mitomycin has been researched along with Cell Transformation, Neoplastic in 29 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| " If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications." | 5.31 | [The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001) |
| " If Mitomycin is used in that low dosage and in that special application as shown, it could be a very efficient therapy with less complications." | 1.31 | [The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years]. ( Klaehsen, D; Maier, M; Merté, RL; Schmidt, M; Schmidt, T, 2001) |
| "The induction of neoplastic cell transformation is closely associated with DNA alterations which occur shortly after carcinogen exposure." | 1.27 | Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens. ( Amsbaugh, SC; DiPaolo, JA; Popescu, NC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (31.03) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Meyer, FB | 1 |
| Goebel, S | 1 |
| Spangel, SB | 1 |
| Leovsky, C | 1 |
| Hoelzer, D | 1 |
| Thierbach, R | 1 |
| Schmutz, JL | 1 |
| Trechot, P | 1 |
| El Ghamrasni, S | 1 |
| Cardoso, R | 1 |
| Halaby, MJ | 1 |
| Zeegers, D | 1 |
| Harding, S | 1 |
| Kumareswaran, R | 1 |
| Yavorska, T | 1 |
| Chami, N | 1 |
| Jurisicova, A | 1 |
| Sanchez, O | 1 |
| Hande, MP | 1 |
| Bristow, R | 1 |
| Hakem, R | 1 |
| Hakem, A | 1 |
| Liang, ZK | 1 |
| Zhang, L | 1 |
| Hu, ZM | 1 |
| Chen, Z | 1 |
| Huang, X | 1 |
| Shi, XH | 1 |
| Tan, WL | 1 |
| Gao, JM | 1 |
| Asur, RS | 1 |
| Thomas, RA | 1 |
| Tucker, JD | 1 |
| Chua, TC | 1 |
| Al-Zahrani, A | 1 |
| Saxena, A | 1 |
| Liauw, W | 1 |
| Zhao, J | 1 |
| Morris, DL | 1 |
| Tkocz, D | 1 |
| Crawford, NT | 1 |
| Buckley, NE | 1 |
| Berry, FB | 1 |
| Kennedy, RD | 1 |
| Gorski, JJ | 1 |
| Harkin, DP | 1 |
| Mullan, PB | 1 |
| Nohmi, T | 1 |
| Masumura, K | 1 |
| Ottey, M | 1 |
| Han, SY | 1 |
| Druck, T | 1 |
| Barnoski, BL | 1 |
| McCorkell, KA | 1 |
| Croce, CM | 1 |
| Raventos-Suarez, C | 1 |
| Fairchild, CR | 1 |
| Wang, Y | 1 |
| Huebner, K | 1 |
| Xue, WJ | 1 |
| Li, C | 1 |
| Zhou, XJ | 1 |
| Guan, HG | 1 |
| Qin, L | 1 |
| Li, P | 1 |
| Wang, ZW | 1 |
| Qian, HX | 1 |
| Falcone, G | 1 |
| Boettiger, D | 1 |
| Alemà, S | 1 |
| Tatò, F | 1 |
| Gruenert, DC | 1 |
| Cleaver, JE | 1 |
| Himori, T | 1 |
| Ujiie, S | 1 |
| Mimata, Y | 1 |
| Sugiyama, Z | 1 |
| Wakui, A | 1 |
| Schön, MP | 1 |
| Schön, M | 1 |
| Klein, CE | 1 |
| Blume, U | 1 |
| Bisson, S | 1 |
| Orfanos, CE | 1 |
| Levy, E | 1 |
| Baroche, C | 1 |
| Barret, JM | 1 |
| Alapetite, C | 1 |
| Salles, B | 1 |
| Averbeck, D | 1 |
| Moustacchi, E | 1 |
| Hei, TK | 1 |
| Liu, SX | 1 |
| Hall, EJ | 2 |
| Jones, SN | 1 |
| Sands, AT | 1 |
| Hancock, AR | 1 |
| Vogel, H | 1 |
| Donehower, LA | 1 |
| Linke, SP | 1 |
| Wahl, GM | 1 |
| Bradley, A | 1 |
| Hao, W | 1 |
| Messbarger, L | 1 |
| Joshi, SS | 1 |
| David-Pfeuty, T | 1 |
| Dolnikov, A | 1 |
| Millington, M | 1 |
| Sun, LQ | 1 |
| Symonds, G | 1 |
| Pagano, G | 1 |
| Korkina, LG | 1 |
| Schmidt, M | 1 |
| Maier, M | 1 |
| Schmidt, T | 1 |
| Klaehsen, D | 1 |
| Merté, RL | 1 |
| Bershadskiĭ, AD | 1 |
| Stavrovskaia, AA | 1 |
| Kamalati, T | 1 |
| McIvor, Z | 1 |
| Howard, M | 1 |
| Green, MR | 1 |
| Brooks, RF | 1 |
| Beug, H | 1 |
| Blundell, PA | 1 |
| Graf, T | 1 |
| Oikawa, T | 1 |
| Koga, Y | 1 |
| Tanahashi, K | 1 |
| Saito, T | 1 |
| Kobayashi, H | 1 |
| Kuzumaki, N | 1 |
| Tang, P | 1 |
| Xu, G | 1 |
| Chen, XH | 1 |
| Komatsu, K | 1 |
| Miller, RC | 1 |
| Popescu, NC | 1 |
| Amsbaugh, SC | 1 |
| DiPaolo, JA | 1 |
2 reviews available for mitomycin and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Gpt delta transgenic mouse: a novel approach for molecular dissection of deletion mutations in vivo.
Topics: Animals; Bone Marrow; Cell Transformation, Neoplastic; Colon; DNA Damage; DNA-Activated Protein Kina | 2004 |
Prospects for nutritional interventions in the clinical management of Fanconi anemia.
Topics: Anemia, Aplastic; Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Disease Progression; | 2000 |
27 other studies available for mitomycin and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Metformin alters therapeutic effects in the BALB/c tumor therapy model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; BALB 3T3 Cells; Carcinogens; Cell Survival; | 2021 |
[Subcutaneous panniculitis-like T-cell lymphoma following treatment with rituximab and cyclophosphamide].
Topics: Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Prot | 2013 |
Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.
Topics: Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA E | 2015 |
[A simple and efficient method for establishing a mouse model of orthotopic MB49 bladder cancer].
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Mice; Mi | 2009 |
Chemical induction of the bystander effect in normal human lymphoblastoid cells.
Topics: B-Lymphocyte Subsets; Bystander Effect; Cell Transformation, Neoplastic; Culture Media, Conditioned; | 2009 |
Secondary cytoreduction and perioperative intraperitoneal chemotherapy after initial debulking of pseudomyxoma peritonei: a study of timing and the impact of malignant dedifferentiation.
Topics: Adult; Antineoplastic Agents; Cell Differentiation; Cell Transformation, Neoplastic; Disease Progres | 2010 |
BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers.
Topics: Antineoplastic Agents; Base Sequence; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Prolif | 2012 |
Fhit-deficient normal and cancer cells are mitomycin C and UVC resistant.
Topics: Acid Anhydride Hydrolases; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; C | 2004 |
RASSF1A expression inhibits the growth of hepatocellular carcinoma from Qidong County.
Topics: Adult; Animals; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor | 2008 |
Role of cell division in differentiation of myoblasts infected with a temperature-sensitive mutant of Rous sarcoma virus.
Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Cell Differentiation; Cell Division; Ce | 1984 |
Sensitivity of mitomycin C and nitrogen mustard crosslinks to extreme alkaline conditions.
Topics: Antibiotics, Antineoplastic; Cell Transformation, Neoplastic; Cell Transformation, Viral; Centrifuga | 1984 |
Total tumor cell count and hematopoietic system of ah 109A-bearing rats treated with mitomycin C and carboquone.
Topics: Animals; Antineoplastic Agents; Azirines; Carbazilquinone; Carcinoma, Hepatocellular; Cell Transform | 1982 |
Carcinoma-associated 38-kD membrane glycoprotein MH 99/KS 1/4 is related to proliferation and age of transformed epithelial cell lines.
Topics: Antigens, Neoplasm; Cell Adhesion Molecules; Cell Division; Cell Line, Transformed; Cell Transformat | 1994 |
Activated ras oncogene and specifically acquired resistance to cisplatin in human mammary epithelial cells: induction of DNA cross-links and their repair.
Topics: Breast; Cell Division; Cell Line; Cell Line, Transformed; Cell Survival; Cell Transformation, Neopla | 1994 |
Oncogenic potential of bifunctional bioreductive drugs.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Survival; Cell Transformation, Neoplastic; Indolequ | 1996 |
The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.
Topics: Animals; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Crosses, Genet | 1996 |
Immunosuppression by metastatic lymphoma derived altered retroviral gp70 molecule.
Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; Gene Products, e | 1997 |
Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Death; Cell Lin | 1999 |
Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation.
Topics: Animals; Apoptosis; Blotting, Northern; Caffeine; Carcinogens; Cell Division; Cell Line; Cell Transf | 2000 |
[The treatment of a primary acquired melanosis of the conjunctiva with atypia by low dose of Mitomycin C 0.02 % - case report with follow up of 2 years].
Topics: Administration, Topical; Aged; Biopsy; Cell Transformation, Neoplastic; Conjunctiva; Conjunctival Ne | 2001 |
[The normalization of tumor cell morphology related to an increase in their size: research on giant cells produced by mitomycin C treatment].
Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoskeleton; Demecolcine; DNA, Ne | 1991 |
Expression of markers of differentiation in a transformed human keratinocyte line induced by coculture with a fibroblast line.
Topics: Animals; Antibodies, Monoclonal; Biomarkers; Cell Communication; Cell Differentiation; Cell Line; Ce | 1989 |
Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus.
Topics: Animals; Aphidicolin; Avian Leukosis Virus; Cell Differentiation; Cell Division; Cell Line; Cell Tra | 1987 |
Genetic background of high incidence of spontaneous tumors in BDX rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cell Transformation, Neoplastic; Killer Cells, Natural; Meth | 1986 |
[Study on the routine method of a short-term transforming test in mammalian cells in vitro for detecting carcinogens and promotors].
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Mes | 1986 |
The oncogenic potential of a combination of hyperthermia and chemotherapy agents.
Topics: Animals; Carmustine; Cell Survival; Cell Transformation, Neoplastic; Dactinomycin; Dose-Response Rel | 1988 |
Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens.
Topics: Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; | 1985 |