I1
Sekine, H1
Yamada, T1
Kihara, K1

Reviews

4 reviews available for mitomycin and Cystitis

ArticleYear
Effect of intravesical mitomycin compared with gemcitabine on the treatment non-muscle invasive bladder cancer: A meta-analysis.
    Actas urologicas espanolas, 2023, Volume: 47, Issue:2

    Topics: Administration, Intravesical; Cystitis; Deoxycytidine; Gemcitabine; Hematuria; Humans; Mitomycin; No

2023
Eosinophilic cystitis following immediate post-resection intravesical instillation of mitomycin-C.
    The Canadian journal of urology, 2010, Volume: 17, Issue:3

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; Cystitis; Eosinophilia; Female; Humans; M

2010
Intravesical bacillus Calmette-Guerin versus mitomycin C for superficial bladder cancer: a formal meta-analysis of comparative studies on recurrence and toxicity.
    The Journal of urology, 2003, Volume: 169, Issue:1

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Antibiotics, Antineoplastic; BCG Vaccine; Cyst

2003
[Bladder retraction, a complication of chemoprophylaxis of superficial bladder cancer using intravesical mitomycin C. Apropos of a case and review of the literature].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 1995, Volume: 5, Issue:4

    Topics: Administration, Intravesical; Aged; Chemoprevention; Cystitis; Humans; Male; Mitomycin; Urinary Blad

1995

Trials

4 trials available for mitomycin and Cystitis

ArticleYear
Randomized clinical trial on chemoprophylaxis of recurrence in cases of superficial bladder cancer.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Clinical Trials as Topic; Cystitis; Doxorubicin; Humans; Japan; Mitomycin; Mitomycins; Neoplasm Recu

1983
A randomised prospective study comparing intravesical instillations of mitomycin-C, BCG-Tice, and BCG-RIVM in pTa-pT1 tumours and primary carcinoma in situ of the urinary bladder. Dutch South-East Cooperative Urological Group.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:12

    Topics: Administration, Intravesical; Aged; BCG Vaccine; Carcinoma in Situ; Carcinoma, Transitional Cell; Cy

1993
Sequential instillation therapy with mitomycin C and adriamycin for superficial bladder cancer.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30 Suppl

    Topics: Administration, Intravesical; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cystitis;

1992
BCG-RIVM versus BCG-Tice versus mitomycin-C in superficial bladder cancer. Rationale and design of the trial of the Southeast Co-operative Urological Group, The Netherlands.
    Progress in clinical and biological research, 1989, Volume: 310

    Topics: Administration, Intravesical; BCG Vaccine; Carcinoma in Situ; Carcinoma, Papillary; Cystitis; Humans

1989

Other Studies

21 other studies available for mitomycin and Cystitis

ArticleYear
[Urinary tuberculosis caused by Mycobacterium bovis BCG variety, following intravesical instillation].
    Enfermedades infecciosas y microbiologia clinica, 2010, Volume: 28, Issue:2

    Topics: Administration, Intravesical; Aged; Antitubercular Agents; BCG Vaccine; Carcinoma, Transitional Cell

2010
Perivesical inflammation and necrosis due to mitomycin C instillation after transurethral resection of bladder tumor: we must be vigilant!
    Urologia internationalis, 2009, Volume: 83, Issue:3

    Topics: Administration, Intravesical; Aged; Anti-Bacterial Agents; Cystectomy; Cystitis; Humans; Male; Mitom

2009
High-grade acute organ toxicity as a positive prognostic factor in primary radiochemotherapy for anal carcinoma.
    International journal of radiation oncology, biology, physics, 2011, Apr-01, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2011
Pulmonary veno-occlusive disease after chemotherapy.
    Human pathology, 1983, Volume: 14, Issue:1

    Topics: Adult; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cystitis; Female; Humans; Lung; Mitomycin; Mi

1983
Permeability of the rat bladder to Cisplatinum under different conditions: comparison with Mitomycin C and Adriamycin.
    Urological research, 1983, Volume: 11, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Cisplatin; Cystitis; Doxorubicin; Electrocoagulation; Mitomyci

1983
A phase II study of intravesical mitomycin C in the treatment of superficial bladder cancer.
    British journal of urology, 1983, Volume: 55, Issue:6

    Topics: Carcinoma in Situ; Carcinoma, Transitional Cell; Cystitis; Drug Evaluation; Drug Implants; Erythema;

1983
Absorption of doxorubicin-hydrochloride and mitomycin-C after instillation into noninfected and infected bladders of dogs.
    The Journal of urology, 1984, Volume: 131, Issue:4

    Topics: Animals; Bacteriuria; Cystitis; Dogs; Doxorubicin; Male; Mitomycin; Mitomycins; Staphylococcal Infec

1984
[Local mitomycin-C therapy of infiltrating bladder cancer].
    Fortschritte der Medizin, 1984, Aug-16, Volume: 102, Issue:29-30

    Topics: Administration, Topical; Combined Modality Therapy; Cystitis; Humans; Mitomycin; Mitomycins; Neoplas

1984
Experimental investigations on the absorption of intravesically instilled mitomycin C in the urinary bladder of the rat.
    European urology, 1982, Volume: 8, Issue:3

    Topics: Absorption; Animals; Cystitis; Electrocoagulation; Escherichia coli Infections; Male; Mitomycin; Mit

1982
Incrusted cystitis after intravesical mitomycin C treatment.
    Acta urologica Belgica, 1993, Volume: 61, Issue:3

    Topics: Administration, Intravesical; Calcinosis; Carcinoma, Transitional Cell; Combined Modality Therapy; C

1993
Eosinophilic cystitis induced by mitomycin-C.
    International urology and nephrology, 1996, Volume: 28, Issue:6

    Topics: Administration, Intravesical; Biopsy; Carcinoma, Transitional Cell; Cystitis; Eosinophilia; Female;

1996
Perivesical inflammation after early mitomycin C instillation.
    BJU international, 2000, Volume: 85, Issue:4

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; Cystitis; Humans; Male; Middle Aged; Mito

2000
Eosinophilic cystitis presenting as a recurrent symptomatic bladder mass following intravesical mitomycin C therapy.
    The Journal of urology, 2002, Volume: 167, Issue:4

    Topics: Administration, Intravesical; Antibiotics, Antineoplastic; Cystitis; Eosinophilia; Humans; Male; Mid

2002
[Eosinophilic cystitis as a special form of response to mitomycin C. Analysis and comments on our cases].
    Archivos espanoles de urologia, 1991, Volume: 44, Issue:8

    Topics: Administration, Intravesical; Antigen-Antibody Complex; Carcinoma; Combined Modality Therapy; Cystit

1991
Re: Bladder wall calcification after intravesical mitomycin C treatment of superficial bladder cancer.
    The Journal of urology, 1991, Volume: 145, Issue:6

    Topics: Administration, Intravesical; Calcinosis; Cystitis; Humans; Mitomycin; Mitomycins; Urinary Bladder N

1991
Eosinophilic cystitis and allergy to mitomycin-C.
    Acta urologica Belgica, 1990, Volume: 58, Issue:3

    Topics: Aged; Antineoplastic Agents; Carcinoma, Transitional Cell; Cystitis; Eosinophilia; Female; Humans; M

1990
Dermatitis due to intravesical mitomycin C: a delayed-type hypersensitivity reaction?
    The British journal of dermatology, 1990, Volume: 122, Issue:2

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Alkylating Agents; Antigen-Presenting Cells;

1990
Effect of mitomycin C and doxorubicin instillation on carcinoma in situ of the urinary bladder. A Finnish multicenter study.
    European urology, 1986, Volume: 12, Issue:1

    Topics: Administration, Topical; Adult; Aged; Buffers; Carcinoma in Situ; Cystitis; Doxorubicin; Female; Hum

1986
Allergy to mitomycin C complicating topical administration for urothelial cancer.
    British journal of urology, 1987, Volume: 59, Issue:6

    Topics: Administration, Intravesical; Aged; Carcinoma, Transitional Cell; Cystitis; Drug Hypersensitivity; E

1987
Intravesical mitomycin C therapy for superficial bladder cancer. Report of a multicentre phase II study.
    British journal of urology, 1985, Volume: 57, Issue:1

    Topics: Carcinoma, Transitional Cell; Cystitis; Drug Evaluation; Humans; Mitomycin; Mitomycins; Skin Disease

1985
[Sequential intravesical chemotherapy with mitomycin C and adriamycin for superficial bladder tumor (preliminary report)].
    Hinyokika kiyo. Acta urologica Japonica, 1985, Volume: 31, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cystitis; Doxorubicin; Female; Humans;

1985