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mitomycin and Carcinoma 256, Walker

mitomycin has been researched along with Carcinoma 256, Walker in 20 studies

Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.

Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" The pharmacokinetic analysis revealed that macromolecular conjugation reduced elimination of MMC from the poorly-perfused region rather than well-perfused region."1.30Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection. ( Hashida, M; Honda, K; Morita, S; Nomura, T; Saikawa, A; Sakaeda Kakutani, T; Takakura, Y; Yamashita, F, 1998)
"The median survival periods for stomach cancer (Stage 4) after non-radical surgery by means of intraarterial chemotherapy with and without noradrenaline were, respectively, 12 months (n = 8) and 5."1.27[Intra-arterial infusion chemotherapy combine with noradrenalin administration (an improved antitumor effect using a cancerous blood vessel]. ( Katsumi, S; Kawaguchi, T; Murai, T; Sato, T, 1985)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's9 (45.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TANAKA, N1
Jauhiainen, K1
Kangas, L1
Nieminen, AL1
Käpylä, H1
Alfthan, O1
Nomura, T1
Saikawa, A1
Morita, S1
Sakaeda Kakutani, T1
Yamashita, F1
Honda, K1
Takakura, Y3
Hashida, M3
Imoto, H2
Sakamura, Y1
Ohkouchi, K2
Atsumi, R1
Sezaki, H2
Satou, T2
Walton, MI2
Sugget, N1
Workman, P2
Smith, PJ1
Sato, T11
Sekine, S2
Katsumi, S4
Kawaguchi, T3
Murai, T1

Other Studies

20 other studies available for mitomycin and Carcinoma 256, Walker

ArticleYear
EFFECT OF PHLEOMYCIN ON DNA POLYMERASE OF TUMOR ORIGIN.
    The Journal of antibiotics, 1965, Volume: 18

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma 256, Walker; DNA-Directed DNA Polymerase; Mi

1965
Optimising mitomycin C activity during intravesical instillation.
    Urological research, 1983, Volume: 11, Issue:2

    Topics: Animals; Buffers; Carcinoma 256, Walker; Cell Line; Drug Stability; Hydrogen-Ion Concentration; Mito

1983
Pharmacokinetic characteristics and therapeutic effects of mitomycin C-dextran conjugates after intratumoural injection.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Mar-31, Volume: 52, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma 256, Walker; Dextrans; Female; Injections, Intralesi

1998
Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Animals; Capillary Permeability; Carcinoma 256, Walker; Dextrans; Extracellular Space; Female; Mitom

1992
[Warmed water administered into tumor feeding artery via percutan-trans-catheter (PTC) as thermotherapy after chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:10 Suppl

    Topics: Animals; Carcinoma 256, Walker; Glucose; Hot Temperature; Injections, Intra-Arterial; Male; Mitomyci

1992
The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:4

    Topics: Animals; Antineoplastic Agents; Aziridines; Carcinoma 256, Walker; Cell Hypoxia; Colonic Neoplasms;

1992
The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9.
    Cancer communications, 1991, Volume: 3, Issue:7

    Topics: Animals; Antineoplastic Agents; Aziridines; Biotransformation; Carcinoma 256, Walker; Colonic Neopla

1991
[Circadian-rhythm of tumor growth in non-vascularized tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Animals; Carcinoma 256, Walker; Circadian Rhythm; Combined Modality Therapy; Hot Temperature; Male;

1991
Disposition of anticancer drugs after bolus arterial administration in a tissue-isolated tumor perfusion system.
    Cancer research, 1990, Mar-01, Volume: 50, Issue:5

    Topics: Animals; Carcinoma 256, Walker; Doxorubicin; Female; Fluorouracil; Infusions, Intra-Arterial; Mitomy

1990
[Enhancing hyperthermic cytotoxicity in Walker-256 by intraarterial injection of warmed saline].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 2

    Topics: Animals; Carcinoma 256, Walker; Combined Modality Therapy; Hyperthermia, Induced; Injections, Intra-

1990
[Warm drug solution injected into tumor vessel may enhance antitumor effect].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 2

    Topics: Animals; Body Temperature; Carcinoma 256, Walker; Combined Modality Therapy; Female; Glucose; Humans

1990
[Microvascular injury in hyperthermia by injecting warm water using noradrenaline into tumor feeding artery-induced tumor necrosis of Walker-256].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:8 Pt 2

    Topics: Animals; Arteries; Carcinoma 256, Walker; Combined Modality Therapy; Endothelium, Vascular; Hyperthe

1989
[Enhancement of antitumor effect induced by ischemia in intraarterial chemotherapy (experimental study)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Embolization, Therapeutic; Infusions, Intra-Arterial; Male; Mitomyci

1987
[Short ischemia of tumor by noradrenalin injected into tumor-feeding arteries after chemotherapy-improved cytotoxic damage on Walker-256].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 1

    Topics: Animals; Carcinoma 256, Walker; Injections, Intra-Arterial; Male; Mitomycin; Mitomycins; Norepinephr

1987
[Enhancement of the antitumor effect on Walker-256 of administration of noradrenaline in physiological saline for five minutes after intraarterial injection of MMC].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Animals; Carcinoma 256, Walker; Injections, Intra-Arterial; Male; Mitomycin; Mitomycins; Norepinephr

1987
[Enhancement of antitumor effect of MMC on Walker 256 by intra-arterial administration of noradrenaline in hyperthermia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Animals; Carcinoma 256, Walker; Combined Modality Therapy; Hyperthermia, Induced; Injections, Intra-

1988
[Enhancement of Walker-256 antitumor effect by intra-arterial administration of TNF before using mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8 Pt 2

    Topics: Animals; Carcinoma 256, Walker; Drug Synergism; Injections, Intravenous; Male; Mitomycin; Mitomycins

1988
[Intra-arterial chemotherapy with nor-adrenaline. Experimental study 1 (enhancement of anti-tumor effect and tumor vessels)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:6

    Topics: Animals; Capillary Permeability; Carcinoma 256, Walker; Drug Synergism; Evans Blue; Infusions, Intra

1985
[Enhancement of anti-cancer effect by increased injection pressure of a single shot in intra-arterial chemotherapy--the advantage of using noradrenaline in intra-arterial chemotherapy. An experimental study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:7

    Topics: Animals; Carcinoma 256, Walker; Injections, Intra-Arterial; Male; Mitomycin; Mitomycins; Norepinephr

1985
[Intra-arterial infusion chemotherapy combine with noradrenalin administration (an improved antitumor effect using a cancerous blood vessel].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma 256, Walker; Doxorubicin; Humans;

1985