Page last updated: 2024-11-06

mitomycin and Colitis

mitomycin has been researched along with Colitis in 5 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Mitomycin C did not produce inflammation in experimentally bypassed segments of small bowel despite the presence of colonic-type bacteria, suggesting that lack of intraluminal bacteria was not responsible for the absence of inflammation in the small intestine."5.28Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. ( Doria, MI; Gaginella, T; Hecht, D; Holmes, EW; Ibrahim, C; Kanofsky, JR; Keshavarzian, A; List, T; Sedghi, S; Urban, G, 1992)
" In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis."3.74Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008)
"Colitis was induced by administration of 5% dextran sodium sulphate in the drinking water or by one intraperitoneal injection of mitomycin C, 3."3.73Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat. ( Hare, K; Hartmann, B; Kissow, H; Poulsen, SS; Thim, L, 2005)
"This study investigated capillary blood flow (CBF) and pathomorphological alterations in the mucosa of different bowel segments at different times after disease onset in rats with colitis induced by either trinitrobenzensulfonic acid (TNBS) or mitomycin-C."3.71Changes of colonic mucosal microcirculation and histology in two colitis models: an experimental study using intravital microscopy and a new histological scoring system. ( Buhr, HJ; Foitzik, T; Hübotter, A; Kruschewski, M; Perez-Cantó, A, 2001)
"Mitomycin C did not produce inflammation in experimentally bypassed segments of small bowel despite the presence of colonic-type bacteria, suggesting that lack of intraluminal bacteria was not responsible for the absence of inflammation in the small intestine."1.28Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. ( Doria, MI; Gaginella, T; Hecht, D; Holmes, EW; Ibrahim, C; Kanofsky, JR; Keshavarzian, A; List, T; Sedghi, S; Urban, G, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poulsen, SS1
Kissow, H1
Hare, K1
Hartmann, B1
Thim, L1
Wang, X1
Zhao, L1
Han, T1
Chen, S1
Wang, J1
Kachur, JF1
Keshavarzian, A2
Sundaresan, R1
Doria, M1
Walsh, R1
de las Alas, MM1
Gaginella, TS1
Kruschewski, M1
Foitzik, T1
Perez-Cantó, A1
Hübotter, A1
Buhr, HJ1
Doria, MI1
Sedghi, S1
Kanofsky, JR1
Hecht, D1
Holmes, EW1
Ibrahim, C1
List, T1
Urban, G1
Gaginella, T1

Other Studies

5 other studies available for mitomycin and Colitis

ArticleYear
Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat.
    Regulatory peptides, 2005, Mar-30, Volume: 126, Issue:3

    Topics: Animals; Catheterization; Colitis; Colon; Dextran Sulfate; Dimerization; Disease Models, Animal; Fem

2005
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
    European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti

2008
Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa.
    Inflammation, 1995, Volume: 19, Issue:2

    Topics: Alprostadil; Animals; Anions; Bradykinin; Carbachol; Colitis; Intestinal Mucosa; Male; Mitomycin; Ne

1995
Changes of colonic mucosal microcirculation and histology in two colitis models: an experimental study using intravital microscopy and a new histological scoring system.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:11

    Topics: Animals; Colitis; Colon; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Microcirculation; Mit

2001
Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species.
    The Journal of laboratory and clinical medicine, 1992, Volume: 120, Issue:5

    Topics: Animals; Cell Membrane Permeability; Colitis; Colon; Dose-Response Relationship, Drug; Female; Free

1992