Page last updated: 2024-11-06

mitomycin and Contracture

mitomycin has been researched along with Contracture in 11 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Research Excerpts

ExcerptRelevanceReference
"To examine the use of Direct Visual Internal Urethrotomy with Mitomycin-C (DVIU-MMC) for bladder neck contracture and vesicourethral anastomotic stenosis in men who have undergone treatment for prostate cancer with radical prostatectomy and/or radiation therapy."8.12Outcomes of Vesicourethral Anastomotic Stenosis and Bladder Neck Contracture With Direct Visual Internal Urethrotomy With Mitomycin-C After Prostate Cancer Treatment. ( Hacker, EC; Maganty, A; Pere, MM; Rusilko, PJ, 2022)
"This study tested whether cell cycle inhibitor mitomycin C (MMC) prevents arthrogenic contracture progression during remobilization by inhibiting fibroblast proliferation and fibrosis in the joint capsule."7.96Intra-articular injection of mitomycin C prevents progression of immobilization-induced arthrogenic contracture in the remobilized rat knee. ( Kaneguchi, A; Ozawa, J; Yamaoka, K, 2020)
"To evaluate our longitudinal experience using visual internal urethrotomy (VIU) with intralesional mitomycin C (MMC) and short-term clean intermittent catheterization (CIC) for urethral strictures and bladder neck contractures (BNC) after failure of endoscopic management."7.81Visual Internal Urethrotomy With Intralesional Mitomycin C and Short-term Clean Intermittent Catheterization for the Management of Recurrent Urethral Strictures and Bladder Neck Contractures. ( Farrell, MR; Levine, LA; Sherer, BA, 2015)
"To examine the use of Direct Visual Internal Urethrotomy with Mitomycin-C (DVIU-MMC) for bladder neck contracture and vesicourethral anastomotic stenosis in men who have undergone treatment for prostate cancer with radical prostatectomy and/or radiation therapy."4.12Outcomes of Vesicourethral Anastomotic Stenosis and Bladder Neck Contracture With Direct Visual Internal Urethrotomy With Mitomycin-C After Prostate Cancer Treatment. ( Hacker, EC; Maganty, A; Pere, MM; Rusilko, PJ, 2022)
"To evaluate our longitudinal experience using visual internal urethrotomy (VIU) with intralesional mitomycin C (MMC) and short-term clean intermittent catheterization (CIC) for urethral strictures and bladder neck contractures (BNC) after failure of endoscopic management."3.81Visual Internal Urethrotomy With Intralesional Mitomycin C and Short-term Clean Intermittent Catheterization for the Management of Recurrent Urethral Strictures and Bladder Neck Contractures. ( Farrell, MR; Levine, LA; Sherer, BA, 2015)
"Mitomycin C at 6 mg/kg was given by continuous infusion through intraperitoneally implanted osmotic mini-pumps during CLDRI."1.28Early and late effects of mitomycin C and continuous low-dose-rate irradiation on the mouse skin and soft tissues of the leg. ( Fu, KK; Lam, KN, 1991)
"Most superficial bladder tumors are best treated by transurethral resection."1.27Severely contracted bladder following intravesical mitomycin C therapy. ( Englander, L; Huben, RP; McGill, W; Pontes, JE; Wajsman, Z, 1983)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Hacker, EC1
Maganty, A1
Pere, MM1
Rusilko, PJ1
Kaneguchi, A1
Ozawa, J1
Yamaoka, K1
Hassidim, A1
Sarna Cahan, S1
Tzur M D M H A, T1
Nava, MB1
Catanuto, G1
Rocco, N1
Farrell, MR2
Sherer, BA2
Levine, LA2
Voelzke, BB1
Mandour, SS1
Elmazar, HM1
Marey, HM1
Rahman, AK1
Sakr, RA1
Wajsman, Z1
McGill, W1
Englander, L1
Huben, RP1
Pontes, JE1
Fu, KK1
Lam, KN1
Baker, WC1
Russo, MA1
deVere White, RW1

Trials

1 trial available for mitomycin and Contracture

ArticleYear
Mucous Membrane Grafting Augmented with Topical Mitomycin C Application in Contracted Socket Repair Surgeries.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2016, Volume: 32, Issue:10

    Topics: Administration, Topical; Adult; Contracture; Female; Humans; Male; Mitomycin; Mucous Membrane; Ophth

2016

Other Studies

10 other studies available for mitomycin and Contracture

ArticleYear
Outcomes of Vesicourethral Anastomotic Stenosis and Bladder Neck Contracture With Direct Visual Internal Urethrotomy With Mitomycin-C After Prostate Cancer Treatment.
    Urology, 2022, Volume: 165

    Topics: Constriction, Pathologic; Contracture; Humans; Male; Mitomycin; Neoplasm Recurrence, Local; Prostate

2022
Intra-articular injection of mitomycin C prevents progression of immobilization-induced arthrogenic contracture in the remobilized rat knee.
    Physiological research, 2020, 02-19, Volume: 69, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Cell Proliferation; Contracture; Drug Evaluation, Preclinical;

2020
Role of Mitomycin C in Preventing Capsular Contracture in Implant-Based Reconstructive Breast Surgery: A Randomized Controlled Trial.
    Plastic and reconstructive surgery, 2017, Volume: 140, Issue:6

    Topics: Breast; Breast Implants; Contracture; Humans; Implant Capsular Contracture; Mitomycin

2017
Reply: Role of Mitomycin C in Preventing Capsular Contracture in Implant-Based Reconstructive Breast Surgery: A Randomized Controlled Trial.
    Plastic and reconstructive surgery, 2017, Volume: 140, Issue:6

    Topics: Breast; Breast Implants; Contracture; Humans; Implant Capsular Contracture; Mitomycin

2017
Visual Internal Urethrotomy With Intralesional Mitomycin C and Short-term Clean Intermittent Catheterization for the Management of Recurrent Urethral Strictures and Bladder Neck Contractures.
    Urology, 2015, Volume: 85, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Contracture; Humans; Injections, Intrales

2015
Editorial Comment.
    Urology, 2015, Volume: 85, Issue:6

    Topics: Contracture; Humans; Intermittent Urethral Catheterization; Male; Mitomycin; Urethra; Urethral Stric

2015
Reply: To PMID 26099892.
    Urology, 2015, Volume: 85, Issue:6

    Topics: Contracture; Humans; Intermittent Urethral Catheterization; Male; Mitomycin; Urethra; Urethral Stric

2015
Severely contracted bladder following intravesical mitomycin C therapy.
    The Journal of urology, 1983, Volume: 130, Issue:2

    Topics: Aged; Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Contracture; Humans; Male; Mitomyci

1983
Early and late effects of mitomycin C and continuous low-dose-rate irradiation on the mouse skin and soft tissues of the leg.
    International journal of radiation oncology, biology, physics, 1991, Volume: 21, Issue:6

    Topics: Acute-Phase Reaction; Animals; Connective Tissue; Contracture; Dose-Response Relationship, Radiation

1991
Severe bladder contracture in patient receiving intravesical mitomycin C for superficial bladder cancer.
    Urology, 1987, Volume: 30, Issue:4

    Topics: Administration, Intravesical; Carcinoma, Transitional Cell; Contracture; Female; Humans; Middle Aged

1987