mitomycin has been researched along with Carcinoma, Large Cell in 10 studies
Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
mitomycin : A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae.
Carcinoma, Large Cell: A tumor of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Secondary objectives were time to disease progression, response rates, evaluation of toxicity, disease-related symptoms, World Health Organization performance status (PS), and quality of life (QoL)." | 2.71 | Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma. ( Anderson, H; Ashcroft, L; Beresford, C; Burt, PA; Clemons, M; Danson, S; Dowd, I; Fairve-Finn, C; Hassan, J; Middleton, MR; O'Byrne, KJ; Ranson, M; Stout, R; Thatcher, N, 2003) |
| " Pathological findings diagnosed undifferentiated carcinoma (large cell type) of thymus, the patient underwent radiation therapy of the mediastinum at a total dosage of 50 Gy and chemotherapy [cisplatin (CDDP) + vinorelbine ditartrate + mitomycin C (MMC)]." | 1.32 | [Thymic carcinoma incidentally detected on routine chest computed tomography; report of a case]. ( Ida, M; Kita, Y; Neyatani, H; Nogimura, H; Shundo, Y, 2004) |
| " To explain this tumor selectivity, the distribution of FK317 was investigated after dosing tumor-bearing mice with the 14C-labelled compound." | 1.30 | FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice. ( Fujiwara, T; Inami, M; Kawamura, I; Manda, T; Matsumoto, S; Naoe, Y; Nishigaki, F; Shimomura, K; Takagaki, S; Tsujimoto, S; Yamazaki, S, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 9 (90.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danson, S | 1 |
| Middleton, MR | 1 |
| O'Byrne, KJ | 1 |
| Clemons, M | 1 |
| Ranson, M | 1 |
| Hassan, J | 1 |
| Anderson, H | 1 |
| Burt, PA | 1 |
| Fairve-Finn, C | 1 |
| Stout, R | 1 |
| Dowd, I | 1 |
| Ashcroft, L | 2 |
| Beresford, C | 1 |
| Thatcher, N | 2 |
| Shundo, Y | 1 |
| Kita, Y | 1 |
| Nogimura, H | 1 |
| Ida, M | 1 |
| Neyatani, H | 1 |
| Yamazaki, S | 2 |
| Sekine, I | 1 |
| Matsuno, Y | 1 |
| Takei, H | 1 |
| Yamamoto, N | 1 |
| Kunitoh, H | 1 |
| Ohe, Y | 1 |
| Tamura, T | 1 |
| Kodama, T | 1 |
| Asamura, H | 1 |
| Tsuchiya, R | 1 |
| Saijo, N | 1 |
| Takeda, S | 1 |
| Funakoshi, Y | 1 |
| Kadota, Y | 1 |
| Koma, M | 1 |
| Maeda, H | 1 |
| Kawamura, S | 1 |
| Matsubara, Y | 1 |
| Booton, R | 1 |
| Ward, T | 1 |
| Morris, J | 1 |
| Heighway, J | 1 |
| Naoe, Y | 1 |
| Inami, M | 1 |
| Matsumoto, S | 1 |
| Takagaki, S | 1 |
| Fujiwara, T | 1 |
| Kawamura, I | 1 |
| Nishigaki, F | 1 |
| Tsujimoto, S | 1 |
| Manda, T | 1 |
| Shimomura, K | 1 |
| Itakura, K | 1 |
| Mouri, T | 1 |
| Arizumi, T | 1 |
| Suzuki, J | 1 |
| Chida, H | 1 |
| Saito, T | 1 |
| Ishida, T | 1 |
| Aoki, H | 1 |
| Kuwahara, K | 1 |
| Minegishi, Y | 1 |
| Watanabe, K | 1 |
| Okano, T | 1 |
| Hashimoto, K | 1 |
| Hayashihara, K | 1 |
| Watanabe, S | 1 |
| Nemoto, E | 1 |
| Fukai, S | 1 |
| Yanai, N | 1 |
| Johnston, MR | 1 |
| Mullen, JB | 1 |
| Pagura, ME | 1 |
| Howard, RB | 1 |
| Atagi, S | 1 |
| Kawahara, M | 1 |
| Hosoe, S | 1 |
| Ogawara, M | 1 |
| Kawaguchi, T | 1 |
| Okishio, K | 1 |
| Naka, N | 1 |
| Sunami, T | 1 |
| Mitsuoka, S | 1 |
| Akira, M | 1 |
3 trials available for mitomycin and Carcinoma, Large Cell
| Article | Year |
|---|---|
Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Carboplatin; C | 2003 |
ERCC1 mRNA expression is not associated with response and survival after platinum-based chemotherapy regimens in advanced non-small cell lung cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Large Cell; | 2007 |
A phase II study of continuous concurrent thoracic radiotherapy in combination with mitomycin, vindesine and cisplatin in unresectable stage III non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; | 2002 |
7 other studies available for mitomycin and Carcinoma, Large Cell
| Article | Year |
|---|---|
[Thymic carcinoma incidentally detected on routine chest computed tomography; report of a case].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Cisplatin; Combined Modality | 2004 |
Clinical responses of large cell neuroendocrine carcinoma of the lung to cisplatin-based chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; | 2005 |
Fall in diffusing capacity associated with induction therapy for lung cancer: a predictor of postoperative complication?
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carbon Monoxide; Carcinoma, La | 2006 |
FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biotransformation; Body Weight; Carcinoma, Large Cel | 1998 |
[A case of large-cell lung cancer responding remarkably to combination chemotherapy with vinorelbine, mitomycin C and carboplatin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Large Cell; Drug Administrat | 2000 |
[Effectiveness of docetaxel plus cisplatin in large cell lung cancer showing little response to prior chemotherapy with MVP].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell; Cisplatin; Docetaxel; Drug Ad | 2000 |
Validation of an orthotopic model of human lung cancer with regional and systemic metastases.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Carcinoma, Large Cell; Cisplatin; Disease Mode | 2001 |