mitomycin has been researched along with Cholangiocarcinoma in 23 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed the effect of purified green tea catechins on chemotherapy-induced apoptosis in KMCH, CC-LP-1 and Mz-ChA-1 human cholangiocarcinoma cells, and on chemosensitivity of Mz-ChA-1 cell xenografts in nude mice." | 7.75 | Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. ( Braconi, C; Henson, R; Lang, M; Patel, T, 2009) |
| " Then cholangiocarcinoma cells were induced to apoptosis with mitomycin." | 7.72 | [Immune response of dendritic cells acquiring antigens from apoptotic cholangiocarcinoma cells induced by mitomycin]. ( Han, BL; Pei, XT; Wu, G, 2003) |
| "Unresectable intrahepatic cholangiocarcinoma has a poor prognosis, with a median survival of 5 to 8 months without treatment." | 5.37 | Chemoembolization of intrahepatic cholangiocarcinoma with cisplatinum, doxorubicin, mitomycin C, ethiodol, and polyvinyl alcohol: a 2-center study. ( Albert, M; Christians, K; Fraker, D; Kiefer, MV; McNally, M; Olthoff, K; Pappas, S; Rilling, W; Robertson, M; Soulen, MC; Sun, W, 2011) |
| "Cholangiocarcinomas are devastating cancers that are resistant to chemotherapies." | 5.36 | Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents. ( DeMorrow, S; Frampton, GA; Lazcano, EA; Li, H; Mohamad, A, 2010) |
| "We have reported a 33% partial response rate with acceptable toxicity using weekly 24-h infusion of high-dose 5-fluorouracil (5-FU) and leucovorin (LV) in patients with far advanced biliary tract cancers (BTC)." | 5.09 | Mitomycin C with weekly 24-h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract and periampullar carcinomas. ( Chen, JS; Jan, YY; Liau, CT; Lin, YC, 2001) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "We assessed the effect of purified green tea catechins on chemotherapy-induced apoptosis in KMCH, CC-LP-1 and Mz-ChA-1 human cholangiocarcinoma cells, and on chemosensitivity of Mz-ChA-1 cell xenografts in nude mice." | 3.75 | Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells. ( Braconi, C; Henson, R; Lang, M; Patel, T, 2009) |
| " Then cholangiocarcinoma cells were induced to apoptosis with mitomycin." | 3.72 | [Immune response of dendritic cells acquiring antigens from apoptotic cholangiocarcinoma cells induced by mitomycin]. ( Han, BL; Pei, XT; Wu, G, 2003) |
| "Mitomycin C (MMC) in combination with infusional 5-fluorouracil (FU) plus folinic acid (FA) is an effective treatment for metastatic gastrointestinal cancer." | 2.71 | Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer. ( Gnad, U; Hartmann, JT; Hehlmann, R; Hochhaus, A; Hofheinz, RD; Kreil, S; Saussele, S; Weisser, A; Willer, A, 2004) |
| "They include intrahepatic and extrahepatic cholangiocarcinomas, gallbladder carcinomas, and ampullary carcinomas." | 2.58 | Gemcitabine-based chemotherapy for advanced biliary tract carcinomas. ( Abdel-Rahman, O; Elhalawani, H; Elsayed, Z, 2018) |
| " Nausea and vomiting occurred as adverse event (AE) in eight out of 25 treatments (32%), with seven of eight events (87." | 1.46 | Degradable Starch Microspheres Transcatheter Arterial Chemoembolization (DSM-TACE) in Intrahepatic Cholangiocellular Carcinoma (ICC): Results from a National Multi-Center Study on Safety and Efficacy. ( Albrecht, T; Michalik, K; Nolte-Ernsting, C; Pereira, PL; Pützler, M; Schicho, A; Stroszczynski, C; Wiggermann, P, 2017) |
| "Unresectable intrahepatic cholangiocarcinoma has a poor prognosis, with a median survival of 5 to 8 months without treatment." | 1.37 | Chemoembolization of intrahepatic cholangiocarcinoma with cisplatinum, doxorubicin, mitomycin C, ethiodol, and polyvinyl alcohol: a 2-center study. ( Albert, M; Christians, K; Fraker, D; Kiefer, MV; McNally, M; Olthoff, K; Pappas, S; Rilling, W; Robertson, M; Soulen, MC; Sun, W, 2011) |
| "Cholangiocarcinomas are devastating cancers that are resistant to chemotherapies." | 1.36 | Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents. ( DeMorrow, S; Frampton, GA; Lazcano, EA; Li, H; Mohamad, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 14 (60.87) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Rahman, O | 1 |
| Elsayed, Z | 1 |
| Elhalawani, H | 1 |
| Thorgersen, EB | 1 |
| Melum, E | 1 |
| Folseraas, T | 1 |
| Larsen, SG | 1 |
| Line, PD | 1 |
| Miyata, T | 1 |
| Beppu, T | 1 |
| Imamura, YU | 1 |
| Hayashi, H | 1 |
| Imai, K | 1 |
| Chikamoto, A | 1 |
| Yamashita, YI | 1 |
| Fukubayashi, K | 1 |
| Ishiko, T | 1 |
| Baba, H | 1 |
| Wirasorn, K | 1 |
| Ngamprasertchai, T | 1 |
| Khuntikeo, N | 1 |
| Pakkhem, A | 1 |
| Ungarereevittaya, P | 1 |
| Chindaprasirt, J | 1 |
| Sookprasert, A | 1 |
| Patkowski, W | 1 |
| Stankiewicz, R | 1 |
| Grąt, M | 1 |
| Krasnodębski, M | 1 |
| Kornasiewicz, O | 1 |
| Krawczyk, M | 1 |
| Huang, GL | 1 |
| Shen, DY | 1 |
| Cai, CF | 1 |
| Zhang, QY | 1 |
| Ren, HY | 1 |
| Chen, QX | 1 |
| Konstantinidis, IT | 1 |
| Groot Koerkamp, B | 1 |
| Do, RK | 1 |
| Gönen, M | 1 |
| Fong, Y | 1 |
| Allen, PJ | 1 |
| D'Angelica, MI | 1 |
| Kingham, TP | 1 |
| DeMatteo, RP | 1 |
| Klimstra, DS | 1 |
| Kemeny, NE | 1 |
| Jarnagin, WR | 1 |
| Schicho, A | 1 |
| Pereira, PL | 1 |
| Pützler, M | 1 |
| Michalik, K | 1 |
| Albrecht, T | 1 |
| Nolte-Ernsting, C | 1 |
| Stroszczynski, C | 1 |
| Wiggermann, P | 1 |
| Lang, M | 1 |
| Henson, R | 2 |
| Braconi, C | 1 |
| Patel, T | 2 |
| Liu, ZH | 2 |
| He, YP | 2 |
| Zhou, Y | 1 |
| Zhang, P | 2 |
| Qin, H | 2 |
| Frampton, GA | 1 |
| Lazcano, EA | 1 |
| Li, H | 1 |
| Mohamad, A | 1 |
| DeMorrow, S | 1 |
| Ma, YL | 1 |
| Zhou, YK | 1 |
| Kiefer, MV | 1 |
| Albert, M | 1 |
| McNally, M | 1 |
| Robertson, M | 1 |
| Sun, W | 1 |
| Fraker, D | 1 |
| Olthoff, K | 1 |
| Christians, K | 1 |
| Pappas, S | 1 |
| Rilling, W | 1 |
| Soulen, MC | 1 |
| Vogl, TJ | 2 |
| Naguib, NN | 1 |
| Nour-Eldin, NE | 1 |
| Bechstein, WO | 1 |
| Zeuzem, S | 1 |
| Trojan, J | 1 |
| Gruber-Rouh, T | 1 |
| Kuhlmann, JB | 1 |
| Euringer, W | 1 |
| Spangenberg, HC | 1 |
| Breidert, M | 1 |
| Blum, HE | 1 |
| Harder, J | 1 |
| Fischer, R | 1 |
| Wu, G | 1 |
| Han, BL | 1 |
| Pei, XT | 1 |
| Hofheinz, RD | 1 |
| Willer, A | 1 |
| Weisser, A | 1 |
| Gnad, U | 1 |
| Saussele, S | 1 |
| Kreil, S | 1 |
| Hartmann, JT | 1 |
| Hehlmann, R | 1 |
| Hochhaus, A | 1 |
| Naus, PJ | 1 |
| Bleeker, G | 1 |
| Wehbe, H | 1 |
| Meng, F | 1 |
| Zangos, S | 1 |
| Eichler, K | 1 |
| Selby, JB | 1 |
| Bauer, RW | 1 |
| Shitara, K | 1 |
| Ikami, I | 1 |
| Munakata, M | 1 |
| Muto, O | 1 |
| Sakata, Y | 1 |
| Niinobu, T | 1 |
| Shibata, T | 1 |
| Fukushima, Y | 1 |
| Kitada, M | 1 |
| Tukahara, Y | 1 |
| Hata, S | 1 |
| Ikeda, K | 1 |
| Hayashida, H | 1 |
| Fuzita, J | 1 |
| Takahashi, Y | 1 |
| Nakamura, T | 1 |
| Suzuki, R | 1 |
| Shimano, T | 1 |
| Takami, M | 1 |
| Ishida, T | 1 |
| Chen, JS | 1 |
| Lin, YC | 1 |
| Jan, YY | 1 |
| Liau, CT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PD-1 Antibody Plus Gemcitabine and Oxaliplatin (GEMOX) as Postoperative Adjuvant Therapy in Perihilar Cholangiocarcinoma Patients With Positively Metastatic Lymph Nodes : a Single Arm, Phase II Trial[NCT05430698] | Phase 2 | 62 participants (Anticipated) | Interventional | 2023-01-31 | Recruiting | ||
| A Phase II Trial of Induction Gemcitabine, Cisplatin and Nab-Paclitaxel Triplet Chemotherapy Followed by Gemcitabine, Cisplatin and Radioembolization for the Treatment of Locally Advanced Unresectable Intrahepatic Cholangiocarcinoma[NCT05422690] | Phase 2 | 16 participants (Anticipated) | Interventional | 2024-01-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mitomycin and Cholangiocarcinoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Gemcitabine-based chemotherapy for advanced biliary tract carcinomas.
Topics: Ampulla of Vater; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; B | 2018 |
4 trials available for mitomycin and Cholangiocarcinoma
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Treatment of unresectable cholangiocarcinoma: conventional transarterial chemoembolization compared with drug eluting bead-transarterial chemoembolization and systemic chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bile | 2012 |
Pegylated liposomal doxorubicin in combination with mitomycin C, infusional 5-fluorouracil and sodium folinic acid. A phase-I-study in patients with upper gastrointestinal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholangiocarcinoma; Dox | 2004 |
Mitomycin C with weekly 24-h infusion of high-dose 5-fluorouracil and leucovorin in patients with biliary tract and periampullar carcinomas.
Topics: Adenocarcinoma; Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Bilia | 2001 |
18 other studies available for mitomycin and Cholangiocarcinoma
| Article | Year |
|---|---|
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report.
Topics: Antineoplastic Agents, Alkylating; Bile Duct Neoplasms; Cholangiocarcinoma; Cholangitis, Sclerosing; | 2018 |
A 12-year Recurrence-free Survival After Multidisciplinary Treatment for a Patient With Combined Hepatocellular-Cholangiocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Chol | 2019 |
Adjuvant chemotherapy in resectable cholangiocarcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; | 2013 |
Poor outcomes after liver transplantation in patients with incidental cholangiocarcinoma irrespective of tumor localization.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic | 2014 |
β-escin reverses multidrug resistance through inhibition of the GSK3β/β-catenin pathway in cholangiocarcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; beta | 2015 |
Unresectable intrahepatic cholangiocarcinoma: Systemic plus hepatic arterial infusion chemotherapy is associated with longer survival in comparison with systemic chemotherapy alone.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; | 2016 |
Degradable Starch Microspheres Transcatheter Arterial Chemoembolization (DSM-TACE) in Intrahepatic Cholangiocellular Carcinoma (ICC): Results from a National Multi-Center Study on Safety and Efficacy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile D | 2017 |
Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bile Duct Neoplasms; Blotting, Western; Camellia sinens | 2009 |
Establishment and identification of the human multi-drug-resistant cholangiocarcinoma cell line QBC939/ADM.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Su | 2011 |
Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cholangiocarcinoma; Cytochrome P-450 | 2010 |
Tamoxifen reverses the multi-drug-resistance of an established human cholangiocarcinoma cell line in combined chemotherapeutics.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Casset | 2011 |
Chemoembolization of intrahepatic cholangiocarcinoma with cisplatinum, doxorubicin, mitomycin C, ethiodol, and polyvinyl alcohol: a 2-center study.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile | 2011 |
Transarterial chemoembolization in the treatment of patients with unresectable cholangiocarcinoma: Results and prognostic factors governing treatment success.
Topics: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Chemoembolization, Th | 2012 |
[Immune response of dendritic cells acquiring antigens from apoptotic cholangiocarcinoma cells induced by mitomycin].
Topics: Antigens, Neoplasm; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Co | 2003 |
Tannic acid synergizes the cytotoxicity of chemotherapeutic drugs in human cholangiocarcinoma by modulating drug efflux pathways.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfami | 2007 |
Palliative hepatic intraarterial chemotherapy (HIC) using a novel combination of gemcitabine and mitomycin C: results in hepatic metastases.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antine | 2008 |
Hepatic arterial infusion of mitomycin C with degradable starch microspheres for unresectable intrahepatic cholangiocarcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrah | 2008 |
[Transcatheter arterial chemo-embolization using degradable starch microspheres (DSM) markedly effective for post-hepatectomy intra-hepatic recurrence in a patient with cholangioma].
Topics: Aged; Antibiotics, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatoc | 2000 |