mitomycin has been researched along with Chronic Illness in 37 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Excerpt | Relevance | Reference |
---|---|---|
"To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation." | 7.71 | Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001) |
"To investigate the participation of endothelial cells in glomerulosclerosis, the study was performed in serum sickness nephritis (SSN) with administration of mitomycin C (MMC)." | 7.69 | Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C. ( Chowdhury, AK, 1996) |
"Erythropoietin may be lowered by cancer itself or because of chemoradiotherapy." | 6.76 | Chronic anemia due to mitomycin C is drug dose-dependent, normocytic, progressive, related to erythropoietin levels and quantitatively predictable: implications for radiochemotherapy. ( Cartei, F; Cartei, G; Colombrino, E; Fiorica, F; Giraldi, T; Micucci, M; Plebani, M; Sanzari, MC; Zustovich, F, 2011) |
"To compare phacoemulsification versus trabeculectomy with adjunctive mitomycin C in medically uncontrolled chronic angle-closure glaucoma (CACG) without cataract." | 5.17 | Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract. ( Baig, N; Kwong, YY; Lam, DS; Leung, DY; Li, FC; Tham, CC, 2013) |
"Combined phacotrabeculectomy with adjunctive mitomycin C is more effective than phacoemulsification alone in controlling IOP in medically uncontrolled CACG eyes with coexisting cataract." | 5.14 | Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts. ( Chan, JC; Chiu, TY; Kwong, YY; Lai, JS; Lam, DS; Lam, SW; Leung, DY; Li, FC; Tham, CC, 2009) |
"Combined phacotrabeculectomy with adjunctive mitomycin C may be marginally more effective than phacoemulsification alone in controlling IOP in medically controlled CACG eyes with coexisting cataract." | 5.13 | Phacoemulsification versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma with cataract. ( Chan, CH; Chan, JC; Chi, CC; Chiu, TY; Kwong, YY; Lai, JS; Lam, DS; Lam, SW; Leung, DY; Li, FC; Poon, AS; Tham, CC; Yick, DW, 2008) |
"To compare the intraocular pressure (IOP)-lowering effect of combined viscocanalostomy and phacoemulsification and combined trabeculectomy and phacoemulsification with mitomycin C in eyes with primary open-angle glaucoma." | 5.12 | Randomized comparison of the intraocular pressure-lowering effect of phacoviscocanalostomy and phacotrabeculectomy. ( Kobayashi, H; Kobayashi, K, 2007) |
"In the diclofenac group (n = 14), the preoperative intraocular pressure of 30." | 5.08 | The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. ( Cate, EA; Dubiner, HB; Kent, AR; Mundorf, TK; Stewart, JA; Stewart, WC; Whitaker, R, 1998) |
"To report a new approach for the treatment of severe ocular hypotony secondary to glaucoma filtering surgery with mitomycin C by injecting autologous eye platelet-rich plasma (E-PRP) in the anterior chamber to block excessive diffuse filtration through an abnormally thinned sclera." | 3.91 | Treatment of chronic and extreme ocular hypotension following glaucoma surgery with intraocular platelet-rich plasma: A case report. ( Abdalrahman, O; Alio Del Barrio, JL; Alio, JL; Rodriguez, AE, 2019) |
"Mitomycin C was applied in the median frontal drainage pathway of a 44-year-old woman suffering from recalcitrant chronic frontal sinusitis." | 3.77 | Safe application of mitomycin C within the nasal cavity. ( Gutierrez, T; Hopkins, C, 2011) |
" In this study, we examined the effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (THSG), an active component extracted from Polygonum multiflorum Thunb, on acetic acid-induced acute colitis and mitomycin C-induced chronic colitis." | 3.74 | Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. ( Chen, S; Han, T; Wang, J; Wang, X; Zhao, L, 2008) |
"Only by additional partial excision of the handle of malleus followed by local application of mitomycin were we able to achieve a persistent tympanic membrane perforation." | 3.72 | [An improved animal model for chronic perforation of the tympanic membrane]. ( Beule, A; Hosemann, W; Junghans, D; Kaftan, H, 2004) |
"To determine the ability of topically applied mitomycin C to create a stable tympanic membrane perforation." | 3.71 | Creating a stable tympanic membrane perforation using mitomycin C. ( Cass, SP; Goldman, SA; O'Reilly, RC; Widner, SA, 2001) |
"Retrospective analysis of all eyes that underwent phacoemulsification surgery for symptomatic cataracts and had a preoperative diagnosis of chronic hypotony (intraocular pressure [IOP] =6 mm Hg) for at least 6 months following trabeculectomy with mitomycin C." | 3.70 | Effect of phacoemulsification surgery on hypotony following trabeculectomy surgery. ( Doyle, JW; Smith, MF, 2000) |
"To investigate the participation of endothelial cells in glomerulosclerosis, the study was performed in serum sickness nephritis (SSN) with administration of mitomycin C (MMC)." | 3.69 | Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C. ( Chowdhury, AK, 1996) |
"In this pilot study with a small number of subjects, short-term outcomes suggest that subconjunctival bevacizumab is equally effective in reducing intraocular pressure with a better safety profile compared with MMC in the dosing schedule studied." | 2.77 | Safety and efficacy of using off-label bevacizumab versus mitomycin C to prevent bleb failure in a single-site phacotrabeculectomy by a randomized controlled clinical trial. ( Ravindran, RD; Sengupta, S; Venkatesh, R, 2012) |
"Erythropoietin may be lowered by cancer itself or because of chemoradiotherapy." | 2.76 | Chronic anemia due to mitomycin C is drug dose-dependent, normocytic, progressive, related to erythropoietin levels and quantitatively predictable: implications for radiochemotherapy. ( Cartei, F; Cartei, G; Colombrino, E; Fiorica, F; Giraldi, T; Micucci, M; Plebani, M; Sanzari, MC; Zustovich, F, 2011) |
"Mitomycin C (MMC) is an antibiotic-antineoplastic agent that decreases fibroblast proliferation and scar formation." | 2.72 | Effect of mitomycin C on the size of antrostomy after endoscopic sinus surgery. ( Cha, HE; Chung, YS; Gang, IG; Ha, JS; Kim, ST, 2006) |
"Choroidal detachment is a major postoperative complication of trabeculectomy." | 1.56 | Chronic chorioretinal detachment under normal intraocular pressure in eye with uveitic glaucoma after trabeculectomy: A case report. ( Abe, T; Sakurai, Y; Takayama, K; Takeuchi, M, 2020) |
"Mitomycin C 0." | 1.38 | Regional conjunctivectomy with postoperative mitomycin C to treat chronic hyperemic conjunctiva. ( Kim, BH, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (5.41) | 18.7374 |
1990's | 4 (10.81) | 18.2507 |
2000's | 13 (35.14) | 29.6817 |
2010's | 16 (43.24) | 24.3611 |
2020's | 2 (5.41) | 2.80 |
Authors | Studies |
---|---|
Janetka, JW | 1 |
Hopper, AT | 1 |
Yang, Z | 1 |
Barks, J | 1 |
Dhason, MS | 1 |
Wang, Q | 1 |
Sibley, LD | 1 |
Sakurai, Y | 1 |
Takayama, K | 1 |
Abe, T | 1 |
Takeuchi, M | 1 |
Abdalrahman, O | 1 |
Rodriguez, AE | 1 |
Alio Del Barrio, JL | 1 |
Alio, JL | 1 |
Dean, WH | 1 |
Turner, SA | 1 |
McNaught, AI | 1 |
López, E | 1 |
Domenech, A | 1 |
Ferrándiz, MJ | 1 |
Frias, MJ | 1 |
Ardanuy, C | 1 |
Ramirez, M | 1 |
García, E | 1 |
Liñares, J | 1 |
de la Campa, AG | 1 |
Konstantinidis, I | 1 |
Chatziavramidis, A | 1 |
Constantinidis, J | 1 |
Yun, ST | 1 |
Chua, B | 1 |
Clement, CI | 1 |
Wang, AY | 2 |
Shen, Y | 2 |
Liew, LJ | 2 |
Wang, JT | 2 |
von Unge, M | 2 |
Atlas, MD | 2 |
Dilley, RJ | 2 |
Tham, CC | 3 |
Kwong, YY | 3 |
Leung, DY | 3 |
Lam, SW | 2 |
Li, FC | 3 |
Chiu, TY | 2 |
Chan, JC | 2 |
Chan, CH | 1 |
Poon, AS | 1 |
Yick, DW | 1 |
Chi, CC | 1 |
Lam, DS | 3 |
Lai, JS | 2 |
Chung, J | 1 |
Connolly, B | 1 |
Langer, J | 1 |
Marcon, M | 1 |
Temple, M | 1 |
Amaral, JG | 1 |
Nazm, N | 1 |
Gandhi, M | 1 |
Dubey, S | 1 |
Pegu, J | 1 |
Iyer, JV | 1 |
Perera, SA | 1 |
Aung, T | 1 |
Gutierrez, T | 1 |
Hopkins, C | 1 |
Sengupta, S | 1 |
Venkatesh, R | 1 |
Ravindran, RD | 1 |
Baradaranfar, MH | 1 |
Khadem, J | 1 |
Taghipoor Zahir, S | 1 |
Kouhi, A | 1 |
Dadgarnia, MH | 1 |
Baradarnfar, A | 1 |
Kim, BH | 1 |
Venkatraman, V | 1 |
Balasubramanian, D | 1 |
Gopalakrishnan, S | 1 |
Saxena, SK | 1 |
Shanmugasundaram, N | 1 |
Cartei, G | 1 |
Colombrino, E | 1 |
Sanzari, MC | 1 |
Plebani, M | 1 |
Micucci, M | 1 |
Fiorica, F | 1 |
Giraldi, T | 1 |
Zustovich, F | 1 |
Cartei, F | 1 |
Baig, N | 1 |
Sa, Q | 1 |
Woodward, J | 1 |
Suzuki, Y | 1 |
Willoch, CM | 1 |
Nicolaissen, B | 1 |
Kaftan, H | 1 |
Hosemann, W | 1 |
Beule, A | 1 |
Junghans, D | 1 |
Kim, ST | 1 |
Gang, IG | 1 |
Cha, HE | 1 |
Ha, JS | 1 |
Chung, YS | 1 |
Kobayashi, H | 1 |
Kobayashi, K | 1 |
Wang, X | 1 |
Zhao, L | 1 |
Han, T | 1 |
Chen, S | 1 |
Wang, J | 1 |
Amar, N | 1 |
Labbé, A | 1 |
Hamard, P | 1 |
Dupas, B | 1 |
Baudouin, C | 1 |
Hyung, SM | 1 |
Choi, MY | 1 |
Kang, SW | 1 |
Kent, AR | 1 |
Dubiner, HB | 1 |
Whitaker, R | 1 |
Mundorf, TK | 1 |
Stewart, JA | 1 |
Cate, EA | 1 |
Stewart, WC | 1 |
Fischman, HK | 1 |
Kelly, DD | 1 |
Chowdhury, AK | 1 |
Doyle, JW | 1 |
Smith, MF | 1 |
O'Reilly, RC | 1 |
Goldman, SA | 1 |
Widner, SA | 1 |
Cass, SP | 1 |
Stamper, R | 1 |
Hetherington, JW | 1 |
Whelan, P | 1 |
Hostetter, AL | 1 |
Tubbs, RR | 1 |
Ziegler, T | 1 |
Gephardt, GN | 1 |
McMahon, JT | 1 |
Schreiber, MJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparison of Combined Phacotrabeculectomy and Trabeculectomy Only in the Treatment of Primary Angle-closure Glaucoma[NCT01298635] | 31 participants (Actual) | Interventional | 2005-01-31 | Completed | |||
Prospective Study on Ex-PRESS Implantation Combined With Phacoemulsification in Primary Angle-closure Glaucoma[NCT03323138] | 40 participants (Anticipated) | Interventional | 2012-07-01 | Recruiting | |||
Effectiveness and Safety of Trabeculectomy and Peripheral Iridectomy Plus Goniotomy in Advanced Primary Angle-closure Glaucoma: a Multicenter Non-inferiority Randomized Controlled Trial[NCT05163951] | 88 participants (Anticipated) | Interventional | 2022-01-05 | Recruiting | |||
Effectiveness and Safety of Phacotrabeculectomy and Phacogoniotomy in Advanced Primary Angle-closure Glaucoma: a Multicenter Randomized Controlled Trial[NCT04878458] | 124 participants (Actual) | Interventional | 2021-05-31 | Active, not recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
11 trials available for mitomycin and Chronic Illness
Article | Year |
---|---|
A novel technique for mitomycin-c application in frontal sinus surgery.
Topics: Administration, Topical; Adult; Aged; Chronic Disease; Cicatrix; Constriction, Pathologic; Cross-Ove | 2014 |
Phacoemulsification versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma with cataract.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Disease; Fema | 2008 |
Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Disease; Fema | 2009 |
Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Disease; Fema | 2009 |
Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Disease; Fema | 2009 |
Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Disease; Fema | 2009 |
Safety and efficacy of using off-label bevacizumab versus mitomycin C to prevent bleb failure in a single-site phacotrabeculectomy by a randomized controlled clinical trial.
Topics: Aged; Alkylating Agents; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Ca | 2012 |
Prevention of adhesion after endoscopic sinus surgery: role of mitomycin C.
Topics: Administration, Topical; Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Endoscopy; F | 2011 |
Topical Mitomycin C in functional endoscopic sinus surgery.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chronic Disease; Female; Humans; Male; | 2012 |
Chronic anemia due to mitomycin C is drug dose-dependent, normocytic, progressive, related to erythropoietin levels and quantitatively predictable: implications for radiochemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Agents; Chemoradiotherapy; Chronic Disease; D | 2011 |
Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Diseas | 2013 |
Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Diseas | 2013 |
Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Diseas | 2013 |
Phacoemulsification versus trabeculectomy in medically uncontrolled chronic angle-closure glaucoma without cataract.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antihypertensive Agents; Cataract; Chronic Diseas | 2013 |
Effect of mitomycin C on the size of antrostomy after endoscopic sinus surgery.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Chronic Disease; Cica | 2006 |
Randomized comparison of the intraocular pressure-lowering effect of phacoviscocanalostomy and phacotrabeculectomy.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Cataract; Catheterization; Chronic Disease; Female; Glau | 2007 |
The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Chr | 1998 |
26 other studies available for mitomycin and Chronic Illness
Article | Year |
---|---|
Optimizing Pyrazolopyrimidine Inhibitors of Calcium Dependent Protein Kinase 1 for Treatment of Acute and Chronic Toxoplasmosis.
Topics: Acute Disease; Animals; Binding Sites; Cell Line; Cell Proliferation; Chronic Disease; Crystallograp | 2020 |
Chronic chorioretinal detachment under normal intraocular pressure in eye with uveitic glaucoma after trabeculectomy: A case report.
Topics: Antibiotics, Antineoplastic; Choroidal Effusions; Chronic Disease; Glaucoma; Humans; Intraocular Pre | 2020 |
Treatment of chronic and extreme ocular hypotension following glaucoma surgery with intraocular platelet-rich plasma: A case report.
Topics: Alkylating Agents; Anterior Chamber; Chronic Disease; Filtering Surgery; Glaucoma; Humans; Intraocul | 2019 |
Secondary glaucoma due to chronic scleritis: trabeculectomy in scleromalacia: a case report.
Topics: Aged; Alkylating Agents; Chronic Disease; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; I | 2014 |
Induction of prophages by fluoroquinolones in Streptococcus pneumoniae: implications for emergence of resistance in genetically-related clones.
Topics: Blotting, Southern; Chronic Disease; Ciprofloxacin; Disease Progression; Drug Resistance, Bacterial; | 2014 |
Outcomes of chronic hypotony following trabeculectomy.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Chronic Disease; Female; Glaucoma; Humans; Intraocular P | 2015 |
Searching for a rat model of chronic tympanic membrane perforation: Healing delayed by mitomycin C/dexamethasone but not paper implantation or iterative myringotomy.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease Models | 2015 |
Rat model of chronic tympanic membrane perforation: Ventilation tube with mitomycin C and dexamethasone.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disease; Dexamethasone; Disease | 2016 |
Fluoroscopy-guided topical application of mitomycin-C in a case of refractory esophageal stricture.
Topics: Administration, Topical; Child, Preschool; Chronic Disease; Esophageal Stenosis; Female; Fluoroscopy | 2010 |
Angle closure glaucoma.
Topics: Antihypertensive Agents; Cataract; Chronic Disease; Glaucoma, Angle-Closure; Humans; Intraocular Pre | 2009 |
Phacoemulsification and glaucoma.
Topics: Antihypertensive Agents; Cataract; Chronic Disease; Glaucoma, Angle-Closure; Humans; Intraocular Pre | 2009 |
Safe application of mitomycin C within the nasal cavity.
Topics: Administration, Topical; Adult; Antibiotics, Antineoplastic; Chronic Disease; Cicatrix; Drug Deliver | 2011 |
Regional conjunctivectomy with postoperative mitomycin C to treat chronic hyperemic conjunctiva.
Topics: Adult; Aged; Astringents; Chronic Disease; Conjunctiva; Female; Follow-Up Studies; Humans; Hyperemia | 2012 |
IL-2 produced by CD8+ immune T cells can augment their IFN-γ production independently from their proliferation in the secondary response to an intracellular pathogen.
Topics: Animals; Antibodies; Antigens, Protozoan; CD8-Positive T-Lymphocytes; Cell Proliferation; Chronic Di | 2013 |
Amnion-shielded trabeculectomy.
Topics: Amnion; Aqueous Humor; Biological Dressings; Chronic Disease; Glaucoma; Humans; Intraocular Pressure | 2003 |
[An improved animal model for chronic perforation of the tympanic membrane].
Topics: Administration, Topical; Animals; Chronic Disease; Disease Models, Animal; Male; Microsurgery; Mitom | 2004 |
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice.
Topics: Acetic Acid; Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chronic Disease; Coliti | 2008 |
Filtering blebs and aqueous pathway an immunocytological and in vivo confocal microscopy study.
Topics: Aged; Aged, 80 and over; Antimetabolites; Aqueous Humor; Cell Count; Chronic Disease; Conjunctiva; E | 2008 |
Management of chronic hypotony following trabeculectomy with mitomycin C.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Blood; Chronic Disease; Follow-Up Studies; Gla | 1997 |
Chromosomes and stress.
Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; Chronic Disease; Conditioning, Psychological; El | 1999 |
Participation of endothelial cells in the development of glomerulosclerosis: a study on murine serum sickness nephritis with mitomycin C.
Topics: Animals; Basement Membrane; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Extracel | 1996 |
Effect of phacoemulsification surgery on hypotony following trabeculectomy surgery.
Topics: Aged; Aged, 80 and over; Cataract; Chemotherapy, Adjuvant; Chronic Disease; Female; Glaucoma; Humans | 2000 |
Creating a stable tympanic membrane perforation using mitomycin C.
Topics: Alkylating Agents; Animals; Chronic Disease; Disease Models, Animal; Male; Middle Ear Ventilation; M | 2001 |
Bilateral chronic hypotony following trabeculectomy with mitomycin-C.
Topics: Adult; Age Factors; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Mit | 2001 |
Persistent ulcers after bladder instillation of mitomycin C.
Topics: Chronic Disease; Humans; Mitomycin; Mitomycins; Neoplasm Recurrence, Local; Neoplasms, Multiple Prim | 1986 |
Chronic glomerular microangiopathy complicating metastatic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Anemia, Hemolytic; Blood Coagulation; Chronic Disease; Female; Hemolyti | 1987 |