mitomycin has been researched along with Cicatrix in 115 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 8.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "To investigate the efficacy of nintedanib on preventing postoperative scar in formation following glaucoma filtering surgery (GFC) in rabbits in comparison with Mitomycin-C (MMC)." | 8.31 | The anti-scar effect of tyrosine-kinase inhibitor nintedanib in experimental glaucoma filtration surgery in rabbits. ( Demirci Küçük, K; Furat Rençber, S; Öztürk, A; Yazır, Y; Yüksel, N; Yüksel, R, 2023) |
| "The gold standard for managing postoperative ocular fibrosis in glaucoma surgery is the chemotherapeutic mitomycin C (MMC) despite its association with significant adverse effects." | 8.31 | ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts. ( Armstrong, JJ; Denstedt, J; Hutnik, CML; Liu, H; Teplitsky, JE; Vinokurtseva, A, 2023) |
| "Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated." | 7.81 | Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE. ( Cai, J; Cao, X; Fu, Y; Ge, Y; Lu, C; Shi, K; Sun, Y; Yan, L, 2015) |
| "The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC)." | 7.78 | Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery. ( Arslan, S; Aydemir, O; Dağlı, AF; Güler, M, 2012) |
| "To investigate whether topical administration of pirfenidone eye drops could be used to prevent postoperative scarring in a rabbit model of experimental glaucoma filtration surgery." | 7.77 | Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. ( Lin, X; Sun, G; Wu, K; Yu, M; Zhong, H, 2011) |
| "To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS)." | 7.73 | Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery. ( Khaw, PT; Mead, AL; Wong, TT, 2005) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 7.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To demonstrate the potential use of Mitomycin-C (MMC) in the treatment of difficult and recurrent tracheal stenosis." | 7.70 | Mitomycin-C in the treatment of tracheal cicatrix after tracheal reconstruction. ( April, MM; Ward, RF, 1998) |
| "To evaluate the efficiency of mitomycin C (MMC) in limiting the postoperative inflammatory response and scarring after strabismus surgery." | 7.70 | Histologic effect of mitomycin C on strabismus surgery in the rabbit. ( Akaishi, PM; De Luca, IM; Minguini, N; Monteiro de Carvalho, KM, 2000) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 7.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "The study was designed to observe the effect of heterogeneous scleral transplantation in treatment of hypotony after filtration surgery of glaucoma with mitomycin C." | 7.69 | [The effect of heterogeneous scleral transplantation on hypotony after filtration surgery of glaucoma with mitomycin C]. ( Dong, Q; Yan, L; Zhang, S, 1997) |
| "Mitomycin-C is an antineoplastic antibiotic that acts as an alkylating agent by inhibiting DNA and protein synthesis." | 6.70 | Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. ( Healy, GB; Rahbar, R; Shapshay, SM, 2001) |
| "To determine the anticicatrization effect of mytomycin C (MMC)." | 6.68 | [The effect of mitomycin C on filtration surgery of glaucoma with poor prognosis]. ( Wu, L; Yin, J, 1996) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 6.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Trabeculectomy is performed as a treatment for glaucoma to lower the intraocular pressure (IOP)." | 6.43 | Intra-operative mitomycin C for glaucoma surgery. ( Indar, A; Wilkins, M; Wormald, R, 2005) |
| "Mitomycin C is an antimetabolite applied between the sclera and conjunctiva during the initial stages of a trabeculectomy to prevent excessive post-operative scarring and thus reduce the risk of failure." | 6.41 | Intra-operative mitomycin C for glaucoma surgery. ( Indar, A; Wilkins, M; Wormald, R, 2001) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 6.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery." | 5.72 | Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022) |
| "MRI showed that the scar adhesion and scar area of the MMC-PLA group were significantly reduced compared with those of the PLA, MMC, and saline groups." | 5.46 | Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs. ( Gu, Y; Liu, J; Tang, F; Wang, BB; Wu, J; Wu, T; Xie, H; Xie, N, 2017) |
| "Epineural scar formation after peripheral nerve surgery may be reduced by using topical application of mitomycin C and daunorubicin." | 5.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "The scleral punch provides a safe and effective method for constructing and revising full-thickness sclerectomies in the nanophthalmic eye, minimizing the risk of choroidal trauma." | 5.35 | Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome. ( MacLaren, RE; Sabrosa, NA; Smith, HB, 2009) |
| "Mitomycin-C was administered to the injured urethra in the form of irrigation for 5 min." | 5.32 | Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture. ( Ayyildiz, A; Caydere, M; Erol, D; Germiyanoglu, C; Gülerkaya, B; Nuhoglu, B; Ustün, H, 2004) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 4.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "The gold standard for managing postoperative ocular fibrosis in glaucoma surgery is the chemotherapeutic mitomycin C (MMC) despite its association with significant adverse effects." | 4.31 | ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts. ( Armstrong, JJ; Denstedt, J; Hutnik, CML; Liu, H; Teplitsky, JE; Vinokurtseva, A, 2023) |
| "To investigate the efficacy of nintedanib on preventing postoperative scar in formation following glaucoma filtering surgery (GFC) in rabbits in comparison with Mitomycin-C (MMC)." | 4.31 | The anti-scar effect of tyrosine-kinase inhibitor nintedanib in experimental glaucoma filtration surgery in rabbits. ( Demirci Küçük, K; Furat Rençber, S; Öztürk, A; Yazır, Y; Yüksel, N; Yüksel, R, 2023) |
| " Thirty patients underwent primary pterygium excision with adjuvant topical mitomycin-C application were followed up and imaged with Pentacam system at postoperative weeks 1, 4, 12 and month 18." | 3.91 | Novel grid and sectoral analyses in monitoring corneal scars. ( Belin, MW; Kam, KW; Kwok, RPW; Li, A; Young, AL, 2019) |
| "Mitomycin C (MMC) is known to reduce epidural fibrosis, but the underlying mechanisms have not yet been elucidated." | 3.81 | Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE. ( Cai, J; Cao, X; Fu, Y; Ge, Y; Lu, C; Shi, K; Sun, Y; Yan, L, 2015) |
| "2 mg/mL mitomycin C may provide initial and transient stimulation of collagen for necessary repair to damaged tissue without the long-term risk of fibrosis." | 3.80 | Dose-dependent effect of mitomycin C on human vocal fold fibroblasts. ( Chen, F; Dikkers, FG; Li, NY; Thibeault, SL, 2014) |
| "This study was undertaken to evaluate the efficacy of co-treatment with suberoylanilide hydroxamic acid (SAHA) and mitomycin-C (MMC) on corneal fibrosis in an in-vivo model." | 3.80 | The efficacy of co-treatment with suberoylanilide hydroxamic acid and mitomycin C on corneal scarring after therapeutic keratectomy: an animal study. ( Kim, SW; Park, WC; Woo, JE; Yoo, YH, 2014) |
| "The aim of this study is to demonstrate a drug delivery system with the capacity to adjust the release of mitomycin C (MMC), based on polymer composition, and inhibit fibroblast proliferation to a better effect than is currently used in glaucoma filtration surgery." | 3.79 | Adjustable release of mitomycin C for inhibition of scar tissue formation after filtration surgery. ( Merritt, SR; Velasquez, G; von Recum, HA, 2013) |
| "The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC)." | 3.78 | Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery. ( Arslan, S; Aydemir, O; Dağlı, AF; Güler, M, 2012) |
| "Mitomycin C was applied in the median frontal drainage pathway of a 44-year-old woman suffering from recalcitrant chronic frontal sinusitis." | 3.77 | Safe application of mitomycin C within the nasal cavity. ( Gutierrez, T; Hopkins, C, 2011) |
| "To investigate whether topical administration of pirfenidone eye drops could be used to prevent postoperative scarring in a rabbit model of experimental glaucoma filtration surgery." | 3.77 | Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery. ( Lin, X; Sun, G; Wu, K; Yu, M; Zhong, H, 2011) |
| "To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS)." | 3.73 | Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery. ( Khaw, PT; Mead, AL; Wong, TT, 2005) |
| "To investigate the comparative efficacy and safety of deep sclerectomy with and without intraoperative mitomycin C (MMC) application for lowering the intraocular pressure (IOP)." | 3.73 | Deep sclerectomy augmented with mitomycin C. ( Anand, N; Atherley, C, 2005) |
| "The role of topically applied mitomycin C in preventing postoperative perineural fibrosis was examined by gross anatomical dissection and histological analysis in rats." | 3.73 | Topical application of mitomycin C prevents epineural scar formation in rats. ( Ceylan, S; Etus, V; Ilbay, G; Ilbay, K; Yildiz, K, 2005) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 3.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To demonstrate the potential use of Mitomycin-C (MMC) in the treatment of difficult and recurrent tracheal stenosis." | 3.70 | Mitomycin-C in the treatment of tracheal cicatrix after tracheal reconstruction. ( April, MM; Ward, RF, 1998) |
| "To evaluate the efficiency of mitomycin C (MMC) in limiting the postoperative inflammatory response and scarring after strabismus surgery." | 3.70 | Histologic effect of mitomycin C on strabismus surgery in the rabbit. ( Akaishi, PM; De Luca, IM; Minguini, N; Monteiro de Carvalho, KM, 2000) |
| "Mitomycin C trabeculectomy after dissection of conjunctival scar tissue may be useful for treating refractory glaucoma." | 3.70 | Mitomycin C trabeculectomy in eyes with cicatricial conjunctiva. ( Honda, Y; Honjo, M; Inatani, M; Tanihara, H, 1998) |
| "The study was designed to observe the effect of heterogeneous scleral transplantation in treatment of hypotony after filtration surgery of glaucoma with mitomycin C." | 3.69 | [The effect of heterogeneous scleral transplantation on hypotony after filtration surgery of glaucoma with mitomycin C]. ( Dong, Q; Yan, L; Zhang, S, 1997) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 3.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "Mitomycin-C is an effective adjuvant treatment method in the management of BCAS." | 2.77 | [Effect of topical application with mitomycin C in the management of benign cicatricial airway stenosis]. ( Cui, J; Pei, YH; Wang, J; Wang, T; Xu, M; Zhang, CY; Zhang, J, 2012) |
| "Mitomycin C (MMC) is an antibiotic-antineoplastic agent that decreases fibroblast proliferation and scar formation." | 2.72 | Effect of mitomycin C on the size of antrostomy after endoscopic sinus surgery. ( Cha, HE; Chung, YS; Gang, IG; Ha, JS; Kim, ST, 2006) |
| "The results of this study indicate that topical mitomycin C on Gelfoam applied in the middle ear appears safe when low concentrations are used, even in the rat, which has a higher susceptibility to gentamycin toxicity than humans." | 2.71 | Otologic effects of topical mitomycin C: phase I-evaluation of ototoxicity. ( Babu, SC; Kartush, JM; Patni, A, 2005) |
| "Fifteen patients; choanal atresia in 5 patients, airway stenosis in 8 patients, hypopharyngeal stenosis in 1 patient, and esophageal stenosis in 1 patient." | 2.70 | The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe? ( Healy, GB; Jones, DT; Kenna, MA; McGill, TJ; Nuss, RC; Rahbar, R; Roberson, DW, 2002) |
| "Mitomycin-C is an antineoplastic antibiotic that acts as an alkylating agent by inhibiting DNA and protein synthesis." | 2.70 | Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications. ( Healy, GB; Rahbar, R; Shapshay, SM, 2001) |
| "To determine the anticicatrization effect of mytomycin C (MMC)." | 2.68 | [The effect of mitomycin C on filtration surgery of glaucoma with poor prognosis]. ( Wu, L; Yin, J, 1996) |
| "However scarring during wound healing can block this channel which will lead to the operation failing." | 2.53 | Anti-vascular endothelial growth factor for control of wound healing in glaucoma surgery. ( Cheng, JW; Cheng, SW; Lu, GC; Wei, RL, 2016) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 2.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar." | 2.46 | The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review. ( Basdag, B; Magarakis, M; Manson, PN; Rosson, GD; Shridharani, SM; Singh, NK, 2010) |
| "The healing and scarring determine the percentage of patients achieving low final intraocular pressures (IOPs) that are associated with virtually no glaucoma progression." | 2.44 | Modulation of wound healing during and after glaucoma surgery. ( Brocchini, S; Dahlmann-Noor, A; Georgoulas, S; Khaw, PT, 2008) |
| "Mitomycin C has been used successfully in various ophthalmologic and, more recently, otolaryngologic procedures." | 2.44 | Mitomycin C and endoscopic sinus surgery: where are we? ( Anand, VK; Brown, SM; Tabaee, A, 2007) |
| "Vocal fold scarring still remains a therapeutic challenge, with the most problematic issue being the histologic changes that are primarily responsible for altering the viscoelasticity of the vocal fold mucosa." | 2.43 | Current treatment of vocal fold scarring. ( Hirano, S, 2005) |
| "Mitomycin C (MMC) has been described as having a positive effect in different types of dacryocystorhinostomy (DCR) surgery such as external DCR, endonasal and transcanalicular DCR." | 2.43 | [Use of mitomycin C (MMC) for dacryocystorhinostomy interventions]. ( Adenis, JP; Robert, PY; Sommer, U, 2005) |
| "Trabeculectomy is performed as a treatment for glaucoma to lower the intraocular pressure (IOP)." | 2.43 | Intra-operative mitomycin C for glaucoma surgery. ( Indar, A; Wilkins, M; Wormald, R, 2005) |
| "Mitomycin C is an antimetabolite applied between the sclera and conjunctiva during the initial stages of a trabeculectomy to prevent excessive post-operative scarring and thus reduce the risk of failure." | 2.41 | Intra-operative mitomycin C for glaucoma surgery. ( Indar, A; Wilkins, M; Wormald, R, 2001) |
| "The use of antiscarring agents, particularly the antimetabolites 5-fluorouracil and mitomycin C, have revolutionized glaucoma surgery over the past decade." | 2.39 | Current techniques in wound healing modulation in glaucoma surgery. ( Khaw, PT; Migdal, CS, 1996) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 2.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "Post-surgical scarring is a known cause of trabeculectomy failure." | 1.91 | Clinical and Histopathological Effects of Intracameral Ranibizumab in Experimental Trabeculectomy. ( Azhany, Y; Che Hamzah, J; Jaafar, H; Liza-Sharmini, AT; Low, JH; Rahman, WFWA; Yusuf, WNW, 2023) |
| "Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery." | 1.72 | Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022) |
| "Treatment of tracheal stenosis is occasionally performed in combination with wound healing modulators to manipulate new extracellular matrix (ECM) formation and prevent fibrosis." | 1.56 | Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection. ( Baltazares-Lipp, M; Baltazares-Lipp, ME; Gaxiola-Gaxiola, M; González-González, AI; Hernández-Jiménez, C; Iñiguez-García, MA; Jasso-Victoria, R; Luna-Flores, A; Olmos-Zuñiga, JR; Silva-Martínez, M; Solis-Alanis, N; Vázquez-Minero, JC, 2020) |
| "Mitomycin C (MMC) has been demonstrated to have significant inhibitory effects on epidural scar." | 1.46 | MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy. ( Cao, X; Geng, D; Jiang, L; Liu, J; Qin, J; Shen, X; Wang, B; Wu, T; Xie, H; Yu, C; Yuan, T, 2017) |
| "MRI showed that the scar adhesion and scar area of the MMC-PLA group were significantly reduced compared with those of the PLA, MMC, and saline groups." | 1.46 | Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs. ( Gu, Y; Liu, J; Tang, F; Wang, BB; Wu, J; Wu, T; Xie, H; Xie, N, 2017) |
| "Epineural scar formation after peripheral nerve surgery may be reduced by using topical application of mitomycin C and daunorubicin." | 1.43 | Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin. ( Ilbay, G; Ilbay, K; Vural, E; Yilmaz, M, 2016) |
| "7 % high dose), while both TGF-β3 dosage groups showed no significant change (65." | 1.40 | Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures. ( Chak, A; Cipriano, C; Lash, RH; Marks, JM; Ponsky, JL; Schomisch, SJ; Wu, Y, 2014) |
| "Choanal stenosis is a well recognized late complication of radiotherapy for nasopharyngeal carcinoma." | 1.39 | Velopharyngeal and choanal stenosis after radiotherapy for nasopharyngeal carcinoma. ( Chong, AW; Hussein, J; Narayanan, P; Omar, R; Tan, TS, 2013) |
| "The frequency of LT1009 dosage was determined initially using an enzyme-linked immunosorbent assay assay measuring LT1009 eye tissue retention in 6 New Zealand White rabbits." | 1.39 | Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model. ( Beattie, AR; Levine, MA; Lukowski, ZL; Meyers, CA; Min, J; Samuelson, DA; Schultz, GS; Sherwood, MB; Stoller, G, 2013) |
| "Mitomycin C-treated HTFs were used for comparison." | 1.38 | In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin C. ( Seet, LF; Su, R; Toh, LZ; Wong, TT, 2012) |
| "Mitomycin C (MMC) could also reduce the scar formation after surgery, but cytotoxicity and the administrative pathway prevent its application." | 1.36 | Mitomycin C-polyethylene glycol controlled-release film inhibits collagen secretion and induces apoptosis of fibroblasts in the early wound of a postlaminectomy rat model. ( Cao, X; Liu, J; Ni, B; Yang, J; Zhou, W; Zhu, L, 2010) |
| "Mitomycin C (MMC) is used clinically to treat corneal scarring in human patients." | 1.36 | Efficacy and safety of mitomycin C as an agent to treat corneal scarring in horses using an in vitro model. ( Buss, DG; Giuliano, EA; Mohan, RR; Sharma, A, 2010) |
| "The area of epidural scar tissue and degree of epidural adhesion were determined by 7." | 1.36 | Study on the optimal concentration of topical mitomycin-C in preventing postlaminectomy epidural adhesion. ( Cao, X; Lu, S; Su, C; Teng, G; Yao, C; Zang, F; Zhang, A, 2010) |
| "Intraocular pressure was measured before and three weeks after surgery." | 1.35 | Effects of mitomycin C on the expression of chymase and mast cells in the conjunctival scar of a monkey trabeculectomy model. ( Fukmoto, M; Ikeda, T; Ishida, O; Jin, D; Miyazaki, M; Okada, K; Oku, H; Sugiyama, T; Takai, S, 2009) |
| "The scleral punch provides a safe and effective method for constructing and revising full-thickness sclerectomies in the nanophthalmic eye, minimizing the risk of choroidal trauma." | 1.35 | Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome. ( MacLaren, RE; Sabrosa, NA; Smith, HB, 2009) |
| "Acute airway obstruction may occur in MMC-treated rabbits with tracheal wounds." | 1.34 | Benefits and risks of mitomycin use in the traumatized tracheal mucosa. ( Kim, DH; Kim, KH; Park, CI; Rha, KS; Roh, JL; Sung, MW, 2007) |
| "Mitomycin-C release was measured in vitro using spectrophotometry." | 1.33 | [Dosage and kinetics of MMC release of a collagen implant used as a delivery device in glaucoma surgery in the rabbit eye]. ( Adjadj, E; Drewe, J; Flammer, J; Mermoud, A; Roy, S; Shaarawy, T; Zimmermann, C, 2006) |
| "Mitomycin-C was administered to the injured urethra in the form of irrigation for 5 min." | 1.32 | Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture. ( Ayyildiz, A; Caydere, M; Erol, D; Germiyanoglu, C; Gülerkaya, B; Nuhoglu, B; Ustün, H, 2004) |
| "Mitomycin C (MMC) is an antineoplastic agent with an antiproliferative effect on fibroblasts." | 1.31 | Mitomycin C in sinus surgery: preliminary results in a rabbit model. ( Ahmarani, C; Péloquin, L; Rahal, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (11.30) | 18.2507 |
| 2000's | 47 (40.87) | 29.6817 |
| 2010's | 47 (40.87) | 24.3611 |
| 2020's | 8 (6.96) | 2.80 |
| Authors | Studies |
|---|---|
| Vinokurtseva, A | 2 |
| Armstrong, JJ | 2 |
| Liu, H | 2 |
| Hutnik, CML | 2 |
| Wu, P | 1 |
| Wang, Z | 1 |
| Liang, L | 1 |
| Chen, B | 1 |
| Xu, N | 1 |
| Teplitsky, JE | 1 |
| Denstedt, J | 1 |
| Yüksel, R | 1 |
| Yüksel, N | 1 |
| Yazır, Y | 1 |
| Öztürk, A | 1 |
| Furat Rençber, S | 1 |
| Demirci Küçük, K | 1 |
| Azhany, Y | 1 |
| Rahman, WFWA | 1 |
| Jaafar, H | 1 |
| Low, JH | 1 |
| Yusuf, WNW | 1 |
| Liza-Sharmini, AT | 1 |
| Che Hamzah, J | 1 |
| Pal-Ghosh, S | 1 |
| Tadvalkar, G | 1 |
| Lieberman, VR | 1 |
| Guo, X | 1 |
| Zieske, JD | 1 |
| Hutcheon, A | 1 |
| Stepp, MA | 1 |
| de Oliveira, CM | 1 |
| Ferreira, JLM | 1 |
| Olmos-Zuñiga, JR | 1 |
| Baltazares-Lipp, M | 1 |
| Hernández-Jiménez, C | 1 |
| Jasso-Victoria, R | 1 |
| Gaxiola-Gaxiola, M | 1 |
| Silva-Martínez, M | 1 |
| Iñiguez-García, MA | 1 |
| González-González, AI | 1 |
| Vázquez-Minero, JC | 1 |
| Luna-Flores, A | 1 |
| Solis-Alanis, N | 1 |
| Baltazares-Lipp, ME | 1 |
| Luu, K | 1 |
| Tellez, PA | 1 |
| Chadha, NK | 1 |
| Xie, H | 2 |
| Wang, B | 1 |
| Shen, X | 1 |
| Qin, J | 1 |
| Jiang, L | 1 |
| Yu, C | 1 |
| Geng, D | 1 |
| Yuan, T | 1 |
| Wu, T | 2 |
| Cao, X | 4 |
| Liu, J | 3 |
| Wang, BB | 1 |
| Xie, N | 1 |
| Wu, J | 1 |
| Gu, Y | 1 |
| Tang, F | 1 |
| Pimentel, E | 1 |
| Schmidt, J | 1 |
| Kam, KW | 1 |
| Li, A | 1 |
| Kwok, RPW | 1 |
| Belin, MW | 1 |
| Young, AL | 1 |
| Kwok, SS | 1 |
| Shih, KC | 1 |
| Bu, Y | 1 |
| Lo, AC | 1 |
| Chan, TC | 1 |
| Lai, JS | 1 |
| Jhanji, V | 1 |
| Tong, L | 1 |
| Ali, MJ | 1 |
| Paulsen, F | 1 |
| Li, NY | 1 |
| Chen, F | 1 |
| Dikkers, FG | 2 |
| Thibeault, SL | 1 |
| Zarbin, MA | 1 |
| Merritt, SR | 1 |
| Velasquez, G | 1 |
| von Recum, HA | 1 |
| Fawaz, SA | 1 |
| Sabri, SM | 1 |
| Sweed, AS | 1 |
| Hegazi, MA | 1 |
| Riad, MA | 1 |
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24 reviews available for mitomycin and Cicatrix
| Article | Year |
|---|---|
Overview of cicatricial modulators in glaucoma fistulizing surgery.
Topics: Cicatrix; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Trabeculectomy; Wound Healing | 2020 |
The effectiveness of mitomycin C in Otolaryngology procedures: A systematic review.
Topics: Administration, Topical; Cicatrix; Humans; Mitomycin; Otorhinolaryngologic Diseases | 2022 |
Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma?
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Randomiz | 2018 |
Systematic Review on Therapeutic Strategies to Minimize Corneal Stromal Scarring After Injury.
Topics: Administration, Ophthalmic; Alkylating Agents; Cicatrix; Corneal Injuries; Corneal Stroma; Drug Ther | 2019 |
Ultrastructure of the lacrimal drainage system in health and disease: A major review.
Topics: Bacteria; Biofilms; Cicatrix; Constriction, Pathologic; Dacryocystorhinostomy; Fibrinolytic Agents; | 2019 |
[The mechanism and progress of topical application of mitomycin C as an adjunctive therapy for benign airway stenosis].
Topics: Administration, Inhalation; Administration, Topical; Airway Obstruction; Animals; Bronchoscopy; Cica | 2013 |
[Current surgical methods for advanced glaucoma].
Topics: Cicatrix; Glaucoma Drainage Implants; Glaucoma, Angle-Closure; Humans; Hungary; Intraocular Pressure | 2013 |
Clinical outcomes of dacryocystorhinostomy with or without intraoperative use of mitomycin C: a systematic review and meta-analysis.
Topics: Cicatrix; Dacryocystitis; Dacryocystorhinostomy; Drug Administration Schedule; Humans; Lacrimal Duct | 2014 |
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Press | 2015 |
Anti-vascular endothelial growth factor for control of wound healing in glaucoma surgery.
Topics: Angiogenesis Inhibitors; Bevacizumab; Cicatrix; Glaucoma; Humans; Intraocular Pressure; Mitomycin; R | 2016 |
Modulation of wound healing during and after glaucoma surgery.
Topics: Antibiotics, Antineoplastic; Cicatrix; Dendrimers; Fibroblasts; Filtering Surgery; Glaucoma; Humans; | 2008 |
Topical use of MMC in the upper aerodigestive tract: a review on the side effects.
Topics: Administration, Topical; Adolescent; Adult; Airway Obstruction; Animals; Child; Child, Preschool; Ci | 2010 |
The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review.
Topics: Antineoplastic Agents; Bleomycin; Cicatrix; Fluorouracil; Humans; Hypertrophy; Interferon-alpha; Kel | 2010 |
Current treatment of vocal fold scarring.
Topics: Antibiotics, Antineoplastic; Cicatrix; Decorin; Elasticity; Extracellular Matrix; Extracellular Matr | 2005 |
[Use of mitomycin C (MMC) for dacryocystorhinostomy interventions].
Topics: Cicatrix; Dacryocystorhinostomy; Humans; Lacrimal Apparatus Diseases; Mitomycin; Nucleic Acid Synthe | 2005 |
Intra-operative mitomycin C for glaucoma surgery.
Topics: Antimetabolites; Cicatrix; Glaucoma; Humans; Intraoperative Period; Mitomycin; Randomized Controlled | 2005 |
Mitomycin: clinical applications in ophthalmic practice.
Topics: Antibiotics, Antineoplastic; Cicatrix; Conjunctival Neoplasms; Glaucoma; Humans; Melanoma; Mitomycin | 2006 |
Mitomycin C and endoscopic sinus surgery: where are we?
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Endoscopy; Humans; Mitomycin; Nasal Mucosa; Paranasa | 2007 |
[Mitomycin C in head and neck surgical procedures].
Topics: Alkylating Agents; Animals; Cicatrix; DNA; Fibroblasts; Follow-Up Studies; Humans; Mitomycin; Otorhi | 2007 |
[Wound healing modulation in glaucoma surgery].
Topics: Adult; Animals; Cataract Extraction; Child; Cicatrix; Eye Diseases; Filtering Surgery; Fluorouracil; | 2007 |
Mitomycin C and airway surgery: how well does it work?
Topics: Administration, Topical; Airway Obstruction; Animals; Cicatrix; Humans; Mitomycin; Nucleic Acid Synt | 2008 |
[Mitomycin C in glaucoma surgery].
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Midd | 1993 |
Current techniques in wound healing modulation in glaucoma surgery.
Topics: Animals; Antimetabolites; Cataract Extraction; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; | 1996 |
Intra-operative mitomycin C for glaucoma surgery.
Topics: Antimetabolites; Cataract Extraction; Cicatrix; Glaucoma; Humans; Intraoperative Period; Mitomycin; | 2001 |
14 trials available for mitomycin and Cicatrix
| Article | Year |
|---|---|
Use of local mitomycin C in enhancing laryngeal healing after laser cordotomy: a prospective controlled study.
Topics: Adult; Alkylating Agents; Cicatrix; Female; Humans; Intraoperative Care; Laryngostenosis; Laser Ther | 2014 |
A novel technique for mitomycin-c application in frontal sinus surgery.
Topics: Administration, Topical; Adult; Aged; Chronic Disease; Cicatrix; Constriction, Pathologic; Cross-Ove | 2014 |
Effect of different application depths of mitomycin-C in deep sclerectomy with collagen implant: a randomized controlled trial.
Topics: Absorbable Implants; Aged; Aged, 80 and over; Cicatrix; Collagen; Female; Glaucoma, Open-Angle; Huma | 2009 |
Effect of doxycycline on postoperative scarring after trabeculectomy in an experimental rabbit model.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blister; Cicatrix; Conjunctiva; Doxycyc | 2010 |
[Effect of topical application with mitomycin C in the management of benign cicatricial airway stenosis].
Topics: Adult; Aged; Bronchoscopy; Cicatrix; Female; Humans; Male; Middle Aged; Mitomycin; Retrospective Stu | 2012 |
Otologic effects of topical mitomycin C: phase I-evaluation of ototoxicity.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Auditory Threshold; Cicatrix; Dose-Re | 2005 |
[Comparative study of amniotic membrane transplantation, with and without simultaneous application of mitomycin C in conjunctival fornix reconstruction].
Topics: Adult; Aged; Amnion; Cicatrix; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; Eye Bu | 2005 |
Effect of mitomycin C on the size of antrostomy after endoscopic sinus surgery.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Chronic Disease; Cica | 2006 |
[Results the application of mitomicyn during endonasal and endocanalicular dacryocystorhinostomy by diode laser].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cicatrix; Dacryocystorhinostomy; Double-Blind Method; Fe | 2006 |
[The effect of mitomycin C on filtration surgery of glaucoma with poor prognosis].
Topics: Adolescent; Adult; Child; Child, Preschool; Cicatrix; Female; Filtering Surgery; Follow-Up Studies; | 1996 |
Mini-trabeculectomy in eyes with high risk of scarring: midterm follow-up.
Topics: Aged; Aged, 80 and over; Cicatrix; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure | 2001 |
Mitomycin: effects on laryngeal and tracheal stenosis, benefits, and complications.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antimetabolites; Child; Child, Preschool; Cicatrix | 2001 |
Intraoperative mitomycin C in dacryocystorhinostomy.
Topics: Adolescent; Adult; Aged; Cicatrix; Dacryocystorhinostomy; Female; Humans; Intraoperative Care; Male; | 2001 |
The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe?
Topics: Administration, Topical; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Choanal At | 2002 |
77 other studies available for mitomycin and Cicatrix
| Article | Year |
|---|---|
Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery.
Topics: Aspirin; Cell Transdifferentiation; Cells, Cultured; Chromatography, Liquid; Cicatrix; Collagen; Cyt | 2022 |
Characteristics of Mitomycin C-Loaded Peptide Hydrogel
Topics: Animals; Cicatrix; Drug Delivery Systems; Hydrogels; Mitomycin; Peptides; Rats | 2023 |
ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts.
Topics: Cicatrix; Collagen; Fibroblasts; Glaucoma; Humans; Matrix Metalloproteinase 9; Mitomycin; Tenon Caps | 2023 |
The anti-scar effect of tyrosine-kinase inhibitor nintedanib in experimental glaucoma filtration surgery in rabbits.
Topics: Animals; Cicatrix; Conjunctiva; Fibrosis; Filtering Surgery; Glaucoma; Intraocular Pressure; Matrix | 2023 |
Clinical and Histopathological Effects of Intracameral Ranibizumab in Experimental Trabeculectomy.
Topics: Animals; Cicatrix; Intraocular Pressure; Mitomycin; Rabbits; Ranibizumab; Trabeculectomy | 2023 |
Transient Mitomycin C-treatment of human corneal epithelial cells and fibroblasts alters cell migration, cytokine secretion, and matrix accumulation.
Topics: Cell Movement; Cells, Cultured; Cicatrix; Collagen; Cornea; Cytokines; Epithelial Cells; Fibroblasts | 2019 |
Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection.
Topics: Anastomosis, Surgical; Animals; Cicatrix; Collagen; Decorin; Disease Models, Animal; Dogs; Extracell | 2020 |
MMC controlled-release membranes attenuate epidural scar formation in rat models after laminectomy.
Topics: Animals; Cicatrix; Delayed-Action Preparations; Disease Models, Animal; Epidural Space; Fibrosis; La | 2017 |
Controlled-release mitomycin C-polylactic acid film prevents epidural scar hyperplasia after laminectomy by inducing fibroblast autophagy and regulating the expression of miRNAs.
Topics: Animals; Autophagy; Cicatrix; Collagen; Delayed-Action Preparations; Drug Delivery Systems; Dura Mat | 2017 |
Novel grid and sectoral analyses in monitoring corneal scars.
Topics: Adult; Aged; Alkylating Agents; Analysis of Variance; Cicatrix; Cornea; Corneal Injuries; Densitomet | 2019 |
Mitomycin solution (Mitosol) for glaucoma surgery.
Topics: Cicatrix; Glaucoma; Humans; Mitomycin; Solutions | 2013 |
Dose-dependent effect of mitomycin C on human vocal fold fibroblasts.
Topics: Alkylating Agents; Blotting, Western; Cicatrix; Dose-Response Relationship, Drug; Fibrosis; Humans; | 2014 |
Combination therapy to reduce conjunctival scarring after glaucoma surgery.
Topics: Alkylating Agents; Apoptosis; Calcium Channel Blockers; Cicatrix; Conjunctival Diseases; Cyclosporin | 2013 |
Adjustable release of mitomycin C for inhibition of scar tissue formation after filtration surgery.
Topics: Cell Proliferation; Cicatrix; Drug Delivery Systems; Filtering Surgery; Glaucoma; Humans; Mitomycin; | 2013 |
[The application of mitomycin C in treatment of airway scarring stenosis].
Topics: Adolescent; Adult; Child; Cicatrix; Endoscopy; Female; Humans; Laryngostenosis; Male; Middle Aged; M | 2013 |
Preliminary results of antiscarring therapy in the prevention of postendoscopic esophageal mucosectomy strictures.
Topics: Angiogenesis Inhibitors; Animals; Cicatrix; Disease Models, Animal; Dissection; Drug Therapy, Combin | 2014 |
The efficacy of co-treatment with suberoylanilide hydroxamic acid and mitomycin C on corneal scarring after therapeutic keratectomy: an animal study.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Cicatrix; Corneal Diseases; Cytokin | 2014 |
Experimental research on the effect of mitomycin C fibrin gel on spinal peridural scar tissue in rats.
Topics: Adhesiveness; Animals; Cicatrix; Fibrin; Gels; Hydroxyproline; Male; Mitomycin; Rats; Rats, Sprague- | 2014 |
Effects of Gelatin Hydrogel Loading Mitomycin C on Conjunctival Scarring in a Canine Filtration Surgery Model.
Topics: Administration, Topical; Animals; Cicatrix; Conjunctiva; Conjunctival Diseases; Disease Models, Anim | 2015 |
Mitomycin C induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-200b and its targeting of RhoE.
Topics: Animals; Apoptosis; Cells, Cultured; Cicatrix; Down-Regulation; Epidural Space; Failed Back Surgery | 2015 |
Prevention of Epidural Fibrosis in Rats by Local Administration of Mitomycin C or Daunorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Daunorubicin; Disease Models, Animal; Female; Fibros | 2016 |
The Combination of PlGF Inhibition and MMC as a Novel Anti-Scarring Strategy for Glaucoma Filtration Surgery.
Topics: Animals; Anterior Chamber; Blood Proteins; Cicatrix; Disease Models, Animal; Filtering Surgery; Glau | 2016 |
[Therapeutic effects of chitosan/polyethylene glycols-succinate/mitomycin C film drug delivery system on epidural scarring tissues after laminectomy of SD rats].
Topics: Animals; Biocompatible Materials; Chitosan; Cicatrix; Disease Models, Animal; Drug Delivery Systems; | 2008 |
Scleral punch method with topical mitomycin C for safe revision of failed deep sclerectomy in nanophthalmic uveal effusion syndrome.
Topics: Administration, Topical; Body Fluids; Cicatrix; Female; Humans; Microphthalmos; Middle Aged; Mitomyc | 2009 |
[The topical application of mitomycin C in the treatment of scar formation and stenosis in hollow organs of the head and neck: a field report].
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Airway Obstruction; Antibiotics | 2009 |
Anterior segment optical coherence tomography for transepithelial phototherapeutic keratectomy in central corneal stromal scarring.
Topics: Anterior Eye Segment; Cicatrix; Corneal Diseases; Corneal Opacity; Corneal Stroma; Epithelium, Corne | 2009 |
Endoscopy-assisted surgery with topical mitomycin for a cholesterol granuloma in the petrous apex.
Topics: Administration, Topical; Cholesterol; Cicatrix; Endoscopy; Female; Follow-Up Studies; Granuloma, For | 2009 |
Effects of mitomycin C on the expression of chymase and mast cells in the conjunctival scar of a monkey trabeculectomy model.
Topics: Animals; Cell Adhesion; Chymases; Cicatrix; Conjunctiva; Fibrillar Collagens; Gene Expression Regula | 2009 |
Mitomycin C-polyethylene glycol controlled-release film inhibits collagen secretion and induces apoptosis of fibroblasts in the early wound of a postlaminectomy rat model.
Topics: Animals; Apoptosis; Cicatrix; Collagen; Delayed-Action Preparations; Drug Delivery Systems; Dura Mat | 2010 |
Study on the optimal concentration of topical mitomycin-C in preventing postlaminectomy epidural adhesion.
Topics: Administration, Topical; Animals; Cicatrix; Dose-Response Relationship, Drug; Epidural Space; Evoked | 2010 |
Adhesion reduction after knee surgery in a rat model by mitomycin C.
Topics: Animals; Cell Proliferation; Cicatrix; Disease Models, Animal; Female; Fibrosis; Foreign-Body Reacti | 2011 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fib | 2010 |
Efficacy and safety of mitomycin C as an agent to treat corneal scarring in horses using an in vitro model.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Cells, Cultured; Cicatrix; Corne | 2010 |
Safe application of mitomycin C within the nasal cavity.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chronic Disease; Cicatrix; Drug Deliver | 2011 |
Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery.
Topics: Actins; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Ce | 2011 |
Target drug delivery system as a new scarring modulation after glaucoma filtration surgery.
Topics: Chitosan; Cicatrix; Drug Carriers; Drug Delivery Systems; Fibrinolytic Agents; Fibrosis; Filtering S | 2011 |
In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin C.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cicatrix; Collagen Ty | 2012 |
Mitomycin C: a promising agent for the treatment of canine corneal scarring.
Topics: Actins; Animals; Apoptosis; Cicatrix; Corneal Diseases; Corneal Keratocytes; Dog Diseases; Dogs; Dos | 2011 |
Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model.
Topics: Alkylating Agents; Animals; Antibodies, Monoclonal, Humanized; Cicatrix; Conjunctiva; Disease Models | 2013 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2012 |
Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery.
Topics: Administration, Topical; Alkylating Agents; Animals; Cicatrix; Conjunctival Diseases; Disease Models | 2012 |
Prevention of ocular scarring post glaucoma filtration surgery using the inflammatory cell and platelet binding modulator saratin in a rabbit model.
Topics: Administration, Topical; Animals; Blood Platelets; Cicatrix; Disease Models, Animal; Eye; Fibrosis; | 2012 |
Velopharyngeal and choanal stenosis after radiotherapy for nasopharyngeal carcinoma.
Topics: Antibiotics, Antineoplastic; Carcinoma; Cicatrix; Constriction, Pathologic; Endoscopy; Female; Human | 2013 |
Quiescent keratocytes fail to repair MMC induced DNA damage leading to the long-term inhibition of myofibroblast differentiation and wound healing.
Topics: Actins; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cicatrix | 2012 |
Histological and ultrastructural features for proliferation inhibition by delivery of exogenous p27Kip1 to rabbit models after glaucoma filtration surgery.
Topics: Adenoviridae; Animals; Cell Proliferation; Cicatrix; Conjunctiva; Cyclin-Dependent Kinase Inhibitor | 2012 |
[Mitomycin C treatment for ocular cicatricial pemphigoid].
Topics: Cicatrix; Eye Diseases; Humans; Mitomycin; Pemphigoid, Bullous | 2003 |
Prophylactic use of mitomycin-C in the management of a buttonholed LASIK flap.
Topics: Adult; Antibiotics, Antineoplastic; Cicatrix; Female; Humans; Keratomileusis, Laser In Situ; Lasers, | 2003 |
Collagen secretion after photodynamic therapy versus scar-inducing anti-cancer modalities: an in vitro study.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cicatrix; Collagen; Dose-Response Relationship | 2002 |
Mitomycin-C in the postsurgical ear canal.
Topics: Adult; Aged; Cicatrix; Debridement; Ear Canal; Ear, Middle; Female; Follow-Up Studies; Granulation T | 2003 |
Superficial keratectomy with mitomycin-C for the treatment of Salzmann's nodules.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Cornea; Corneal Diseases; Female; Follow-Up Studies; Human | 2003 |
[A method for preventing recurrent scarring of the tympatic cavity in surgical treatment of patients with suppurative otitis media].
Topics: Antibiotics, Antineoplastic; Cicatrix; Humans; Mitomycin; Otitis Media, Suppurative; Otologic Surgic | 2003 |
Mitomycin C trabeculectomy in an eye with cicatricial conjunctiva following amniotic membrane transplantation.
Topics: Adult; Amnion; Antibiotics, Antineoplastic; Biological Dressings; Cicatrix; Conjunctival Diseases; G | 2003 |
Trabeculectomy and antimetabolites.
Topics: Antimetabolites; Cicatrix; Clinical Competence; Fluorouracil; Glaucoma; Humans; Mitomycin; Trabecule | 2004 |
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo | 2004 |
Topical application of mitomycin C prevents epineural scar formation in rats.
Topics: Administration, Topical; Animals; Cicatrix; Dissection; Fibrosis; Male; Mitomycin; Nucleic Acid Synt | 2005 |
Effect of intraurethral Mitomycin-C on healing and fibrosis in rats with experimentally induced urethral stricture.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Disease Models, Animal; Dose-Response Relationship, | 2004 |
Deep sclerectomy augmented with mitomycin C.
Topics: Aged; Antihypertensive Agents; Blister; Cicatrix; Conjunctiva; Epidemiologic Methods; Exudates and T | 2005 |
Intraoperative mitomycin C and amniotic membrane transplantation for fornix reconstruction in severe cicatricial ocular surface diseases.
Topics: Adolescent; Adult; Aged; Amnion; Antibiotics, Antineoplastic; Child; Child, Preschool; Cicatrix; Com | 2005 |
Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery.
Topics: Animals; Antibiotics, Antineoplastic; Cicatrix; Conjunctiva; Disease Models, Animal; Enzyme Inhibito | 2005 |
Mitomycin-C assisted photorefractive keratectomy in the treatment of buttonholed laser in situ keratomileusis flaps associated with epithelial ingrowth.
Topics: Adult; Anti-Bacterial Agents; Cicatrix; Cornea; Corneal Diseases; Corneal Surgery, Laser; Drug Thera | 2005 |
Effect of topical mitomycin C on the healing of surgical and laser wounds: a hint on clinical application.
Topics: Administration, Topical; Animals; Cell Proliferation; Cicatrix; Dermatologic Surgical Procedures; Di | 2005 |
Effect of topical mitomycin C for antrostomy in rabbit with sinusitis.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Cicatrix; Disease Models, Animal; Mal | 2006 |
[Dosage and kinetics of MMC release of a collagen implant used as a delivery device in glaucoma surgery in the rabbit eye].
Topics: Animals; Cicatrix; Collagen; Drug Delivery Systems; Filtering Surgery; Glaucoma; Mitomycin; Prosthes | 2006 |
Benefits and risks of mitomycin use in the traumatized tracheal mucosa.
Topics: Airway Obstruction; Animals; Antibiotics, Antineoplastic; Cause of Death; Cicatrix; Disease Models, | 2007 |
Antiproliferative agents and the prevention of scarring after surgery: friend or foe?
Topics: Cicatrix; Filtering Surgery; Glaucoma; Humans; Mitomycin | 1995 |
Effect of varying the mitomycin-C treatment area in glaucoma filtration surgery in the rabbit.
Topics: Animals; Cicatrix; Conjunctiva; Eye; Filtering Surgery; Glaucoma; Injections; Mitomycin; Rabbits; Wo | 1997 |
Mitomycin C reduces scar formation after excimer laser (193 nm) photorefractive keratectomy in rabbits.
Topics: Animals; Cell Count; Cicatrix; Cornea; Female; Lasers, Excimer; Light; Mitomycin; Nucleic Acid Synth | 1997 |
Mitomycin-C in the treatment of tracheal cicatrix after tracheal reconstruction.
Topics: Administration, Topical; Adolescent; Child; Child, Preschool; Cicatrix; Female; Humans; Male; Mitomy | 1998 |
Mitomycin C trabeculectomy in eyes with cicatricial conjunctiva.
Topics: Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Cicatrix; Conjunctival Diseases; Follow-Up S | 1998 |
[The effect of heterogeneous scleral transplantation on hypotony after filtration surgery of glaucoma with mitomycin C].
Topics: Adolescent; Adult; Cicatrix; Female; Filtering Surgery; Follow-Up Studies; Glaucoma; Humans; Male; M | 1997 |
Transforming growth factor-beta1, -beta2, and -beta3 in vivo: effects on normal and mitomycin C-modulated conjunctival scarring.
Topics: Animals; Cicatrix; Collagen; Conjunctiva; Conjunctival Diseases; Elastic Tissue; Fluorescent Antibod | 1999 |
[A preliminary report of antiscar formation effect by subconjunctival injection of mitomycin C before trabeculectomy in glaucoma].
Topics: Adult; Aged; Alkylating Agents; Cicatrix; Female; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Hum | 1998 |
Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery.
Topics: Administration, Topical; Animals; Antimetabolites; Cicatrix; Conjunctiva; Fluorouracil; Intraoperati | 1997 |
Histologic effect of mitomycin C on strabismus surgery in the rabbit.
Topics: Animals; Antimetabolites; Cicatrix; Granuloma; Intraoperative Care; Mitomycin; Oculomotor Muscles; P | 2000 |
Mitomycin C reduces corneal light scattering after excimer keratectomy.
Topics: Alkylating Agents; Animals; Cicatrix; Cornea; Corneal Diseases; Drug Evaluation, Preclinical; Intrao | 2001 |
Mitomycin C in sinus surgery: preliminary results in a rabbit model.
Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Cicatrix; Male; Maxillary Sinus; Mito | 2001 |
The effects of subconjunctival mitomycin-C on glaucoma filtration surgery in rabbits.
Topics: Administration, Topical; Animals; Cicatrix; Combined Modality Therapy; Glaucoma; Intraocular Pressur | 1991 |