Page last updated: 2024-11-06

mitomycin and Cholestasis

mitomycin has been researched along with Cholestasis in 9 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"We describe a case of hepatoma, a 66-year-old woman, presenting with obstructive jaundice, whom we treated with intra-arterial infusion of the anticancer drug, MMC."1.29[A case of icteric type hepatoma responding to MMC infusion therapy via cannulation into the hepatic artery]. ( Kato, S; Kobayashi, H; Nakagawa, T, 1993)
"Excisions of metastatic liver cancer were performed in 36 patients and 23 had nonresectable metastatic liver cancer."1.28[Complications of intra-arterial infusion chemotherapy in patients with colorectal cancer with liver metastasis, with special reference to IA-5-FU induced sclerosing cholangitis]. ( Hojo, K; Moriya, Y; Sawada, T, 1989)
" Infusion time, cholestasis, and urinary pH did not influence the pharmacokinetic data."1.27Relationship between clinical parameters and pharmacokinetics of mitomycin C. ( de Vries, J; den Hartigh, J; Pinedo, HM; Stuurman, M; Verweij, J, 1987)
"Excisions of metastatic liver cancer were performed in 23 pts and 15 pts had nonresectable metastatic liver cancer."1.27[Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer]. ( Hojo, K; Moriya, Y; Sawada, T, 1988)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, JS1
Jeong, S1
Lee, DH1
Yamaguchi, K1
Miyashita, K1
Aizawa, K1
Todoroki, H1
Kiyonaga, H1
Kato, S1
Kobayashi, H1
Nakagawa, T1
Ishikawa, A1
Matsuura, M1
Nakajima, N1
Ozawa, M1
Matsuda, M1
Ito, K1
Suzuki, K1
Toyama, K1
Nonaka, M1
Oosawa, J1
Nakanishi, M1
Kamiyama, J1
Idoguchi, K1
Tabata, T1
Okuno, T1
Itoshima, T1
Sawada, T2
Hojo, K2
Moriya, Y2
Verweij, J1
den Hartigh, J1
Stuurman, M1
de Vries, J1
Pinedo, HM1
Shioda, Y1
Koizumi, S1
Furuya, S1
Tokunaga, A1
Tanaka, N1
Onda, M1

Other Studies

9 other studies available for mitomycin and Cholestasis

ArticleYear
Effects of mitomycin-eluting metal stents on benign biliary stricture in a swine model: A feasibility study.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2018, Volume: 30, Issue:6

    Topics: Animals; Cholestasis; Disease Models, Animal; Drug-Eluting Stents; Feasibility Studies; Mitomycin; N

2018
[A case of gastric cancer with liver metastasis in which obstruction of the bile duct and choledocholithiasis was caused by intra-hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:4

    Topics: Angiotensin II; Cholestasis; Drug Administration Schedule; Drug Therapy, Combination; Gallstones; Ga

2003
[A case of icteric type hepatoma responding to MMC infusion therapy via cannulation into the hepatic artery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:14

    Topics: Aged; Carcinoma, Hepatocellular; Cholestasis; Female; Humans; Infusions, Intra-Arterial; Liver Neopl

1993
[Advanced breast cancer with onset of multi-organ metastases successfully treated with combined loco-regional therapies: a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Ch

1993
[A case of gastric cancer with peritoneal dissemination and malignant biliary stenosis treated by loco-regional cancer therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Cisplatin; Combined Modality Ther

1996
[Complications of intra-arterial infusion chemotherapy in patients with colorectal cancer with liver metastasis, with special reference to IA-5-FU induced sclerosing cholangitis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cholangitis, Sclerosin

1989
Relationship between clinical parameters and pharmacokinetics of mitomycin C.
    Journal of cancer research and clinical oncology, 1987, Volume: 113, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Female; Humans; Kidney; Ma

1987
[Two cases of obstructive jaundice due to advanced gastric cancer with marked response to the intravenous administration of cisplatinum].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Cisplatin; Female

1988
[Results of intra-arterial infusion chemotherapy in colorectal cancer patients with metastatic liver cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cholestasis; Colonic Neoplasms; Combined Modality Th

1988