Page last updated: 2024-11-06

mitomycin and Cardiac Failure

mitomycin has been researched along with Cardiac Failure in 7 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Research Excerpts

ExcerptRelevanceReference
"Forty-six patients with recurrent metastatic breast cancer were treated with a combination chemotherapy including doxorubicin and mitomycin C."3.67Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C. ( Brambilla, MC; Comazzi, R; Genitoni, V; Guindani, A; Lacaita, G; Villani, F; Volonterio, A, 1985)
"A 23-year-old male patient with plasma cell leukemia showed characteristic clinical features: accelerating heart failure and consciousness disturbance accompanied with an increase of plasma cells in peripheral blood."1.29[Primary plasma cell leukemia complicated with high-output cardiac failure and hyperammonemia]. ( Hata, H; Kawaguchi, T; Kuribayashi, N; Matsuzaki, H; Nakahashi, E; Shimizu, K; Takatsuki, K; Tsuji, N, 1994)
"Two percent had congestive heart failure associated with doxorubicin."1.27Early and delayed clinical cardiotoxicity of doxorubicin. ( Blumenschein, GR; Buzdar, AU; Marcus, C; Smith, TL, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rjiba-Touati, K1
Ayed-Boussema, I1
Belarbia, A1
Mokni, M1
Achour, A1
Bacha, H1
Abid, S1
Nakahashi, E1
Kuribayashi, N1
Tsuji, N1
Kawaguchi, T1
Hata, H1
Matsuzaki, H1
Shimizu, K1
Takatsuki, K1
Mackintosh, J1
Sivanesaratnam, V1
Verweij, J1
Stoter, G1
Buzdar, AU1
Marcus, C1
Smith, TL1
Blumenschein, GR1
Villani, F1
Comazzi, R1
Lacaita, G1
Guindani, A1
Genitoni, V1
Volonterio, A1
Brambilla, MC1

Reviews

1 review available for mitomycin and Cardiac Failure

ArticleYear
Severe side effects of the cytotoxic drug mitomycin-C.
    The Netherlands journal of medicine, 1987, Volume: 30, Issue:1-2

    Topics: Animals; Heart Failure; Hepatic Veno-Occlusive Disease; Humans; Kidney Diseases; Mitomycin; Mitomyci

1987

Other Studies

6 other studies available for mitomycin and Cardiac Failure

ArticleYear
Role of recombinant human erythropoietin against mitomycin C-induced cardiac, hepatic and renal dysfunction in Wistar rats.
    Human & experimental toxicology, 2015, Volume: 34, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Chemical and Drug Induced Liver Injury; Drug A

2015
[Primary plasma cell leukemia complicated with high-output cardiac failure and hyperammonemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:8

    Topics: Adult; Ammonia; Antineoplastic Combined Chemotherapy Protocols; Cardiac Output; Dexamethasone; Doxor

1994
Cardiopulmonary complications of mitomycin-C.
    The Medical journal of Australia, 1990, Jan-01, Volume: 152, Issue:1

    Topics: Anemia, Hemolytic; Female; Heart Failure; Humans; Hypertension, Pulmonary; Middle Aged; Mitomycin; M

1990
Mitomycin-C cardiotoxicity.
    The Medical journal of Australia, 1989, Sep-04, Volume: 151, Issue:5

    Topics: Carcinoma, Squamous Cell; Female; Heart Failure; Humans; Middle Aged; Mitomycin; Mitomycins; Uterine

1989
Early and delayed clinical cardiotoxicity of doxorubicin.
    Cancer, 1985, Jun-15, Volume: 55, Issue:12

    Topics: Adult; Aged; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cyclo

1985
Possible enhancement of the cardiotoxicity of doxorubicin when combined with mitomycin C.
    Medical oncology and tumor pharmacotherapy, 1985, Volume: 2, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

1985