mitomycin has been researched along with Carcinoma, Lewis Lung in 7 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three mouse cancer cell lines [CT26 mouse colon cancer cells, B16 melanoma cells and Lewis lung carcinoma (LLC)], 5 human carcinoma cell lines (human esophageal squamous cell carcinoma cell lines TE8 and HEC46 and the human pancreatic carcinoma cell lines PK-9, AsPC-1 and SUIT-2) and 5 chemotherapeutic agents [mitoxantrone (MIT), mitomycin C(MMC), 5-fluorouracil (5FU), camptothecin (CPT-11) and cisplatin (CDDP)] that are frequently used in a clinical setting for cancer treatment were utilized to investigate the surface expression level of calreticulin and HLA class I after exposure to chemotherapeutic agents." | 3.81 | The key role of calreticulin in immunomodulation induced by chemotherapeutic agents. ( Hirano, S; Kuroda, A; Kuwatani, T; Kyogoku, N; Maki, T; Miyauchi, K; Shichinohe, T; Takeuchi, S; Tsuchikawa, T; Wada, M; Yamamura, Y, 2015) |
| "The LD50 of pentamidine on cancer cells maintained in vitro is correlated with the endo-exonuclease enzyme activity." | 1.32 | The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer. ( Alaoui-Jamali, MA; Chow, TY; Griller, D; Yeh, C; Yuen, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murakami, N | 1 |
| Tamura, S | 1 |
| Koyama, K | 1 |
| Sugimoto, M | 1 |
| Maekawa, R | 1 |
| Kobayashi, M | 1 |
| Kostková, H | 1 |
| Etrych, T | 1 |
| Ríhová, B | 1 |
| Kostka, L | 1 |
| Starovoytová, L | 1 |
| Kovář, M | 1 |
| Ulbrich, K | 1 |
| Yamamura, Y | 1 |
| Tsuchikawa, T | 1 |
| Miyauchi, K | 1 |
| Takeuchi, S | 1 |
| Wada, M | 1 |
| Kuwatani, T | 1 |
| Kyogoku, N | 1 |
| Kuroda, A | 1 |
| Maki, T | 1 |
| Shichinohe, T | 1 |
| Hirano, S | 1 |
| Inami, M | 1 |
| Kawamura, I | 1 |
| Tsujimoto, S | 1 |
| Nishigaki, F | 1 |
| Matsumoto, S | 1 |
| Naoe, Y | 1 |
| Sasakawa, Y | 1 |
| Matsuo, M | 1 |
| Manda, T | 1 |
| Goto, T | 1 |
| Chow, TY | 1 |
| Alaoui-Jamali, MA | 1 |
| Yeh, C | 1 |
| Yuen, L | 1 |
| Griller, D | 1 |
| Sigounas, G | 1 |
| Sallah, S | 1 |
| Sigounas, VY | 1 |
| Peer, D | 1 |
| Dekel, Y | 1 |
| Melikhov, D | 1 |
| Margalit, R | 1 |
7 other studies available for mitomycin and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cytotoxins; Depsipeptides; Dose-Response Rela | 2004 |
HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.
Topics: Acrylamides; Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Lewis Lung; Cell Line, Tumor; Cyt | 2013 |
The key role of calreticulin in immunomodulation induced by chemotherapeutic agents.
Topics: Animals; Antigens, Surface; Antineoplastic Agents; Apoptosis; Calreticulin; Camptothecin; Carcinoma, | 2015 |
Effects of FK317, a novel anti-cancer agent, on survival of mice bearing B16BL6 melanoma and Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Drug Evaluation; Female; Melanoma, Experiment | 2002 |
The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; | 2004 |
Erythropoietin modulates the anticancer activity of chemotherapeutic drugs in a murine lung cancer model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Lewis Lung; Cisplatin; C | 2004 |
Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Lewis Lung; Cell Line, Tumor; Disease P | 2004 |