Page last updated: 2024-11-06

mitomycin and Chromosome Deletion

mitomycin has been researched along with Chromosome Deletion in 14 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Chromosome Deletion: Actual loss of portion of a chromosome.

Research Excerpts

ExcerptRelevanceReference
"Analysis of chromosome breakage with mitomycin C (MMC) and folate-deficient culture conditions was undertaken on 18 Prader-Labhart-Willi syndrome (PLWS) patients (10 with 15q12 deletion [5 females, 5 males; mean age = 17."3.67Analysis of chromosome breakage in the Prader-Labhart-Willi syndrome. ( Butler, MG; Jenkins, BB, 1989)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's6 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huffman, GA1
Rownd, RH1
Cunha, KS1
Reguly, ML2
Gimmler-Luz, MC2
Santos, JH2
Lehmann, M2
de Andrade, HH2
Eickelmann, P1
Schulz, WA1
Rohde, D1
Schmitz-Dräger, B1
Sies, H1
Honma, M1
Hayashi, M1
Sofuni, T1
Correa, MJ1
Kalman, M1
Murphy, H1
Cashel, M1
Levy, MS1
Pomposiello, P1
Nagel, R1
Albertini, S1
Friederich, U1
Würgler, FE1
Butler, MG1
Jenkins, BB1
Inoue, H1
Schroeder, AL1
Yandell, DW1
Dryja, TP1
Little, JB1
Melaragno, MI1
Ribeiro, MC1
Smith, Mde A1
Andrade, JA1
Erwenne, CM1
Lloyd, RG1
Buckman, C1
Lampe, MF1
Bott, KF1

Other Studies

14 other studies available for mitomycin and Chromosome Deletion

ArticleYear
Transition of deletion mutants of the composite resistance plasmid NR1 in Escherichia coli and Salmonella typhimurium.
    Journal of bacteriology, 1984, Volume: 159, Issue:2

    Topics: Anti-Bacterial Agents; Base Sequence; Chromosome Deletion; DNA Restriction Enzymes; Escherichia coli

1984
Co-mutagenic effect of tannic acid on ring-X chromosome loss induced by mitomycin C in sperm cells of Drosophila melanogaster.
    Mutation research, 1994, Jul-16, Volume: 308, Issue:2

    Topics: Animals; Antimutagenic Agents; Chi-Square Distribution; Chromosome Deletion; DNA Repair; Drosophila

1994
Loss of heterozygosity at the NAD(P)H: quinone oxidoreductase locus associated with increased resistance against mitomycin C in a human bladder carcinoma cell line.
    Biological chemistry Hoppe-Seyler, 1994, Volume: 375, Issue:7

    Topics: Base Sequence; Cell Division; Chromosome Deletion; DNA Primers; Drug Resistance; Heterozygote; Human

1994
Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells.
    Mutation research, 1997, Mar-04, Volume: 374, Issue:1

    Topics: Cell Line; Chromosome Breakage; Chromosome Deletion; DNA Fingerprinting; Ethyl Methanesulfonate; Gen

1997
Suppressing effect of vanillin on chromosome aberrations that occur spontaneously or are induced by mitomycin C in the germ cell line of Drosophila melanogaster.
    Mutation research, 1992, Jun-16, Volume: 279, Issue:4

    Topics: Animals; Antimutagenic Agents; Benzaldehydes; Chi-Square Distribution; Chromosome Deletion; DNA Repa

1992
The nucleotide sequence of recG, the distal spo operon gene in Escherichia coli K-12.
    Gene, 1992, Jan-02, Volume: 110, Issue:1

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Chromosome Deletion; Cloning, Molecular; Esc

1992
RecA-dependent increased precise excision of Tn10 in Salmonella typhimurium.
    Mutation research, 1991, Volume: 255, Issue:1

    Topics: Chromosome Deletion; DNA Repair; DNA Transposable Elements; Mitomycin; Mitomycins; Mutation; Rec A R

1991
Reversible inhibition of mammalian tubulin assembly in vitro and effects in Saccharomyces cerevisiae D61.M by mitomycin C.
    Mutagenesis, 1989, Volume: 4, Issue:1

    Topics: Animals; Brain Chemistry; Cell Survival; Chromosome Deletion; Cycloheximide; Diploidy; Dithioerythri

1989
Analysis of chromosome breakage in the Prader-Labhart-Willi syndrome.
    American journal of medical genetics, 1989, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Deletion; Chromosome Fragile

1989
A new mutagen-sensitive mutant in Neurospora, mus-16.
    Mutation research, 1988, Volume: 194, Issue:1

    Topics: Chromosome Deletion; DNA Repair; DNA, Fungal; Genes, Fungal; Mechlorethamine; Mitomycin; Mitomycins;

1988
Somatic mutations at a heterozygous autosomal locus in human cells occur more frequently by allele loss than by intragenic structural alterations.
    Somatic cell and molecular genetics, 1986, Volume: 12, Issue:3

    Topics: B-Lymphocytes; Base Sequence; Cell Line; Chromosome Deletion; DNA Restriction Enzymes; Humans; Mitom

1986
Sister chromatid exchange frequency in a retinoblastoma mosaic patient with del(13).
    Cancer genetics and cytogenetics, 1988, Volume: 32, Issue:2

    Topics: Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 13; Eye Neoplasms; Humans; Male; Mit

1988
Identification and genetic analysis of sbcC mutations in commonly used recBC sbcB strains of Escherichia coli K-12.
    Journal of bacteriology, 1985, Volume: 164, Issue:2

    Topics: Chromosome Deletion; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Conjugation, Ge

1985
Cloning of the Bacillus subtilis recF gene.
    Gene, 1985, Volume: 38, Issue:1-3

    Topics: Bacillus subtilis; Bacterial Proteins; Chromosome Deletion; Chromosome Mapping; Cloning, Molecular;

1985