mitomycin has been researched along with Colitis in 5 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitomycin C did not produce inflammation in experimentally bypassed segments of small bowel despite the presence of colonic-type bacteria, suggesting that lack of intraluminal bacteria was not responsible for the absence of inflammation in the small intestine." | 5.28 | Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. ( Doria, MI; Gaginella, T; Hecht, D; Holmes, EW; Ibrahim, C; Kanofsky, JR; Keshavarzian, A; List, T; Sedghi, S; Urban, G, 1992) |
| " In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
| "Colitis was induced by administration of 5% dextran sodium sulphate in the drinking water or by one intraperitoneal injection of mitomycin C, 3." | 3.73 | Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat. ( Hare, K; Hartmann, B; Kissow, H; Poulsen, SS; Thim, L, 2005) |
| "This study investigated capillary blood flow (CBF) and pathomorphological alterations in the mucosa of different bowel segments at different times after disease onset in rats with colitis induced by either trinitrobenzensulfonic acid (TNBS) or mitomycin-C." | 3.71 | Changes of colonic mucosal microcirculation and histology in two colitis models: an experimental study using intravital microscopy and a new histological scoring system. ( Buhr, HJ; Foitzik, T; Hübotter, A; Kruschewski, M; Perez-Cantó, A, 2001) |
| "Mitomycin C did not produce inflammation in experimentally bypassed segments of small bowel despite the presence of colonic-type bacteria, suggesting that lack of intraluminal bacteria was not responsible for the absence of inflammation in the small intestine." | 1.28 | Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. ( Doria, MI; Gaginella, T; Hecht, D; Holmes, EW; Ibrahim, C; Kanofsky, JR; Keshavarzian, A; List, T; Sedghi, S; Urban, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poulsen, SS | 1 |
| Kissow, H | 1 |
| Hare, K | 1 |
| Hartmann, B | 1 |
| Thim, L | 1 |
| Wang, X | 1 |
| Zhao, L | 1 |
| Han, T | 1 |
| Chen, S | 1 |
| Wang, J | 1 |
| Kachur, JF | 1 |
| Keshavarzian, A | 2 |
| Sundaresan, R | 1 |
| Doria, M | 1 |
| Walsh, R | 1 |
| de las Alas, MM | 1 |
| Gaginella, TS | 1 |
| Kruschewski, M | 1 |
| Foitzik, T | 1 |
| Perez-Cantó, A | 1 |
| Hübotter, A | 1 |
| Buhr, HJ | 1 |
| Doria, MI | 1 |
| Sedghi, S | 1 |
| Kanofsky, JR | 1 |
| Hecht, D | 1 |
| Holmes, EW | 1 |
| Ibrahim, C | 1 |
| List, T | 1 |
| Urban, G | 1 |
| Gaginella, T | 1 |
5 other studies available for mitomycin and Colitis
| Article | Year |
|---|---|
Luminal and parenteral TFF2 and TFF3 dimer and monomer in two models of experimental colitis in the rat.
Topics: Animals; Catheterization; Colitis; Colon; Dextran Sulfate; Dimerization; Disease Models, Animal; Fem | 2005 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa.
Topics: Alprostadil; Animals; Anions; Bradykinin; Carbachol; Colitis; Intestinal Mucosa; Male; Mitomycin; Ne | 1995 |
Changes of colonic mucosal microcirculation and histology in two colitis models: an experimental study using intravital microscopy and a new histological scoring system.
Topics: Animals; Colitis; Colon; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Microcirculation; Mit | 2001 |
Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species.
Topics: Animals; Cell Membrane Permeability; Colitis; Colon; Dose-Response Relationship, Drug; Female; Free | 1992 |