mitomycin has been researched along with Colonic Neoplasms in 382 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined red cell fragmentation syndrome (RCFS) induced by mitomycin C (MMC) (13 patients), by thrombotic thrombocytopenic purpura (TTP) (17 patients), and by disseminated intravascular coagulation (DIC) (15 patients)." | 7.69 | Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C. ( Deguchi, K; Minami, N; Miyanishi, E; Nagaya, S; Oka, K; Tamaki, S; Tanigawa, M; Tsuzi, K; Wada, H; Wakita, Y, 1995) |
| "The interaction of photodynamic therapy (PDT) and a chemotherapeutic drug, mitomycin C (MMC), was investigated using WiDr human colon adenocarcinoma tumours implanted on Balb/c athymic nude mice." | 7.69 | Anti-tumour activity of photodynamic therapy in combination with mitomycin C in nude mice with human colon adenocarcinoma. ( Iani, V; Ma, LW; Moan, J; Steen, HB, 1995) |
| "The ability of lonidamine (LND), an energolytic derivative of indazole carboxylic acid, to modulate the cytotoxic activity of mitomycin C (MMC) and 1,3,bis(2-chloroethyl)-1-nitrosourea (BCNU) was investigated in two human adenocarcinoma cell lines (LoVo and HT29) expressing different sensitivity profiles to the drugs." | 7.69 | In vitro effect of lonidamine on the cytotoxicity of mitomycin C and BCNU in human colon adenocarcinoma cells. ( Bearzatto, A; Costa, A; Orlandi, L; Silvestrini, R; Villa, R; Zaffaroni, N, 1994) |
| "The effects of photodynamic therapy (PDT) alone and in combination with Mitomycin C (MMC) on WiDr cells, a human colon adenocarcinoma cell line, were investigated." | 7.68 | Potentiation of photodynamic therapy by mitomycin C in cultured human colon adenocarcinoma cells. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Steen, HB, 1993) |
| " The cytotoxicity and cytokinetic effects of Mitomycin C (MC) and/or photochemotherapy (PCT) in cultured human colon adenocarcinoma (WiDr) cells were investigated using colony formation to determine cell survival and DNA flow cytometry to analyze cell kinetics." | 7.68 | Cytotoxicity and cytokinetic effects of mitomycin C and/or photochemotherapy in a human colon adenocarcinoma cell line. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Rimington, C; Saether, H; Steen, HB, 1992) |
| "Flow cytometry (FCM) was used to investigate the effect of mitomycin C (MC) on the cellular uptake of Photofrin II (PII) in a cultured human colon adenocarcinoma cell line (WiDr)." | 7.68 | Effect of mitomycin C on the uptake of photofrin II in a human colon adenocarcinoma cell line. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Steen, HB, 1992) |
| "Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix." | 7.68 | Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990) |
| "After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome." | 7.67 | Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986) |
| "Baseline and mitomycin C (MMC)-induced sister chromatid exchanges (SCEs) in two human tumor cell lines (a colon tumor and a melanoma) and in a normal fibroblast cell line were analyzed and compared." | 7.66 | Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line. ( Au, WW; Hsu, TC; Li, S; Schmoyer, RL, 1982) |
| "Adverse events after HIPEC were estimated by common terminology criteria for adverse events version 5." | 5.91 | Comparative Study of Short-Term Efficacy and Safety of Mitomycin versus Lobaplatin for Hyperthermic Intraperitoneal Chemotherapy after Radical Surgery in Colorectal Cancer with High-Risk Factors for Peritoneal Carcinomatosis: A Propensity Score Matching A ( Guo, X; Li, Y; Lin, Y; Lv, J; Ruan, T; Shen, C; Tao, K; Wu, C; Xiang, F; Zeng, X, 2023) |
| "Valproic acid has been demonstrated to mediate cytotoxic effects against tumor cells by acting as a histone-deacetylase inhibitor." | 5.33 | Synergistic effects of valproic acid and mitomycin C in adenocarcinoma cell lines and fresh tumor cells of patients with colon cancer. ( Atmaca, A; Chow, KU; Friedmann, I; Jäger, E; Weidmann, E, 2006) |
| "Mitomycin C is a powerful antineoplastic agent." | 5.31 | Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome. ( Catalano, C; Fabbian, F; Gianesini, C, 2002) |
| " One patient with aggressive fibromatosis was treated with TNF alone (200 micrograms/m2, days 1-5 every third week) and 10 patients (four colon cancer, four head and neck cancer; one melanoma; one sarcoma) received mitomycin C (15 mg/m2, day 1) followed by TNF (60-180 micrograms/m2, days 1-3) every sixth week." | 5.08 | Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients. ( Gooding, W; Kirkwood, JM; Logan, TF; Shadduck, RK, 1996) |
| "In a randomized, multicenter study, 168 evaluable patients with colorectal adenocarcinoma at B2, C1 or C2 stages of the Dukes, Astler and Coller classification, were treated after radical surgery with BCG and 5-fluorouracil alone (regimen A) or in combination with hydroxyurea, methyl-CCNU and mitomycin C (regimen B)." | 5.05 | Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma. ( De Vecchis, L; Lagomarsino Caprino, MC; Mazzei, T; Periti, P; Popoli, P, 1984) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Three mouse cancer cell lines [CT26 mouse colon cancer cells, B16 melanoma cells and Lewis lung carcinoma (LLC)], 5 human carcinoma cell lines (human esophageal squamous cell carcinoma cell lines TE8 and HEC46 and the human pancreatic carcinoma cell lines PK-9, AsPC-1 and SUIT-2) and 5 chemotherapeutic agents [mitoxantrone (MIT), mitomycin C(MMC), 5-fluorouracil (5FU), camptothecin (CPT-11) and cisplatin (CDDP)] that are frequently used in a clinical setting for cancer treatment were utilized to investigate the surface expression level of calreticulin and HLA class I after exposure to chemotherapeutic agents." | 3.81 | The key role of calreticulin in immunomodulation induced by chemotherapeutic agents. ( Hirano, S; Kuroda, A; Kuwatani, T; Kyogoku, N; Maki, T; Miyauchi, K; Shichinohe, T; Takeuchi, S; Tsuchikawa, T; Wada, M; Yamamura, Y, 2015) |
| " Similarly, constitutive hTERT expression inhibited wild-type p53-dependent apoptosis in response to mitomycin C or 5-fluorouracil in HCT116 colon carcinoma cells carrying endogenous p53." | 3.73 | hTERT antagonizes p53-induced apoptosis independently of telomerase activity. ( Latonen, L; Rahman, R; Wiman, KG, 2005) |
| " In the present study, the antitumour activity, pharmacokinetics and metabolism of mitomycin C (MMC) has been determined in vivo in two murine adenocarcinomas of the colon, MAC 16 (high DT-diaphorase activity) and MAC 26 (low DT-diaphorase activity) after intra-tumoural injection of drug." | 3.70 | Pharmacological determinants of the antitumour activity of mitomycin C. ( Cummings, J; Ritchie, AA; Smyth, JF; Spanswick, VJ, 1998) |
| " In this study, a colchicine resistant subline (HCA-2/1cch) was selected from a human colon adenocarcinoma after a short period of drug exposure, as an in vitro model of drug resistance selection." | 3.70 | Multidrug resistance increment in a human colon carcinoma cell line by colchicine. ( Gil, L; Martínez Morillo, M; Ruiz Gómez, MJ; Souviron, A, 2000) |
| "We examined red cell fragmentation syndrome (RCFS) induced by mitomycin C (MMC) (13 patients), by thrombotic thrombocytopenic purpura (TTP) (17 patients), and by disseminated intravascular coagulation (DIC) (15 patients)." | 3.69 | Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C. ( Deguchi, K; Minami, N; Miyanishi, E; Nagaya, S; Oka, K; Tamaki, S; Tanigawa, M; Tsuzi, K; Wada, H; Wakita, Y, 1995) |
| "The interaction of photodynamic therapy (PDT) and a chemotherapeutic drug, mitomycin C (MMC), was investigated using WiDr human colon adenocarcinoma tumours implanted on Balb/c athymic nude mice." | 3.69 | Anti-tumour activity of photodynamic therapy in combination with mitomycin C in nude mice with human colon adenocarcinoma. ( Iani, V; Ma, LW; Moan, J; Steen, HB, 1995) |
| "The ability of lonidamine (LND), an energolytic derivative of indazole carboxylic acid, to modulate the cytotoxic activity of mitomycin C (MMC) and 1,3,bis(2-chloroethyl)-1-nitrosourea (BCNU) was investigated in two human adenocarcinoma cell lines (LoVo and HT29) expressing different sensitivity profiles to the drugs." | 3.69 | In vitro effect of lonidamine on the cytotoxicity of mitomycin C and BCNU in human colon adenocarcinoma cells. ( Bearzatto, A; Costa, A; Orlandi, L; Silvestrini, R; Villa, R; Zaffaroni, N, 1994) |
| "Pharmacokinetics and metabolism of mitomycin C (MMC) have been studied in NMRI mice bearing MAC 16 colon adenocarcinoma after direct intratumoural injection of either 500 micrograms free MMC or the same dose incorporated in albumin microspheres." | 3.69 | Encapsulation of mitomycin C in albumin microspheres markedly alters pharmacokinetics, drug quinone reduction in tumour tissue and antitumour activity. Implications for the drugs' in vivo mechanism of action. ( Allan, L; Cummings, J; Smyth, JF, 1994) |
| "In this study, the enzymology of mitomycin C (MMC) bioactivation in two murine colon adenocarcinomas, MAC 16 and MAC 26, was examined." | 3.69 | Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase. ( Cummings, J; Smyth, JF; Spanswick, VJ, 1996) |
| " In order to evaluate the HDRA with the 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide end point for clinical use, chemosensitivity to mitomycin C, doxorubicin, 5-fluorouracil, and cisplatin of 107 advanced gastric and 109 advanced colorectal cancers was determined in vitro in a correlative clinical trial." | 3.69 | Clinical applications of the histoculture drug response assay. ( Furukawa, T; Hoffman, RM; Kubota, T, 1995) |
| "The three-dimensional growth of cultured tumor cell lines (HT29, a colon adenocarcinoma cell line; M21, a melanoma cell line; KB, a nasopharyngeal carcinoma cell line) has been investigated in an agar culture system with a fibrin matrix in vitro." | 3.68 | Morphologic analysis of three-dimensional tumors developed in fibrin matrix and agar culture system. ( Hess, M; Koldovsky, P; Kumazawa, H, 1993) |
| "The effects of photodynamic therapy (PDT) alone and in combination with Mitomycin C (MMC) on WiDr cells, a human colon adenocarcinoma cell line, were investigated." | 3.68 | Potentiation of photodynamic therapy by mitomycin C in cultured human colon adenocarcinoma cells. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Steen, HB, 1993) |
| " The cytotoxicity and cytokinetic effects of Mitomycin C (MC) and/or photochemotherapy (PCT) in cultured human colon adenocarcinoma (WiDr) cells were investigated using colony formation to determine cell survival and DNA flow cytometry to analyze cell kinetics." | 3.68 | Cytotoxicity and cytokinetic effects of mitomycin C and/or photochemotherapy in a human colon adenocarcinoma cell line. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Rimington, C; Saether, H; Steen, HB, 1992) |
| "Flow cytometry (FCM) was used to investigate the effect of mitomycin C (MC) on the cellular uptake of Photofrin II (PII) in a cultured human colon adenocarcinoma cell line (WiDr)." | 3.68 | Effect of mitomycin C on the uptake of photofrin II in a human colon adenocarcinoma cell line. ( Berg, K; Ma, LW; Moan, J; Peng, Q; Steen, HB, 1992) |
| "Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix." | 3.68 | Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990) |
| "Fourteen cases of adenocarcinoma with pleuritis carcinomatosa (lung cancer 10 cases, ovarian cancer 2 cases, colon cancer 2 cases) were treated with intra-pleural instillation of 7-N-(p-hydroxyphenyl)-mitomycin C (KW-2083), a derivative of mitomycin C." | 3.67 | [Effect of 7-N-(P-hydroxyphenyl)-mitomycin C (KW-2083) against pleuritis carcinomatosa]. ( Eguchi, K; Garcia-Herreros, P; Hoshi, A; Nomori, H; Saijo, N; Sasaki, Y; Shimizu, E; Shinkai, T; Tominaga, K, 1984) |
| " Following our former report in which the combination effects of mitomycin C (MMC) and 5'-deoxy-5-fluorouridine (5'-DFUR) were clarified, combined applications of 4 drugs, vindesine (VDS), methotrexate (MTX), cisplatin (CDDP) and 5'-DFUR against 3 lines of human breast cancer (H-62, H-31, H-71), and one line each of gastric cancer (H-55) and colon cancer (H-110) xenografted into nude mice were evaluated in comparison with CAF (cyclophosphamide, adriamycin and 5-FU) therapy which is commonly used for breast cancer." | 3.67 | [Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)]. ( Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T, 1987) |
| " In our previous studies with human gastrointestinal and breast cancers xenografted into nude mice, combination therapy with mitomycin C (MMC) and 5'-deoxy-5-fluorouridine (5'-DFUR) [I] or cisplatin (CDDP), vindesine (VDS) and 5'-DFUR [II] produced higher response rates than single-agent therapy with any one of these drugs." | 3.67 | [Effects of alternating chemotherapy with 2 non-cross-resistant drug combinations on human alimentary and breast cancer xenografts in nude mice]. ( Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T; Yamauchi, T, 1987) |
| "After treatment with mitomycin C, a patient developed pulmonary hypertension with interstitial infiltrates, microangiopathic hemolytic anemia, systemic hypertension, and renal failure with the nephrotic syndrome." | 3.67 | Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome. ( McCarthy, JT; Staats, BA, 1986) |
| "Bestatin enhanced the antitumor effects of mitomycin C, 5-fluorouracil and cis-dichlorodiammineplatinum against a syngeneic solid tumor of colon adenocarcinoma 26 in BALB/c mice." | 3.67 | Enhancement of antitumor effect of cytotoxic agents by bestatin. ( Abe, F; Ashizawa, J; Horinishi, H; Ishizuka, M; Matsuda, A; Shibuya, K; Takahashi, K; Takeuchi, T; Umezawa, H, 1985) |
| "Lethal effects of mitomycin C (MMC), 4-nitroquinoline 1-oxide (4NQO) and ultraviolet light (UV) on fibroblast cell lines derived from a colon cancer-prone substrain of Wistar-Furth rats (WF/OSAKA rats) were measured in terms of the cellular colony-forming ability, and compared with the sensitivity to these agents of human fibroblasts from patients with adenomatosis coli and rectum (ACR)." | 3.66 | Increased sensitivity of cultured fibroblasts from colon cancer-prone rats to cytotoxicity of carcinogens and to viral transformation: a comparison with fibroblasts from patients with adenomatosis coli. ( Ikenaga, M; Kitamura, H; Miyamoto, M; Tsujimura, T; Utsunomiya, J, 1983) |
| "Baseline and mitomycin C (MMC)-induced sister chromatid exchanges (SCEs) in two human tumor cell lines (a colon tumor and a melanoma) and in a normal fibroblast cell line were analyzed and compared." | 3.66 | Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line. ( Au, WW; Hsu, TC; Li, S; Schmoyer, RL, 1982) |
| "The median (range) peritoneal carcinomatosis index was 13 (3-20) requiring a median operative time of 6." | 2.78 | A phase I trial of thermal sensitization using induced oxidative stress in the context of HIPEC. ( Harrison, LE; Razavi, R; Tiesi, G; Wang, CC, 2013) |
| "Stage III colon cancer patients were enrolled and were divided into two groups: Group W, in which the histologic type of both primary tumors and metastatic lymph nodes was well-differentiated adenocarcinoma; and Group U, in which the primary tumors and the metastatic lymph nodes were of any type other than well-differentiated." | 2.72 | Significance of histologic type of primary lesion and metastatic lymph nodes as a prognostic factor in stage III colon cancer. ( Hirota, T; Kodaira, S; Mori, T; Ohashi, Y, 2006) |
| "A retrospective study of 46 patients treated for peritoneal carcinomatosis from colon adenocarcinoma was performed." | 2.71 | Cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy for peritoneal carcinomatosis arising from colon adenocarcinoma. ( Campana, L; Foletto, M; Lise, M; Mocellin, S; Nitti, D; Pilati, P; Rossi, CR, 2003) |
| "A total of 760 patients with colon cancer and 669 patients with rectal cancer were entered into this randomized clinical trial (RCT)." | 2.71 | Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu ( Hojyo, K; Isomoto, H; Kato, T; Kodaira, S; Kunii, Y; Kunitomo, K; Niimoto, M; Nishida, O; Ohashi, Y; Takahashi, T; Tominaga, T; Watanabe, M; Yasutomi, M, 2004) |
| "Of 104 patients with peritoneal carcinomatosis from colon or rectal adenocarcinoma, five patients (4." | 2.69 | Treatment of primary colon cancer with peritoneal carcinomatosis: comparison of concomitant vs. delayed management. ( Pestieau, SR; Sugarbaker, PH, 2000) |
| "To assess the clinical effect and safety of Shenqi Fuzheng Injection (SQFZI) combined with chemotherapy in treating malignant tumor of digestive tract." | 2.69 | [Clinical study on Shenqi Fuzheng injection combined with chemotherapy in treating malignant tumor of digestive tract]. ( Wang, J; Xin, M; Zhou, C, 1998) |
| "To evaluate the efficacy of intra-arterial chemotherapy combined with hyperthermia for metastatic liver cancer, our cooperative study group carried out a randomized clinical trial comparing intra-arterial chemotherapy alone and intra-arterial chemotherapy combined with hyperthermia." | 2.68 | [A prospective randomized clinical trial comparing intra-arterial chemotherapy alone and when combined with hyperthermia for metastatic liver cancer]. ( Hiraoka, M; Itani, K; Kondo, M; Miura, K; Noguchi, M; Tanaka, Y; Watanabe, N; Yoshikawa, T, 1995) |
| "The regimens for colon cancer were, Arm I: mitomycin C [intraoperative portal vein bolus (12 mg/m2) + postoperative, twice weekly and then three times bimonthly for six months intermittent i." | 2.68 | Five-year results of a randomized controlled trial of adjuvant chemotherapy for curatively resected colorectal carcinoma. The Colorectal Cancer Chemotherapy Study Group of Japan. ( , 1995) |
| "For the local recurrence of rectal cancer, it was observed in Dukes C and cases of relative curative resection." | 2.68 | [Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan]. ( Kikuchi, K; Kunii, Y, 1995) |
| "5-FU; and arm III was surgery only." | 2.68 | Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy. ( Hamano, K; Kato, T; Kodaira, S; Koyama, Y; Ogawa, N; Sakabe, T; Takahashi, T; Tominaga, T; Yasutomi, M, 1996) |
| "Some 978 patients with colon cancer and 713 patients with rectal cancer were enrolled in the study, 85 (5." | 2.68 | [Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer]. ( Hojo, K; Ichihashi, H; Kato, T; Kikuchi, K; Kodaira, S; Kunii, Y; Ogawa, M; Takahashi, T; Tamada, R; Tominaga, T; Yasutomi, M, 1997) |
| "In collaboration with 428 institutions nation-wide, comparative studies on the optimal daily dosage of UFT were carried out for non-curative resection cases of colorectal cancer for two years from January 1984 to December 1985." | 2.67 | [Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Komi, N; Kondo, T; Maehara, Y; Sugimachi, K; Taguchi, T; Uchino, J, 1993) |
| "Five-year survival was 82." | 2.67 | [Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT]. ( Gotoda, H; Kinami, Y; Miyazaki, I; Saito, H; Takashima, S; Tomita, F; Yamaguchi, A, 1991) |
| "Patients (1,256 with colon cancer, 1,221 with rectal cancer) were divided into the treatment group (group A) and the control group (surgical resection only, group B)." | 2.66 | [Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kikuchi, K; Kodaira, S; Komi, N; Kondo, T; Ogawa, N; Taguchi, T; Uchino, J, 1989) |
| "The group of research for colorectal cancer treatments-Kajitani-group (chief T." | 2.66 | [Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials]. ( Hojo, K; Kajitani, T, 1986) |
| " No serious adverse effects were observed in any of the groups." | 2.66 | [Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Kunii, Y; Ogawa, N; Taguchi, T, 1987) |
| "In the colon cancer patients, 5-year survival rates were 88." | 2.66 | [Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku]. ( Kinami, Y; Miyazaki, I; Takashima, S, 1988) |
| "The rate of local recidivation in colon cancer resected curatively was higher in ACNU + FT group than in FT only group (p less than 0." | 2.66 | [A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan]. ( Abe, O; Hattori, T; Inokuchi, K; Kasai, Y; Kikuchi, K; Komi, N; Kondo, T; Niimoto, M; Ogawa, N; Taguchi, T, 1988) |
| "Adjuvant therapy of colorectal cancer with oral fluorinated pyrimidines is attractive because of its ease of administration and good tolerability." | 2.42 | Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials. ( Burzykowski, T; Buyse, M; Hamada, C; Ohashi, Y; Piedbois, P; Sakamoto, J, 2004) |
| "Sixty-six patients with colorectal cancer were studied regarding effects of prevention of hepatic recurrence in completely performed portal infusion chemotherapy." | 2.40 | [Is portal infusion chemotherapy uneffective for hepatic recurrence after resection for colorectal cancer?]. ( Akaishi, O; Tsukikawa, S; Yabe, K; Yamaguchi, S; Yamamura, T, 1999) |
| "For Dukes' C colon cancer, postoperative adjuvant chemotherapy with a combination of fluorouracil and levamisole is now recommended as standard therapy." | 2.39 | Adjuvant postoperative therapy of gastrointestinal malignancies. ( Ilson, DH; Kelsen, DP, 1994) |
| "In order to better understand colon cancer, a model system reflecting the heterogenous nature of this disease was developed and used in the development of new cytotoxic and non-cytotoxic therapeutic approaches." | 2.37 | Heterogeneity of human colon carcinoma. ( Brattain, MG; Chakrabarty, S; Levine, AE; Long, B; Willson, JK; Yeoman, LC, 1984) |
| "The sensitivity of various human tumors xenografted to nude mice has been tested to antitumor agents to establish the system which could select the clinically active drugs." | 2.37 | [Recent advanced studies on mitomycins, antitumor activity and mode of action]. ( Morimoto, M; Taguchi, T, 1987) |
| "Adverse events after HIPEC were estimated by common terminology criteria for adverse events version 5." | 1.91 | Comparative Study of Short-Term Efficacy and Safety of Mitomycin versus Lobaplatin for Hyperthermic Intraperitoneal Chemotherapy after Radical Surgery in Colorectal Cancer with High-Risk Factors for Peritoneal Carcinomatosis: A Propensity Score Matching A ( Guo, X; Li, Y; Lin, Y; Lv, J; Ruan, T; Shen, C; Tao, K; Wu, C; Xiang, F; Zeng, X, 2023) |
| "IPC in patients with T4 colon cancer can reduce the expression and proliferative potential of free cancer cells." | 1.56 | [Effectiveness of intraperitoneal chemotherapy for t4 colon cancer]. ( Achkasov, SI; Muratov, II; Saifutdinova, KR; Shakhmatov, DG; Shelygin, YA; Sukhina, MA; Sushkov, OI, 2020) |
| " An increasing dosage of TN (from 0." | 1.51 | Comparing the cytotoxicity of taurolidine, mitomycin C, and oxaliplatin on the proliferation of in vitro colon carcinoma cells following pressurized intra-peritoneal aerosol chemotherapy (PIPAC). ( Arafkas, M; Chaudhry, H; Khosrawipour, T; Khosrawipour, V; Knoefel, WT; Pigazzi, A; Schubert, J, 2019) |
| "Chemosensitivity of 5-Fu and MMC in colon cancer cells were tested by cell counting kit-8 (CCK-8) method." | 1.48 | Formyl peptide receptor 2 mediated chemotherapeutics drug resistance in colon cancer cells. ( Ge, YB; Peng, JM; Su, LD, 2018) |
| "For this study, human colon cancer LS174T, LS180, HCT116 and CX-1 cells were infected with secretory TRAIL-armed adenovirus (Ad." | 1.40 | Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells. ( Bartlett, DL; Kim, SY; Kwon, YT; Lee, DH; Lee, YJ; Song, X, 2014) |
| "Severe obesity is associated with decreased long-term survival only in patients with LGA primary disease; however, application of CRS/HIPEC still offers meaningful prolongation of life." | 1.39 | Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors. ( Levine, EA; Randle, RW; Shen, P; Stewart, JH; Swett, KR; Swords, DS; Votanopoulos, KI, 2013) |
| "When treated with mitomycin C, p53-deficient cells, but not p53-expressing cells, showed a marked increase in ceramide levels." | 1.38 | DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells. ( Duerksen-Hughes, PJ; Filippov, V; Filippova, M; Haynes, TA; Yang, J; Zhang, K, 2012) |
| "Human and murine colon cancer cell lines were subjected to mild hyperthermia (40-42°C), and treated with chemotherapy, similar to clinical protocols." | 1.38 | New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models. ( Clavien, PA; Gertsch, P; Graf, R; Humar, B; Jang, JH; Lehmann, K; Oberkofler, CE; Rickenbacher, A; von Boehmer, L; Vonlanthen, R, 2012) |
| "Using colon cancer cells, we found that AKR1B10 was induced with acquisition of resistance to the anticancer drug mitomycin-c (MMC)." | 1.37 | Involvement of the aldo-keto reductase, AKR1B10, in mitomycin-c resistance through reactive oxygen species-dependent mechanisms. ( Banno, Y; El-Kabbani, O; Endo, S; Hara, A; Iida, K; Matsunaga, T; Yamane, Y, 2011) |
| "Surgical cytoreduction of peritoneal surface malignancy of colorectal origin in combination with hyperthermic intraoperative peritoneal chemotherapy (HIPEC) has become an established treatment approach." | 1.36 | Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model. ( Atanassow, V; Braumann, C; Caldenas, S; Hartmann, J; Kilian, M; Makareinis, A; Raue, W; Schwenk, W, 2010) |
| "Patients with liver cancer were examined with diffusion-weighted MRI at two b values (0 and 500 s/mm(2)) before and after chemoemblization." | 1.35 | [Water mobility of diffusion MRI in prediction of response to chemoembolization in liver cancer]. ( Dong, S; Sun, ZC; Xiao, XS; Xu, LC; Ye, XD; Yuan, Z, 2009) |
| "Human colon cancer cell lines (HT-29, Caco-2, and DLD-1) were incubated with 5-FU and with 5-FU combined with cisplatin, camptothecin, paclitaxel, mitomycin C, interferon, or TNF-related apoptosis-inducing ligand." | 1.33 | Influence of chemotherapeutic agents and cytokines on the expression of 5-fluorouracil-associated enzymes in human colon cancer cell lines. ( Matsui, H; Matsuzaki, Y; Miyazaki, K; Nakahara, A; Sato, D; Shibahara, T; Suzuki, H; Uchida, K; Yanaka, A, 2006) |
| "Coculture assays of colon cancer cells and Jurkat cells (Fas-sensitive cells) were performed to observe the counterattack of colon cancer cells to lymphocytes." | 1.33 | Influence of antitumor drugs on the expression of Fas system in SW480 colon cancer cells. ( Cui, Y; Li, YQ; Liu, JY; Qin, CY; Wang, HB; Xu, HW; Yang, CM; Zhang, AZ; Zhu, Q, 2006) |
| "Valproic acid has been demonstrated to mediate cytotoxic effects against tumor cells by acting as a histone-deacetylase inhibitor." | 1.33 | Synergistic effects of valproic acid and mitomycin C in adenocarcinoma cell lines and fresh tumor cells of patients with colon cancer. ( Atmaca, A; Chow, KU; Friedmann, I; Jäger, E; Weidmann, E, 2006) |
| "No Mitomycin C was added in control group." | 1.32 | The study of chemiluminescence in gastric and colonic carcinoma cell lines treated by anti-tumor drugs. ( Chen, C; Li, JS; Liu, FK; Qi, XP, 2003) |
| "A 54-year-old man with colon cancer underwent hemicolectomy." | 1.32 | Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer. ( Miyazaki, M; Nakamori, Y; Shinohara, K; Taguchi, A; Tominaga, T, 2003) |
| "Prognosis was poorer for patients with colon cancer, who had a median survival of 7." | 1.32 | Total abdominal colectomy, pelvic peritonectomy, and end-ileostomy for the surgical palliation of mucinous peritoneal carcinomatosis from non-gynecologic cancer. ( Karakozis, S; Stamou, KM; Sugarbaker, PH, 2003) |
| "Bioluminescent PC-3M-luc-C6 human prostate cancer cells were implanted subcutaneously into SCID-beige mice and were monitored for tumor growth and response to 5-FU and mitomycin C treatments." | 1.32 | Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis. ( Contag, PR; Dusich, J; Hornig, YS; Jenkins, DE; Oei, Y; Purchio, T; Yu, SF, 2003) |
| " In order to promote the clinical response of chemotherapy for colorectal cancer using CPT-11, one of the most effective strategies is to use it in combination with other anticancer agents." | 1.31 | In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer. ( Hotta, T; Ishimoto, K; Iwahashi, M; Matsuda, K; Tanaka, H; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H, 2000) |
| "Mitomycin C was one of the first chemotherapeutic agents to be shown to have preferential cytotoxicity toward hypoxic cells in vitro." | 1.31 | Effects of mitomycin C on the oxygenation and radiosensitivity of murine and human tumours in mice. ( Durand, RE; LePard, NE, 2000) |
| "For both of the two patients with pancreatic cancer, although they were responsive to the therapy, there was no prolongation of survival." | 1.31 | [Hepatic arterial infusion chemotherapy for unresectable liver metastasis of gastrointestinal cancers]. ( Hirakawa, K; Nishino, H; Ohira, M; Shimizu, S; Tamamori, Y; Tanaka, H; Yamada, N, 2000) |
| "A total of 18 patients (13: colon cancer, 5: gastric cancer) with multiple liver metastases (H3) underwent hepatic arterial infusion chemotherapy (HAI) using an implanted arterial port with portable syringe pumps in our outpatient clinic." | 1.31 | [Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases]. ( Fukunaga, M; Goda, F; Maeba, T; Maeta, H; Mihara, T; Mori, S; Ohkawa, M; Okada, H; Okano, K; Senda, S; Uchida, Y; Usuki, H; Wakabayashi, H, 2000) |
| "Mitomycin C is a powerful antineoplastic agent." | 1.31 | Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome. ( Catalano, C; Fabbian, F; Gianesini, C, 2002) |
| "Glutathione levels in human colon cancer cell line M7609 and its sensitivity to anticancer drugs were investigated in a complete medium RPMI-1640 (medium A) and an incomplete medium (medium B), which was prepared by removing glutathione and sulfur amino acids from medium A." | 1.30 | [Glutathione levels in human colon cancer cell line M7609 following culture in a low sulfur amino acid medium and its sensitivity to various anticancer drugs]. ( Hisai, H; Ikeda, S; Katahira, T; Kondo, H; Saito, T; Takahashi, Y; Takayama, T, 1997) |
| "Fifty-five colorectal cancer patients who had continuous intraportal chemotherapy between 1990 and 1993 (treated group) and 130 colorectal cancer patients who did not have portal chemotherapy between 1982 and 1993 (untreated group) were studied to clarify the effects of continuous intraportal chemotherapy on the prognosis." | 1.30 | [Continuous intraportal chemotherapy for prevention of metachronous hepatic metastasis in colorectal cancer]. ( Adachi, W; Amano, J; Kajikawa, S; Koide, N; Koike, S; Kuroda, T; Mihara, M; Nakata, S; Watanabe, H; Yazawa, K, 1998) |
| "Mitomycin C pretreatment also significantly increased the sensitivity of cancer cells to subsequent killing by the P-glycoprotein substrate doxorubicin, decreasing the ED50 by 5- to 10-fold." | 1.30 | Suppression of P-glycoprotein expression and multidrug resistance by DNA cross-linking agents. ( Blaxall, JR; Hamilton, JW; Ihnat, MA; La Ronde, N; Lariviere, JP; Pierre, KM; Turpie, BW; Warren, AJ, 1997) |
| "A panel of colon cancer cell lines with levels of MMC resistance from 2- to 15-fold compared to the parent line HT-29 was produced by repeated MMC exposure." | 1.30 | The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines. ( Greaves, B; Kang, Y; Lambert, PA; Perry, RR, 1998) |
| "One week after treatment complete necrosis of the tumour was observed in 8 of 10 rabbits that received MMC/Lipiodol (3 mg/ml) without severe adverse effects on the surrounding caecum." | 1.30 | Targeted cancer chemotherapy for VX2 tumour implanted in the colon with lipiodol as a carrier. ( Ishimaru, Y; Kitamura, N; Konno, T; Nagamitsu, A; Oda, T; Tabaru, K, 1998) |
| " To explain this tumor selectivity, the distribution of FK317 was investigated after dosing tumor-bearing mice with the 14C-labelled compound." | 1.30 | FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice. ( Fujiwara, T; Inami, M; Kawamura, I; Manda, T; Matsumoto, S; Naoe, Y; Nishigaki, F; Shimomura, K; Takagaki, S; Tsujimoto, S; Yamazaki, S, 1998) |
| "COLO201 colon cancer cells were stably transfected with human NQO1 cDNA that encodes NAD(P)H:quinone oxidoreductase (DT-diaphorase, DTD), and a clonal cell line with about 57-fold elevated DTD activity was obtained." | 1.30 | Regulatory network of mitomycin C action in human colon cancer cells. ( Hanaoka, H; Kirihara, Y; Kumazaki, T; Nishiyama, M; Okamoto, R; Okamura, T; Park, JS; Suzuki, K; Yamamoto, W; Yorishima, T, 1999) |
| "The role in colorectal cancer is less clear, although there are some reports that suggest a benefit." | 1.30 | Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer. ( Clingan, P; Horsell, KW; King, DW; Merten, S; Morris, DL, 1999) |
| "Six patients with gastric cancer and two patients with colon cancer underwent these procedures." | 1.29 | [Chemohyperthermic peritoneal perfusion and subtotal peritonectomy for peritonitis carcinomatosa in gastroenteric cancer]. ( Fujimura, T; Fujita, H; Fushida, S; Hirono, Y; Itoh, H; Kaji, M; Kinami, S; Nakagawara, H; Nakai, M; Yonemura, Y, 1995) |
| "10 patients with advanced colorectal cancer were treated with elevated doses of carmustine and mitomycin C." | 1.29 | Elevated doses of carmustine and mitomycin C, with lonidamine enhancement and autologous bone marrow transplantation in the treatment of advanced colorectal cancer: results from a pilot study. ( Codacci Pisanelli, G; Franchi, F; Giovagnorio, F; Gualdi, G; Guazzugli Bonaiuti, VP; Seminara, P, 1994) |
| "The MMC-sensitive HT-29 colon cancer cell line and its MMC-resistant subline, HT-29R13, were studied in vitro under aerobic conditions to help characterize the mechanisms associated with MMC resistance." | 1.29 | Biochemical characterization of a mitomycin C resistant colon cancer cell line variant. ( Greaves, B; Kang, Y; Perry, RR, 1993) |
| " The seven agents combined with CI-973 were mitomycin C, cyclophosphamide, doxorubicin, vinblastine, etoposide, ifosfamide, and methotrexate." | 1.29 | Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo. ( Elliott, WL; Howard, CT; Leopold, WR; Roberts, BJ, 1994) |
| " The appropriate dosage of six well-known antitumor drugs [mitomycin C (MMC), cyclophosphamide (CPA), nimustine hydrochloride 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), cis-platinum (II) diaminodichloride (CDDP), adriamycin (ADM) and 5-fluorouracil (5-FU)] in human tumor-bearing nude mice was determined based on the maximum tolerance dose of the drug." | 1.29 | A standardized method of using nude mice for the in vivo screening of antitumor drugs for human tumors. ( Abe, O; Hattori, T; Imaizumi, M; Kitano, M; Kondo, T; Taguchi, T; Wakui, A, 1993) |
| "Forty gastric cancer patients and 29 colorectal cancer patients were treated by subselective intraarterial infusion chemotherapy." | 1.29 | [Evaluation of subselective intraarterial infusion chemotherapy in far advanced gastric and colorectal cancer]. ( Fujimoto, T; Kitada, M; Murotani, M; Okumura, Y; Saito, M; Shibata, T; Takada, T; Takami, M; Tsukahara, Y; Watanabe, Y, 1993) |
| "Tegafur or UFT was administrated orally to patients with gastric or colorectal cancers after surgery for at least a year." | 1.29 | [Evaluation of long-term administration of oral anti-cancer agent]. ( Sakakibara, N; Watanabe, H, 1993) |
| "Peritoneal carcinomatosis has been regarded as a uniformly lethal clinical entity with no specific plan for management." | 1.29 | Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy. ( Sugarbaker, PH, 1996) |
| "The expression of MRP gene in gastric cancer cell lines varied from a low to a high level, but mdrl was not detected in any of these cell lines." | 1.29 | The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers. ( Cowan, KH; Fukuda, M; Ikeda, K; Kohno, S; Matsuo, I; Nakano, R; Narasaki, F; Oka, M; Soda, H; Takatani, H; Terashi, K; Tomonaga, M, 1996) |
| "Twelve colorectal cancer patients, including 9 with local recurrent cancer and 3 with remnant cancer after surgery, were treated with intraarterial chemotherapy." | 1.28 | [Intra-arterial chemotherapy of local recurrence and non-curative case of colorectal cancer]. ( Hashimoto, M; Hosoda, Y; Katai, H; Koh, J; Maeda, K; Murayama, Y; Sakai, S; Sano, M; Suzuki, K; Yamamoto, O, 1992) |
| " At a tolerable dosage level, bleomycin A6 exerted remarkable growth inhibition on human colon cancer HT-29 and cecum cancer Hce-8693 xenografts (approximately 90% inhibition)." | 1.28 | [Inhibitory effect of bleomycin A6 on human colon cancer xenografts in nude mice]. ( Deng, Y, 1990) |
| "once weekly for 20 wk to induce colon cancer." | 1.28 | Reduced growth rate of dimethylhydrazine-induced colon tumors in rats. ( Koike, T; Shibusawa, M; Tsunoda, A; Tsunoda, Y; Yasuda, N, 1992) |
| "A woman born in 1924 with colon cancer initially operated on approximately four years ago showed a second recurrence in the lung." | 1.28 | [A case of pulmonary metastasis from colon cancer responding completely to high-dose 5'-DFUR plus MMC combination chemotherapy]. ( Kawahara, T; Kikkawa, N; Kobayakawa, K; Tsuchiya, Y; Tsumura, I, 1991) |
| " Although the sensitivity of the serum-treated group to MMC was slightly higher than that of the untreated group, the dose-response curves of the tumor cells to MMC were similar to each other." | 1.28 | The influence of stromal cells on the MTT assay (II)--Study on the nude mouse system. ( Suto, A, 1991) |
| "A total of 22 patients (12 cases of gastric cancer, 6 of colon cancer, 2 of pancreas cancer, 1 of gall bladder cancer and 1 of biliary tract carcinoid) were treated according to the following schedule: both 10 mg of ADM (or MMC) and 0." | 1.28 | [Therapeutic effect of transarterial infusion immunochemotherapy for metastatic liver cancer]. ( Azuma, S; Furuta, T; Kawai, M; Kunieda, K; Miya, K; Saji, S; Sugiyama, Y; Takao, H; Tanemura, H; Umemoto, T, 1991) |
| "A new human colon cancer cell line (020588) has been derived by means of a combined in vitro matrix-in vivo xenograft technique." | 1.28 | A human colon cancer cell line established from collagen matrix cultures transplanted into nude mice. ( Agrez, MV; Chua, FK; Fagan, K; Ferguson, NW; Heath, JW, 1991) |
| "A case of iatrogenic sclerosing cholangitis secondary to hepatic intra-arterial 5-fluorouracil (5FU) and Mitomycin C (MMC) chemotherapy is described." | 1.28 | Serious chemical sclerosing cholangitis associated with hepatic arterial 5FU and MMC chemotherapy. ( Fukuzumi, S; Makuuchi, M; Moriya, Y; Terui, S, 1990) |
| " These results indicated that rIL 2 in combination with MMC might be effective against advanced carcinoma without causing severe toxicity when these drugs are used in an appropriate combination." | 1.28 | The effect of recombinant interleukin 2 in combination with mitomycin C on advanced cancer. ( Abe, R; Akiyoshi, T; Arinaga, S; Inoue, H; Karimine, N; Matsuoka, H; Nagamatsu, M; Nanbara, S; Takamuku, K; Watanabe, D, 1990) |
| "An adriamycin-resistant human colonic cancer cell line was characterized." | 1.28 | Increased mdr gene expression and decreased drug accumulation in a human colonic cancer cell line resistant to hydrophobic drug. ( Chao, CC; Cheng, PW; Lin-Chao, S; Ma, CM, 1990) |
| "Overall median survival was 352 days in colon cancer and 449 days in gastric cancer." | 1.28 | [A 5-FU, ADR, MMC combined hepatic arterial infusion therapy in non-resectable liver metastases from colon and gastric cancer]. ( Arai, Y; Endo, T; Kido, C; Miyake, Y; Sakamoto, K, 1989) |
| "Retreatment of patients with colon cancer and liver metastases by hepatic arterial infusion of fluorodeoxyuridine and mitomycin C can result in significant prolongation of survival in patients with response to this treatment." | 1.27 | Effective retreatment of patients with colorectal cancer and liver metastases. ( Chuang, VP; Mavligit, G; Patt, YZ; Peters, RE; Wallace, S, 1983) |
| "In patients with metastatic colorectal cancer involving only the liver, hepatic arterial FUDR alone and with the addition of mitomycin C provided excellent control of hepatic tumor." | 1.27 | Regional chemotherapy of colorectal cancer metastatic to the liver. ( Cozzi, E; Ensminger, W; Gyves, J; Niederhuber, JE; Thrall, J; Walker, S, 1984) |
| "In case of recurrent colorectal cancer, 17 cases of 27 patients has multiple liver metastasis." | 1.27 | [Treatment of recurrent gastrointestinal cancer]. ( Taguchi, T, 1983) |
| "Solid tumors are known to contain hypoxic cells and are relatively resistant to ionizing radiation and some chemotherapeutic agents." | 1.27 | Cytotoxicity of mitomycin C on clonogenic human carcinoma cells is not enhanced by hypoxia. ( Beaudry, JN; Ludwig, CU; Peng, YM; Salmon, SE, 1984) |
| "We studied 161 gastric cancer patients with P0, H(+) and 51 colorectal cancer patients with P0, H(+) from among cancer patients of the digestive organs and obtained the following conclusions." | 1.27 | [Basic and clinical studies on metastatic cancer--with special reference of multidisciplinary treatment of gastric and colorectal cancer patients with hepatic metastasis]. ( Hanaoka, A; Isono, K; Kimura, M; Koide, Y; Okuyama, K; Onoda, S; Ryu, M; Satoh, H; Tohnosu, N; Yamamoto, Y, 1983) |
| "To study the effectiveness of CDDP for hepatic cancer, intra-hepato-arterial administration of CDDP (0." | 1.27 | [Intra-hepato-arterial administration of cis-diammine-dichloroplatinum II (CDDP) for primary or metastatic hepatic cancer]. ( Hirooka, Y; Kanayama, H; Koga, S; Maeta, M; Murakami, A; Oda, M; Osaki, Y, 1984) |
| "We report 19 patients with metastatic colon cancer whose bulk disease was limited to the liver, but was not amenable to surgical resection." | 1.27 | Hepatic artery ligation and portal vein infusion for liver metastases from colon cancer. ( Courter, S; Guy, JF; Guy, JT; Laufman, LR; Nims, TA, 1984) |
| "Tow cases of gastric cancer were reported." | 1.27 | [2 cases of solitary metastasis to the large intestine from gastric carcinoma]. ( Hattori, T; Matsuki, K; Nakano, A; Niimi, K; Tomoda, S; Yoshinaka, K, 1984) |
| "The PR cases were 4 of stomach cancer and 2 of lung cancer, the former being all undifferentiated adenocarcinoma." | 1.27 | [Phase II study of KW 2083 [7-N-(p-hydroxyphenyl)-mitomycin C] in patients with various cancers]. ( Harashima, S; Kanko, T; Nakao, I; Nishi, I; Ohashi, Y; Saito, T; Yokoyama, T, 1984) |
| "Pseudomyxoma peritonei is an unusual malignancy arising from the goblet cells of the large bowel or appendix." | 1.27 | Malignant pseudomyxoma peritonei of colonic origin. Natural history and presentation of a curative approach to treatment. ( Kern, K; Lack, E; Sugarbaker, PH, 1987) |
| "The chemosensitivity of human colorectal cancer was studied in relation to the biological features of the tumor using a human tumor/nude mouse in-vivo system." | 1.27 | Biological features and chemosensitivity of human colorectal cancer xenografted in nude mice. ( Yamada, K, 1987) |
| "Twenty patients with colon cancer metastatic to the liver underwent successful hepatic resection and adjuvant perioperative therapy that included hepatic arterial mitomycin C and floxuridine (FUDR)." | 1.27 | Adjuvant perioperative hepatic arterial mitomycin C and floxuridine combined with surgical resection of metastatic colorectal cancer in the liver. ( Ames, FC; Boddie, AW; Charnsangavej, C; Claghorn, LJ; Cleary, KR; Mavligit, GM; McBride, CM; Patt, YZ, 1987) |
| "Forty-one patients with colorectal cancer, including ten patients with postoperative metastasis, were given A7-NCS." | 1.27 | Clinical application of monoclonal antibody-drug conjugates for immunotargeting chemotherapy of colorectal carcinoma. ( Hashimoto, Y; Honda, M; Kitamura, K; Kotanagi, H; Suzuyama, H; Takahashi, M; Takahashi, T; Yamaguchi, T; Yokota, T, 1988) |
| "Forty one patients with colorectal cancer including 10 patients with postoperative metastasis were given A7-NCS." | 1.27 | [Clinical application of monoclonal antibody-drug conjugates in colorectal carcinoma]. ( Hata, K; Kitamura, K; Noguchi, A; Sakita, M; Takahashi, T; Yamaguchi, T, 1988) |
| "Effect of this treatment on the pain could be evaluated in 16 patients." | 1.27 | Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin. ( Chuang, VP; Claghorn, L; Mavligit, G; Patt, YZ; Peters, RE; Wallace, S, 1985) |
| "The mitomycin C and BCNU were alternated monthly at the start of each FUDR cycle." | 1.27 | Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy. ( Cohen, AM; Higgins, J; Schaeffer, N, 1986) |
| "Sixty-six patients with advanced colorectal cancer were treated with 5-fluorouracil, Mitomycin C, and 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea." | 1.27 | The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced colorectal cancer. ( Chapman, J; Chinn, B; Demitrish, MM; Enochs, K; Garland, M; Groshko, G; Pederson, B; Rocchio, R; Vaughn, CB; Ward, D, 1986) |
| "When mitomycin C (MMC) was administered into the superior mesenteric vein 15 min after the inoculation of tumor cells, the number of metastatic foci in the liver was strongly inhibited; 81." | 1.27 | Liver metastasis of colon 26 cells implanted into the superior mesenteric vein in mice. ( Kitamura, M; Kosaki, G; Tominaga, T; Yoshida, Y, 1987) |
| "Since colorectal cancer tissues are resistant to various antitumor drugs, the chemosensitivity test of HCFU should aid in determining the effects of a particular drug for an individual patient." | 1.27 | Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil. ( Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K, 1988) |
| "Excisions of metastatic liver cancer were performed in 23 pts and 15 pts had nonresectable metastatic liver cancer." | 1.27 | [Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer]. ( Hojo, K; Moriya, Y; Sawada, T, 1988) |
| "Chemical cholecystitis has been recognized recently as a complication of hepatic artery infusion chemotherapy." | 1.27 | Hepatobiliary scintigraphy in patients receiving hepatic artery infusion chemotherapy. ( Dakhil, SR; Housholder, DF; Hynes, HE; Marymont, JV, 1985) |
| "Mitomycin C (MMC) was conjugated with the human colon cancer-specific monoclonal antibody, using a cyanogen bromide method." | 1.27 | Potent effects of the monoclonal antibody-mitomycin C conjugate on human colon cancers. ( Fukuda, K; Kotanagi, H; Koyama, K; Masuda, T; Ogata, N; Takahashi, M; Takahashi, T, 1987) |
| "Four out of five xenografts (three gastric cancer, one colon cancer) showed synergistic effects for the combination of MMC with alpha-interferon." | 1.27 | [Assessment of the combined effects of mitomycin C with alpha-interferon or gamma-interferon by the clonogenic assay technique]. ( Hattori, T; Hirabayshi, N; Niimoto, M; Nishiyama, M; Nosoh, Y; Ohkita, T; Toge, T; Yamaguchi, M; Yoshinaka, K, 1985) |
| "Five patients with colorectal cancer and unresectable synchronous liver metastases have survived for over five years at this writing." | 1.27 | Long-term survivors of colorectal cancer with unresectable hepatic metastases. ( Fujimoto, S; Higuchi, M; Kitsukawa, Y; Miyazaki, M; Okui, K, 1985) |
| "Metastatic colorectal cancer occurring in the pelvis was basically a vascular-deficient tumor." | 1.27 | Pelvic intra-arterial mitomycin C infusion in previously treated patients with metastatic, unresectable, pelvic colorectal cancer and angiographic determination of tumor vascularity. ( Park, HC; Tseng, MH, 1985) |
| "A 61-year-old man with double colon cancers and a solitary hepatic metastasis underwent right hemicolectomy and catheterization of the proper hepatic artery in April 1979." | 1.27 | [A long survival case of carcinoma of the colon with hepatic metastasis following intra-arterial infusion chemotherapy]. ( Itoh, J; Koyama, K; Masuda, T; Narisawa, T, 1985) |
| "Multimodality therapy for colorectal cancer is composed of surgery, chemotherapy and irradiation; and hyperthermia joins them recently." | 1.27 | [Multimodality therapy of colorectal cancer]. ( Fujimoto, S; Miyazaki, M; Okui, K, 1985) |
| "Though two gastric cancer xenografts exhibited synergistic effects in combination of gamma-interferon with Mitomycin C, antagonistic effects, which was not found in combination of alpha-interferon with Mitomycin C, were observed in one gastric cancer and one colon cancer xenografts." | 1.27 | In vitro chemosensitivity tests on human tumor xenografts by clonogenic assay: the combined use of mitomycin C with alpha-interferon or gamma-interferon. ( Hattori, T; Hirabayashi, N; Niimoto, M; Nosoh, Y; Ohkita, T; Toge, T; Yoshinaka, K, 1985) |
| "One case of each of ovarian cancer and gastric cancer showed minor response." | 1.27 | [A clinical trial of a new mitomycin C derivative, KW-2083 (7-N-(p-hydroxyphenyl)-mitomycin C)]. ( Takahashi, H; Takahashi, K; Wakui, A; Yokoyama, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 149 (39.01) | 18.7374 |
| 1990's | 137 (35.86) | 18.2507 |
| 2000's | 66 (17.28) | 29.6817 |
| 2010's | 23 (6.02) | 24.3611 |
| 2020's | 7 (1.83) | 2.80 |
| Authors | Studies |
|---|---|
| Kunz, KR | 1 |
| Iyengar, BS | 1 |
| Dorr, RT | 2 |
| Alberts, DS | 2 |
| Remers, WA | 1 |
| Islam, I | 1 |
| Skibo, EB | 1 |
| Sengupta, SK | 2 |
| Kogan, Y | 1 |
| Kelly, C | 1 |
| Szabo, J | 1 |
| Rosenbaum, DP | 1 |
| Sehgal, RK | 1 |
| Almassian, B | 1 |
| Blondin, J | 1 |
| Iwasa, K | 1 |
| Moriyasu, M | 1 |
| Yamori, T | 1 |
| Turuo, T | 1 |
| Lee, DU | 1 |
| Wiegrebe, W | 1 |
| Pawar, VU | 1 |
| Ghosh, S | 1 |
| Chopade, BA | 1 |
| Shinde, VS | 1 |
| Guo, X | 1 |
| Lin, Y | 1 |
| Shen, C | 1 |
| Li, Y | 1 |
| Xiang, F | 1 |
| Ruan, T | 1 |
| Zeng, X | 1 |
| Lv, J | 1 |
| Tao, K | 1 |
| Wu, C | 1 |
| Wintjens, AGWE | 1 |
| Liu, H | 1 |
| Fransen, PKH | 1 |
| Lenaerts, K | 1 |
| van Almen, GC | 1 |
| Gijbels, MJ | 1 |
| Hadfoune, M | 1 |
| Boonen, BTC | 1 |
| Lieuwes, NG | 1 |
| Biemans, R | 1 |
| Dubois, LJ | 1 |
| Dankers, PYW | 1 |
| de Hingh, IHJT | 1 |
| Bouvy, ND | 1 |
| Woeste, MR | 1 |
| Philips, P | 1 |
| Egger, ME | 1 |
| Scoggins, CR | 1 |
| McMasters, KM | 1 |
| Martin, RCG | 1 |
| Shelygin, YA | 1 |
| Sushkov, OI | 1 |
| Sukhina, MA | 1 |
| Saifutdinova, KR | 1 |
| Muratov, II | 1 |
| Shakhmatov, DG | 1 |
| Achkasov, SI | 1 |
| Arjona-Sanchez, A | 1 |
| Aziz, O | 1 |
| Passot, G | 1 |
| Salti, G | 1 |
| Esquivel, J | 1 |
| Van der Speeten, K | 1 |
| Piso, P | 1 |
| Nedelcut, DS | 1 |
| Sommariva, A | 1 |
| Yonemura, Y | 3 |
| Turaga, K | 1 |
| Selvasekar, CR | 1 |
| Rodriguez-Ortiz, L | 1 |
| Sanchez-Hidalgo, JM | 1 |
| Casado-Adam, A | 1 |
| Rufian-Peña, S | 1 |
| Briceño, J | 1 |
| Glehen, O | 1 |
| Ciniero, G | 1 |
| Elmenoufy, AH | 1 |
| Gentile, F | 1 |
| Weinfeld, M | 1 |
| Deriu, MA | 1 |
| West, FG | 1 |
| Tuszynski, JA | 1 |
| Dumontet, C | 1 |
| Cros-Perrial, E | 1 |
| Jordheim, LP | 1 |
| Su, LD | 1 |
| Peng, JM | 1 |
| Ge, YB | 1 |
| Vogl, TJ | 1 |
| Lahrsow, M | 1 |
| Albrecht, MH | 1 |
| Hammerstingl, R | 1 |
| Thompson, ZM | 1 |
| Gruber-Rouh, T | 1 |
| Schubert, J | 1 |
| Khosrawipour, V | 1 |
| Chaudhry, H | 1 |
| Arafkas, M | 1 |
| Knoefel, WT | 1 |
| Pigazzi, A | 1 |
| Khosrawipour, T | 1 |
| Votanopoulos, KI | 1 |
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| Jo, T | 1 |
| Weber-Stadelmann, W | 1 |
| Arizuka, S | 1 |
| Ashida, Y | 1 |
| Heim, S | 1 |
| Eckhardt, S | 1 |
| Yokoyama, M | 1 |
| Takahashi, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diagnostic Value of Diffusion-weighted Magnetic Resonance Imaging for Detection of Peritoneal Recurrence in Patients With High-risk Colorectal and Appendiceal Neoplasms : a Pilot Study[NCT05623787] | 30 participants (Anticipated) | Interventional | 2022-09-01 | Recruiting | |||
| Comparative Study on the Efficacy of Mitomycin and Lobaplatin in the Treatment of Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy[NCT04845490] | Phase 2 | 201 participants (Anticipated) | Interventional | 2022-09-01 | Not yet recruiting | ||
| A Pilot Study of AMP-224, a PD-1 Inhibitor, in Combination With Stereotactic Body Radiation Therapy (SBRT) in Patients With Metastatic Colorectal Cancer[NCT02298946] | Phase 1 | 17 participants (Actual) | Interventional | 2014-11-21 | Completed | ||
| Immunogenicity and Safety of Autologous Dendritic Cells in Patients With Breast Cancer Treated With Neoadjuvant Chemotherapy.[NCT03450044] | Phase 1/Phase 2 | 15 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Study of the Response to a Neoadjuvant Chemotherapy Based on the Antitumor Immune Response in Localized Breast Cancer[NCT01440413] | 40 participants (Anticipated) | Interventional | 2011-12-31 | Active, not recruiting | |||
| Phase I Trial of Romidepsin Given on Days One, Three, and Five in Patients With Thyroid and Other Advanced Cancers[NCT00048334] | Phase 1 | 28 participants (Actual) | Interventional | 2002-10-26 | Completed | ||
| Phase I Study of Topical Romidepsin (Depsipeptide) in Early Stage Cutaneous T-Cell Lymphoma[NCT01445340] | Phase 1 | 6 participants (Actual) | Interventional | 2007-04-21 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mandatory post treatment biopsies of the tumor were attempted on all patients. (NCT02298946)
Timeframe: Post treatment, day 29 +/- 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 6 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 0 |
Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT02298946)
Timeframe: Date treatment consent signed to date off study, approximately 24 months and 8 days
| Intervention | Participants (Count of Participants) |
|---|---|
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 6 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 9 |
Progression free survival is defined as the time interval from start of treatment to documented evidence of disease progression. Disease progression was evaluated by the Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 and is at least a 20% increase in the sum of the diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study). In addition to the relative increase of 20%, the sum must also demonstrate an absolute increase of at least 5mm. (Note: the appearance of one or more new lesions is also considered progressions). (NCT02298946)
Timeframe: Baseline to disease progression, an average of 2.6 months.
| Intervention | months (Median) |
|---|---|
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 1.7 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 2.7 |
"Objective response will be evaluated according to the revised Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 and is defined as Complete Response + Partial Response. Briefly, complete response (CR) is defined as the disappearance of all target lesions, and Partial Response is defined as at least 30% decrease in the sum of the diameters of the target lesions from baseline measurement." (NCT02298946)
Timeframe: Restaging was done every 8 weeks for an average of 2.6 months.
| Intervention | percentage of participants (Number) |
|---|---|
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 0 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 0 |
Overall survival is defined as the time from treatment start date until date of death or date last known alive. (NCT02298946)
Timeframe: Baseline to end of study, which is date of death. Average time participants were followed was 10.6 months.
| Intervention | months (Median) |
|---|---|
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 4.3 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 9.0 |
This outcome measure only represents the number of participants with metastatic colorectal cancer who had specimens collected for pre and post pharmacokinetic (PK) AMP-224 analyses. (NCT02298946)
Timeframe: Baseline and post infusion AMP-224 (e.g. 15 minutes after infusion ended)
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Pre AMP-224 | Post AMP-224 | |
| DL1 - CTX, SBRTx1 Day, & AMP-224 | 6 | 6 |
| DL2 - CTX, SBRTx3 Days, and AMP-224 | 9 | 9 |
14 reviews available for mitomycin and Colonic Neoplasms
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
Chemotherapy in alimentary tract malignomas.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carmustine; Colonic Neoplasms; Cytarabine; Doxor | 1981 |
Heterogeneity of human colon carcinoma.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Clone | 1984 |
Adjuvant postoperative therapy of gastrointestinal malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Combined | 1994 |
Adjuvant therapy for colon adenocarcinoma: current status of clinical investigation.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Chemotherapy, Adjuvant; | 1994 |
[The current status of postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colect | 1997 |
[DT-diaphorase].
Topics: Antibiotics, Antineoplastic; Aziridines; Colonic Neoplasms; Cytochrome Reductases; Cytochrome-B(5) R | 1997 |
Adjuvant therapy with oral fluoropyrimidines as main chemotherapeutic agents after curative resection for colorectal cancer: individual patient data meta-analysis of randomized trials.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 1999 |
[Is portal infusion chemotherapy uneffective for hepatic recurrence after resection for colorectal cancer?].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration | 1999 |
[Host factors that changes the distribution of immunotoxin].
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Doxorubicin; Humans; Immunotoxins; Mice; Mice, N | 1990 |
[Recent advanced studies on mitomycins, antitumor activity and mode of action].
Topics: Animals; Cell Line; Colonic Neoplasms; Humans; Leukemia P388; Mitomycin; Mitomycins; Neoplasms; Panc | 1987 |
Hepatic artery ligation or embolization and locoregional chemotherapy of liver metastases from colorectal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Emboli | 1988 |
Potentiation of antimetabolite action by alkylating agents.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brea | 1985 |
53 trials available for mitomycin and Colonic Neoplasms
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Routine second-look after surgical treatment of colonic peritoneal carcinomatosis.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemo | 2015 |
A phase I trial of thermal sensitization using induced oxidative stress in the context of HIPEC.
Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hum | 2013 |
[Cytoreductive surgery with intraperitoneal chemotherapy in patients with colon cancer and peritoneal carcinomatosis].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Combined | 2003 |
Cytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy for peritoneal carcinomatosis arising from colon adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Differe | 2003 |
Results of a randomized trial with or without 5-FU-based preoperative chemotherapy followed by postoperative chemotherapy in resected colon and rectal carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 2003 |
Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-flu
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2004 |
Phase II study of cisplatin and 5-fluorouracil (PF) and mitomycin C, vincristine, cisplatin and 5-fluorouracil (MVPF) in patients with metastatic large bowel cancer: an Eastern Cooperative Oncology Group study (EST 1285).
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Disease Progression; D | 2004 |
Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose Mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dexamethasone; Dose- | 2005 |
[Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Pr | 2005 |
Significance of histologic type of primary lesion and metastatic lymph nodes as a prognostic factor in stage III colon cancer.
Topics: Adenocarcinoma; Alkylating Agents; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic | 2006 |
Randomized trial of the efficacy of adjuvant chemotherapy for colon cancer with combination therapy incorporating the oral pyrimidine 1-hexylcarbamoyl-5-fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Com | 2006 |
Preliminary research on the evaluation of some prognostic factors in a randomized study of adjuvant immunochemotherapy in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Ne | 1984 |
[A prospective randomized clinical trial comparing intra-arterial chemotherapy alone and when combined with hyperthermia for metastatic liver cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1995 |
Five-year results of a randomized controlled trial of adjuvant chemotherapy for curatively resected colorectal carcinoma. The Colorectal Cancer Chemotherapy Study Group of Japan.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis | 1995 |
[Cooperative study of surgical adjuvant chemotherapy for colorectal cancer. Cooperative Study Group of Surgical Adjuvant Chemotherapy for Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1995 |
[The value of hepatic arterial infusion chemotherapy for liver metastases--discussion from viewpoints of prevention of hepatic death and QOL].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Fl | 1994 |
[A study of various complications in arterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Catheters, Indwelling; | 1994 |
[The efficacy of intra-arterial infusion chemotherapy in patients with non-resectable liver metastasis from colorectal cancer--a randomized study comparing FAM versus FEM].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Ad | 1993 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (third report): five-year results after surgery].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1993 |
[Cooperative Study of Surgical Adjuvant Chemotherapy for Colorectal Cancer (fourth report): five-year results after surgery].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1993 |
Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients.
Topics: Colonic Neoplasms; Fibroma; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Sti | 1996 |
Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemothe | 1996 |
[Intrahepatic arterial infusion chemotherapy for the colon cancer patients with liver metastases--a comparison of arterial embolization chemotherapy versus continuous arterial infusion chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Admi | 1996 |
[The importance of adjuvant chemotherapy in the treatment of colonic carcinoma: SAKK Study 40/93 (Swiss Work Group for Clinical Cancer Research)].
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites | 1997 |
Selective chemoembolization in the management of hepatic metastases in refractory colorectal carcinoma: a phase II trial.
Topics: Abdominal Pain; Adult; Aged; Alkaline Phosphatase; Angiography; Antimetabolites, Antineoplastic; Ant | 1997 |
Postsurgical sequential methotrexate, fluorouracil, and leucovorin for advanced colorectal carcinoma: a preliminary study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Dis | 1997 |
[Prospective controlled study on the usefulness of Carmofur as a postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Admi | 1997 |
[Evaluation of intermittent hepatic arterial infusion chemotherapy for multiple liver metastasis of colorectal cancer].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Femal | 1999 |
[Arterial infusion therapy with implantable port for inoperable hepatobiliary tumors].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neopla | 1999 |
Treatment of primary colon cancer with peritoneal carcinomatosis: comparison of concomitant vs. delayed management.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic N | 2000 |
[Clinical study on Shenqi Fuzheng injection combined with chemotherapy in treating malignant tumor of digestive tract].
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Colo | 1998 |
[Comparative study of UFT plus mitomycin C and UFT plus doxorubicin in adenocarcinoma. Hirosaki Cooperative Group of Cancer Chemotherapy].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Proto | 1992 |
[Clinical effect of postoperative adjuvant chemotherapy for advanced colorectal cancer--comparisons of between tegafur (FT) and UFT].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1991 |
[Concepts in the prevention and treatment of liver metastases of colorectal cancer by regional chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Colonic Ne | 1988 |
[Outcome of adjuvant mifurol chemotherapy in patients with resected colonic carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1989 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): a preliminary report. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal carcinoma (second study): 3-year survival after surgery of non-curatively resected patients. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; Drug A | 1989 |
[Randomized study of lentinan on patients with advanced gastric and colorectal cancer. Tohoku Lentinan Study Group].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration | 1986 |
[Prospective adjuvant chemotherapy, with mitomycin C plus long-term carmofur in colorectal cancer].
Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; D | 1986 |
[Adjuvant chemotherapy of colorectal cancer--results of prospective randomized trials].
Topics: Administration, Rectal; Adult; Aged; Colonic Neoplasms; Drug Administration Schedule; Female; Humans | 1986 |
[Cooperative study of surgical adjuvant chemotherapy of colorectal cancer (first report): Investigation of background factors and adverse effects. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorourac | 1987 |
Intraportal chemotherapy in colorectal carcinoma as an adjuvant modality.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; C | 1987 |
Mitomycin C plus carmofur (HCFU) adjuvant chemotherapy for noncuratively resected cases of colorectal carcinoma (interim report).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 1987 |
Superselective intra-arterial chemotherapy with mitomycin C in liver and gallbladder cancer.
Topics: Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Gallbladder Neoplasms; Humans; I | 1988 |
[Prospective adjuvant chemotherapy of mitomycin C plus HCFU for colorectal cancer (2d report)--6-year survival after surgery: Tokai Cooperative Study Group of Surgical Adjuvant Chemotherapy].
Topics: Adjuvants, Immunologic; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colect | 1988 |
[Clinical effect of postoperative adjuvant immunochemotherapy with the FT-207 suppository and PSK in colorectal cancer patients. Colorectal Cancer Chemotherapy Group in Hokuriku].
Topics: Administration, Oral; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Hu | 1988 |
[A cooperative study of surgical adjuvant chemotherapy of colorectal cancer (second report): 3-year survival rate. Cooperative Study Group of Surgical Adjuvant Chemotherapy of Colorectal Cancer in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Humans; Mitomycin; M | 1988 |
Pilot study on the regional treatment of colorectal liver metastases by intermittent arterial ischaemia with degradable starch microspheres and arterial and portal infusion with mitomycin C plus 5-fluorouracil--a clinical trial led by the Gastrointestinal
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neoplasms; Emboliz | 1988 |
Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; C | 1986 |
[Results of phase III study of lentinan].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colonic Neopl | 1985 |
[Studies on the effects of adjuvant chemotherapy on the survival period of patients with colorectal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th | 1985 |
The need for pilot studies and surgery-only controls in adjuvant therapy trials for large-bowel cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topi | 1985 |
316 other studies available for mitomycin and Colonic Neoplasms
| Article | Year |
|---|---|
Structure-activity relationships for mitomycin C and mitomycin A analogues.
Topics: Animals; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Female; Humans; Leukemi | 1991 |
Structure-activity studies of antitumor agents based on pyrrolo[1,2-a]benzimidazoles: new reductive alkylating DNA cleaving agents.
Topics: Alkylation; Antineoplastic Agents; Aziridines; Benzimidazoles; Colonic Neoplasms; DNA; Female; Free | 1991 |
New actinomycin D analogues as superior chemotherapeutic agents against primary and advanced colon tumors and colon xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Humans; Leukemia L1210; Leukemia P3 | 1988 |
Enantiomers of 7-(2,3-epoxypropoxy)actinomycin D as dual-action DNA-acting antitumor agents.
Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dactinomycin | 1988 |
In vitro cytotoxicity of the protoberberine-type alkaloids.
Topics: Animals; Antineoplastic Agents, Phytogenic; Berberine; Berberine Alkaloids; Brain Neoplasms; Breast | 2001 |
Design and synthesis of harzialactone analogues: promising anticancer agents.
Topics: 4-Butyrolactone; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Design; Drug Scree | 2010 |
Comparative Study of Short-Term Efficacy and Safety of Mitomycin versus Lobaplatin for Hyperthermic Intraperitoneal Chemotherapy after Radical Surgery in Colorectal Cancer with High-Risk Factors for Peritoneal Carcinomatosis: A Propensity Score Matching A
Topics: Colonic Neoplasms; Combined Modality Therapy; Humans; Hyperthermia, Induced; Hyperthermic Intraperit | 2023 |
Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal model.
Topics: Animals; Colonic Neoplasms; Colorectal Neoplasms; Cytostatic Agents; Hydrogels; Mitomycin; Peritonea | 2023 |
Optimal perfusion chemotherapy: A prospective comparison of mitomycin C and oxaliplatin for hyperthermic intraperitoneal chemotherapy in metastatic colon cancer.
Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Cytoreduction Surgical Procedur | 2020 |
[Effectiveness of intraperitoneal chemotherapy for t4 colon cancer].
Topics: AC133 Antigen; Antibiotics, Antineoplastic; Ascitic Fluid; CD24 Antigen; Cell Proliferation; Colonic | 2020 |
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for limited peritoneal metastasis. The PSOGI international collaborative registry.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Cy | 2021 |
Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair.
Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Computer S | 2021 |
Formyl peptide receptor 2 mediated chemotherapeutics drug resistance in colon cancer cells.
Topics: Adult; Aged; Carrier Proteins; Cell Line, Tumor; Cell Survival; Chemotactic Factors; Colonic Neoplas | 2018 |
Survival of patients with non-resectable, chemotherapy-resistant colorectal cancer liver metastases undergoing conventional lipiodol-based transarterial chemoembolization (cTACE) palliatively versus neoadjuvantly prior to percutaneous thermal ablation.
Topics: Ablation Techniques; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; | 2018 |
Comparing the cytotoxicity of taurolidine, mitomycin C, and oxaliplatin on the proliferation of in vitro colon carcinoma cells following pressurized intra-peritoneal aerosol chemotherapy (PIPAC).
Topics: Aerosols; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Colonic Neo | 2019 |
Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Appendic | 2013 |
The key role of calreticulin in immunomodulation induced by chemotherapeutic agents.
Topics: Animals; Antigens, Surface; Antineoplastic Agents; Apoptosis; Calreticulin; Camptothecin; Carcinoma, | 2015 |
Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.
Topics: Adenoviridae; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologou | 2014 |
Peritoneal carcinomatosis of colorectal cancer: novel clinical and molecular outcomes.
Topics: Adenocarcinoma; Adult; Aged; Body Mass Index; Chemotherapy, Cancer, Regional Perfusion; Colonic Neop | 2017 |
Management for Peritoneal Metastasis of Colonic Origin: Role of Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy: A Single Institution's Experience During Two Decades.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarke | 2017 |
Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: promotion of cytotoxic response to mitomycin C and fluorouracil.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Blotting, Western; Calcium; Calcium Si | 2009 |
The effects of adjuvant experimental radioimmunotherapy and hyperthermic intraperitoneal chemotherapy on intestinal and abdominal healing after cytoreductive surgery for peritoneal carcinomatosis in the rat.
Topics: Abdominal Wall; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Chemotherapy, Cancer, R | 2008 |
[Water mobility of diffusion MRI in prediction of response to chemoembolization in liver cancer].
Topics: Adult; Aged; Chemoembolization, Therapeutic; Cisplatin; Colonic Neoplasms; Diffusion Magnetic Resona | 2009 |
Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasm | 2010 |
MK-1775, a small molecule Wee1 inhibitor, enhances anti-tumor efficacy of various DNA-damaging agents, including 5-fluorouracil.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytog | 2010 |
CIAPIN1 confers multidrug resistance through up-regulation of MDR-1 and Bcl-L in LoVo/Adr cells and is independent of p53.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfami | 2011 |
Involvement of the aldo-keto reductase, AKR1B10, in mitomycin-c resistance through reactive oxygen species-dependent mechanisms.
Topics: Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Antibiotics, Antineoplastic; Caspase 3; Colonic | 2011 |
Intraoperative versus early postoperative intraperitoneal chemotherapy after cytoreduction for colorectal peritoneal carcinomatosis: an experimental study.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemotherapy, Adjuvant; Colonic | 2012 |
[Intraabdominal chemotherapy of prevailing forms of colon cancer].
Topics: Abdominal Cavity; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Fluo | 2011 |
Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: studies with human gastro-entero-pancreatic ectopic tumor models.
Topics: Animals; Antibiotics, Antineoplastic; Cholesterol; Colonic Neoplasms; Drug Carriers; Drug Stability; | 2012 |
DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.
Topics: Acid Ceramidase; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Ceramides; Colonic Neop | 2012 |
[Combined management of colon cancer local recurrences with using intraabdominal chemotherapy].
Topics: Abdominal Cavity; Antibiotics, Antineoplastic; Colonic Neoplasms; Disease Management; Humans; Mitomy | 2011 |
HIPEC in T4a colon cancer: a defendable treatment to improve oncologic outcome?
Topics: Adult; Aged; Aged, 80 and over; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Chemotherapy, C | 2012 |
New insight into hyperthermic intraperitoneal chemotherapy: induction of oxidative stress dramatically enhanced tumor killing in in vitro and in vivo models.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Chemotherapy, Cancer, Regional | 2012 |
[Evaluation of the efficacy and prognostic factors for colorectal liver metastases treated with transcatheter arterial chemoembolization].
Topics: Adult; Aged; Aged, 80 and over; Antigens, Tumor-Associated, Carbohydrate; Carcinoembryonic Antigen; | 2012 |
Mitomycin-C induced hemolytic uremic syndrome: a case report.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Colonic Neoplasms; Diagnosis, Differ | 2002 |
Influence of 1 and 25 Hz, 1.5 mT magnetic fields on antitumor drug potency in a human adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Division; Cell Survival; Cisplatin; Colonic N | 2002 |
The study of chemiluminescence in gastric and colonic carcinoma cell lines treated by anti-tumor drugs.
Topics: Antibiotics, Antineoplastic; Cell Cycle; Colonic Neoplasms; Humans; Luminescent Measurements; Mitomy | 2003 |
Therapy-related erythroleukemia caused by the administration of UFT and mitomycin C in a patient with colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, | 2003 |
[A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Combined Modalit | 2003 |
Total abdominal colectomy, pelvic peritonectomy, and end-ileostomy for the surgical palliation of mucinous peritoneal carcinomatosis from non-gynecologic cancer.
Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasm | 2003 |
EARLY RESULTS OF COMBINED RADIATION AND CHEMOTHERAPY IN TREATMENT OF MALIGNANT TUMORS.
Topics: Antineoplastic Agents; Colonic Neoplasms; Dactinomycin; Fluorouracil; Humans; Lung Neoplasms; Mitomy | 1963 |
STUDIES ON REGIONAL PERFUSION AND INTRA-ARTERIAL INFUSION FOR CANCER CHEMOTHERAPY.
Topics: Antineoplastic Agents; Breast Neoplasms; Celiac Artery; Chemotherapy, Cancer, Regional Perfusion; Co | 1964 |
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis.
Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Fluorouracil; Humans; Image Interpretation, Computer-A | 2003 |
Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: identification of responders incorporating the age factor.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoem | 2004 |
Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associ | 2004 |
[Mitomycin-induced hemolytic uremia syndrome].
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Do | 2004 |
Dietary induction of NQO1 increases the antitumour activity of mitomycin C in human colon tumours in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Bone Marrow; Colonic Neoplasms; Dicumarol; Diet Therapy; Dimet | 2004 |
hTERT antagonizes p53-induced apoptosis independently of telomerase activity.
Topics: Apoptosis; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA-Bind | 2005 |
Hemicolectomy with concomitant heated intraperitoneal chemotherapy: a case study.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Colectomy; Co | 2005 |
[What we can learn from a case of medical malpractice].
Topics: Antibiotics, Antineoplastic; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Combined Modality The | 2005 |
Transarterial chemoembolization with degradable starch microspheres, irinotecan, and mitomycin-C in patients with liver metastases.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineo | 2006 |
Influence of chemotherapeutic agents and cytokines on the expression of 5-fluorouracil-associated enzymes in human colon cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Cisplatin; | 2006 |
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Catalytic Domain; Cell Line, Tumor; Ce | 2006 |
Histological response of peritoneal carcinomatosis after hyperthermic intraperitoneal chemoperfusion (HIPEC) in experimental investigations.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Chemotherapy, Cancer, Regi | 2006 |
Influence of antitumor drugs on the expression of Fas system in SW480 colon cancer cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Cisplatin; Coculture Techniques; Colonic Neopl | 2006 |
[Effects of hyperthermic chemotherapy on gastrointestinal cancer cells in vitro].
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Cispl | 2006 |
Synergistic effects of valproic acid and mitomycin C in adenocarcinoma cell lines and fresh tumor cells of patients with colon cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; | 2006 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
Calreticulin exposure increases cancer immunogenicity.
Topics: Animals; Anthracyclines; Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Calreticulin; | 2007 |
p53 targets identified by protein expression profiling.
Topics: Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Electrophoresis, Gel, Two-Dimensional; Gene Expressi | 2007 |
Nitric oxide inhibits Shiga-toxin synthesis by enterohemorrhagic Escherichia coli.
Topics: Bacteriophage lambda; Cell Line, Tumor; Coculture Techniques; Colonic Neoplasms; Epithelial Cells; E | 2007 |
A comparison between radioimmunotherapy and hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal carcinomatosis of colonic origin in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Body Weight; Colonic Neoplasms; Combin | 2007 |
The early response to DNA damage can lead to activation of alternative splicing activity resulting in CD44 splice pattern changes.
Topics: Alternative Splicing; Antibiotics, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Colonic Neoplas | 2007 |
UFT/leucovorin and mitomycin C as salvage treatment in patients with advanced colorectal cancer - a retrospective analysis.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colonic Neo | 2007 |
Hyperthermic intraperitoneal chemoperfusion is an option for treatment of peritoneal carcinomatosis in children.
Topics: Antibiotics, Antineoplastic; Carcinoma, Signet Ring Cell; Chemotherapy, Cancer, Regional Perfusion; | 2007 |
Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Biological Transport; Biomarkers; Cell Line, Tumor; Cell Nucleus | 2008 |
Hepatic artery infusion with 5-fluorouracil and mitomycin-C in metastatic colorectal carcinoma phase II study.
Topics: Adult; Aged; Catheterization; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; | 1982 |
Effective retreatment of patients with colorectal cancer and liver metastases.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Colonic Neoplasms; Drug Resistan | 1983 |
Regional chemotherapy of colorectal cancer metastatic to the liver.
Topics: Antineoplastic Agents; Catheters, Indwelling; Colonic Neoplasms; Drug Evaluation; Female; Floxuridin | 1984 |
[Chemotherapy of gastrointestinal cancer in the advanced stage with a combination of 5-fluorouracil, adriamycin, mitomycin C (FAM). A non-controlled study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Ev | 1984 |
[Chemotherapy of gastrointestinal cancer in elderly patients--evaluation of combination therapy with mitomycin C and 5-fluorouracil].
Topics: Aged; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Colonic Neoplasms; Drug Synergism; Dru | 1983 |
Hemolytic-uremic syndrome in a patient receiving mitomycin C and 5-fluorouracil.
Topics: Adenocarcinoma, Mucinous; Aged; Colonic Neoplasms; Fluorouracil; Hemolytic-Uremic Syndrome; Humans; | 1983 |
Enhancement of the cytocidal effect of mitomycin C by means of simultaneous administration of prostaglandin E1.
Topics: Alprostadil; Animals; Colonic Neoplasms; Drug Synergism; Humans; Injections, Intra-Arterial; Injecti | 1983 |
Mechanism of increased susceptibility to 4-nitroquinoline-1-oxide in cultured skin fibroblasts from patients with familial polyposis coli.
Topics: 4-Nitroquinoline-1-oxide; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Colonic | 1983 |
Phase II trial of combination chemotherapy of colonic cancer with 5-fluorouracil, mitomycin C, and hexamethylmelamine.
Topics: Altretamine; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Drug Eval | 1983 |
Response of a human colon adenocarcinoma (DLD-1) to X irradiation and mitomycin C in vivo.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Humans; Mice; Mice, Nude; M | 1983 |
[A study on postoperative long-term continuous immuno-chemotherapy with PSK and 5-FUDS for advanced gastric and colo-rectal cancers].
Topics: Aged; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Human | 1983 |
[Intra-arterial infusion chemotherapy for metastatic hepatic tumor of colo-rectal cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil | 1983 |
[Treatment of recurrent gastrointestinal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Humans; Infusions, I | 1983 |
Combination of dacarbazine, mitomycin C, 5-fluorouracil and vincristine in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dacarbazine; Female; | 1983 |
Increased sensitivity of cultured fibroblasts from colon cancer-prone rats to cytotoxicity of carcinogens and to viral transformation: a comparison with fibroblasts from patients with adenomatosis coli.
Topics: 4-Nitroquinoline-1-oxide; Adenoma; Animals; Carcinogens; Cell Division; Cell Survival; Cell Transfor | 1983 |
Cytotoxicity of mitomycin C on clonogenic human carcinoma cells is not enhanced by hypoxia.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Colonic Neoplasms; Humans; Mice; Mitomycin; Mitomyc | 1984 |
Treatment of metastatic colorectal carcinoma with 5-FU, mitomycin, vincristine, and methotrexate.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Fem | 1984 |
[Basic and clinical studies on metastatic cancer--with special reference of multidisciplinary treatment of gastric and colorectal cancer patients with hepatic metastasis].
Topics: Colonic Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Ar | 1983 |
[Constant intra-aortic infusion chemotherapy for advanced abdominal cancer--a technic and the effect in patients with peritoneal metastases].
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Coloni | 1984 |
[Intra-hepato-arterial administration of cis-diammine-dichloroplatinum II (CDDP) for primary or metastatic hepatic cancer].
Topics: Adult; Aged; Carcinoembryonic Antigen; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; F | 1984 |
[Intraabdominal administration of MMC adsorbed on activated carbon for management of carcinomatous peritonitis].
Topics: Abdomen; Carbon; Colonic Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Middle Aged; Mitomyc | 1984 |
Effects of mitomycin on human colon carcinoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Colonic Neoplasms; DNA Replication; | 1984 |
Antitumor activity and toxicity in animals of RR-150 (7-cysteaminomitosane), a new mitomycin derivative.
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistan | 1984 |
Mitomycin C resistance in a human colon carcinoma cell line associated with cell surface protein alterations.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Membrane; Cell Survival; Colonic Neoplasms; Dr | 1984 |
Regional intra-arterial mitomycin C infusion in previously treated patients with metastatic colorectal cancer and concomitant measurement of serum drug level.
Topics: Adenocarcinoma; Aged; Bone Marrow; Colonic Neoplasms; Female; Humans; Infusions, Intra-Arterial; Mal | 1984 |
[A clinicopathological study on hematogenous recurrence of colo-rectal cancer--with special reference to prediction and prevention of the recurrence].
Topics: Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Follow-Up Studies; Humans; Live | 1984 |
Hepatic artery ligation and portal vein infusion for liver metastases from colon cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Hepat | 1984 |
[2 cases of solitary metastasis to the large intestine from gastric carcinoma].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; | 1984 |
[Phase I-II study of 7-N-(P-hydroxyphenyl)-mitomycin C (KW2083, M83)].
Topics: Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Hum | 1984 |
[Phase II study of KW 2083 [7-N-(p-hydroxyphenyl)-mitomycin C] in patients with various cancers].
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Anorexia; Antibiotics, Antineoplastic; Aspartate Amin | 1984 |
Phase I study of 7-N-(p-hydroxyphenyl)-mitomycin C.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Humans; L | 1984 |
Phase II study of hepatic artery infusion with 5-fluorouracil, adriamycin, and mitomycin C (FAM) in liver metastases from colorectal carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorouracil; | 1984 |
[Effect of 7-N-(P-hydroxyphenyl)-mitomycin C (KW-2083) against pleuritis carcinomatosa].
Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antineoplastic Agents; Colonic Neoplasms; Female; Fever; Huma | 1984 |
Effectiveness of postoperative adjuvant therapy with cytotoxic chemotherapy (cytosine arabinoside, mitomycin C, 5-fluorouracil) or immunotherapy (neuraminidase-modified allogeneic cells) in the prevention of recurrence of Duke's B and C colon cancer.
Topics: Aged; Colonic Neoplasms; Cytarabine; Female; Fluorouracil; Humans; Immunotherapy; Male; Middle Aged; | 1981 |
Efficacy of dacarbazine imidazole carboxamide and mitomycin C combination therapy in patients with adenocarcinoma of the colon refractory to 5-fluorouracil therapy.
Topics: Adenocarcinoma; Colonic Neoplasms; Dacarbazine; Drug Resistance; Drug Therapy, Combination; Female; | 1981 |
Chemotherapy of carcinomas of the digestive tract.
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Esop | 1982 |
Intrahepatic artery 5-fluorouracil and mitomycin-C in previously untreated patients with hepatic metastases from colorectal carcinoma.
Topics: Adult; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Mitomyci | 1982 |
Baseline and mitomycin-C-induced sister chromatic exchanges ina melanoma and a colon tumor cell line.
Topics: Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Colonic Neoplasms; Crossing Over, Ge | 1982 |
Effects of selected compounds on the McCall rat colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azaserine; Colonic Neoplasms; Drug Therapy, Combinat | 1982 |
[Immunochemotherapy for colorectal cancer patients with levamisole].
Topics: Colonic Neoplasms; Drug Therapy, Combination; Humans; Immunity, Cellular; Levamisole; Lymphocyte Act | 1982 |
[Effect of mitomycin C on human gastric and colon carcinomas serially transplanted to nude mice--with special reference to the start of drug administration].
Topics: Animals; Cell Division; Colonic Neoplasms; Humans; Mice; Mice, Nude; Mitomycin; Mitomycins; Neoplasm | 1982 |
Hemostatic abnormalities and increased vascular endothelial cell markers in patients with red cell fragmentation syndrome induced by mitomycin C.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Cytokines; Disseminated Intravascular | 1995 |
Isolation and characterization of a mitomycin C-resistant variant of human colon carcinoma HT-29 cells.
Topics: Aerobiosis; Alkylation; Biotransformation; Cell Survival; Colonic Neoplasms; Dicumarol; DNA, Neoplas | 1993 |
Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, and mitomycin C on the growth and liver metastasis of human colon cancer.
Topics: Animals; Antibiotics, Antineoplastic; Body Weight; Cell Division; Colonic Neoplasms; Cyclohexanes; H | 1995 |
Curative treatments of murine Colon26 solid tumors by immunochemotherapy with G-CSF and OK-432.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Col | 1995 |
Cancer recurrence following laparoscopic colectomy. Report of two patients treated with heated intraperitoneal chemotherapy.
Topics: Adenocarcinoma; Colectomy; Colonic Neoplasms; Fluorouracil; Humans; Infusions, Parenteral; Laparosco | 1995 |
[Chemohyperthermic peritoneal perfusion and subtotal peritonectomy for peritonitis carcinomatosa in gastroenteric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Combined | 1995 |
Anti-tumour activity of photodynamic therapy in combination with mitomycin C in nude mice with human colon adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Death; Colonic Neoplasms; Combined Modality Therapy; Drug | 1995 |
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carc | 1995 |
[Home therapy approach in cancer patients-chemotherapy (case 2-1)].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorourac | 1994 |
NAD(P)H:quinone oxidoreductase expression and mitomycin C resistance developed by human colon cancer HCT 116 cells.
Topics: Base Sequence; Blotting, Western; Colonic Neoplasms; DNA, Complementary; DNA, Neoplasm; Drug Resista | 1995 |
Elevated doses of carmustine and mitomycin C, with lonidamine enhancement and autologous bone marrow transplantation in the treatment of advanced colorectal cancer: results from a pilot study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplant | 1994 |
In vitro effect of lonidamine on the cytotoxicity of mitomycin C and BCNU in human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Cell Cycle; Cell Survival; Colonic Neoplasms; Dos | 1994 |
Biochemical characterization of a mitomycin C resistant colon cancer cell line variant.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carrier Proteins; Coloni | 1993 |
Cytotoxic activity of 7-N-(2-((2-(-gamma-L-glutamylamino)- ethyl)dithio)ethyl)-mitomycin C and metabolites in cell lines with different resistance patterns.
Topics: Animals; Colonic Neoplasms; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Kinet | 1994 |
Treatment of patients with irresectable liver metastases from colorectal cancer by chemo-occlusion with degradable starch microspheres.
Topics: Adult; Aged; Chemoembolization, Therapeutic; Colonic Neoplasms; Female; Fluorouracil; Humans; Liver | 1994 |
Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2-)](2- methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Colonic Neoplasms; Cyclophosph | 1994 |
[Antitumor activity of LY 188011, a new deoxycytidine analog, against human cancers xenografted into nude mice].
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Colonic Neoplasms; Deoxycytidine; Drug Admini | 1994 |
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
Topics: Buthionine Sulfoximine; Colonic Neoplasms; Cysteine; Cytochrome P-450 Enzyme System; DNA, Neoplasm; | 1994 |
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chromobacterium; Colonic Neoplasms; Dep | 1994 |
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chromobacterium; Colonic Neoplasms; Dep | 1994 |
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chromobacterium; Colonic Neoplasms; Dep | 1994 |
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Chromobacterium; Colonic Neoplasms; Dep | 1994 |
Encapsulation of mitomycin C in albumin microspheres markedly alters pharmacokinetics, drug quinone reduction in tumour tissue and antitumour activity. Implications for the drugs' in vivo mechanism of action.
Topics: Adenocarcinoma; Albumins; Animals; Antineoplastic Agents; Biotransformation; Colonic Neoplasms; Drug | 1994 |
Morphologic analysis of three-dimensional tumors developed in fibrin matrix and agar culture system.
Topics: Adenocarcinoma; Agar; Animals; Cell Division; Cell Hypoxia; Colonic Neoplasms; Culture Techniques; E | 1993 |
Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity.
Topics: Aerobiosis; Antineoplastic Agents; Aziridines; Cell Hypoxia; Colonic Neoplasms; Dose-Response Relati | 1994 |
Enzymatic and pH modulation of mitomycin C-induced DNA damage in mitomycin C-resistant HCT 116 human colon cancer cells.
Topics: Biotransformation; Cell Death; Chemical Fractionation; Chromatography, Thin Layer; Colonic Neoplasms | 1993 |
A standardized method of using nude mice for the in vivo screening of antitumor drugs for human tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; Doxoru | 1993 |
Development and initial characterization of a mitomycin C-resistant colon cancer cell line variant.
Topics: Cell Cycle; Cell Division; Colonic Neoplasms; Drug Resistance; Humans; Mitomycin; Tumor Cells, Cultu | 1993 |
[Clinical study on the effect of continuous transarterial infusion chemotherapy of CDDP for metastatic liver tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Admi | 1993 |
[Evaluation of subselective intraarterial infusion chemotherapy in far advanced gastric and colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil; Humans; Inf | 1993 |
[Combination therapy of high dose doxifluridine (5'-DFUR)+mitomycin C (MMC) for advanced or recurrent colorectal cancer. Joint Research Group in the Osaka Area for Combination Therapy of 5'-DFUR with Other Drugs].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms | 1993 |
[Experimental and clinical study in vitro chemosensitivity test for succinate dehydrogenase inhibition test].
Topics: Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neopla | 1993 |
[Evaluation of long-term administration of oral anti-cancer agent].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Coloni | 1993 |
Potentiation of photodynamic therapy by mitomycin C in cultured human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Survival; Colonic Neoplasms; Dihematoporphyrin Ether; Dose-Response Relationshi | 1993 |
Alternative splicing and differential expression of DT-diaphorase transcripts in human colon tumors and in peripheral mononuclear cells in response to mitomycin C treatment.
Topics: Alternative Splicing; Antibiotics, Antineoplastic; Base Sequence; Carcinoma, Hepatocellular; Cell Li | 1996 |
Quinone-induced apoptosis in human colon adenocarcinoma cells via DT-diaphorase mediated bioactivation.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Aziridines; Benzoquinones; Colonic Neoplasms; Elec | 1996 |
DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
Topics: Antibiotics, Antineoplastic; Base Sequence; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Cytoc | 1996 |
[Prolongation of survival and antitumor activity of antitumor drugs in murine cancer cachexia model].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cachexia; Colonic Neoplasms; Dinoprostone; | 1996 |
[A case of effective chemotherapy by combination of 5'-DFUR and MMC for recurrent colon cancer with multiple liver metastasis].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Colonic Neoplasms; Drug A | 1996 |
Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Mice; Mice, Inbred Strains; Mitochondria; Mitomycin; Mol | 1996 |
[Studies on the in vivo and in vitro chemosensitivity tests using human tumor xenografts].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, An | 1995 |
Effect of acute and chronic intermittent hypoxia on DNA topoisomerase II alpha expression and mitomycin C-induced DNA damage and cytotoxicity in human colon cancer cells.
Topics: Colonic Neoplasms; DNA; DNA Damage; Dose-Response Relationship, Drug; Humans; Hypoxia; Isomerases; M | 1996 |
Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light.
Topics: Amino Acid Sequence; Animals; Antibodies; Antineoplastic Agents; CCAAT-Enhancer-Binding Proteins; Ce | 1996 |
Treatment of peritoneal carcinomatosis from colon or appendiceal cancer with induction intraperitoneal chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Appendiceal Neoplasms; Colonic Neoplasms; Female; Fluorouracil; | 1996 |
[Chemohyperthermic peritoneal perfusion and high-dose chemotherapy followed by peripheral blood stem cell transplantation in advanced colon cancer--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Colonic Neoplasms; Combined | 1996 |
The NAD(P)H:quinone oxidoreductase locus in human colon carcinoma HCT 116 cells resistant to mitomycin C.
Topics: Antibiotics, Antineoplastic; Chromosome Aberrations; Colonic Neoplasms; Down-Regulation; Drug Resist | 1996 |
The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers.
Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Etoposide; Genes, MD | 1996 |
[Glutathione levels in human colon cancer cell line M7609 following culture in a low sulfur amino acid medium and its sensitivity to various anticancer drugs].
Topics: Amino Acids, Sulfur; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Culture Media; Doxorubicin | 1997 |
Differential effects of EGF and amphiregulin on adhesion molecule expression and migration of colon carcinoma cells.
Topics: Adenocarcinoma; Amphiregulin; Androstadienes; Antigens, CD; Cadherins; Cell Adhesion; Cell Adhesion | 1997 |
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells.
Topics: Amphiregulin; Antineoplastic Agents; Cell Division; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Dox | 1997 |
[Evaluation of hepatic resection and hepatic arterial infusion chemotherapy for multiple liver metastases from colon cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 1997 |
Cutaneous metastasis as a complication of hepatic intra-arterial chemotherapy.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorourac | 1997 |
A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance.
Topics: Antibiotics, Antineoplastic; Antibodies; Biomarkers, Tumor; Carcinoma; Chemotherapy, Adjuvant; Chi-S | 1998 |
[Continuous intraportal chemotherapy for prevention of metachronous hepatic metastasis in colorectal cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration Schedul | 1998 |
Suppression of P-glycoprotein expression and multidrug resistance by DNA cross-linking agents.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, | 1997 |
Clinical applications of the histoculture drug response assay.
Topics: Antineoplastic Agents; Cell Culture Techniques; Chemotherapy, Adjuvant; Colonic Neoplasms; Colorecta | 1995 |
Pharmacological determinants of the antitumour activity of mitomycin C.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Biotransformation; Colonic Neoplasms; Metaboli | 1998 |
The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines.
Topics: Aerobiosis; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Ce | 1998 |
Targeted cancer chemotherapy for VX2 tumour implanted in the colon with lipiodol as a carrier.
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Carriers; Female; Infusions, Intra-Art | 1998 |
STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; | 1999 |
Anti-cachectic effect of FK317, a novel anti-cancer agent, in colon26 and LX-1 models in mice.
Topics: Adenocarcinoma; Adipose Tissue; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Blood G | 1998 |
FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biotransformation; Body Weight; Carcinoma, Large Cel | 1998 |
Regulatory network of mitomycin C action in human colon cancer cells.
Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; DNA, Complementary; Drug Screening Assays, Antitumor | 1999 |
Peritonectomy and intraperitoneal chemotherapy in appendiceal and colorectal cancer.
Topics: Abscess; Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; | 1999 |
Sensitization of resting T cells to autologous natural-killer-cell-mediated lysis by phytohemagglutinin.
Topics: Adenocarcinoma; Colonic Neoplasms; Concanavalin A; Cycloheximide; Cytotoxicity, Immunologic; Dactino | 1999 |
Interaction between gemcitabine and mitomycin-C in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Deoxycytidine; Drug Synergism; Ge | 2000 |
In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogeni | 2000 |
Antitumor effect of oxycellulose as a hemostatic during operation.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Erythrocytes; Etopo | 1998 |
Multidrug resistance increment in a human colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colc | 2000 |
Cost-effectiveness of hepatic arterial chemoembolization for colorectal liver metastases refractory to systemic chemotherapy.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benchmarking; C | 2000 |
Effects of mitomycin C on the oxygenation and radiosensitivity of murine and human tumours in mice.
Topics: Animals; Apoptosis; Cervix Uteri; Colon; Colonic Neoplasms; Disease Models, Animal; Female; Humans; | 2000 |
Tumor biology: use of tiled images in conjunction with measurements of cellular proliferation and death in response to drug treatments.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycl | 2000 |
Establishment of an isogenic human colon tumor model for NQO1 gene expression: application to investigate the role of DT-diaphorase in bioreductive drug activation in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Disease Models, Animal; Gene Expression; HT | 2000 |
[Hepatic arterial infusion chemotherapy for unresectable liver metastasis of gastrointestinal cancers].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Fluorouracil; Hepati | 2000 |
[Repetitive chemo-embolization with degradable starch microspheres (DSM) to each left and replaced right hepatic artery in a patient with multiple liver metastases of colon cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Colonic Neoplasms; E | 2000 |
Bax induction activates apoptotic cascade via mitochondrial cytochrome c release and Bax overexpression enhances apoptosis induced by chemotherapeutic agents in DLD-1 colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cisplatin; Coloni | 2000 |
Lanreotide-induced modulation of 5-fluorouracil or mitomycin C cytotoxicity in human colon cancer cell lines: a preclinical study.
Topics: Antineoplastic Agents; Cell Cycle; Cell Survival; Colonic Neoplasms; Drug Interactions; Drug Screeni | 2000 |
[Outcomes of home anti-cancer chemotherapy--estimation of hepatic arterial infusion chemotherapy for patients with multiple liver metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Fluorouracil; He | 2000 |
[Long-term survival of a patient with postoperative liver metastasis of stage IVa gallbladder cancer responding to hepatic arterial infusion chemotherapy].
Topics: Adenocarcinoma; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C | 2001 |
P-glycoprotein, glutathione and glutathione S-transferase increase in a colon carcinoma cell line by colchicine.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colc | 2000 |
Effect of combination therapy with matrix metalloproteinase inhibitor MMI-166 and mitomycin C on the growth and liver metastasis of human colon cancer.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; C | 2001 |
Deoxycholic acid stimulates migration in colon cancer cells.
Topics: Caco-2 Cells; Cell Division; Cell Movement; Colonic Neoplasms; Deoxycholic Acid; Dose-Response Relat | 2001 |
[Basic study on the sensitivity test for inhibiting fibroblast proliferation (II)].
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; | 2001 |
[Efficacy of postoperative adjuvant chemotherapy for colorectal cancer].
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Colonic | 2002 |
Expression of the prodrug-activating enzyme DT-diaphorase via Ad5 delivery to human colon carcinoma cells in vitro.
Topics: Adenoviridae; Antibiotics, Antineoplastic; beta-Galactosidase; Blotting, Western; Cell Division; Col | 2002 |
Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome.
Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; Erythropoietin; Female; Hemolytic-Uremic Syndrome; H | 2002 |
Collaborative validation study of the in vivo micronucleus test using mouse colonic epithelial cells.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Epitheli | 2002 |
Role of lipophilicity in the in vitro antitumour activity of a series of new mitosene compounds.
Topics: Animals; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Leukemia L1210; Membrane | 1992 |
Cytotoxicity and cytokinetic effects of mitomycin C and/or photochemotherapy in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Cell Cycle; Cell Survival; Colonic Neoplasms; Flow Cytometry; Humans; Mitomycin; Pho | 1992 |
The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells.
Topics: 2,6-Dichloroindophenol; Carbon Radioisotopes; Cell Extracts; Cell Size; Cell Survival; Colonic Neopl | 1992 |
Effect of treatment duration and glutathione depletion on mitomycin C cytotoxicity in vitro.
Topics: Buthionine Sulfoximine; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Glutathi | 1992 |
Correlation of eosinophilia with clinical response in patients with advanced carcinoma treated with low-dose recombinant interleukin-2 and mitomycin C.
Topics: Aged; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eosinophilia; | 1992 |
Myeloprotective activity of deoxyspergualin: influence on splenic colony-forming cell injury and antitumor activity of mitomycin C in mice.
Topics: Adenocarcinoma; Animals; Blood Cells; Bone Marrow; Bone Marrow Cells; Colonic Neoplasms; Dose-Respon | 1992 |
[Significance of antitumor effects and immunological response on endogenously induced LAK therapy for primary or metastatic liver tumor].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Administration | 1992 |
[Intra-arterial chemotherapy of local recurrence and non-curative case of colorectal cancer].
Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; Doxorubicin; Humans; Infusions, Intra-Arterial; Mitomycin | 1992 |
Effect of mitomycin C on the uptake of photofrin II in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Cell Cycle; Cell Division; Cell Membrane Permeability; Cell Survival; Colonic Neopla | 1992 |
The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins.
Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Cell Hypoxia; Colonic Neoplasms; | 1992 |
[Indication for chemoembolization of liver tumors. An interdisciplinary concept and initial results].
Topics: Adult; Chemoembolization, Therapeutic; Colonic Neoplasms; Female; Fluorouracil; Germany, West; Human | 1992 |
[Experimental chemotherapy of peritoneal carcinomatosis of colonic origin in rats].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Disease Models, Anim | 1992 |
The effect of angiotensin II on tumor blood flow and the delivery of microparticulate cytotoxic drugs.
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Colonic Neoplasms; D | 1992 |
Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
Topics: Antineoplastic Agents; Cell Line; Chromatography, High Pressure Liquid; Colonic Neoplasms; Colony-Fo | 1990 |
The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9.
Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Carcinoma 256, Walker; Colonic Neopla | 1991 |
[Inhibitory effect of bleomycin A6 on human colon cancer xenografts in nude mice].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cecal Neoplasms; Colonic Neoplasms; Female; Fluorouracil; | 1990 |
Reduced growth rate of dimethylhydrazine-induced colon tumors in rats.
Topics: Animals; Body Weight; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Eflornithine; Male; Mito | 1992 |
NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
Topics: Actins; Base Sequence; Colonic Neoplasms; DNA, Neoplasm; Gene Expression Regulation, Enzymologic; Ge | 1992 |
Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix.
Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Collagen; Colonic Neoplasms; Culture Media; Doxoru | 1992 |
Bile salt/acid induction of DNA damage in bacterial and mammalian cells: implications for colon cancer.
Topics: Animals; Bile Acids and Salts; CHO Cells; Colonic Neoplasms; Cricetinae; DNA; DNA Damage; DNA Repair | 1991 |
[A case of pulmonary metastasis from colon cancer responding completely to high-dose 5'-DFUR plus MMC combination chemotherapy].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic | 1991 |
Combination effect of recombinant human interleukin 1 alpha with antitumor drugs on syngeneic tumors in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Col | 1991 |
[Growth chamber assay, a novel chemosensitivity test which eliminates normal stromal cells].
Topics: Animals; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitum | 1991 |
Establishment of drug resistance in human gastric and colon carcinoma xenograft lines.
Topics: Animals; Blotting, Northern; Cell Line; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Resistance; | 1991 |
Effectiveness of isolated liver perfusion with mitomycin C in the treatment of liver tumours of rat colorectal cancer.
Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Cell Line; Colonic Neoplasms; DNA, Neopla | 1991 |
The influence of stromal cells on the MTT assay (II)--Study on the nude mouse system.
Topics: Animals; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Mitomycin; M | 1991 |
[Prevention of peritoneal dissemination after colorectal surgery--significance of MMC administration in abdominal cavity].
Topics: Ascitic Fluid; Colon; Colonic Neoplasms; Humans; Infusions, Parenteral; Mitomycin; Mitomycins; Perit | 1991 |
[The efficacy of intra-arterial infusion chemotherapy in patients with metastatic liver tumors].
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Catheters, Indwelling; Colonic Neoplasms; Combi | 1991 |
[A study on hepatic arterial infusion for metastatic liver tumor].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; | 1991 |
[Therapeutic effect of transarterial infusion immunochemotherapy for metastatic liver cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Administration | 1991 |
[Establishment of transplantable human colon cancer cell lines, chemosensitivity of colon carcinomas and the serially transplantable strains with MTT assay].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, An | 1991 |
A human colon cancer cell line established from collagen matrix cultures transplanted into nude mice.
Topics: Animals; Carcinoembryonic Antigen; Cell Line; Chromosome Aberrations; Chromosome Disorders; Collagen | 1991 |
[Experimental studies on subrenal capsule assay using cyclosporin A treated mice--the optimal treatment schedules of CsA and anticancer agents (mitomycin C and 5-fluorouracil)].
Topics: Animals; Body Weight; Breast Neoplasms; Colonic Neoplasms; Cyclosporins; Female; Fluorouracil; Human | 1990 |
Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colonic Neoplasm | 1990 |
[Methodological aspects on the histological evaluation of subrenal capsule assay (SRCA)].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyclophosphamide; Cyclosporins; Female; Fluoroura | 1990 |
Serious chemical sclerosing cholangitis associated with hepatic arterial 5FU and MMC chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cholangiopancreatography, Endoscopic Retrogra | 1990 |
The effect of recombinant interleukin 2 in combination with mitomycin C on advanced cancer.
Topics: Aged; Breast Neoplasms; Colonic Neoplasms; Combined Modality Therapy; Female; Humans; Immunization, | 1990 |
Mitomycin antibiotic reductive potential and related pharmacological activities.
Topics: Animals; Colonic Neoplasms; Electrochemistry; Humans; Kinetics; Liver; Mitomycin; Mitomycins; NADH D | 1990 |
[Long-term arterial infusion chemotherapy to the cancer patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Doxorubic | 1990 |
[An unresectable colon cancer with a diffuse metastases that turned resectable following thermotherapy with chemoimmunotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 1990 |
[Clinical studies of in vitro chemosensitivity test evaluated by ATP assay of gastrointestinal cancer].
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Scree | 1990 |
[Myelodysplastic syndrome (RAEB-T) occurring after adjuvant chemotherapy for colon and rectum cancers].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Cytarabine; DN | 1990 |
Increased mdr gene expression and decreased drug accumulation in a human colonic cancer cell line resistant to hydrophobic drug.
Topics: Antineoplastic Agents; Base Sequence; Biological Transport; Blotting, Northern; Blotting, Southern; | 1990 |
Antitumor activity of a derivative of mitomycin, 7-N-[2-[[2-(gamma-L-glutamylamino)ethyl]dithio]ethyl]mitomycin C (KW-2149), against murine and human tumors and a mitomycin C-resistant tumor in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Drug Screening Assay | 1990 |
[Intra-hepato-arterial infusion chemotherapy using catheter inserted and placed in hepatic artery via the left radial artery on liver malignancy].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; | 1990 |
[Analysis of the chemosensitivity test by subrenal capsule assay].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cisplatin; Colonic Neoplasms; Colony-Forming Units Assay; | 1987 |
Time-dependent interactions between 5-fluorouracil and mitomycin C on a human colon carcinoma cell line, HCT-8, in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Colonic Neoplasms; Drug Interactions; Flu | 1989 |
[An autopsy study of immunoblastic lymphadenopathy (IBL)-like T-cell lymphoma in a patient previously treated with chemotherapy in colon cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy; | 1989 |
Postoperative adjuvant chemotherapy and radiotherapy for cancer of the large bowel and rectum.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cecal Neoplasms; Colonic Neop | 1989 |
[Comparative study on the anticancer activities of KW2149 and mitomycin C against human tumor xenografts using subrenal capsule assay].
Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Humans; Mice; Mice, Inbred Strains; Mitomyc | 1989 |
Monitoring the effect of an anti-cancer drug on RPMI 4788 cells by a membrane potential probe, dis-C3-(5).
Topics: Antineoplastic Agents; Benzothiazoles; Carbocyanines; Cell Line; Colonic Neoplasms; Fluorescent Dyes | 1989 |
[Blood levels of mitomycin C in patients given by various routes of administration].
Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Depression, Chemical; Drug Administration Routes; | 1989 |
[Antitumor effect of alpha-difluoromethylornithine (DFMO) changes in ornithine decarboxylase (ODC) activity and polyamine (PA) levels in human tumor transplanted into nude mice].
Topics: Animals; Biogenic Polyamines; Breast Neoplasms; Colonic Neoplasms; Drug Screening Assays, Antitumor; | 1989 |
[A study of combined chemotherapy with MMC, ADM, CDDP, VP-16 and 5'DFUR (MAC-VD) in advanced cancers of digestive organs].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloni | 1989 |
[Two cases of digestive cancer demonstrated remarkable regression by hyperthermia with systemic chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Colonic N | 1989 |
[A 5-FU, ADR, MMC combined hepatic arterial infusion therapy in non-resectable liver metastases from colon and gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Evaluation; Flu | 1989 |
Malignant pseudomyxoma peritonei of colonic origin. Natural history and presentation of a curative approach to treatment.
Topics: Adenocarcinoma, Mucinous; Adult; Colonic Neoplasms; Combined Modality Therapy; Drug Therapy, Combina | 1987 |
Biological features and chemosensitivity of human colorectal cancer xenografted in nude mice.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Antineoplastic Agents; Carcinoembryonic Antigen; | 1987 |
[Combination chemotherapy of human gastrointestinal and breast cancer xenografts in nude mice with 5'-deoxy-5-fluorouridine and mitomycin C].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female | 1986 |
Adjuvant perioperative hepatic arterial mitomycin C and floxuridine combined with surgical resection of metastatic colorectal cancer in the liver.
Topics: Adult; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Combined Modality Therapy; Female; Floxuri | 1987 |
[Missile therapy using monoclonal antibody drug conjugates in colorectal carcinoma].
Topics: Adenocarcinoma; Aged; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Colonic Neoplasm | 1987 |
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neopla | 1987 |
[Effects of alternating chemotherapy with 2 non-cross-resistant drug combinations on human alimentary and breast cancer xenografts in nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neopla | 1987 |
Clinical application of monoclonal antibody-drug conjugates for immunotargeting chemotherapy of colorectal carcinoma.
Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Colonic Neoplasms; Drug E | 1988 |
New chemotherapeutic drug sensitivity assay for colon carcinomas in monolayer culture.
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Culture Techniques; Drug Resistance; Drug Scree | 1988 |
[Clinical application of monoclonal antibody-drug conjugates in colorectal carcinoma].
Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Colonic Neoplasms; Humans | 1988 |
[Our therapy concept in nonresectable liver metastases].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Com | 1988 |
Palliation of pelvic recurrence of colorectal cancer with intra-arterial 5-fluorouracil and mitomycin.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; C | 1985 |
[Growth rate of human colorectal cancer xenografted in nude mice].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Carcinoembryonic Antigen; Cell Division; Cell Lin | 1987 |
Treatment of metastatic colorectal cancer with hepatic artery combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Colonic Neoplasms; Fluorouracil; Follow- | 1986 |
Combination chemotherapy for advanced colorectal cancer. A pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Female; F | 1986 |
Pulmonary hypertension, hemolytic anemia, and renal failure. A mitomycin-associated syndrome.
Topics: Adenocarcinoma; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Colonic N | 1986 |
[Combination cancer chemotherapy of human gastric and colon carcinomas in nude mice--sequential cancer chemotherapy involving mitomycin C and tegafur].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; DNA, Neo | 1986 |
An aggressive, sequential combination chemotherapy regimen in the treatment of metastatic colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Response Relati | 1986 |
The efficacy of 5-fluorouracil, mitomycin C, and methyl CCNU in advanced colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Evaluation; Flu | 1986 |
[Surgery and adjuvant therapy of cancer of the large intestine].
Topics: BCG Vaccine; Colonic Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule | 1986 |
A syndrome of microangiopathic hemolytic anemia, renal impairment, and pulmonary edema in chemotherapy-treated patients with adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Female; Hemolytic-Uremic Syndrome; Humans; Hypoxia; | 1986 |
Microangiopathic hemolytic anemia, noncardiac pulmonary edema, and renal failure after treatment of metastatic adenocarcinoma of the colon with 5-fluorouracil and mitomycin-C: report of a case.
Topics: Adenocarcinoma; Anemia, Hemolytic; Colonic Neoplasms; Female; Fluorouracil; Humans; Kidney Failure, | 1986 |
[Combined effect of PT-050 (recombinant human TNF) and antitumor drugs on syngeneic murine tumors].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Doxo | 1986 |
Enhanced chemosensitivity of cells from malignant effusions under condition of exposure to high temperature.
Topics: Ascitic Fluid; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Colony-Forming Units Assay; Dox | 1986 |
Overcoming mitomycin C resistance with semisynthetic derivatives.
Topics: Animals; Biotransformation; Carcinoma; Cell Line; Colonic Neoplasms; DNA; Drug Resistance; Humans; M | 1986 |
[A model for the sensitivity determination of anticancer agents against human cancer using nude mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Cell Line; Cisplatin; Colonic Neoplas | 1987 |
[Application of cytopathology in a sensitivity test for anti-tumor agents. I. An experimental study].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Colony-Forming Units Assay; Cytologica | 1987 |
[Subrenal capsule assay for chemosensitivity testing].
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Colony-Forming Units Assay; Cyclophosphamide; Dox | 1987 |
[Effect of combination of UFT and MMC (UFT-M therapy) on human colonic cancer xenotransplanted into nude mice].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Colonic Neoplasms; Drug Admi | 1987 |
Mitomycin C pharmacokinetics in patients with recurrent or metastatic colorectal carcinoma.
Topics: Aged; Chromatography, High Pressure Liquid; Colonic Neoplasms; Half-Life; Humans; Kidney; Kinetics; | 1987 |
Rationale and indications for perfusion in liver tumors: current data.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusio | 1987 |
Liver metastasis of colon 26 cells implanted into the superior mesenteric vein in mice.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Disease Models, Animal; Injections, Intravenous; Liver N | 1987 |
Molecular comparisons of acquired and native mitomycin C resistance in human colon carcinoma cells.
Topics: Biotransformation; Colonic Neoplasms; Drug Resistance; Glycoconjugates; Humans; Isoelectric Point; M | 1987 |
[Subrenal capsule assay as a chemosensitivity test (V)--Experimental chemotherapy of cyclosporin A-treated mice and nude mice].
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Cy | 1988 |
Phase II study of a 5-fluorouracil, teniposide and mitomycin-C combination chemotherapy in advanced colorectal carcinomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Colonic Neoplasms; Diarrhea; D | 1988 |
[Intra-arterial chemotherapy of colorectal liver metastases with 5-fluorouracil (5-FU) and mitomycin C (MMC)].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Fluorouracil | 1987 |
Colorectal carcinoma in vitro is more sensitive to 1-hexylcarbamoyl-5-fluorouracil compared with six other antitumor drugs: carboquone, Adriamycin, mitomycin C, aclacinomycin A, cisplatin, 5-fluorouracil.
Topics: Aclarubicin; Antineoplastic Agents; Carbazilquinone; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug | 1988 |
[Changes in two-dimensional gel electrophoretic patterns of cellular protein spots in tumors after administration of mitomycin C].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Female; Mice; Mice, | 1988 |
[Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Colonic Neoplasms; Combined Modality Th | 1988 |
[Effect of UFTM therapy on primary and metastatic colon cancer of human xenotransplanted in nude mice].
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Hu | 1988 |
[Anticancer activities of a new mitomycin derivative KW 2149, against human tumors xenografted into nude mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Infusions, Parenteral; Lethal Dos | 1988 |
Hepatobiliary scintigraphy in patients receiving hepatic artery infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cholecystitis; Colonic Neoplasms; Do | 1985 |
[Prevention of immunodeficiency induced by cancer chemotherapy with BCG].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Colonic Neoplasms; Cytarabine; Fe | 1988 |
[Transcatheter arterial chemoembolization and selective hepatic arterial infusion using totally implantable reservoir].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Embolization, Therap | 1988 |
Potent effects of the monoclonal antibody-mitomycin C conjugate on human colon cancers.
Topics: Animals; Antibodies, Monoclonal; Colonic Neoplasms; Colony-Forming Units Assay; Humans; Immunotoxins | 1987 |
[Preliminary results of a phase II study of 5-FU, adriamycin, and mitomycin C (FAM) in combined hepatic infusion in patients with non-resectable metastatic liver cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Dr | 1987 |
[The effect and CT imaging of FAM hepatic infusion chemotherapy in patients with liver metastasis from colorectal carcinoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Female; Fluorouracil | 1987 |
Circumvention of deficient activation in mitomycin C-resistant human colonic carcinoma cells by the mitomycin C analogue BMY25282.
Topics: Animals; Biotransformation; Colonic Neoplasms; Drug Resistance; Humans; Microsomes, Liver; Mitomycin | 1986 |
Phase II study of hepatic artery infusion with 5-fluorouracil, adriamycin, and mitomycin C (FAM) in liver metastases from colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Doxorubicin; Drug Ev | 1986 |
Mitomycin and methotrexate: negative experience in untreated colorectal carcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Female; Hem | 1985 |
[Assessment of the combined effects of mitomycin C with alpha-interferon or gamma-interferon by the clonogenic assay technique].
Topics: Animals; Cell Line; Colonic Neoplasms; Colony-Forming Units Assay; Drug Synergism; Humans; Interfero | 1985 |
[Fluctuations of cancer tissue cell proteins determined by two-dimensional electrophoresis before and after antineoplastic agent administration--indices of the efficacy of antineoplastic agents].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; DNA Replication; Electrophoresis; Female; Humans; Mice; | 1985 |
Erosive gastroduodenitis with marked epithelial atypia after hepatic arterial infusion chemotherapy.
Topics: Adenocarcinoma; Aluminum; Cimetidine; Colonic Neoplasms; Fluorouracil; Gastric Mucosa; Humans; Infus | 1985 |
Enhancement of antitumor effect of cytotoxic agents by bestatin.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cisplatin; Colonic Neop | 1985 |
Long-term survivors of colorectal cancer with unresectable hepatic metastases.
Topics: Administration, Oral; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Fluorouracil; Human | 1985 |
Pelvic intra-arterial mitomycin C infusion in previously treated patients with metastatic, unresectable, pelvic colorectal cancer and angiographic determination of tumor vascularity.
Topics: Adult; Aged; Angiography; Cellulitis; Colonic Neoplasms; Female; Humans; Infusions, Intra-Arterial; | 1985 |
[Colony assay for clinical application].
Topics: Adult; Agar; Aged; Antineoplastic Agents; Cell Count; Cell Division; Cells, Cultured; Colonic Neopla | 1985 |
[A long survival case of carcinoma of the colon with hepatic metastasis following intra-arterial infusion chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Calcinosis; Colonic Neoplasms; Fluor | 1985 |
Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C.
Topics: Autoradiography; Cell Line; Colonic Neoplasms; Cytosol; Drug Resistance; Electrophoresis, Polyacryla | 1985 |
[Coexisting malignant lymphoma and advanced adenocarcinoma of the colon--a case report].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Cyclophosphamide; | 1985 |
[Intra-arterial continuous infusion in patients with advanced and recurrent cancer of the digestive system].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co | 1985 |
Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cells, Cultured; Colonic Neoplasms; DNA; Drug Res | 1985 |
[Multimodality therapy of colorectal cancer].
Topics: Aged; Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Administration Schedule; Emboliz | 1985 |
In vitro chemosensitivity tests on human tumor xenografts by clonogenic assay: the combined use of mitomycin C with alpha-interferon or gamma-interferon.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Colony-Forming Units Assay; | 1985 |
Spontaneous and mitomycin C induced structural chromosome aberrations in lymphocyte cultures from patients with adenomatosis of the colon and rectum.
Topics: Adenoma; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Cells, Cultured; Chromosome Aberratio | 1985 |
[A clinical trial of a new mitomycin C derivative, KW-2083 (7-N-(p-hydroxyphenyl)-mitomycin C)].
Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Biliary Tract Neoplasms; Colonic Neoplasms; Colon | 1985 |